Faculty profile
Karim Ladha
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Read how they describe their research on their University of Toronto profile.
Latest papers
Treating pain and trauma: A systematic review of non-randomized studies of psychotherapeutic approaches.
The journal of pain · 2026
Exclusion of psychiatric disorders in neuropathic pain research: a secondary analysis of 312 randomized controlled trials.
Pain · 2026 · senior author
Canadian real-world evidence: observational 24-week outcomes for health care practitioner authorized cannabis.
Canadian journal of pain = Revue canadienne de la douleur · 2026
Latest funding
- $730,576
The PLATform for INnovative Multicentre trials for comorbid chronic Pain and Depressive disorders (PLATINuM-PD)
CIHR · 2026 · Nominated PI
- $1,034,806
Ecstasy to Alleviate SEvere Chronic Neuropathic Pain (EASE Pain) - A Multi-centre Internal Pilot Randomized Controlled Trial
CIHR · 2025 · Co-investigator
- $100,000
Perioperative Vitamin C to reduce persistent pain after total knee arthroplasty (PROVISION): a multicentre randomized controlled trial
CIHR · 2025 · Co-investigator
38 publications.
Treating pain and trauma: A systematic review of non-randomized studies of psychotherapeutic approaches.
Bosma R, Curtis K, Williams C, Maxwell Slepian P, McCarthy M, Flynn M, Nella A, Kim A, Siegal R, Englesakis M, Ladha K, Di Renna T, Rosenbloom BN
Exclusion of psychiatric disorders in neuropathic pain research: a secondary analysis of 312 randomized controlled trials.
Arnold K, Al-Chalabi N, Mann M, Liu T, Husain MI, Rosenbloom BN, Ladha K
Canadian real-world evidence: observational 24-week outcomes for health care practitioner authorized cannabis.
Yang B, Diep C, Thaker S, Jackson T, Lakhani A, Landolt C, Pope E, Lara-Corrales I, Cortes Pradilla H, Yu HC, Mae Gabriel G, Darville R, Weisbrod K, Tingling K, Nandra K, Ganty P, Fiorellino J, Huang A, Tao L, Singh M, Chung Tai P, Carlen P, Ladha K, Clarke H
Electroconvulsive Therapy Variability Across Ontario 2007-2023: A Population Level Study: Variabilité de la thérapie électroconvulsive en Ontario de 2007 à 2023 : une étude au sein de la population.
Kaster TS, Campitelli MA, Babujee A, Huang A, Ladha K, Blumberger DM, Kurdyak P
Large language models and their current use in perioperative medicine: a scoping review protocol.
Mbadjeu Hondjeu AR, Zhao ZY, Newton L, Ajenkar A, Termos B, Shorr R, Ladha K, Wijeysundera D, McIsaac DI
Large language models in perioperative medicine-applications and future prospects: a narrative review.
Mbadjeu Hondjeu AR, Zhao ZY, Newton L, Ajenkar A, Hladkowicz E, Ladha K, Wijeysundera DN, McIsaac DI
Oral ketamine for acute postoperative analgesia (OKAPA) trial: A randomized controlled, single center pilot study.
Dinsmore M, Nijs K, Plitman E, Al Azazi E, Venkatraghavan L, Ladha K, Clarke H
A Prospective Cohort Study of Acute Pain and In-Hospital Opioid Consumption After Cardiac Surgery: Associations With Psychological and Medical Factors and Chronic Postsurgical Pain.
Pagé MG, Ganty P, Wong D, Rao V, Khan J, Ladha K, Hanlon J, Miles S, Katznelson R, Wijeysundera D, Katz J, Clarke H
Insurance-Related Disparities in Withdrawal of Life Support and Mortality After Spinal Cord Injury.
Shakil H, Essa A, Malhotra AK, Jaffe RH, Smith CW, Yuan EY, He Y, Badhiwala JH, Mathieu F, Sklar MC, Wijeysundera DN, Ladha K, Nathens AB, Wilson JR, Witiw CD
Traumatic Cervical Spinal Cord Injury and Income and Employment Status.
