Faculty profile

Yan Burelle

Back to faculty

Full ProfessorUniversity of Ottawa

Yan Burelle

Full Professor

Faculty of Health Sciences

University of Ottawa

Ottawa, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
15 publications in the last five years, latest in 2026.
Senior (last) author on 3 recent papers, a sign of leading a research group.
Principal investigator on 5 research grants (3 CIHR, 2 NSERC), most recently in 2025.
Supervised 1 trainee who won CIHR awards, most recently in 2017.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

University Profile Search on Google Scholar

Find them onX · LinkedIn · Bluesky · YouTube

Signals and details

Research

Read how they describe their research on their University of Ottawa profile.

Muscle Regeneration Muscle Stem Cells Aging Fate Decision Metabolism Myogenesis Perixosomes Mitochondria

Latest papers

Functional and metabolomic analyses of brown adipose tissue during cold-deacclimation reveal rapid N-acetylated amino acid adaptations.
iScience · 2026
Mitochondria in muscle stem cell biology: gatekeepers of fate, function, and regeneration.
American journal of physiology. Cell physiology · 2026 · senior author
Canagliflozin Promotes Structural and Functional Changes in Proximal Tubular Cell Mitochondria of Hypertensive-Diabetic Mice.
International journal of molecular sciences · 2025

All 32 publications

Latest funding

Peroxisomes: A neglected metabolic organelle with a crucial role in the regulation of muscle stem cell regenerative properties
CIHR · 2025 · Nominated PI
$753,526
Mitochondrial Quality Control in Muscle Stem Cells: A Determinant of Cell Fate Decision and Tissue Repair Capacity.
CIHR · 2022 · Nominated PI
$692,325
Mitochondrial quality control in striated muscle
NSERC · 2022 · Principal investigator
$120,000

All 8 grants and awards

32 publications.

Functional and metabolomic analyses of brown adipose tissue during cold-deacclimation reveal rapid N-acetylated amino acid adaptations.

Pileggi CA, McIlroy E, Hamilton LMK, Kuksal N, Kennedy LS, Vasilyeva V, Kanaan MN, El Hankouri Z, Burelle Y, Cuperlovic-Culf M, Harper ME

iScience2026

DOI: 10.1016/j.isci.2026.115146 PMID: 41869569

Mitochondria in muscle stem cell biology: gatekeepers of fate, function, and regeneration.

Khacho M, Burelle Y

American journal of physiology. Cell physiology2026Senior author

DOI: 10.1152/ajpcell.00027.2026 PMID: 41778679

Canagliflozin Promotes Structural and Functional Changes in Proximal Tubular Cell Mitochondria of Hypertensive-Diabetic Mice.

Trentin-Sonoda M, Burelle Y, Gutsol A, Myette RL, Hébert RL

International journal of molecular sciences2025

DOI: 10.3390/ijms262411988 PMID: 41465415

Extracellular Vesicle Mitochondrial DNA Reflects Podocyte Mitochondrial Stress and Is Associated with Relapse in Nephrotic Syndrome.

Myette RL, Holterman CE, Trentin-Sonoda M, Cooper TT, Lajoie GA, Cairns G, Burelle Y, El Khatib N, Raman-Nair J, Burger D, Kennedy CRJ

International journal of molecular sciences2025

DOI: 10.3390/ijms26157245 PMID: 40806378

PINK1 deficiency alters muscle stem cell fate decision and muscle regenerative capacity.

Cairns G, Thumiah-Mootoo M, Abbasi MR, Gourlay M, Racine J, Larionov N, Prola A, Khacho M, Burelle Y

Stem cell reports2024Senior author

DOI: 10.1016/j.stemcr.2024.03.004 PMID: 38579709

A genetic mouse model of lean-NAFLD unveils sexual dimorphism in the liver-heart axis.

Burelle C, Clapatiuc V, Deschênes S, Cuillerier A, De Loof M, Higgins MÈ, Boël H, Daneault C, Chouinard B, Clavet MÉ, Tessier N, Croteau I, Chabot G, Martel C, Sirois MG, Lesage S, Burelle Y, Ruiz M

Communications biology2024

DOI: 10.1038/s42003-024-06035-6 PMID: 38519536

Perturbations in lipid metabolism and gut microbiota composition precede cardiac dysfunction in a mouse model of thalassemia.

Liu Y, Fillebeen C, Forest A, Botta A, Varin TV, Marette A, Burelle Y, Des Rosiers C, Pantopoulos K, Sweeney G

FASEB journal : official publication of the Federation of American Societies for Experimental Biology2023

DOI: 10.1096/fj.202301043r PMID: 37902616

Radiation induces long-term muscle fibrosis and promotes a fibrotic phenotype in fibro-adipogenic progenitors.

Collao N, D'Souza D, Messeiller L, Pilon E, Lloyd J, Larkin J, Ngu M, Cuillerier A, Green AE, Menzies KJ, Burelle Y, De Lisio M

Journal of cachexia, sarcopenia and muscle2023

DOI: 10.1002/jcsm.13320 PMID: 37671686

Discovery-Based Proteomics Identify Skeletal Muscle Mitochondrial Alterations as an Early Metabolic Defect in a Mouse Model of β-Thalassemia

Reboucas P, Fillebeen C, Botta A, Cleverdon R, Steele AP, Richard V, Zahedi RP, Borchers CH, Burelle Y, Hawke TJ

International Journal of Molecular Sciences20231 citations

DOI: 10.3390/ijms24054402

Right Ventricular Maladaptation to Pressure Overload in Fischer Rats Is Associated With Profound Deficiency in Adenylate Kinase 1 and Impaired Ventricular Energetics.

