This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Plasma lipid levels predict chemotherapy response and survival in acute myeloid leukemia.
Blood · 2025
Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.
Cell reports · 2022
Glutamine Metabolism Mediates Sensitivity to Respiratory Complex II Inhibition in Acute Myeloid Leukemia.
Molecular Cancer Research · 2022
Latest funding
- $120,000
Identifying early cancer precursors in individuals at increased risk of developing lymphoma
CIHR · 2025 · Supervisor
- $1,400,000
Canada Research Chair - Tier 1
CIHR · 2023 · Nominated PI
- $956,250
Characterizing the stress granule network as a determinant of leukemic stem cells and novel therapeutic target in acute myeloid leukemia
CIHR · 2022 · Nominated PI
4 publications.
Plasma lipid levels predict chemotherapy response and survival in acute myeloid leukemia.
O'Brien C, Nursimulu N, Tyagi A, Culp-Hill R, Arruda A, Murphy T, Minden MD, Kent A, Stevens B, Pollyea DA, Hope K, Kumar S, Reisz JA, D'Alessandro A, Jones CL
Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.
Devoucoux M, Fort V, Khelifi G, Xu J, Alerasool N, Galloy M, Wong N, Bourriquen G, Fradet-Turcotte A, Taipale M, Hope K, Hussein SMI, Côté J
Glutamine Metabolism Mediates Sensitivity to Respiratory Complex II Inhibition in Acute Myeloid Leukemia.
Roma A, Tcheng M, Ahmed N, Walker S, Jayanth P, Minden MD, Hope K, Nekkar Rao PP, Luc J, Doxey AC
Nuclear localizing sequences promote nuclear translocation and enhance the radiotoxicity of the anti-CD33 monoclonal antibody HuM195 labeled with 111In in human myeloid leukemia cells.
Chen P, Wang J, Hope K, Jin L, Dick J, Cameron R, Brandwein J, Minden M, Reilly RM
Identifying early cancer precursors in individuals at increased risk of developing lymphoma
Principal investigators: Shiba, Yumika
Keywords: Autoimmune Disease; Bioinformatics; Cancer; Early Detection; Genomics; Lupus; Lymphoma; Machine Learning; Transcriptomics
Canada Research Chair - Tier 1
Principal investigators: Hope, Kristin
Keywords: Crc
Characterizing the stress granule network as a determinant of leukemic stem cells and novel therapeutic target in acute myeloid leukemia
Principal investigators: Hope, Kristin
Keywords: Acute Myeloid Leukemia; Leukemic Stem Cells; Pre-Clinical Therapeutic Testing; Proteomics; Stress Granules; Xenotransplantation
Unraveling the role of stress granules for leukemia stem cell maintenance and stress adaptation
Principal investigators: Tajik, Amanda
Keywords: Acute Myeloid Leukemia; Hematopoietic Stem Cells; Leukemia Stem Cells; Stress Granules
Mesenchymal stromal cell dysfunction as a driver of preleukemia
Principal investigators: CHEN, HE TIAN
Keywords: Bone Marrow Microenvironment; Hematopoietic Stem Cells; Pre-Leukemia
Canada Research Chair - Tier 2
Principal investigators: Hope, Kristin
Keywords: C
Development and implementation of computational tools to dissect cancer stem cell circuitry
Principal investigators: Virdee, Suman K
Keywords: Deep Sequencing; Leukaemia; Rna Sequencing; Stem Cell Biology; Translational Bioinformatics
Characterizing the Role of PLAGL2 in the Establishment of Pre-leukemia and Relapse
Principal investigators: Xu, Shu Hua
Keywords: Blood; Chemoresistance; Chemotherapy; Hspc; Leukemia; Plag1; Plagl2; Preleukemia; Stem Cell; Transcriptome
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Medicine
- Medical Biophysics
- Donnelly Centre
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Andrew Doxey
Medicine
1 shared papers, latest 2022
John Dick
Faculty
1 shared papers, latest 2006
Mikko Taipale
Donnelly Centre
1 shared papers, latest 2022
Amélie Fradet-Turcotte
Faculty
1 shared papers, latest 2022
Mark Minden
Medical Biophysics
1 shared papers, latest 2006
Sushant Kumar
Faculty
1 shared papers, latest 2025
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