Jaffe RH, Coyte PC, Chan BC, Hancock-Howard RL, Malhotra AK, Ladha K, Wilson JR, Witiw CD
The PLATform for INnovative Multicentre trials for comorbid chronic Pain and Depressive disorders (PLATINuM-PD)
Principal investigators: Ladha, Karim; Clarke, Hance A; Goel, Akash; Husain, Muhammad I; Rosenblat, Joshua D; Rosenbloom, Brittany; Voineskos, Daphne; Zrenner, Christoph D
Keywords: Chronic Pain; Depression; Platform Trial
Ecstasy to Alleviate SEvere Chronic Neuropathic Pain (EASE Pain) - A Multi-centre Internal Pilot Randomized Controlled Trial
Principal investigators: Goel, Akash; Bosma, Rachael L; Khan, James S; McIsaac, Daniel I; Pritlove, Cheryl; Ritvo, Paul G; Rizvi, Sakina; Rosenblat, Joshua D; Wijeysundera, Duminda N
Keywords: Chronic Neuropathic Pain; Internal Pilot; Mdma 'Ecstasy'; Randomized Trial
Perioperative Vitamin C to reduce persistent pain after total knee arthroplasty (PROVISION): a multicentre randomized controlled trial
Principal investigators: Khan, James S; Chaudhry, Harman; Devereaux, Philip J; Gilron, Ian; Karkouti, Keyvan; Mundi, Raman; Wolfstadt, Jesse I
Keywords: Osteoarthritis; Pain; Persistent Pain; Prevention; Randomized Controlled Trial; Total Knee Arthroplasty; Vitamin C
Combining Ketamine with Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals with Treatment Resistant Depression and Borderline Personality Disorder: A Phase II Randomized, Midazolam-Controlled Clinical Trial
Principal investigators: Rosenblat, Joshua D; Burhan, Amer M; McMain, Shelley F
Keywords: Anesthesiology; Borderline Personality Disorder; Clinical Trial; Dialectical Behavioural Therapy; Ketamine; Major Depressive Disorder; Psychotherapy; Suicide; Treatment Resistant Depression
The Epidemiology of and Outcomes Associated with Comorbid Chronic Pain and Depression: Analysis of Canadian Longitudinal Study on Aging (CLSA) data
Principal investigators: Ladha, Karim; Clarke, Hance A
Keywords: Aging; Chronic Pain; Cognitive Decline; Comorbidity; Depression; Epidemiology; Prevalence
PATHway Forward: Strategic retreat for consensus on core outcomes and research planning for Pain and Trauma Healing
Principal investigators: Rosenbloom, Brittany; Bosma, Rachael L; Slepian, Peter M
Keywords: Chronic Pain; Psychological Treatment; Trauma
The Sustained Mood Improvement with Laughing Gas Exposure (SMILE) Trial
Principal investigators: Ladha, Karim; Husain, Muhammad I; Rosenblat, Joshua D
Keywords: Active Placebo; Depression Remission; Depression Response; Midazolam; Nitrous Oxide; Randomized Controlled Trial; Treatment Efficacy; Treatment-Resistant Depression
Optimizing Patient-centred outcomes Using opioid minimization Strategies (OPUS) Pilot Trial
Principal investigators: Verret, Michael; Fergusson, Dean A; Lalu, Manoj M; Turgeon, Alexis F
Keywords: Anesthesiology; Clinical Trial; Integrated Knowledge Translation; Opioid Minimization Strategies; Patient-Centred Outcomes; People With Lived Experience; Persistent Postoperative Opioid Use; Pragmatic; Recovery; Surgery
Intravenous Ketamine versus Personalized Accelerated Brain Stimulation in Treatment-Resistant Depression: A Pilot Randomized Feasibility Trial of Rapid-Acting Treatments (IKARE-TRD)
Principal investigators: Bhat, Venkat; Dunlop, Katharine A; Kcomt, Andrew; Ladha, Karim; Lou, Wen-Yi W; Swainson, Jennifer N; Zhang, Yanbo
Keywords: Brain Stimulation; Iv Ketamine; Pilot Trial; Randomized Controlled Trial; Treatment-Resistant Depression
Using an Artificial Intelligence Quality Indicator to optimize and evaluate delirium prevention efforts in hospitals
