Faculty profile
Amra Saric
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Latest papers
Lipid scrambling via TMEM16F mediates the formation and release of extracellular vesicles.
Molecular biology of the cell · 2026
Angiogenesis is limited by LIC1-mediated lysosomal trafficking.
Angiogenesis · 2024
Pressure sensing of lysosomes enables control of TFEB responses in macrophages.
Nature cell biology · 2024
Latest funding
- $1,067,175
Sorting Nexins as Mediators of Lipid Traffic for Autophagosome Biogenesis
CIHR · 2025 · Nominated PI
- $1,555,245
Modafinil and Exercise for Post Stroke Fatigue (MODEX)
CIHR · 2022 · Co-investigator
9 publications.
Lipid scrambling via TMEM16F mediates the formation and release of extracellular vesicles.
Le T, Collado MEP, Li YM, Saric A, Holthuis JCM, Grinstein S, Freeman SA
Angiogenesis is limited by LIC1-mediated lysosomal trafficking.
Johnson D, Colijn S, Richee J, Yano J, Burns M, Davis AE, Pham VN, Saric A, Jain A, Yin Y, Castranova D, Melani M, Fujita M, Grainger S, Bonifacino JS, Weinstein BM, Stratman AN
Pressure sensing of lysosomes enables control of TFEB responses in macrophages.
Cai R, Scott O, Ye G, Le T, Saran E, Kwon W, Inpanathan S, Sayed BA, Botelho RJ, Saric A, Uderhardt S, Freeman SA
Regulation of angiogenesis by endocytic trafficking mediated by cytoplasmic dynein 1 light intermediate chain 1.
Johnson D, Colijn S, Richee J, Yano J, Burns M, Davis AE, Pham VN, Saric A, Jain A, Yin Y, Castranova D, Melani M, Fujita M, Grainger S, Bonifacino JS, Weinstein BM, Stratman AN
Measurement of Lysosome Positioning by Shell Analysis and Line Scan.
Williamson CD, Guardia CM, De Pace R, Bonifacino JS, Saric A
Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation.
Hipolito VEB, Diaz JA, Tandoc KV, Oertlin C, Ristau J, Chauhan N, Saric A, Mclaughlan S, Larsson O, Topisirovic I, Botelho RJ
Chemokine Signaling Enhances CD36 Responsiveness toward Oxidized Low-Density Lipoproteins and Accelerates Foam Cell Formation.
Wong HS, Jaumouillé V, Freeman SA, Doodnauth SA, Schlam D, Canton J, Mukovozov IM, Saric A, Grinstein S, Robinson LA
mTOR controls lysosome tubulation and antigen presentation in macrophages and dendritic cells.
Saric A, Hipolito VE, Kay JG, Canton J, Antonescu CN, Botelho RJ
The Phosphoinositide-Gated Lysosomal Ca(2+) Channel, TRPML1, Is Required for Phagosome Maturation.
Dayam RM, Saric A, Shilliday RE, Botelho RJ
Sorting Nexins as Mediators of Lipid Traffic for Autophagosome Biogenesis
Principal investigators: Saric, Amra
Keywords: Autophagy; Lipid Transport; Membrane Contact Sites; Membrane Traffic; Organelles; Sorting Nexins
Modafinil and Exercise for Post Stroke Fatigue (MODEX)
Principal investigators: Bayley, Mark T; Eng, Janice J
Keywords: Exercise; Modafinil; Post Stroke Fatigue
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Neurosciences and Mental Health
- Cell Biology
- Lady Davis Institute for Medical Research
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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