Faculty profile

Chao Wang

ResearcherUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses may be missing. Find their university profile.

Chao Wang

Researcher

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
16 publications in the last five years, latest in 2026.
Senior (last) author on 2 recent papers, a sign of leading a research group.
Principal investigator on 2 research grants (2 CIHR), most recently in 2023.
Supervised 1 trainee who won CIHR awards, most recently in 2022.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Gamma-Delta T Cells Il-17 Meninge Stress Response Crc

Latest papers

ALY688 confers cardioprotection through macrophage TGFβ-mediated Treg/Th17 dependent multi-organ responses.
Pharmacological research · 2026
Peripheral monocyte ratio as a predictive biomarker for metastasis-directed therapy in prostate cancer: insights from an exploratory study.
BMC cancer · 2026
Plagl1 regulates the retinal progenitor cell to Müller glial cell transition.
PLoS genetics · 2026

All 29 publications

Latest funding

Cavitation enhanced chemoimmunotherapy in a triple negative breast cancer setting
CIHR · 2026 · Co-investigator
$761,176
Mechanisms of the sex-dependent effect of obesity in enhancing central nervous system autoimmunity
CIHR · 2026 · Co-investigator
$100,000
Focused ultrasound-mediated regenerative strategies for Alzheimer's disease
CIHR · 2024 · Co-investigator
$1,290,555

All 7 grants and awards

29 publications.

ALY688 confers cardioprotection through macrophage TGFβ-mediated Treg/Th17 dependent multi-organ responses.

Tang J, Sung HK, Lei Y, Teerawongsuwan S, Rungsiwiwut R, Wannaiampikul S, Chen J, Ridany I, Richard V, Borchers C, Kim Y, Cho SG, Coquant G, Corr SC, Wu J, Li RK, Wang C, Abdul-Sater AA, Sweeney G

Pharmacological research2026

DOI: 10.1016/j.phrs.2026.108359 PMID: 42521105

Peripheral monocyte ratio as a predictive biomarker for metastasis-directed therapy in prostate cancer: insights from an exploratory study.

Wang H, Rajagopal A, Cao K, Cimolai K, Petchiny TN, White SD, Cheung J, Loblaw A, Vesprini D, Leong H, Escueta V, Zhang L, Glicksman R, Cheung P, Wang C, Liu SK

BMC cancer2026

DOI: 10.1186/s12885-026-15854-1 PMID: 41888707

Plagl1 regulates the retinal progenitor cell to Müller glial cell transition.

Touahri Y, Pak A, David LA, Hanna J, Liu H, Xiao Y, Belfiore L, Ilnytskyy Y, van Oosten E, Tachibana N, Adnani L, Zhao J, Hoffman M, Dixit R, Zinyk D, Guidos CJ, Enzmann V, Bi P, Aubert I, Journot L, Kovalchuk I, Sauvé Y, Biernaskie J, Wang C, Okawa S, Del Sol A, Schuurmans C

PLoS genetics2026

DOI: 10.1371/journal.pgen.1012020 PMID: 41849358

CD5L:p40, a novel heterodimeric regulator of type 2 inflammation.

Wang C, Zaghouani S, Wallrapp A, Newcomer K, Greenfield E, Johnson JB, Barilla R, Pawlak M, Christian E, Burkett PR, Leabo M, Li P, Soto H, Chen RS, Monell C, Brown MH, Almo SC, Singer M, Regev A, Kuchroo VK

Journal of immunology (Baltimore, Md. : 1950)2026First author

DOI: 10.1093/jimmun/vkaf348 PMID: 41847855

ODC1 restricts meningeal B cell age-associated-like phenotype and function in multiple sclerosis: A human and experimental study.

Zurawski J, Tuncer A, Profant MR, Wang J, Green M, Park Y, Cao K, Paris S, Tauhid S, Jalkh Y, Quattrucci M, Chu R, Cao X, Kiss A, Chitnis T, Weiner H, Clish CB, Bakshi R, Wang C

Proceedings of the National Academy of Sciences of the United States of America2026Senior author

DOI: 10.1073/pnas.2526147123 PMID: 41824499

MicroRNA-mediated neuronal detargeting alters astrocyte cell fate conversion trajectories in vivo.

Ghazale H, Parga Pazos M, Jung S, Cao K, Vasan L, Hickmott JW, Zhang L, Morshead CM, Wang C, Del Sol A, Schuurmans C

Communications biology2025

DOI: 10.1038/s42003-025-09169-3 PMID: 41350397

Amyloid-β-driven Alzheimer's disease reshapes the colonic immune system in mice.

Makhijani P, Valentino TR, Manwaring-Mueller M, Emani R, Mu WC, Aguirre CG, Tan CR, Rane A, Wilson KA, Kifle A, Chen N, Du H, Wu F, Ng JHY, Ambrose BD, Ashok Kumaar PV, Khan S, Winer S, Wang C, Mortha A, Furman D, Schilling B, Ellerby LM, Rojas OL, Andersen JK, Winer DA

Cell reports2025

DOI: 10.1016/j.celrep.2025.116109 PMID: 40885186

The glycolytic reaction PGAM restrains Th17 pathogenicity and Th17-dependent autoimmunity.

Wang C, Wagner A, Fessler J, DeTomaso D, Zaghouani S, Zhou Y, Pierce K, Sobel RA, Clish C, Yosef N, Kuchroo VK

Cell reports2025First author

DOI: 10.1016/j.celrep.2025.115799 PMID: 40482033

Examining the NEUROG2 lineage and associated gene expression in human cortical organoids.

