Faculty profile

Kumaraswamy Nanthakumar

ResearcherMedicine/CardiologyUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.

Kumaraswamy Nanthakumar

Researcher

Medicine/Cardiology

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
50 publications in the last five years, latest in 2026.
Senior (last) author on 30 recent papers, a sign of leading a research group.
Principal investigator on 13 research grants (13 CIHR), most recently in 2025.
Supervisor on 1 trainee award (1 CIHR), most recently in 2009.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

170

Publications

1,981

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Ventricular Tachycardia Ventricular Fibrillation Myocardium Mapping Cardiac Ablation Therapy Cardiac Electro-Anatomical Mapping Cardiac Repolarization Heart Rhythm Disorders

Latest papers

Buccal dantrolene for rapid systemic delivery: A novel antiarrhythmic approach.
Heart rhythm O2 · 2026 · senior author
Isochronal late activation mapping in ischemic scar VT: an independent validation using intraoperative mapping.
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
Principal Component-Referenced Multipolar Mapping to Localize an Arrhythmic Source From Various Depths of the Myocardium.
JACC. Clinical electrophysiology · 2026 · senior author

All 170 publications

Latest funding

Innovations in Repolarization Mapping Methodologies in Human Hearts
CIHR · 2025 · Nominated PI
$654,076
Cardioprotection against Adverse Side-Effects of Ibrutinib in Cancer Chemotherapy
CIHR · 2023 · Nominated PI
$100,000
Enabling novel cardiac therapies with pluripotent stem cells
SSHRC · 2022 · Co-investigator
$7,908,900

All 19 grants and awards

From the 150 most recent of 170 publications.

Buccal dantrolene for rapid systemic delivery: A novel antiarrhythmic approach.

Ouerd S, Chakraborty P, Massé S, Lai PFH, Chen EX, Amir E, deGruyther N, Nanthakumar K

Heart rhythm O22026Senior author

DOI: 10.1016/j.hroo.2025.11.012 PMID: 41732249

Isochronal late activation mapping in ischemic scar VT: an independent validation using intraoperative mapping.

Hayashi T, Muscat E, Rahimi M, Masse S, Veluppillai A, Nair KM, Ha A, Nanthakumar K, Downar E, Bhaskaran A

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2026

DOI: 10.1007/s10840-025-02138-0 PMID: 41085944

Principal Component-Referenced Multipolar Mapping to Localize an Arrhythmic Source From Various Depths of the Myocardium.

Denham N, Massé S, Abderrahman Y, Asta J, Lai P, Rodriguez H, Tsoref L, Nemaire M, Anderson R, Vigmond E, Nanthakumar K

JACC. Clinical electrophysiology2026Senior author

DOI: 10.1016/j.jacep.2025.10.016 PMID: 41348077

A multidimensional mapping array for assessment of myocardial activation using the electrotomographic mapping concept.

De Silva K, Massé S, Abderrahman Y, Subha T, Highsmith D, Ebrahimi B, Sheppard D, Botzer L, Asta J, Lai PFH, Denham N, Nanthakumar K

Heart rhythm2026Senior author

DOI: 10.1016/j.hrthm.2026.03.1902 PMID: 41881369

Psychological trauma and health-related quality of life following ventricular tachycardia ablation.

Bilanovic A, Irvine J, Porta-Sánchez A, King B, Angaran P, Dorian P, Baskaran A, Nayyar S, Ezzat V, Sawhney V, Hill A, Watkins S, Mariano Z, Surendran S, Koirala D, Downar E, Nanthakumar K

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2026Senior author

DOI: 10.1007/s10840-025-02211-8 PMID: 41739330

Electro-tomographic method to determine true north: Novel transmural mapping strategy for inappropriate sinus tachycardia ablation.

Hayashi T, De Silva K, Denham N, Korogyi A, Chakraborty P, Massé S, Nanthakumar K

Heart rhythm2026Senior author

DOI: 10.1016/j.hrthm.2025.08.009 PMID: 40789462

Human pluripotent stem cell-derived atrioventricular node-like pacemaker cells exhibit biological conduction bridge properties.

Lohbihler M, Lim AA, Massé S, Murareanu BM, Kwan M, Mourad O, Mastikhina O, Elbatarny M, Sarao R, Qiang B, Dhahri W, Chang ML, Xu ALY, Suthiwanich K, Chen M, Mazine A, Khattak S, Nunes SS, Nanthakumar K, Laflamme MA, Protze S

Cell stem cell2026

DOI: 10.1016/j.stem.2026.02.012 PMID: 41875893

Microvolt Activation Alternans Identifies Conduction Velocity Heterogeneity and the Entrance Site of Ischemic Ventricular Tachycardia.

Denham NC, Suszko AM, Nemaire M, Bhaskaran A, Massé S, Nanthakumar K, Haïssaguerre M, Downar E, Vigmond E, Chauhan VS

JACC. Clinical electrophysiology2025

DOI: 10.1016/j.jacep.2025.02.014 PMID: 40243961

The Accuracy of Cardiac Surface Conduction Velocity Measurements.

Vigmond EJ, Massé S, Roney CH, Bayer JD, Nanthakumar K

JACC. Clinical electrophysiology2025Senior author

DOI: 10.1016/j.jacep.2024.11.004 PMID: 39818672

Isochronal Apparent Dispersion at Early Activation Sites Accurately Identifies Outflow Tract Ventricular Ectopy Sites.

