Faculty profile

Giles Santyr

ResearcherPhysiology and Experimental MedicineUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.

Giles Santyr

Researcher

Physiology and Experimental Medicine

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
33 publications in the last five years, latest in 2026.
Senior (last) author on 15 recent papers, a sign of leading a research group.
Principal investigator on 5 research grants (3 CIHR, 2 NSERC), most recently in 2021.
Supervisor on 1 trainee award (1 CIHR), most recently in 2016.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

130

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Treatment Cystic Fibrosis Magnetic Resonance Imaging Asthma Free Breathing Hardware Lung Function Lung Structure

Latest papers

Editorial for "Benchmarking Hybrid CNN-Transformer Versus Pure Transformer Architectures for Accelerated Hyperpolarized 129Xe MRI Reconstruction".
Journal of magnetic resonance imaging : JMRI · 2026 · senior author
Comparison of Single-Breath and Multi-Breath Xe-MRI in the Longitudinal Assessment of Treatment in Children With Cystic Fibrosis.
Journal of magnetic resonance imaging : JMRI · 2026 · senior author
Automated Ultrashort Echo Time (UTE) MRI Low Signal Volume Analysis in Stable Pediatric Cystic Fibrosis and After Elexacaftor/Tezacaftor/Ivacaftor Therapy.
Journal of magnetic resonance imaging : JMRI · 2026 · senior author

All 50 publications

Latest funding

Development of multi-spectral hyperpolarized xenon MRI approaches for measuring cerebral hemodynamics and oxygenation in pediatric cerebrovascular disease
CIHR · 2024 · Co-investigator
$750,745
Advanced Fetal MRI Methods to Evaluate Prenatal Organ Development and Predict Postnatal Outcome in Congenital Heart Disease
CIHR · 2023 · Co-investigator
$1,048,050
Development of tracer gas lung MRI approaches using inert fluorinated gases
NSERC · 2021 · Principal investigator
$178,600

All 12 grants and awards

50 publications.

Editorial for "Benchmarking Hybrid CNN-Transformer Versus Pure Transformer Architectures for Accelerated Hyperpolarized 129Xe MRI Reconstruction".

Wood ML, Zanette B, Santyr G

Journal of magnetic resonance imaging : JMRI2026Senior author

DOI: 10.1002/jmri.70321 PMID: 41913252

Comparison of Single-Breath and Multi-Breath Xe-MRI in the Longitudinal Assessment of Treatment in Children With Cystic Fibrosis.

Alam FS, Munidasa S, Zanette B, Li D, Braganza S, Ratjen F, Santyr G

Journal of magnetic resonance imaging : JMRI2026Senior author

DOI: 10.1002/jmri.70242 PMID: 41609189

Automated Ultrashort Echo Time (UTE) MRI Low Signal Volume Analysis in Stable Pediatric Cystic Fibrosis and After Elexacaftor/Tezacaftor/Ivacaftor Therapy.

Zanette B, Bierbrier J, Munidasa S, Genkin D, Kirby M, Ratjen F, Santyr G

Journal of magnetic resonance imaging : JMRI2026Senior author

DOI: 10.1002/jmri.70333 PMID: 42080522

Utility of hyperpolarised xenon-129 magnetic resonance imaging in primary ciliary dyskinesia.

Wee WB, Zanette B, Munidasa S, Eddy RL, Rayment JH, To T, Ratjen F, Santyr G, Dell SD

ERJ open research2026

DOI: 10.1183/23120541.01105-2025 PMID: 41846691

Hyperpolarized 129Xe MRI in Pediatric Hematopoietic Stem Cell Transplant Recipients With and Without Bronchiolitis Obliterans Syndrome.

Zanette B, Alam FS, Ratjen F, Schechter T, Krueger J, Santyr G

Pediatric pulmonology2026Senior author

DOI: 10.1002/ppul.71818 PMID: 42689494

Lung mucus burden and treatment response assessed by MRI in the post-modulator era.

