Faculty profile
Julie Forman-Kay
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Read how they describe their research on their University of Toronto profile.
Latest papers
Computational Methods to Investigate Intrinsically Disordered Proteins and their Complexes.
ArXiv · 2024
A curated rotamer library for common post-translational modifications of proteins.
Bioinformatics (Oxford, England) · 2024
Glutamate acts on acid-sensing ion channels to worsen ischaemic brain injury.
Nature · 2024
Latest funding
- $36,845
Ultraprecise photon detection for studying dynamic biological systems at the single molecule level
NSERC · 2025 · Co-investigator
- $47,000
Physicochemical interactions underlying phase separation involving disordered and folded protein elements
NSERC · 2024 · Principal investigator
- $1,013,626
Regulation of mRNA translation and deadenylation by phase separation of autism spectrum disorder-associated proteins
CIHR · 2023 · Nominated PI
9 publications.
Computational Methods to Investigate Intrinsically Disordered Proteins and their Complexes.
Liu ZH, Tsanai M, Zhang O, Forman-Kay J, Head-Gordon T
A curated rotamer library for common post-translational modifications of proteins.
Zhang O, Naik SA, Liu ZH, Forman-Kay J, Head-Gordon T
Glutamate acts on acid-sensing ion channels to worsen ischaemic brain injury.
Lai K, Pritišanac I, Liu ZQ, Liu HW, Gong LN, Li MX, Lu JF, Qi X, Xu TL, Forman-Kay J, Shi HB, Wang LY, Yin SK
A Curated Rotamer Library for Common Post-Translational Modifications of Proteins.
Zhang O, Naik SA, Liu ZH, Forman-Kay J, Head-Gordon T
Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain.
Yang YM, Arsenault J, Bah A, Krzeminski M, Fekete A, Chao OY, Pacey LK, Wang A, Forman-Kay J, Hampson DR, Wang LY
Development and characterization of synthetic antibodies binding to the cystic fibrosis conductance regulator.
Gakhal AK, Jensen TJ, Bozoky Z, Roldan A, Lukacs GL, Forman-Kay J, Riordan JR, Sidhu SS
What's in a name? Why these proteins are intrinsically disordered: Why these proteins are intrinsically disordered.
Dunker AK, Babu MM, Barbar E, Blackledge M, Bondos SE, Dosztányi Z, Dyson HJ, Forman-Kay J, Fuxreiter M, Gsponer J, Han KH, Jones DT, Longhi S, Metallo SJ, Nishikawa K, Nussinov R, Obradovic Z, Pappu RV, Rost B, Selenko P, Subramaniam V, Sussman JL, Tompa P, Uversky VN
The ubiquitin binding region of the Smurf HECT domain facilitates polyubiquitylation and binding of ubiquitylated substrates.
Ogunjimi AA, Wiesner S, Briant DJ, Varelas X, Sicheri F, Forman-Kay J, Wrana JL
19F NMR studies of solvent exposure and peptide binding to an SH3 domain.
Evanics F, Kitevski JL, Bezsonova I, Forman-Kay J, Prosser RS
Ultraprecise photon detection for studying dynamic biological systems at the single molecule level
Principal investigators: Gradinaru, Claudiu
Keywords: optical spectroscopy; time-resolved fluorescence; single-photon counting; single-molecule biophysics; protein dynamics; g protein coupled receptors; intrinsically disordered proteins; fluorescence microscopy; autocorrelation analysis; instrument design
Physicochemical interactions underlying phase separation involving disordered and folded protein elements
Principal investigators: Forman-Kay, Julie
Keywords: phase separation; intrinsically disordered protein regions; low complexity disordered regions; rna-binding proteins; biomolecular condensates; nmr; microscopy; rheology; physicochemical interactions; post-translational modifications
Regulation of mRNA translation and deadenylation by phase separation of autism spectrum disorder-associated proteins
Principal investigators: Forman-Kay, Julie D
Keywords: Autism Spectrum Disorder; Deadenylation; Enzyme Regulation; Fluorescence Resonance Energy Transfer; Intrinsically Disordered Protein Regions; Low Complexity Regions; Microscopy; Nuclear Magnetic Resonance; Phase Separation; Translation
Proposed Helium Recovery System for the UofT/Sick Kids Biomolecular NMR Facility
Principal investigators: Kay, Lewis
O-GlcNAc: specificity of modification and impact on protein condensation
Principal investigators: Forman-Kay, Julie D
Keywords: Cancer; Computational Methods; Enzyme Specificity; Mass Spectrometry; Neurodegenerative Disease; Nmr; Phase Separation; Post-Translational Modification
Intrinsically disordered regions in disease: from sequence to molecular properties to function
Principal investigators: Moses, Alan M
Keywords: Bioinformatics; Computational Biology; Disease Mechanisms; Intrinsically Disordered Regions; Proteins; Sequence Analysis
Canada Research Chair - Tier 1
Principal investigators: Forman-Kay, Julie D
Keywords: Crc
Investigating the impact of a CAPRIN1 condensate solvent on the conformational equilibrium and activity of the CNOT7 deadenylase
Principal investigators: Rangadurai, Atul Kaushik
Keywords: Biomolecular Condensates; Biomolecular Structure And Dynamics; Caprin1; Cnot7; Deadenylation; Enzyme Kinetics; Mrna Processing; Nuclear Magnetic Resonance Spectroscopy; Phase Separation
Investigating the structural, biophysical and biochemical properties of liquid-liquid phase separation in neurological disorders.
Principal investigators: Kim, Tae Hun
Keywords: Amyotrophic Lateral Sclerosis; Autism Spectrum Disorder; Fluorescence Microscope Imaging; Intrinsically Disordered Proteins; Liquid-Liquid Phase Separation; Nmr Spectroscopy
Functional Genomics of Neurodegenerative Diseases: Defining Molecular Pathogenesis and Targets for Biomarkers and Personalised Therapies
Principal investigators: ST GEORGE-HYSLOP, Peter H
Keywords: Alzheimer Disease; Biomarkers; Frontotemporal Lobar Degeneration; Functional Genetics Of Risk Genes; Intrinsically Disordered Phase Separating Proteins; Neurological Disorders; Therapeutic Targets
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Department of Biochemistry
- Neurosciences and Mental Health
- Lunenfeld-Tanenbaum Research Institute
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Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.