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Research
Latest papers
A Rapid Assay for Hepatitis C Virus RNA Detection Using Reverse-Transcription Loop-Mediated Isothermal Amplification-Coupled CRISPR-Cas12b-Based Strategy.
The Journal of infectious diseases · 2026
Sex differences in kidney metabolism may reflect sex-dependent outcomes in human diabetic kidney disease
Science Translational Medicine · 2024
Single-cell, single-nucleus, and spatial transcriptomics characterization of the immunological landscape in the healthy and PSC human liver.
Journal of hepatology · 2024
Latest funding
- $1,690,650
A strategy for using machine intelligence to design high-capacity viral vectors that evade pre-existing immunity and enable gene therapies for diseases involving defects in large genes.
CIHR · 2025 · Co-investigator
- $100,000
T cell receptor sequences provide a fingerprint to define features of T cell immunity responsible for cure in chronic hepatitis B patients.
CIHR · 2024 · Nominated PI
- $1,373,176
Characterization of key aspects of a controlled human infection model (CHIM) for hepatitis C virus (HCV) infection
CIHR · 2023 · Co-investigator
6 publications.
A Rapid Assay for Hepatitis C Virus RNA Detection Using Reverse-Transcription Loop-Mediated Isothermal Amplification-Coupled CRISPR-Cas12b-Based Strategy.
Chowdhury A, Garcia BG, Zahoor MA, ElMawla NF, Davidson AR, Wyatt HDM, Maxwell KL, Mahassine A, Gehring A, Feld JJ
Sex differences in kidney metabolism may reflect sex-dependent outcomes in human diabetic kidney disease
Clotet-Freixas S, Zaslaver O, Kotlyar M, Pastrello C, Quaile AT, McEvoy CM, Saha AD, Farkona S, Boshart A, Zorcic K
Single-cell, single-nucleus, and spatial transcriptomics characterization of the immunological landscape in the healthy and PSC human liver.
Andrews TS, Nakib D, Perciani CT, Ma XZ, Liu L, Winter E, Camat D, Chung SW, Lumanto P, Manuel J, Mangroo S, Hansen B, Arpinder B, Thoeni C, Sayed B, Feld J, Gehring A, Gulamhusein A, Hirschfield GM, Ricciuto A, Bader GD, McGilvray ID, MacParland S
A roadmap for serum biomarkers for hepatitis B virus: current status and future outlook.
Kramvis A, Chang KM, Dandri M, Farci P, Glebe D, Hu J, Janssen HLA, Lau DTY, Penicaud C, Pollicino T, Testoni B, Van Bömmel F, Andrisani O, Beumont-Mauviel M, Block TM, Chan HLY, Cloherty GA, Delaney WE, Geretti AM, Gehring A, Jackson K, Lenz O, Maini MK, Miller V, Protzer U, Yang JC, Yuen MF, Zoulim F, Revill PA
Hepatitis B virus-specific CD4 T cell responses differentiate functional cure from chronic surface antigen+ infection.
Hoogeveen RC, Dijkstra S, Bartsch LM, Drescher HK, Aneja J, Robidoux MP, Cheney JA, Timm J, Gehring A, de Sousa PSF, Ximenez L, Peliganga LB, Pitts A, Evans FB, Boonstra A, Kim AY, Lewis-Ximenez LL, Lauer GM
Getting to HBV cure: The promising paths forward.
Fung S, Choi HSJ, Gehring A, Janssen HLA
A strategy for using machine intelligence to design high-capacity viral vectors that evade pre-existing immunity and enable gene therapies for diseases involving defects in large genes.
Principal investigators: Garton, Michael J
Keywords: Viral Vector Design
T cell receptor sequences provide a fingerprint to define features of T cell immunity responsible for cure in chronic hepatitis B patients.
Principal investigators: Gehring, Adam J
Keywords: Hepatitis B Virus; Human; Liver; Single-Cell Rna Sequencing; T Cell
Characterization of key aspects of a controlled human infection model (CHIM) for hepatitis C virus (HCV) infection
Principal investigators: Feld, Jordan J; Houghton, Michael; Shoukry, Naglaa H; Tyrrell, D. Lorne J
Keywords: Acute Infection; Cancer Prevention; Controlled Human Infection Model (Chim); Hepatitis C Virus; Immune Response; Spontaneous Clearance; Vaccine
A generative AI strategy to reducing immunogenicity of synthetic and autoantigen proteins
Principal investigators: Garton, Michael
Keywords: Synthetic biology; Protein design; Generative AI; Autoimmunity; Human leucocyte antigen display
Characterization of key aspects of a controlled human infection model (CHIM) for hepatitis C virus (HCV) infection
Principal investigators: Feld, Jordan J; Houghton, Michael; Shoukry, Naglaa H; Tyrrell, D. Lorne J
Keywords: Acute Infection; Cancer Prevention; Controlled Human Infection Model (Chim); Hepatitis C Virus; Immune Response; Spontaneous Clearance; Vaccine
Hepatitis B virus-mediated liver inflammation induces a novel monocyte-derived macrophage with an inflammatory profile to drive hepatitis B pathogenesis.