Matheson AM, Prather E, Willmering MM, Mata J, Santyr G, Ratjen FA, Kramer EL, Cleveland ZI, Woods JC

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society2026

DOI: 10.1016/j.jcf.2026.05.010 PMID: 42177100

A Systematic Review of the Variability of Ventilation Defect Percent Generated From Hyperpolarized Noble Gas Pulmonary Magnetic Resonance Imaging

Diamond VM, Bell LC, Bone JN, Driehuys B, Menchaca M, Santyr G, Svenningsen S, Thomen RP, Marshall H, Smith LJ

Journal of Magnetic Resonance Imaging20253 citationsOpen Access

DOI: 10.1002/jmri.29746 PMID: W4408026596

The Canadian Lung Outcomes in Users of Vaping Devices (CLOUD) Study: protocol for a prospective, observational cohort study

Burns P, Eddy RL, Li X, Yang J, Dhillon SS, Couillard S, Stickland MK, Guenette J, Svenningsen S, Tulloch T

BMJ Open2025

DOI: 10.1136/bmjopen-2025-100568

Application of the defect distribution index to functional lung MRI of pediatric cystic fibrosis lung disease and controls.

Kieninger E, Munidasa S, Curdy M, Streibel C, Zanette B, Woods J, Latzin P, Ratjen F, Santyr G

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society2025Senior author

DOI: 10.1016/j.jcf.2025.02.015 PMID: 40069051

Comparison of phase-resolved functional lung (PREFUL) and hyperpolarized 129Xe MRI for longitudinal monitoring of lung function in pediatric cystic fibrosis following elexacaftor/tezacaftor/ivacaftor.

Munidasa S, Alam F, Zanette B, Li D, Wee W, Braganza S, Woods J, Ratjen F, Santyr G

Pediatric radiology2025Senior author

DOI: 10.1007/s00247-025-06390-4 PMID: 40938435

Development of multi-spectral hyperpolarized xenon MRI approaches for measuring cerebral hemodynamics and oxygenation in pediatric cerebrovascular disease

Co-investigatorCIHR2024Project Grant

Principal investigators: Kassner, Andrea; Zanette, Brandon

Keywords: Asl; Bbb; Brain; Cbf; Gas Transfer; Hyperpolarized Xenon; Mri; Oxygenation; Perfusion; Sickle Cell Anemia

$750,745

Advanced Fetal MRI Methods to Evaluate Prenatal Organ Development and Predict Postnatal Outcome in Congenital Heart Disease

Co-investigatorCIHR2023Project Grant

Principal investigators: Macgowan, Christopher K

Keywords: Blood Flow; Blood Oxygenation; Congenital Heart Disease; Fetal Imaging; Magnetic Resonance Imaging; Medical Biophysics; Organ Development; Postnatal Outcomes; Pregnancy

$1,048,050

Development of tracer gas lung MRI approaches using inert fluorinated gases

Principal investigatorNSERC2021Alliance Grants

Principal investigators: Santyr, Giles

$178,600

The Canadian Respiratory Research Network Long COVID-19 Study

Co-investigatorCIHR2021Project Grant

Principal investigators: Gershon, Andrea S; Gupta, Samir; Kirby, Miranda A; Lavoie, Kim; Leung, Janice; Sin, Donald; Stickland, Michael K; To, Teresa

Keywords: Cohort Study; Complications; Covid-19 Sequelae; Imaging; Medical Care; Monitoring; Physiology; Respiratory Disease

$100,000

The Canadian Respiratory Research Network Long COVID-19 Study

Co-investigatorCIHR2021Op Grant: Emerging COVID-19 Research Gaps & Priorities - Post COVID-19 condition

Principal investigators: Gershon, Andrea S; Aaron, Shawn D; Gupta, Samir; Lavoie, Kim; Leung, Janice; Sin, Donald; Stickland, Michael K; To, Teresa

Keywords: Cohort Study; Covid-19; Covid-19 Sequelae; Respiratory Disease

$500,000

Magnetic Resonance Imaging Toolbox for Assessment of Lung Structure and Function in the Early Years of Life

Nominated PICIHR2020Project Grant

Principal investigators: Santyr, Giles E

Keywords: Asthma; Cystic Fibrosis; Free Breathing; Hardware; Lung Function; Lung Structure; Mri; Preschoolers; Software; Treatment

