Faculty profile

Gaspard Montandon

ResearcherMedicineUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses may be missing. Find their university profile.

Gaspard Montandon

Researcher

Medicine

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
10 publications in the last five years, latest in 2026.
Senior (last) author on 6 recent papers, a sign of leading a research group.
Principal investigator on 4 research grants (4 CIHR), most recently in 2023.
Supervised 4 trainees who won CIHR awards, most recently in 2022.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Respiratory Depression Opioids Breathing Neuroscience Opioid Analgesia Opioid Overdose Pain Respiratory Physiology

Latest papers

Cholinergic premotor modulation of hypoglossal motor activity identified from combined "opto-dialysis" in vivo.
Journal of neurophysiology · 2026
Breath taking fentanyl: how ether-à-go-go potassium channels freeze your breath.
The Journal of physiology · 2026 · first author
Mu-opioid receptors in tachykinin-1-positive cells mediate the respiratory and antinociceptive effects of the opioid fentanyl.
British journal of pharmacology · 2025 · senior author

All 29 publications

Latest funding

Context-specific effects of opioid overdose in mice
CIHR · 2024 · Co-investigator
$1,243,126
Unravelling the neural basis of breathing, respiratory depression, and analgesia by opioid drugs.
CIHR · 2023 · Nominated PI
$891,226
Inhibitory GABAergic neurotransmission in the brainstem regulates respiratory rhythm and opioid-induced respiratory depression
CIHR · 2022 · Supervisor
$105,000

All 10 grants and awards

29 publications.

Cholinergic premotor modulation of hypoglossal motor activity identified from combined "opto-dialysis" in vivo.

Ladha RA, da Silveira Scarpellini C, Liu WY, Liu H, Grace KP, Montandon G, Horner RL

Journal of neurophysiology2026

DOI: 10.1152/jn.00634.2024 PMID: 42485048

Breath taking fentanyl: how ether-à-go-go potassium channels freeze your breath.

Montandon G

The Journal of physiology2026First author

DOI: 10.1113/jp290161 PMID: 41235906

Mu-opioid receptors in tachykinin-1-positive cells mediate the respiratory and antinociceptive effects of the opioid fentanyl.

Furdui A, da Silveira Scarpellini C, Montandon G

British journal of pharmacology2025Senior author

DOI: 10.1111/bph.17369 PMID: 39506356

Anatomical distribution of µ-opioid receptors, neurokinin-1 receptors, and vesicular glutamate transporter 2 in the mouse brainstem respiratory network.

Furdui A, da Silveira Scarpellini C, Montandon G

Journal of neurophysiology2024Senior author

DOI: 10.1152/jn.00478.2023 PMID: 38748514

Editorial: Opioid-induced respiratory depression: neural circuits and cellular pathways.

Stucke AG, Levitt ES, Montandon G

Frontiers in physiology2023Senior author

DOI: 10.3389/fphys.2023.1348910 PMID: 38179143

Maturational effect of leptin on CO2 chemosensitivity in newborn rats.

Tamir-Hostovsky L, Ivanovska J, Parajón E, Patel R, Wang H, Biouss G, Ivanovski N, Belik J, Pierro A, Montandon G, Gauda EB

Pediatric research2023

DOI: 10.1038/s41390-023-02604-3 PMID: 37185965

Medullary tachykinin precursor 1 neurons promote rhythmic breathing.

Rousseau JP, Furdui A, Silveira Scarpellini CD, Horner RL, Montandon G

eLife2023Senior author

DOI: 10.7554/elife.85575 PMID: 37458576

Fentanyl-Induced Respiratory Depression and Locomotor Hyperactivity Are Mediated by μ-Opioid Receptors Expressed in Somatostatin-Negative Neurons.

Furdui A, da Silveira Scarpellini C, Montandon G

eNeuro2023Senior author

DOI: 10.1523/eneuro.0035-23.2023 PMID: 37364996

βγ G-proteins, but not regulators of G-protein signaling 4, modulate opioid-induced respiratory rate depression.