Anderson RD, Masse S, Hawson J, Lee G, Prabhu M, Bhaskaran A, Ha ACT, Nair K, Chauhan V, Nanthakumar K

Heart, lung & circulation2025Senior author

DOI: 10.1016/j.hlc.2024.10.018 PMID: 39890583

Innovations in Repolarization Mapping Methodologies in Human Hearts

Nominated PICIHR2025Project Grant

Principal investigators: Nanthakumar, Kumaraswamy

Keywords: Cardiac Ablation Therapy; Cardiac Electro-Anatomical Mapping; Cardiac Repolarization; Heart Rhythm Disorders; Ventricular Fibrillation; Ventricular Tachycardia

$654,076

Cardioprotection against Adverse Side-Effects of Ibrutinib in Cancer Chemotherapy

Nominated PICIHR2023Project Grant

Principal investigators: Nanthakumar, Kumaraswamy

Keywords: Adenosine Monophosphate-Activated Protein Kinase; Bruton'S Tyrosine Kinase Inhibitors; Canagliflozin; Chemotherapy-Induced Cardiotoxicity; Empagliflozin; Ibrutinib; Intracellular Calcium Dynamics; Myocardial Metabolism; Onco-Arrhythmia; Ranolazine

$100,000

Enabling novel cardiac therapies with pluripotent stem cells

Co-investigatorSSHRC2022New Frontiers in Research Fund - Transformation

Principal investigators: Laflamme, Michael

Keywords: Cardiac regeneration; Pluripotent stem cells; Cell manufacturing; Heart failure; Synthetic biology; Tissue engineering; Biomedical imaging; 3D bioprinting; Mathematical modeling; Health technology assessment; Bioethics

$7,908,900

Human Ventricular Tachycardia: Challenges in the Intramural Myocardium

Nominated PICIHR2022Project Grant

Principal investigators: Nanthakumar, Kumaraswamy

Keywords: Arrhythmias; Intramural Myocardial Electrophysiology; Myocardium; Radiofrequency Ablation; Ventricular Tachycardia

$495,720

Augmented Renal Denervation for the Prevention of Cardiac Arrhythmias.

Nominated PICIHR2016Project Grant

Principal investigators: Nanthakumar, Kumaraswamy

Keywords: Cardiac Arrhythmia; Cardiac Electrophysiology; Myocardial Infarction; Renal Sympathetic Denervation

$600,524

Platform technology for maturation of human stem cell derived cardiomyocytes and cardiotoxicity screening

Co-investigatorNSERC2016Collaborative Health Research Projects

Principal investigators: Radisic, Milica

$149,789

BaSIS Risk Score for Primary Prevention Implantable Cardioverter Defibrillators

Co-investigatorCIHR2016Project Grant

Principal investigators: Lee, Douglas S

Keywords: Health Services Research; Heart Failure; Implantable Cardioverter Defibrillator; Left Ventricular Dysfunction; Outcomes Research; Risk Benefit; Risk Prediction; Sudden Cardiac Death; Survival

$592,488

Platform technology for maturation of human stem cell derived cardiomyocytes and cardiotoxicity screening

Principal investigatorCIHR2015Collaborative Health Research Projects (NSERC partnered)

Principal investigators: Radisic, Milica; Nanthakumar, Kumaraswamy

Keywords: Cardiotoxicity; Contraction; Drug; Heart; Mapping; Microfabrication; Myocardium; Pluripotent Stem Cells; Tissue; Tissue Engineering

$149,788

Translational Studies of RyR2 Modulation for Human Ventricular Fibrillation

Nominated PICIHR2015Operating Grant

Principal investigators: Nanthakumar, Kumaraswamy

Keywords: Sudden Cardiac Death; Ventricular Fibrillation

$625,834

Mitochondrial Redox State Modulation to Improve Human Cardiac Arrest Outcome.

Nominated PICIHR2013Operating Grant

Principal investigators: Nanthakumar, Kumaraswamy

Keywords: Cardiac Arrest

$273,389

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Kumaraswamy Nanthakumar

Research

Latest papers

Latest funding

Buccal dantrolene for rapid systemic delivery: A novel antiarrhythmic approach.

Isochronal late activation mapping in ischemic scar VT: an independent validation using intraoperative mapping.

Principal Component-Referenced Multipolar Mapping to Localize an Arrhythmic Source From Various Depths of the Myocardium.

A multidimensional mapping array for assessment of myocardial activation using the electrotomographic mapping concept.

Psychological trauma and health-related quality of life following ventricular tachycardia ablation.

Electro-tomographic method to determine true north: Novel transmural mapping strategy for inappropriate sinus tachycardia ablation.

Human pluripotent stem cell-derived atrioventricular node-like pacemaker cells exhibit biological conduction bridge properties.

Microvolt Activation Alternans Identifies Conduction Velocity Heterogeneity and the Entrance Site of Ischemic Ventricular Tachycardia.

The Accuracy of Cardiac Surface Conduction Velocity Measurements.

Isochronal Apparent Dispersion at Early Activation Sites Accurately Identifies Outflow Tract Ventricular Ectopy Sites.

Enabling novel cardiac therapies with pluripotent stem cells

Platform technology for maturation of human stem cell derived cardiomyocytes and cardiotoxicity screening

Frequent collaborators

Paul Dorian

Karthikeyan Umapathy

Milica Radisic

Andrew Ha

Vijay Chauhan

Paaladinesh Thavendiranathan

Sheila Riazi

Filio Billia

Gordon Keller

Paul Khairy

Bruce Urch

Boyang Zhang

Stanley Nattel

Peter Backx

Mansoor Husain

Boyang Zhang

Peter Backx

Heather Ross

Ren-Ke Li

Yu Sun

David Birnie

Stephanie Protze

Eitan Amir

Jeff Healey

Andrew Ramadeen

Mihaela Pop

John Floras

Michael Laflamme

Zachary Laksman

Graham Wright

Jun Liu

Nigel Tan

Darryl Leong

David Jaffray