Faculty profile
Justin Nodwell
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Read how they describe their research on their University of Toronto profile.
Latest papers
The nematode Caenorhabditis elegans has a cationic amphiphilic drug (CAD) defense system.
PLoS biology · 2026
Transposon mutagenesis in bacterial natural product discovery.
Essays in biochemistry · 2026
A Cationic Amphiphilic Drug (CAD) Defense System in the Nematode Caenorhabditis elegans.
bioRxiv : the preprint server for biology · 2026
Latest funding
- $875,925
Determinants of antibiotic sensitivity and resistance in Gram positive bacteria
CIHR · 2022 · Nominated PI
- $150,000
Detectors for Serial Nanocrystal Electron Diffraction
NSERC · 2021 · Co-investigator
- $200,000
Development of CRISPR-Cas3 for genome editing tool in Streptomyces
NSERC · 2021 · Principal investigator
9 publications.
The nematode Caenorhabditis elegans has a cationic amphiphilic drug (CAD) defense system.
Tokmakjian L, Han D, Sihuta K, Aggarwal A, Pirhadi S, Wang Y, Burns AR, Cooke B, Ren S, Gavrielatos M, Liu J, Krause HM, Cummins CL, Nodwell J, Koes DR, Roy PJ
Transposon mutagenesis in bacterial natural product discovery.
Warsito MF, Nonthakaew N, Suppi M, Sharkey LKR, Nodwell J, Pidot SJ
A Cationic Amphiphilic Drug (CAD) Defense System in the Nematode Caenorhabditis elegans.
Tokmakjian L, Han D, Sihuta K, Aggarwal A, Pirhadi S, Wang Y, Burns AR, Cooke B, Ren S, Cummins CL, Nodwell J, Koes DR, Roy PJ
Addendum: A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase.
MacAlpine J, Daniel-Ivad M, Liu Z, Yano J, Revie NM, Todd RT, Stogios PJ, Sanchez H, O'Meara TR, Tompkins TA, Savchenko A, Selmecki A, Veri AO, Andes DR, Fidel PL, Robbins N, Nodwell J, Whitesell L, Cowen LE
Reply to: Lactobacillus species do not produce 1-acetyl-β-carboline.
MacAlpine J, Daniel-Ivad M, Atere D, Laflamme B, Robbins N, Navarre WW, Nodwell J, Whitesell L, Cowen LE
PRKN/parkin-mediated mitophagy is induced by the probiotics Saccharomyces boulardii and Lactococcus lactis.
Hawrysh PJ, Gao J, Tan S, Oh A, Nodwell J, Tompkins TA, McQuibban GA
A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase.
MacAlpine J, Daniel-Ivad M, Liu Z, Yano J, Revie NM, Todd RT, Stogios PJ, Sanchez H, O'Meara TR, Tompkins TA, Savchenko A, Selmecki A, Veri AO, Andes DR, Fidel PL, Robbins N, Nodwell J, Whitesell L, Cowen LE
Put a Bow on It: Knotted Antibiotics Take Center Stage.
Tan S, Moore G, Nodwell J
Streptomyces: a screening tool for bacterial cell division inhibitors.
Jani C, Tocheva EI, McAuley S, Craney A, Jensen GJ, Nodwell J
Determinants of antibiotic sensitivity and resistance in Gram positive bacteria
Principal investigators: Nodwell, Justin R
Keywords: Antibiotic Resistance; Antibiotics; Cell Wall Biosynthesis; Cell Wall Recycling; Staphylococcus Aureus; Stringent Response
Detectors for Serial Nanocrystal Electron Diffraction
Principal investigators: Ernst, Oliver
Development of CRISPR-Cas3 for genome editing tool in Streptomyces
Principal investigators: Nodwell, Justin
Evolutionarily optimized antimicrobial combinations and vesicle delivery systems from environmental actinomycetes
Principal investigators: Meyer, Kirsten J
Keywords: Antibiotic Combinations; Antibiotic Resistance; Drug Discovery; Extracellular Vesicles; Streptomyces Bacteria
The discovery of new antibiotics derived from inhibitors of sporulation
Principal investigators: Nodwell, Justin R
Keywords: Antibiotic Targets; Antibiotics; Enterococcus; Mrsa; Sporulation; Staphylococcus; Synthetic Molecules; Vre
A synthetic biology platform for the discovery and commercialization of natural products.
Principal investigators: Nodwell, Justin
Chemically-assisted discovery and investigation of antifungal drug leads
Principal investigators: Nodwell, Justin R
Keywords: Antifungal Drugs; Chemical Elicitors; Gene Expression; Signal Transduction; Streptomyces
Chemically-assisted discovery and investigation of antifungal drug leads
Principal investigators: Nodwell, Justin R
Keywords: Chemical Genetics; Drug Discovery; Saccharomyces Cereviciae; Small Molecule Purification; Streptomyces
Discovery of antibiotics by genetic manipulation of environmental microbes
Principal investigators: Nodwell, Justin R
Keywords: Antibiotic Discovery; Antibiotic Resistance; Inducible Promoters; Pathogenic Bacteria; Small Molecule Purification; Streptomyces
Understanding Antibiotic Resistance Through the Systematic Characterization of TetR-like Transcription Factors and Their Target Genes
Principal investigators: Nodwell, Justin R
Keywords: Antibiotic Resistance; High Throughput Screening; Protein/Dna Interactions; Protein/Ligand Interactions; Transcriptional Regulation
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Department of Biochemistry
- Microbiology and Infectious Diseases
- Chemical Engineering and Applied Chemistry
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.