This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance.
Communications biology · 2023
An improved molecular inversion probe based targeted sequencing approach for low variant allele frequency.
NAR genomics and bioinformatics · 2022
Interacting evolutionary pressures drive mutation dynamics and health outcomes in aging blood.
Nature communications · 2021
Latest funding
- $1,124,550
Using Intravital Imaging to Understand how Acute Myeloid Leukemia Remodels the Bone Marrow Microenvironment In Vivo and how this Impacts Therapeutic Response
CIHR · 2026 · Co-investigator
- $1,591,200
Discovery of sex-dimorphic leukemia-protective programs embedded in human hematopoietic stem cells
CIHR · 2025 · Nominated PI
- $120,000
Population-Scale Hematopoietic Stem Cell Stratification with Progeny-Based Inference
CIHR · 2025 · Supervisor
6 publications.
Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance.
Fan H, Wang F, Zeng A, Murison A, Tomczak K, Hao D, Jelloul FZ, Wang B, Barrodia P, Liang S, Chen K, Wang L, Zhao Z, Rai K, Jain AK, Dick J, Daver N, Futreal A, Abbas HA
An improved molecular inversion probe based targeted sequencing approach for low variant allele frequency.
Biezuner T, Brilon Y, Arye AB, Oron B, Kadam A, Danin A, Furer N, Minden MD, Hwan Kim DD, Shapira S, Arber N, Dick J, Thavendiranathan P, Moskovitz Y, Kaushansky N, Chapal-Ilani N, Shlush LI
Interacting evolutionary pressures drive mutation dynamics and health outcomes in aging blood.
Skead K, Ang Houle A, Abelson S, Agbessi M, Bruat V, Lin B, Soave D, Shlush L, Wright S, Dick J, Morris Q, Awadalla P
Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia.
Cole A, Wang Z, Coyaud E, Voisin V, Gronda M, Jitkova Y, Mattson R, Hurren R, Babovic S, Maclean N, Restall I, Wang X, Jeyaraju DV, Sukhai MA, Prabha S, Bashir S, Ramakrishnan A, Leung E, Qia YH, Zhang N, Combes KR, Ketela T, Lin F, Houry WA, Aman A, Al-Awar R, Zheng W, Wienholds E, Xu CJ, Dick J, Wang JC, Moffat J, Minden MD, Eaves CJ, Bader GD, Hao Z, Kornblau SM, Raught B, Schimmer AD
Messenger RNA Detection in Leukemia Cell lines by Novel Metal-Tagged in situ Hybridization using Inductively Coupled Plasma Mass Spectrometry.
Ornatsky OI, Baranov VI, Bandura DR, Tanner SD, Dick J
Nuclear localizing sequences promote nuclear translocation and enhance the radiotoxicity of the anti-CD33 monoclonal antibody HuM195 labeled with 111In in human myeloid leukemia cells.
Chen P, Wang J, Hope K, Jin L, Dick J, Cameron R, Brandwein J, Minden M, Reilly RM
Using Intravital Imaging to Understand how Acute Myeloid Leukemia Remodels the Bone Marrow Microenvironment In Vivo and how this Impacts Therapeutic Response
Principal investigators: Dacosta, Ralph S
Keywords: Acute Myeloid Leukemia; Bone Marrow; Fluorescence Microscopy; Hypoxia; Immune Cells; Intravital Optical Imaging; Leukemia Treatments; Microvasculature; Transcriptomics; Tumor Microenvironment
Discovery of sex-dimorphic leukemia-protective programs embedded in human hematopoietic stem cells
Principal investigators: Dick, John E; Kaufmann, Kerstin B
Keywords: Acute Myeloid Leukemia Biology,; Early Leukemogenesis; Human Hematopoietic Stem Cells; Human Leukemia Stem Cell Biology; Myeloproliferative Neoplasm Biology; Preleukemia; Sccut&Tag; Sex Dimorphisms; Single Cell Atac/Rna-Sequencing; Target-Seq,
Population-Scale Hematopoietic Stem Cell Stratification with Progeny-Based Inference
Principal investigators: Kang, Ryu Won
Keywords: Blood Malignancies; Gene Expression Programs; Hematopoietic Stem Cells; Precision Medicine; Single Cell Transcriptomics
Discovery of epigenetic determinants regulating stemness to target the eradication of human pre-leukemic and leukemic stem cells
Principal investigators: Dick, John E; Lupien, Mathieu
Keywords: Aml Biology; Crispr-Editing Of Human Hsc; Epigenetics; Human Hematopoietic Stem Cells; Human Leukemia Stem Cells; Non-Coding Regulatory Elements; Pre-Leukemic Human Hsc; Single Cell Atac/Rna-Sequencing; Single Cell Multiomics; Xenografting
Phenotypic and Functional Characterization of Relapse-Fated Cells Present at Diagnosis in AML leading to improved therapeutic targeting and monitoring
Principal investigators: Dick, John E
Keywords: Acute Myeloid Leukemia; Biomarker Development; Early Detection And Monitoring; Leukemic Stem Cells; Pharmacogenomics; Relapse-Origin; Therapeutic Targeting; Xenograft Functional Validation
Investigating the Role of Drug Tolerant Persisters in Driving Colorectal Cancer Metastasis.