$627,635

Novel Approaches for Magnetic Resonance Imaging of Neonatal Lung Structure and Function

Principal investigatorNSERC2019Discovery Grants Program - Individual

Principal investigators: Santyr, Giles

$300,000

Structural and Functional MRI in Preclinical Models of Bronchopulmonary Dysplasia

Nominated PICIHR2016Project Grant

Principal investigators: Santyr, Giles E

Keywords: Animal Models; Bronchopulmonary Dysplasia; Diagnosis; Function; Hyperpolarized Xenon Gas; Lung; Magnetic Resonance Imaging; Pediatrics; Preterm Birth; Treatment

$485,775

Structural and Functional MRI Assessment of Treatment Response in Early Cystic Fibrosis Lung Disease

Nominated PICIHR2016Project Grant

Principal investigators: Santyr, Giles E; Ratjen, Felix

Keywords: Cftr Modulator Therapy; Cystic Fibrosis; Hyperpolarized 129xe; Lung Clearance Index; Magnetic Resonance Imaging; Multiple Breath Washout; Paediatric; Pulmonary Function Test

$619,650

Assessment of Cystic Fibrosis using Multiple Breath Washout Hyperpolarized 129Xe Magnetic Resonance Imaging

SupervisorCIHR2016CIHR Fellowship

Principal investigators: Couch, Marcus J

Keywords: Cystic Fibrosis; Hyperpolarized 129xe; Lung Clearance Index; Magnetic Resonance Imaging; Multiple Breath Washout; Ventilation

$135,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Giles Santyr

Research

Latest papers

Latest funding

Editorial for "Benchmarking Hybrid CNN-Transformer Versus Pure Transformer Architectures for Accelerated Hyperpolarized 129Xe MRI Reconstruction".

Comparison of Single-Breath and Multi-Breath Xe-MRI in the Longitudinal Assessment of Treatment in Children With Cystic Fibrosis.

Automated Ultrashort Echo Time (UTE) MRI Low Signal Volume Analysis in Stable Pediatric Cystic Fibrosis and After Elexacaftor/Tezacaftor/Ivacaftor Therapy.

Utility of hyperpolarised xenon-129 magnetic resonance imaging in primary ciliary dyskinesia.

Hyperpolarized 129Xe MRI in Pediatric Hematopoietic Stem Cell Transplant Recipients With and Without Bronchiolitis Obliterans Syndrome.

Lung mucus burden and treatment response assessed by MRI in the post-modulator era.

A Systematic Review of the Variability of Ventilation Defect Percent Generated From Hyperpolarized Noble Gas Pulmonary Magnetic Resonance Imaging

The Canadian Lung Outcomes in Users of Vaping Devices (CLOUD) Study: protocol for a prospective, observational cohort study

Application of the defect distribution index to functional lung MRI of pediatric cystic fibrosis lung disease and controls.

Comparison of phase-resolved functional lung (PREFUL) and hyperpolarized 129Xe MRI for longitudinal monitoring of lung function in pediatric cystic fibrosis following elexacaftor/tezacaftor/ivacaftor.

Development of tracer gas lung MRI approaches using inert fluorinated gases

Novel Approaches for Magnetic Resonance Imaging of Neonatal Lung Structure and Function

Frequent collaborators

Giles Santyr

Brandon Zanette

Felix Ratjen

Miranda Kirby

Miranda Kirby

Nicholas Barrowman

Grace Parraga

Sarah Svenningsen

Padmaja Subbarao

Teresa To

Andrea Kassner

Sanja Stanojevic

Padmaja Subbarao

Franco Momoli

Jacob Van Dyk

Andrew Hope

Hasina Samji

Hasina Samji

Nadya Ben Fadel

Matthew Fox

Shawn Aaron

Jaques Belik

Sherri Katz

Jonathon Leipsic

Peter Kim

Stephen Lam

Nades Palaniyar

Parameswaran Krishna Nair

Jordan Guenette

Terence Ho

Carmen Venegas Garrido

Melanie Kjarsgaard

Martin Post