Faculty profile
Arthur Mortha
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Read how they describe their research on their University of Toronto profile.
Latest papers
Goblet cells tune ILC2 activity through a gut-specific response checkpoint.
Science immunology · 2026 · senior author
The OCR369 cis-regulatory element controls gut peacekeeping cells.
Nature reviews. Immunology · 2026 · senior author
Sequential infection reprograms the immune landscape to shape future responses.
bioRxiv : the preprint server for biology · 2026
Latest funding
- $10,000
ILC6 - The 6th International Conference on Innate Lymphoid Cells
CIHR · 2025 · Nominated PI
- $1,101,600
A BMP2-driven program in fibroblasts instructs a niche for tissue-resident innate immune cells.
CIHR · 2025 · Nominated PI
- $822,376
Unravelling the Cellular and Immunologic Landscape of the Gut in Children with Primary Sclerosing Cholangitis at Single-Cell Resolution
CIHR · 2024 · Co-investigator
36 publications.
Goblet cells tune ILC2 activity through a gut-specific response checkpoint.
Burrows K, Ngai L, Tai SL, Chiaranunt P, Chen ELY, Kamath M, Zúñiga-Pflücker JC, Mortha A
The OCR369 cis-regulatory element controls gut peacekeeping cells.
Iakupova A, Mortha A
Sequential infection reprograms the immune landscape to shape future responses.
Guo M, Bouzaher YH, Abd-Rabbo D, Quevedo R, Elsaesser HJ, Xu W, Liu MYR, Izzati FN, Ciudad MT, Bianca M, Liu ZQ, de Oliveira JEM, Mortha A, Edgar LJ, McGaha TL, Reese TA, Brooks DG
GM-CSF regulates conserved ILC-like transcriptional states and myeloid cell signaling during ulceration in Crohn's disease.
Morrison JK, Sabic K, Maskey N, Talware S, Hsu NY, Chasteau C, Aslinger E, Herb J, Nayar S, Levantovsky R, Tastad C, Moss R, Soto A, Garcia-Barros M, Ntunzwenimana J, Glass M, Bao M, Zhang J, Gettler K, Han H, Stevens J, Tavares L, Thin TH, Khaitov S, Greenstein A, Brody R, Chu J, Mortha A, Cho JH, Chuang LS
A gut commensal protozoan determines respiratory disease outcomes by shaping pulmonary immunity
Burrows K, Ngai L, Chiaranunt P, Watt J, Popple S, Forde B, Denha S, Olyntho VM, Tai SL, Cao EY
Mitochondria in monocyte-derived cells promote tissue damage in multiple sclerosis.
Chen ZY, Mortha A
Amyloid-β-driven Alzheimer's disease reshapes the colonic immune system in mice.
Makhijani P, Valentino TR, Manwaring-Mueller M, Emani R, Mu WC, Aguirre CG, Tan CR, Rane A, Wilson KA, Kifle A, Chen N, Du H, Wu F, Ng JHY, Ambrose BD, Ashok Kumaar PV, Khan S, Winer S, Wang C, Mortha A, Furman D, Schilling B, Ellerby LM, Rojas OL, Andersen JK, Winer DA
Clock genes tune plasticity of group 3 innate lymphoid cells.
Tai SL, Ngai L, Mortha A
BRD4 acts as a pH sensor to tune inflammation.
Tai SL, Mortha A
Cell therapy with human IL-10-producing ILC2s limits xenogeneic graft-versus-host disease by inhibiting pathogenic T cell responses.
Reid KT, Colpitts SJ, Mathews JA, Santos Carreira A, Murphy JM, Borovsky DT, Jegatheeswaran S, Cui W, Alfaro Moya T, Sachewsky N, An J, Xia Y, Mortha A, Lee JB, Zhang L, Novitzky-Basso I, Mattsson J, Crome SQ
ILC6 - The 6th International Conference on Innate Lymphoid Cells
Principal investigators: Mortha, Arthur
Keywords: Immunology
A BMP2-driven program in fibroblasts instructs a niche for tissue-resident innate immune cells.