Principal investigators: Rehman, Sumaiyah
Keywords: Barcoding; Chemotherapy; Colorectal Cancer; Crispr Screen; Drug Tolerant Persisters; In Vivo; Metastasis; Multiomics; Patient Derived Tumor Models; Relapse
Preparing for the Recovery from the Effects of the PAndemic on cancer control using Real-world Evidence in Canada (PREPARE-Canada)
Principal investigators: Awadalla, Philip; Abelson, Sagi; Alvi, Riaz; Bhatti, Parveen; broet, philippe; Dummer, Trevor J; Kirsh, Victoria; Mclaughlin, John R; Shen-Tu, Grace; Sweeney, Ellen; Turner, Donna C; Urquhart, Robin L
Keywords: Biomarkers; Cancer; Covid-19; Early Detection; Modeling; Screening
Modelling Chr13q Deletion in Human Hematopoietic Stem Cells and its Role in Clonal Hematopoiesis and the Pre-Leukemic State
Principal investigators: Wong, Gordon
Keywords: Age-Related Clonal Hematopoiesis; Crispr-Cas9 Genomic Engineering; Pre-Leukemic Stem Cell; Single-Cell In Vitro Differentiation Assay; Single-Cell Multi-Ome Assay (Atac+Rna-Seq); Xenotransplantation
Evaluating the additional efficacy of metabolic surgery vs optimal medical therapy in type 2 diabetes and cardiovascular disease
Principal investigators: Farkouh, Michael E; Dash, Satya; Poirier, Paul; Woo, Minna N
Keywords: Cardiovascular Disease; Obesity; Type 2 Diabetes
Investigating the therapeutic potential of modulating lysosomal biogenesis in normal and leukemic human hematopoietic stem cells
Principal investigators: Garcia Prat, Laura
Keywords: Autophagy; Chemotherapy Resistance; Hematopoiesis; Hematopoietic Stem Cell Transplant; Hematopoietic Stem Cells; Leukaemia; Leukemia Stem Cells; Lysosomal Biogenesis; Patient-Derived Xenotransplants; Transcription Factor Eb
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Brian Raught and Jason Moffat: 5 shared papers
- Quaid Morris and Philip Awadalla: 2 shared papers
- Brian Raught and Ahmed Aman: 2 shared papers
- Jason Moffat and Ahmed Aman: 2 shared papers
- Quaid Morris and John Dick: 1 shared paper
- Quaid Morris and Jason Moffat: 1 shared paper
- John Dick and Brian Raught: 1 shared paper
- John Dick and Paaladinesh Thavendiranathan: 1 shared paper
- John Dick and Jason Moffat: 1 shared paper
- John Dick and Philip Awadalla: 1 shared paper
- John Dick and Mark Minden: 1 shared paper
- John Dick and Kristin Hope: 1 shared paper
- John Dick and Ahmed Aman: 1 shared paper
- Mark Minden and Kristin Hope: 1 shared paper
- Research Institute
- Genetics and Genome Biology
- Medical Biophysics
- Cardiology
- Occupational and Environmental Health
- Donnelly Centre
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Brian Raught
Research Institute
1 shared papers, latest 2015
Paaladinesh Thavendiranathan
Cardiology
1 shared papers, latest 2022
Jason Moffat
Genetics and Genome Biology
1 shared papers, latest 2015
Philip Awadalla
Occupational and Environmental Health
1 shared papers, latest 2021
Mark Minden
Medical Biophysics
1 shared papers, latest 2006
Kristin Hope
Faculty
1 shared papers, latest 2006
Ahmed Aman
Faculty
1 shared papers, latest 2015
Quaid Morris
Donnelly Centre
1 shared papers, latest 2021
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