Danaf J, da Silveira Scarpellini C, Montandon G

Frontiers in physiology2023Senior author

DOI: 10.3389/fphys.2023.1043581 PMID: 37089428

The pathophysiology of opioid-induced respiratory depression.

Montandon G

Handbook of clinical neurology2022First author

DOI: 10.1016/b978-0-323-91534-2.00003-5 PMID: 35965031

Context-specific effects of opioid overdose in mice

Co-investigatorCIHR2024Project Grant

Principal investigators: Josselyn, Sheena A

Keywords: Brain Circuits; Breathing; Chemogenetics; Engrams; Memory; Mouse; Opiates; Optogenetics

$1,243,126

Unravelling the neural basis of breathing, respiratory depression, and analgesia by opioid drugs.

Nominated PICIHR2023Project Grant

Principal investigators: Montandon, Gaspard

Keywords: Analgesia; Brain; Breathing; Neuroscience; Opioids; Optogenetics; Respiratory Depression; Sedation

$891,226

Inhibitory GABAergic neurotransmission in the brainstem regulates respiratory rhythm and opioid-induced respiratory depression

SupervisorCIHR2022Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Baker, Kayla

Keywords: Brainstem; Fentanyl; Gaba; Glutamate; Morphine; Opioids; Optogenetics; Plethysmography; Prebotzinger Complex; Respiration

$105,000

Identification of new molecular targets to treat opioid overdose and addiction using targeted mutagenesis in larval zebrafish

SupervisorCIHR2021CIHR Fellowship

Principal investigators: Facciol, Amanda J

Keywords: Addiction; Drug Discovery; Mutagenesis; Neuroscience; Opioid; Overdose; Zebrafish

$135,000

The effect of L-Citrulline administration on the inflammatory signature in the central respiratory network induced by primary lung inflammation during early development

Co-investigatorSSHRC2021New Frontiers in Research Fund - Exploration

Principal investigators: Gauda, Estelle

Keywords: Bronchopulmonary dysplasia Developmental Biology Prematurity Oxidative injury Inflammation Lung Development Control of Breathing

$249,846

The zebrafish, an emerging animal model to identify safe opioid pain therapies

SupervisorCIHR2019Travel Awards - Institute Community Support

Principal investigators: Zaig, Shenhab

Keywords: Ics Travel Awards

$1,000

Mechanisms of opioid-induced respiratory depression

Nominated PICIHR2019Early Career Investigator Awards - Circulatory and Respiratory Health

Principal investigators: Montandon, Gaspard

Keywords: Opioid Analgesia; Opioid Overdose; Opioids; Pain; Respiratory Depression; Respiratory Physiology

$345,000

Mechanisms of opioid-induced respiratory depression

Nominated PICIHR2019Early Career Investigator Awards

Principal investigators: Montandon, Gaspard

Keywords: Opioid Analgesia; Opioid Overdose; Opioids; Pain; Respiratory Depression; Respiratory Physiology

$345,000

Cell populations regulating opioid-induced respiratory depression in sleep-wake states

SupervisorCIHR2018Fellowship - PA - Sleep and Circadian Rhythms (Biomedical)

Principal investigators: Rousseau, Jean-Philippe

Keywords: Analgesia; Brainstem Cell Populations; Central Nervous System; Control Of Breathing; Electrocorticals Recordings; Opioids; Optogenetics; Prebötzinger Complex; Respiratory Depression; Whole Body Respiratory Recordings

$112,500

Neural and Molecular Basis of Opioid-Induced Respiratory Depression

Nominated PICIHR2018Project Grant

Principal investigators: Montandon, Gaspard

Keywords: Analgesics; Breathing; Neuroscience; Opioid; Respiration; Respiratory Depression

$745,876

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Gaspard Montandon

Research

Latest papers

Latest funding

Cholinergic premotor modulation of hypoglossal motor activity identified from combined "opto-dialysis" in vivo.