Principal investigators: Verma, Amol; Chignell, Mark H; Cohen, Eldan; Dolatabadi, Elham; Gopalkrishnan, Rahul; Liu, Barbara; McIlraith, Sheila; Razak, Fahad; Sheehan, Kathleen; Siddiqi, Arjumand; Thorpe, Kevin E; Trbovich, Patricia; Wong, Brian M; Wong, Camilla L
Keywords: Artificial Intelligence; Delirium; Implementation Science; Machine Learning; Patient Safety; Quality Improvement; Quality Indicators; Senior Friendly Hospital Care
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Department of Anesthesiology and Pain Medicine
- Anesthesiology and Pain Management
- Clinical Epidemiology
- Department of Surgery
- Thoracic Surgery
- Surgery
- Family Medicine
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Hance Clarke
Department of Anesthesiology and Pain Medicine
13 shared papers, latest 2026
Joel Katz
Faculty
6 shared papers, latest 2024
Akash Goel
Department of Anesthesiology and Pain Medicine
5 shared papers, latest 2024
James Khan
Anesthesiology and Pain Management
3 shared papers, latest 2024
Tania Di Renna
Faculty
3 shared papers, latest 2026
Rachael Bosma
Anesthesiology and Pain Management
2 shared papers, latest 2026
Francois Mathieu
Department of Surgery
2 shared papers, latest 2024
Daniel Santa Mina
Faculty
2 shared papers, latest 2021
Fahima Dossa
Clinical Epidemiology
2 shared papers, latest 2020
Duminda Wijeysundera
Department of Anesthesiology and Pain Medicine
2 shared papers, latest 2025
Marcelo Cypel
Thoracic Surgery
2 shared papers, latest 2024
Arjun Sahgal
Faculty
1 shared papers, latest 2024
Piotr Kozlowski
Electrical and Computer Engineering
1 shared papers, latest 2024
Christopher Witiw
Department of Surgery
1 shared papers, latest 2024
Susan Abbey
Department of Psychiatry
1 shared papers, latest 2019
Scott Duggan
Anesthesiology
1 shared papers, latest 2019
Andrew Howard
Epidemiology and Biostatistics
1 shared papers, latest 2024
Amanda Hall
Family Medicine
1 shared papers, latest 2024
Mandeep Singh
Department of Anesthesiology and Pain Medicine
1 shared papers, latest 2026
Stephen Choi
Department of Anesthesiology and Pain Medicine
1 shared papers, latest 2023
Maryse Fortin
Faculty
1 shared papers, latest 2024
Brian Kwon
Chemical Engineering and Applied Chemistry
1 shared papers, latest 2024
Eve Tsai
Surgery
1 shared papers, latest 2024
Anuj Bhatia
Department of Anesthesiology and Pain Medicine
1 shared papers, latest 2024
Luciana Macedo
Rehabilitation Science
1 shared papers, latest 2024
John Harlock
Surgery
1 shared papers, latest 2022
Daipayan Guha
Surgery
1 shared papers, latest 2024
Michael Fehlings
Department of Surgery
1 shared papers, latest 2024
Teresa To
Pediatrics
1 shared papers, latest 2024
Albert Yee
Surgery
1 shared papers, latest 2024
Monica Parry
Faculty
1 shared papers, latest 2021
Marjolaine Roy-Beaudry
Faculty
1 shared papers, latest 2024
Paul Karanicolas
Surgery
1 shared papers, latest 2023
Geoffrey Anderson
Institute of Health Policy, Management and Evaluation
1 shared papers, latest 2017
Anand Govindarajan
Faculty
1 shared papers, latest 2021
Andrea Furlan
Physiatry
1 shared papers, latest 2024
Andrea Doria
Diagnostic Imaging
1 shared papers, latest 2024
David Urbach
General Surgery
1 shared papers, latest 2020
Keyvan Karkouti
Department of Anesthesiology and Pain Medicine
1 shared papers, latest 2021
Brian Kwon
Faculty
1 shared papers, latest 2024
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Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.