Principal investigators: Mortha, Arthur
Keywords: Mucosal Immunology
Unravelling the Cellular and Immunologic Landscape of the Gut in Children with Primary Sclerosing Cholangitis at Single-Cell Resolution
Principal investigators: Ricciuto, Amanda; Bader, Gary D; MacParland, Sonya
Keywords: Colitis; Inflammatory Bowel Disease (Ibd); Machine Learning; Paediatric; Primary Sclerosing Cholangitis (Psc); Screening; Single-Cell Transcriptomics
Protist:microbiome dynamics in the mammalian gut
Principal investigators: Parkinson, John
Keywords: Computational Biology; Global Health; Metabolic Modeling; Metagenomics; Microbiome; Pathobionts; Protist:Microbiome Interactions; Protozoa; Single Cell Genomics; Tritrichomonas
Training Program in Engineering Approaches to Preserve and Rejuvenate Organs (TENPRO)
Principal investigators: Sefton, Michael MV
Keywords: bioengineering; biomedical devices; biotechnology; cell therapy; commercialization; gene editing; manufacturing; regeneration; tissue repair; translation
Protist:microbiome dynamics in the mammalian gut
Principal investigators: Parkinson, John
Keywords: Computational Biology; Global Health; Metabolic Modeling; Metagenomics; Microbiome; Pathobionts; Protist:Microbiome Interactions; Protozoa; Single Cell Genomics; Tritrichomonas
Protozoan gut commensal microbes regulate host immunity and health.
Principal investigators: Mortha, Arthur
Keywords: Adaptive Immune Cells; B Cells; Host-Microbiota Interactions; Iga Antibodies; Innate Immune Cells; Protozoa
Canada Research Chair - Tier 2
Principal investigators: Mortha, Arthur
Keywords: Crc
Gut microbiota and the etiology of colon cancer
Principal investigators: Martin, Alberto
Keywords: Adenomatous Polyposis Coli; Colon Cancer; Diet And Cancer; Dna Repair; Gut Microbiota; Inflammatory Bowel Disease; Mismatch Repair Deficiency; Pathobionts
Environmental control of gene expression in commensal protozoa
Principal investigators: Mortha, Arthur
Keywords: trans-kingdom interactions; microbe-microbe interactions; protozoa; bacteria; microbial communities; transcriptomics; intestinal microflora; microbiota; mucosal immunology; homeostasis
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Jonas Mattsson and Tommy Alfaro Moya: 18 shared papers
- John Parkinson and Arthur Mortha: 2 shared papers
- Josh Koenig and Jun Liu: 1 shared paper
- Josh Koenig and Clinton Robbins: 1 shared paper
- Josh Koenig and Slava Epelman: 1 shared paper
- Josh Koenig and Arthur Mortha: 1 shared paper
- Jun Liu and Arthur Mortha: 1 shared paper
- Thierry Mallevaey and Slava Epelman: 1 shared paper
- Thierry Mallevaey and Arthur Mortha: 1 shared paper
- Clinton Robbins and Slava Epelman: 1 shared paper
- Clinton Robbins and Arthur Mortha: 1 shared paper
- Clinton Robbins and Valeria Ramaglia: 1 shared paper
- Li Zhang and Arthur Mortha: 1 shared paper
- Li Zhang and Jonas Mattsson: 1 shared paper
- Li Zhang and Tommy Alfaro Moya: 1 shared paper
- Slava Epelman and Arthur Mortha: 1 shared paper
- Arthur Mortha and Jonas Mattsson: 1 shared paper
- Arthur Mortha and Chao Wang: 1 shared paper
- Arthur Mortha and Valeria Ramaglia: 1 shared paper
- Arthur Mortha and Kyle Burrows: 1 shared paper
- Arthur Mortha and Tommy Alfaro Moya: 1 shared paper
- Arthur Mortha and Kevan Jacobson: 1 shared paper
- Department of Immunology
- Department of Medicine
- Biochemistry (St. George Campus)
- Department of Molecular Genetics
- Department of Pediatrics
- Department of Laboratory Medicine & Pathobiology
- Cardiology
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
John Parkinson
Biochemistry (St. George Campus)
2 shared papers, latest 2024
Kyle Burrows
Faculty
1 shared papers, latest 2026
Valeria Ramaglia
Faculty
1 shared papers, latest 2019
Tommy Alfaro Moya
Department of Medicine
1 shared papers, latest 2025
Chao Wang
Faculty
1 shared papers, latest 2025
Jonas Mattsson
Faculty
1 shared papers, latest 2025
Kevan Jacobson
Department of Pediatrics
1 shared papers, latest 2021
Jun Liu
Department of Molecular Genetics
1 shared papers, latest 2025
Josh Koenig
Department of Medicine
1 shared papers, latest 2025
Clinton Robbins
Faculty
1 shared papers, latest 2019
Li Zhang
Department of Laboratory Medicine & Pathobiology
1 shared papers, latest 2025
Slava Epelman
Cardiology
1 shared papers, latest 2023
Thierry Mallevaey
Department of Immunology
1 shared papers, latest 2023
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Profile data last refreshed on September 26, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.