Principal investigators: Gehring, Adam J
Keywords: Hepatitis B Virus; Human; Inflammation; Liver; Macrophage; Organoids; Stem Cells
Definition of a novel monocyte-derived macrophage population in the inflamed human liver.
Principal investigators: Gehring, Adam J
Keywords: Hepatitis B Virus; Human; Inflammation; Liver; Macrophage; Organoids; Stem Cells
Peginterferon lambda to treat outpatients with COVID-19 to prevent severe disease: Focus on variants of concern
Principal investigators: Feld, Jordan J
Keywords: Covid-19; Host Antiviral Response; Pan-Variant; Pegylated Interferon Lambda; Prevention Of Hospitalization And Mortality; Randomized Controlled Trial; Reduction In Viral Load; Simplified Outpatient Treatment; Transmission Prevention; Variants Of Concern
Defining and Targeting Autoimmune Liver Disease
Principal investigators: MacParland, Sonya; Bader, Gary D; Feld, Jordan J; Mcgilvray, Ian D
Keywords: Adult Liver; Bioinformatics; Human Immunology; Liver Immunology; Paediatric Liver; Pathway Analysis; Primary Sclerosing Cholangitis; Single Cell Rna Sequencing
Defining and Targeting Autoimmune Liver Disease
Principal investigators: MacParland, Sonya; Bartczak, Agata; Feld, Jordan J; Mcgilvray, Ian D
Keywords: Autoimmune Liver Disease; Immunology; Liver
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Jordan Feld and Jordan Feld: 38 shared papers
- Sergi Clotet-Freixas and Ana Konvalinka: 18 shared papers
- Igor Jurisica and Ana Konvalinka: 12 shared papers
- Sergi Clotet-Freixas and Igor Jurisica: 8 shared papers
- Sonya MacParland and Amanda Ricciuto: 4 shared papers
- Minna Woo and Igor Jurisica: 3 shared papers
- Minna Woo and Ana Konvalinka: 2 shared papers
- Jordan Feld and Sonya MacParland: 2 shared papers
- Sonya MacParland and Jordan Feld: 2 shared papers
- Sergi Clotet-Freixas and Denis Soulet: 1 shared paper
- Sergi Clotet-Freixas and Minna Woo: 1 shared paper
- Sergi Clotet-Freixas and Brandy Wicklow: 1 shared paper
- Sergi Clotet-Freixas and Adam Gehring: 1 shared paper
- Denis Soulet and Minna Woo: 1 shared paper
- Denis Soulet and Igor Jurisica: 1 shared paper
- Denis Soulet and Brandy Wicklow: 1 shared paper
- Denis Soulet and Adam Gehring: 1 shared paper
- Minna Woo and Brandy Wicklow: 1 shared paper
- Minna Woo and Adam Gehring: 1 shared paper
- Igor Jurisica and Adam Gehring: 1 shared paper
- Jordan Feld and Adam Gehring: 1 shared paper
- Jordan Feld and Amanda Ricciuto: 1 shared paper
- Brandy Wicklow and Adam Gehring: 1 shared paper
- Ana Konvalinka and Adam Gehring: 1 shared paper
- Sonya MacParland and Adam Gehring: 1 shared paper
- Adam Gehring and Amanda Ricciuto: 1 shared paper
- Adam Gehring and Jordan Feld: 1 shared paper
- Medicine
- Medicine/Nephrology
- Pediatrics and Child Health
- Rheumatology
- School of Nursing
- Department of Laboratory Medicine and Pathobiology
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Amanda Ricciuto
Faculty
1 shared papers, latest 2024
Jordan Feld
School of Nursing
1 shared papers, latest 2024
Sergi Clotet-Freixas
Medicine
1 shared papers, latest 2024
Denis Soulet
Faculty
1 shared papers, latest 2024
Minna Woo
Medicine
1 shared papers, latest 2024
Igor Jurisica
Rheumatology
1 shared papers, latest 2024
Jordan Feld
Medicine
1 shared papers, latest 2024
Brandy Wicklow
Pediatrics and Child Health
1 shared papers, latest 2024
Ana Konvalinka
Medicine/Nephrology
1 shared papers, latest 2024
Sonya MacParland
Department of Laboratory Medicine and Pathobiology
1 shared papers, latest 2024
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