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Research
Latest papers
ISHLT Consensus Statement on the Perioperative use of ECLS in Lung Transplantation: Part II: Intraoperative Considerations.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2026
The American Association for Thoracic Surgery (AATS) 2026 Expert Consensus Document: Guidelines for donor/recipient size-matching in lung transplantation.
The Journal of thoracic and cardiovascular surgery · 2026
MetaboSense: An Integrated Quantum Dot-Mediated Aptamer Assay and Modular Microfluidic Platform for Continuous In-Line Monitoring of Lung Metabolism During Ex Vivo Perfusion.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
Latest funding
- $6,000
Developing Lung Metastases in Animal Models for Novel Treatment
CIHR · 2026 · Supervisor
- $1,071,000
Whole organ gene editing for immunomodulation in lung transplantation
CIHR · 2025 · Co-investigator
- $120,000
Developing a Lipid Nanoparticle Platform for Endothelial Gene Delivery in Donor Lungs
CIHR · 2025 · Supervisor
From the 150 most recent of 326 publications.
ISHLT Consensus Statement on the Perioperative use of ECLS in Lung Transplantation: Part II: Intraoperative Considerations.
Martin AK, Mercier O, Fritz AV, Gelzinis TA, Hoetzenecker K, Lindstedt S, Marczin N, Wilkey BJ, Schecter M, Lyster H, Sanchez M, Walsh J, Morrissey O, Levvey B, Landry C, Saatee S, Kotecha S, Behr J, Kukreja J, Dellgren G, Fessler J, Bottiger B, Wille K, Dave K, Nasir BS, Gomez-De-Antonio D, Cypel M, Reed AK
The American Association for Thoracic Surgery (AATS) 2026 Expert Consensus Document: Guidelines for donor/recipient size-matching in lung transplantation.
Chang S, Geraci T, Stokes JW, Ahmad U, Catarino P, Ceulemans LJ, Cypel M, Halloran K, Haney J, Hartwig MG, Keshavjee S, Lemaitre P, Novoa N, Puri V, Sato M, Schaheen LW, Whitson B, Hoetzenecker K
MetaboSense: An Integrated Quantum Dot-Mediated Aptamer Assay and Modular Microfluidic Platform for Continuous In-Line Monitoring of Lung Metabolism During Ex Vivo Perfusion.
Srikant S, Keshavarz Motamed P, Borrillo T, Ronen L, Siebiger G, Garza G, Abouali H, Fattah MFA, Jaber I, Ban D, Cypel M, Liu M, Keshavjee S, Sage AT, Poudineh M
Impact of ex vivo lung perfusion evaluation on donation after circulatory death in lung transplantation.
Gil-Barturen M, Donahoe L, de Perrot M, Yasufuku K, Pierre A, Wakeam E, Waddell TK, Keshavjee S, Cypel M, Yeung JC
Outcomes of lung transplantation using TorEx ex-vivo lung perfusion.
Yamamoto H, Ali A, Siebiger G, Wakeam E, Donahoe L, Yeung JC, Pierre A, de Perrot M, Yasufuku K, Waddell TK, Keshavjee S, Cypel M
A Novel Approach for Resection of Centrally Located Metastatic Sarcoma to the Lung.
Nasralla A, Cypel M
ISHLT Consensus Statement on the Perioperative use of ECLS in Lung Transplantation: Part III: Postoperative Considerations.
Martin AK, Mercier O, Bottiger B, Cypel M, Fessler J, Gomez-De-Antonio D, Levvey B, Lyster H, Nasir B, Sanchez M, Wille K, Fritz AV, Gelzinis T, Hoetzenecker K, Dave K, Lindstedt S, Marczin N, Wilkey B, Schecter M, Walsh J, Morrissey O, Landry C, Saatee S, Kotecha S, Behr J, Kukreja J, Dellgren G, Reed AK
The need for clarity among the shadows: It is time to further refine the definition of primary graft dysfunction in lung transplant recipients.
Trindade AJ, Shaver CM, Demarest CT, Erasmus D, Keller BC, Langer NB, Kukreja J, Hays S, Schaheen L, Campo-Canaveral de la Cruz JL, Alonso-Moralejo R, Crowley Carrasco S, Laporta Hernandez R, Akbarshahi H, Lindstedt S, Chang SH, Angel LF, Benazzo A, Jaksch P, Sidhu A, Cypel M, Bacchetta M, Hoetzenecker K
Strategies to address donor organ shortages in lung transplantation.
Siebiger G, Cypel M
Itaconate supplementation leads to improvement in donor lung function after extended hypothermic preservation.
Siebiger G, Wang A, Yune J, Montagne J, Garza G, Lima T, Yamanashi K, Oliveira P, Gao FY, Zhang Y, Bellissimo CA, Aujla T, Beroncal E, Ali A, Goligher EC, Andreazza AC, Liu M, Keshavjee S, Cypel M
Developing Lung Metastases in Animal Models for Novel Treatment
Principal investigators: Powers, Kyle
Keywords: Cancer; Lung Metastases; N Vivo Lung Perfusion
Whole organ gene editing for immunomodulation in lung transplantation
Principal investigators: Keshavjee, Shaf; Juvet, Stephen C; Li, Bowen
Keywords: Acute Lung Injury; Chronic Rejection; Crispr; Ex Vivo Lung Perfusion; Gene Therapy; Interleukin (Il)-10; Lipid Nanoparticles; Lung Transplantation; Pre-Clinical Human Model; Whole Organ Gene Editing
Developing a Lipid Nanoparticle Platform for Endothelial Gene Delivery in Donor Lungs
Principal investigators: Yune, Jenny
Keywords: Acute Toxicity; Endothelial Modification; Ex-Vivo Lung Perfusion (Evlp); Gene Editing; Lipid Nanoparticles (Lnp); Lung Transplantation; Transfection Efficiency
Harnessing Lung's Ability to Hibernate: Strategies to Achieve Multiday Organ Preservation
Principal investigators: Cypel, Marcelo; Kluger, Ronald H; Wang, Aizhou
Keywords: Energy Supply; Extended Organ Preservation Time; Lung Transplantation; Mitochondrial Function; Normothermic Ex Vivo Lung Perfusion; Organ Preservation
Expanding our understanding of human cytomegalovirus (HCMV) disease pathogenesis in high-risk lung transplant recipients.