Zelt JGE, Cadete V, Deng Y, Godoy R, Cuillerier A, Rowe K, Abdul-Ghani M, Megeney L, Burelle Y, Giulivi A, Stewart AFR, Provencher S, Breuils-Bonnet S, Bonnet S, deKemp R, Beanlands R, Mielniczuk LM, Stewart DJ

Hypertension (Dallas, Tex. : 1979)2022

DOI: 10.1161/hypertensionaha.122.19300 PMID: 36278405

Peroxisomes: A neglected metabolic organelle with a crucial role in the regulation of muscle stem cell regenerative properties

Nominated PICIHR2025Project Grant

Principal investigators: Burelle, Yan

Keywords: Aging; Fate Decision; Metabolism; Muscle Regeneration; Muscle Stem Cells; Myogenesis; Perixosomes

$753,526

Mitochondrial Quality Control in Muscle Stem Cells: A Determinant of Cell Fate Decision and Tissue Repair Capacity.

Nominated PICIHR2022Project Grant

Principal investigators: Burelle, Yan

Keywords: Mitochondria; Mitophagy; Muscle Regeneration; Muscle Stem Cells

$692,325

Mitochondrial quality control in striated muscle

Principal investigatorNSERC2022Discovery Grants Program - Individual

Principal investigators: Burelle, Yan

$120,000

Mitochondrial dysfunction in sepsis-induced cardiac dysfunction

Nominated PICIHR2020Project Grant

Principal investigators: Burelle, Yan

Keywords: Mitochondria-Targeted Therapy; Mitochondrial Dysfunction; Mitochondrial Quality Control; Sepsis; Vital Organ Failure

$707,626

Metabolomics Advanced Training and International Exchange (CREATE-MATRIX)

Co-investigatorNSERC2018Collaborative Research and Training Experience

Principal investigators: Harper, MaryEllen

$1,650,000

Saltin International PhD Course in Clinical and Exercise Physiology

Co-investigatorCIHR2017Planning and Dissemination Grant - Institute Community Support

Principal investigators: Wright, David

Keywords: Adipose Tissue; Aging; Cardiovascular Disease; Diabetes; Exercise; Maternal Health; Nutrition; Obesity; Sex Differences; Skeletal Muscle

$20,000

Molecular pathophysiology and stem cell treatment for mitochondrial diseases: insights from the French Canadian variant of Leigh Syndrome

SupervisorCIHR2017Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Cuillerier, Alexanne

Keywords: Bioenergetics; Genetic Mitochondrial Diseases; Leigh Syndrome; Liver; Lrpprc; Mesenchymal Stem Cells; Mitochondria; Mitochondrial Dysfunctions; Physiology; Stem Cell Therapy

$105,000

UNDERSTANDING THE ROLE OF MITOCHONDRIAL QUALITY CONTROL

Principal investigatorNSERC2016Discovery Grants Program - Individual

Principal investigators: Burelle, Yan

$186,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

Something wrong or missing on this profile? Suggest a correction

Yan Burelle

Research

Latest papers

Latest funding

Functional and metabolomic analyses of brown adipose tissue during cold-deacclimation reveal rapid N-acetylated amino acid adaptations.

Mitochondria in muscle stem cell biology: gatekeepers of fate, function, and regeneration.

Canagliflozin Promotes Structural and Functional Changes in Proximal Tubular Cell Mitochondria of Hypertensive-Diabetic Mice.

Extracellular Vesicle Mitochondrial DNA Reflects Podocyte Mitochondrial Stress and Is Associated with Relapse in Nephrotic Syndrome.

PINK1 deficiency alters muscle stem cell fate decision and muscle regenerative capacity.

A genetic mouse model of lean-NAFLD unveils sexual dimorphism in the liver-heart axis.

Perturbations in lipid metabolism and gut microbiota composition precede cardiac dysfunction in a mouse model of thalassemia.

Radiation induces long-term muscle fibrosis and promotes a fibrotic phenotype in fibro-adipogenic progenitors.

Discovery-Based Proteomics Identify Skeletal Muscle Mitochondrial Alterations as an Early Metabolic Defect in a Mouse Model of β-Thalassemia

Right Ventricular Maladaptation to Pressure Overload in Fischer Rats Is Associated With Profound Deficiency in Adenylate Kinase 1 and Impaired Ventricular Energetics.

Peroxisomes: A neglected metabolic organelle with a crucial role in the regulation of muscle stem cell regenerative properties

Mitochondrial Quality Control in Muscle Stem Cells: A Determinant of Cell Fate Decision and Tissue Repair Capacity.

Mitochondrial quality control in striated muscle

Mitochondrial dysfunction in sepsis-induced cardiac dysfunction

Metabolomics Advanced Training and International Exchange (CREATE-MATRIX)

Saltin International PhD Course in Clinical and Exercise Physiology

Molecular pathophysiology and stem cell treatment for mitochondrial diseases: insights from the French Canadian variant of Leigh Syndrome

UNDERSTANDING THE ROLE OF MITOCHONDRIAL QUALITY CONTROL

Frequent collaborators

Mary-Ellen Harper

Mireille Khacho

Christine Des Rosiers

Gary Sweeney

Matthieu Ruiz

Miroslava Cuperlovic-Culf

Michael De Lisio

Gabriel Altit

Gabriel Altit

Jean Michaud

Robert deKemp

Yan Burelle

Thomas Hawke

Rob Beanlands

Dylan Burger

Eli Puterman

Catherine Martel

Sylvie Lesage

Pranesh Chakraborty

Steeve Provencher

Reggie Hamdy

Colin Crist

Murray Baron

Lynn Megeney