Vasan L, Chinchalongporn V, Saleh F, Zinyk D, Ke C, Suresh H, Ghazale H, Belfiore L, Touahri Y, Oproescu AM, Patel S, Rozak M, Amemiya Y, Han S, Moffat A, Black SE, McLaurin J, Near J, Seth A, Goubran M, Reiner O, Gillis J, Wang C, Okawa S, Schuurmans C

Development (Cambridge, England)2025

DOI: 10.1242/dev.202703 PMID: 39680368

HEB Restrains Effector Gene Expression during Early CD8+ Memory Precursor T Cell Differentiation.

Leung JP, Haddadi S, Geuenich MJ, Tuncer A, Musiime V, Wang C, Zúñiga-Pflücker JC, Campbell KR, Anderson MK

Molecular and cellular biology2025

DOI: 10.1080/10985549.2025.2505730 PMID: 40418130

Cavitation enhanced chemoimmunotherapy in a triple negative breast cancer setting

Co-investigatorCIHR2026Project Grant

Principal investigators: Goertz, David E

Keywords: Breast Cancer; Cavitation; Chemotherapy; Focused Ultrasound; Immunotherapy; Microbubbles; Ultrasound

$761,176

Mechanisms of the sex-dependent effect of obesity in enhancing central nervous system autoimmunity

Co-investigatorCIHR2026Pr. Gr.- PA: Sex/Gender in Health Res.- Understanding sex/gender mech./processes

Principal investigators: Dunn, Shannon E

Keywords: Autoimmunity; Diet-Obesity; Experimental Autoimmune Encephalomyelitis; Mice; Multiple Sclerosis; T Cells; Type I Ifns

$100,000

Focused ultrasound-mediated regenerative strategies for Alzheimer's disease

Co-investigatorCIHR2024Project Grant

Principal investigators: Aubert, Isabelle

Keywords: Alzheimer Disease; Brain Plasticity; Focused Ultrasound; Gene Therapy; Neurogenesis; Non-Invasive Delivery To The Brain; Oligodendrogenesis; Regeneration

$1,290,555

Regulation of Stress Response by IL-17

Nominated PICIHR2023Project Grant

Principal investigators: Wang, Chao

Keywords: Gamma-Delta T Cells; Il-17; Meninge; Stress Response

$1,002,150

CD5 antigen-like as a regulator of neuroinflammation in a chronic stress-induced mouse model of Major Depressive Disorder

SupervisorCIHR2022Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Uthayakumar, Deeva

Keywords: Anti-Inflammatory Microglia; Crystallography; Depression And Mental Health; Flow Cytometry; Immunometabolism; Murine Behavioural Studies; Neuro-Immune Interactions; Sex Dimorphisms; Single-Cell Rna Sequencing

$105,000

Long COVID-19 on the human brain

Co-investigatorCIHR2021Op Grant: Emerging COVID-19 Research Gaps & Priorities - Post COVID-19 condition

Principal investigators: Graff-Guerrero, Ariel; Gerretsen, Philip

Keywords: Institute Of Neurosciences, Mental Health And Addiction; Post Covid-19 Condition; Subtopic 8: Understand Underlying Causes And Biological..

$932,475

Canada Research Chair - Tier 2

Nominated PICIHR2020Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Wang, Chao

Keywords: Crc

$600,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Chao Wang

Research

Latest papers

Latest funding

ALY688 confers cardioprotection through macrophage TGF&#x3b2;-mediated Treg/Th17 dependent multi-organ responses.

Peripheral monocyte ratio as a predictive biomarker for metastasis-directed therapy in prostate cancer: insights from an exploratory study.

Plagl1 regulates the retinal progenitor cell to M&#xfc;ller glial cell transition.

CD5L:p40, a novel heterodimeric regulator of type 2 inflammation.

ODC1 restricts meningeal B cell age-associated-like phenotype and function in multiple sclerosis: A human and experimental study.

MicroRNA-mediated neuronal detargeting alters astrocyte cell fate conversion trajectories in vivo.

Amyloid-&#x3b2;-driven Alzheimer's disease reshapes the colonic immune system in mice.

The glycolytic reaction PGAM restrains Th17 pathogenicity and Th17-dependent autoimmunity.

Examining the NEUROG2 lineage and associated gene expression in human cortical organoids.

HEB Restrains Effector Gene Expression during Early CD8+ Memory Precursor T Cell Differentiation.

Cavitation enhanced chemoimmunotherapy in a triple negative breast cancer setting

Mechanisms of the sex-dependent effect of obesity in enhancing central nervous system autoimmunity

Focused ultrasound-mediated regenerative strategies for Alzheimer's disease

Regulation of Stress Response by IL-17

CD5 antigen-like as a regulator of neuroinflammation in a chronic stress-induced mouse model of Major Depressive Disorder

Long COVID-19 on the human brain

Canada Research Chair - Tier 2

Frequent collaborators

Carol Schuurmans

Mario Ostrowski

Arun Seth

Carol Schuurmans

Jamie Near

Hon Leong

Hon Leong

Andrew Loblaw

Jean-Pierre Routy

Ren-Ke Li

Jean-Pierre Routy

Gary Sweeney

Isabelle Aubert

Samira Mubareka

Joanne McLaurin

Marjorie Brand

Michel Cayouette

Arthur Mortha

James Koropatnick

Maged Goubran

Monzur Murshed

Jianhong Wu

Lena Serghides

Jianhong Wu

ALY688 confers cardioprotection through macrophage TGFβ-mediated Treg/Th17 dependent multi-organ responses.

Plagl1 regulates the retinal progenitor cell to Müller glial cell transition.

Amyloid-β-driven Alzheimer's disease reshapes the colonic immune system in mice.