Principal investigators: Ferreira, Victor H
Keywords: Cytokines; Human Cytomegalovirus (Hcmv); Lung Transplantation; Machine Learning; T Cells; Virus-Inclusive Scrna-Seq
MitoRevolution: Mitochondrial Transplantation Transforming Regenerative Medicine - from research to patient care to global impact.
Principal investigators: Andreazza, Ana
Genetic Engineering of Lungs to Create Universal Blood Type Donor Organs
Principal investigators: Cypel, Marcelo; Wang, Aizhou
Keywords: Abo Incompatible Transplant; Crispr; Ex Vivo Lung Perfusion; Genome Editing; Lung Transplantation; Organ Engineering
SAFE LUNG: Short-course Antiviral and Focused Exposure to UV light in LUNG transplantation to prevent transmission of hepatitis B virus from donor organs.
Principal investigators: Ferreira, Victor H; Cypel, Marcelo; Feld, Jordan J; Humar, Atul; Kumar, Deepali
Keywords: Antiviral Treatment; Ex Vivo Organ Perfusion; Hepatitis B Virus; Lung Transplantation
Lung transplant to evaluate advanced novel organ modification therapies using a human decedent model
Principal investigators: Cypel, Marcelo; Gross, Jed A; Humar, Atul
Keywords: Bioethics; Donation; Ex Vivo Lung Perfusion; Human Decedent Model; Lung Transplantation; Organ Modification
Inspiratory Muscle Training in Lung Transplant Candidates and Implications on Early Post-Transplant Outcomes: A Pilot and Feasibility Randomized Clinical Trial
Principal investigators: Rozenberg, Dmitry; Goligher, Ewan C; Reid, Wendy D
Keywords: Diaphragm; Dyspnea; Inspiratory Muscle Training; Lung Transplantation; Post-Operative Outcomes; Respiratory Mechanics
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Thoracic Surgery
- Department of Surgery
- Toronto General Research Institute
- Department of Medicine
- Infectious Diseases
- Critical Care Medicine
- Cell and Systems Biology
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Shaf Keshavjee
Thoracic Surgery
200 shared papers, latest 2026
Mingyao Liu
Department of Surgery
94 shared papers, latest 2026
Kazuhiro Yasufuku
Department of Surgery
63 shared papers, latest 2026
Tereza Martinu
Toronto General Research Institute
35 shared papers, latest 2026
Jonathan Yeung
Department of Surgery
33 shared papers, latest 2026
Lorenzo Del Sorbo
Faculty
25 shared papers, latest 2026
Aizhou Wang
Thoracic Surgery
24 shared papers, latest 2026
Stephen Juvet
Toronto General Research Institute
19 shared papers, latest 2026
Eddy Fan
Department of Medicine
18 shared papers, latest 2023
Thomas Waddell
Thoracic Surgery
13 shared papers, latest 2026
Elliot Wakeam
Department of Surgery
12 shared papers, latest 2026
David Hwang
Cell and Systems Biology
12 shared papers, latest 2025
Atul Humar
Infectious Diseases
11 shared papers, latest 2025
Chung-Wai Chow
Faculty
10 shared papers, latest 2023
Janusz Pawliszyn
Faculty
9 shared papers, latest 2026
Lianne Singer
Physical Therapy
8 shared papers, latest 2025
Deepali Kumar
Infectious Diseases
8 shared papers, latest 2026
Laurent Brochard
Critical Care Medicine
5 shared papers, latest 2025
BO WANG
Faculty
5 shared papers, latest 2026
Andrew Sage
Faculty
4 shared papers, latest 2021
Laveena Munshi
Critical Care Medicine
4 shared papers, latest 2022
Shahid Husain
Department of Medicine
4 shared papers, latest 2022
Andrew Healey
Medicine
4 shared papers, latest 2022
George Tomlinson
Biostatistics Division
3 shared papers, latest 2023
John Granton
Medicine/Respirology
3 shared papers, latest 2023
Wael Hanna
Surgery
3 shared papers, latest 2019
Jim Hu
Faculty
3 shared papers, latest 2024
Jill Rudkowski
Medicine
1 shared papers, latest 2016
Aaron Michael Gazendam
Surgery
1 shared papers, latest 2026
Hong Han
Biochemistry & Biomedical Sciences
1 shared papers, latest 2024
Anhar Alhussaini
Medicine
1 shared papers, latest 2024
Deborah Siegal
Medicine
1 shared papers, latest 2026
Martin Post
Pediatrics and Physiology
1 shared papers, latest 2017
Geoffrey Liu
Epidemiology Division
1 shared papers, latest 2024
David Wishart
Biological Sciences
1 shared papers, latest 2018
Deborah Cook
Medicine
1 shared papers, latest 2016
Jeffrey Medin
Faculty
1 shared papers, latest 2009
Lori West
Pediatrics
1 shared papers, latest 2022
Shaf Keshavjee
Pediatrics
1 shared papers, latest 2018
Monica Parry
Faculty
1 shared papers, latest 2021
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