Breath taking fentanyl: how ether-à-go-go potassium channels freeze your breath.

Mu-opioid receptors in tachykinin-1-positive cells mediate the respiratory and antinociceptive effects of the opioid fentanyl.

Anatomical distribution of µ-opioid receptors, neurokinin-1 receptors, and vesicular glutamate transporter 2 in the mouse brainstem respiratory network.

Editorial: Opioid-induced respiratory depression: neural circuits and cellular pathways.

Maturational effect of leptin on CO2 chemosensitivity in newborn rats.

Medullary tachykinin precursor 1 neurons promote rhythmic breathing.

Fentanyl-Induced Respiratory Depression and Locomotor Hyperactivity Are Mediated by μ-Opioid Receptors Expressed in Somatostatin-Negative Neurons.

βγ G-proteins, but not regulators of G-protein signaling 4, modulate opioid-induced respiratory rate depression.

The pathophysiology of opioid-induced respiratory depression.

Context-specific effects of opioid overdose in mice

Unravelling the neural basis of breathing, respiratory depression, and analgesia by opioid drugs.

Inhibitory GABAergic neurotransmission in the brainstem regulates respiratory rhythm and opioid-induced respiratory depression

Identification of new molecular targets to treat opioid overdose and addiction using targeted mutagenesis in larval zebrafish

The effect of L-Citrulline administration on the inflammatory signature in the central respiratory network induced by primary lung inflammation during early development

The zebrafish, an emerging animal model to identify safe opioid pain therapies

Mechanisms of opioid-induced respiratory depression

Mechanisms of opioid-induced respiratory depression

Cell populations regulating opioid-induced respiratory depression in sleep-wake states

Neural and Molecular Basis of Opioid-Induced Respiratory Depression

Frequent collaborators

Indra Narang

Tetyana Kendzerska

Frances Chung

James Duffin

Mahesh Nagappa

Jaques Belik

Agostino Pierro

Roman Genov

Fiona Campbell

Gaspard Montandon

Research

Latest papers

Latest funding

Cholinergic premotor modulation of hypoglossal motor activity identified from combined "opto-dialysis" in vivo.

Breath taking fentanyl: how ether-&#xe0;-go-go potassium channels freeze your breath.

Mu-opioid receptors in tachykinin-1-positive cells mediate the respiratory and antinociceptive effects of the opioid fentanyl.

Anatomical distribution of &#xb5;-opioid receptors, neurokinin-1 receptors, and vesicular glutamate transporter 2 in the mouse brainstem respiratory network.

Editorial: Opioid-induced respiratory depression: neural circuits and cellular pathways.

Maturational effect of leptin on CO2 chemosensitivity in newborn rats.

Medullary tachykinin precursor 1 neurons promote rhythmic breathing.

Fentanyl-Induced Respiratory Depression and Locomotor Hyperactivity Are Mediated by &#x3bc;-Opioid Receptors Expressed in Somatostatin-Negative Neurons.

&#x3b2;&#x3b3; G-proteins, but not regulators of G-protein signaling 4, modulate opioid-induced respiratory rate depression.

The pathophysiology of opioid-induced respiratory depression.

The effect of L-Citrulline administration on the inflammatory signature in the central respiratory network induced by primary lung inflammation during early development

Frequent collaborators

Indra Narang

Tetyana Kendzerska

Frances Chung

James Duffin

Mahesh Nagappa

Jaques Belik

Agostino Pierro

Roman Genov

Fiona Campbell

Breath taking fentanyl: how ether-à-go-go potassium channels freeze your breath.

Anatomical distribution of µ-opioid receptors, neurokinin-1 receptors, and vesicular glutamate transporter 2 in the mouse brainstem respiratory network.

Fentanyl-Induced Respiratory Depression and Locomotor Hyperactivity Are Mediated by μ-Opioid Receptors Expressed in Somatostatin-Negative Neurons.

βγ G-proteins, but not regulators of G-protein signaling 4, modulate opioid-induced respiratory rate depression.