This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses may be missing. Find their university profile.
Research
Latest papers
FASN inhibitor TVB-3166 prevents S-acylation of the spike protein of human coronaviruses.
Journal of lipid research · 2022
Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.
Journal of molecular biology · 2021
Trimeric HIV-1 gp140 fused with APRIL, BAFF, and CD40L on the mucosal gp140-specific antibody responses in mice.
Vaccine · 2020
Latest funding
- $1,357,876
Seasonal Coronaviruses: Receptor Binding, Immune Evasion and Cross-species Transmission
CIHR · 2026 · Nominated PI
- $100,000
Seasonal Coronaviruses: Receptor Binding, Immune Evasion and Cross-species Transmission
CIHR · 2025 · Nominated PI
- $100,000
Seasonal Coronaviruses: Receptor Binding, Immune Evasion and Cross-species Transmission
CIHR · 2024 · Nominated PI
3 publications.
FASN inhibitor TVB-3166 prevents S-acylation of the spike protein of human coronaviruses.
Mekhail K, Lee M, Sugiyama M, Astori A, St-Germain J, Latreille E, Khosraviani N, Wei K, Li Z, Rini J, Lee WL, Antonescu C, Raught B, Fairn GD
Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.
Miersch S, Li Z, Saberianfar R, Ustav M, Brett Case J, Blazer L, Chen C, Ye W, Pavlenco A, Gorelik M, Garcia Perez J, Subramania S, Singh S, Ploder L, Ganaie S, Chen RE, Leung DW, Pandolfi PP, Novelli G, Matusali G, Colavita F, Capobianchi MR, Jain S, Gupta JB, Amarasinghe GK, Diamond MS, Rini J, Sidhu SS
Trimeric HIV-1 gp140 fused with APRIL, BAFF, and CD40L on the mucosal gp140-specific antibody responses in mice.
Liu J, Clayton K, Gao W, Li Y, Zealey C, Budylowski P, Schwartz J, Yue FY, Bie Y, Rini J, Ostrowski M
Seasonal Coronaviruses: Receptor Binding, Immune Evasion and Cross-species Transmission
Principal investigators: Rini, James M
Keywords: Coronavirus; Cryo-Em; Neutralizing Antibodies; Viral Glycoproteins; Viral Receptors
Seasonal Coronaviruses: Receptor Binding, Immune Evasion and Cross-species Transmission
Principal investigators: Rini, James M
Keywords: Coronavirus; Cryo-Em; Neutralizing Antibodies; Viral Glycoproteins; Viral Receptors
Seasonal Coronaviruses: Receptor Binding, Immune Evasion and Cross-species Transmission
Principal investigators: Rini, James M
Keywords: Coronavirus; Cryo-Em; Neutralizing Antibodies; Viral Glycoproteins; Viral Receptors; X-Ray Crystallography
Investigating the carbohydrate binding fine-specificity of the human betacoronaviruses, HCoV-OC43 and HCoV-HKU1.
Principal investigators: Hassan, Zaky
Keywords: Carbohydrate Binding Coronaviruses; Glycobiology; Structural Biology
Automated cryo-plunger for preparation of vitrified samples for cryo-electron microscopy and cryo-electron tomography
Principal investigators: Lee, Jeffrey
COVID-19 Variant Network - Towards a comprehensive understanding of adaptive immunity to SARS-CoV-2
Principal investigators: Watts, Tania H; Ehrhardt, Rudolf A; Gommerman, Jennifer L; Martin, Alberto; Ostrowski, Mario A
Keywords: Antibody Dependent Enhancement; B Cell Reperotire; Correlates Of Protection; Covid19; Immune Memory; Neutralizing Antibody; Rna-Seq; Saliva Iga; T Cell Epitopes; Vaccines
Intranasal multivalent vaccines targeting COVID-19 variants of concern
Principal investigators: Liu, Jun
Keywords: Animals; Covid-19; Hd-Ad; Sars-Cov-2 Variants; Vaccine
COVID-19 Variant Supplement - Towards a comprehensive understanding of adaptive immunity to SARS-CoV-2
Principal investigators: Watts, Tania H; Ehrhardt, Rudolf A; Gommerman, Jennifer L; Martin, Alberto; Ostrowski, Mario A
Keywords: Antibody Dependent Enhancement; B Cell Reperotire; Correlates Of Protection; Covid19; Immune Memory; Neutralizing Antibody; Rna-Seq; Saliva Iga; T Cell Epitopes; Vaccines
COVID-19 Variant Supplement - Neutralizing Antibodies as SARS-CoV-2 Therapeutics
Principal investigators: Rini, James M
Keywords: Antibodies; Coronavirus; Covid-19; S-Protein; Sars-Cov-2; Therapeutic Antibodies
COVID-19 Variant Supplement - Development of safe and effective vaccines against COVID-19
Principal investigators: Liu, Jun
Keywords: Bcg; Coronavirus; Covid-19; Hd-Ad; Vaccines
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Molecular Genetics
- Research Institute
- Chemistry and Biology
- Medicine
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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