Faculty profile

Laurent Briollais

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ProfessorBiostatistics DivisionUniversity of Toronto

Laurent Briollais

Professor

Biostatistics Division

Dalla Lana School of Public Health

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
23 publications in the last five years, latest in 2026.
Senior (last) author on 4 recent papers, a sign of leading a research group.
Principal investigator on 5 research grants (3 NSERC, 2 CIHR), most recently in 2023.
Supervisor on 1 trainee award (1 CIHR), most recently in 2011.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

166

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Brca Gene Breast Cancer Familial Risk Genetic Counselling Mammographic Screening Ovarian Cancer Prophylactic Surgery Risk Prediction

Latest papers

A joint model for a longitudinal outcome and a progressive multistate model under a mixed observation scheme.
Statistical methods in medical research · 2026
Flexible Modeling of Time-Dependent Covariate Effects in Survival Models With Correlated Competing Risks: Application to the Evaluation of Risk-Reducing Salpingo-Oophorectomy in Women With BRCA1 Pathogenic Variants.
Statistics in medicine · 2026
Accommodating the Analysis Model in Multiple Imputation for the Weibull Mixture Cure Model: Performance Under Penalized Likelihood.
Statistics in medicine · 2026

All 67 publications

Latest funding

Therapeutic interventions to prevent colon cancer caused by pks+ E.coli
CIHR · 2025 · Co-investigator
Development of Bayesian Approaches for Next Generation Genetic and Genomic Data
NSERC · 2023 · Principal investigator
$54,000
Biological mechanisms mediating the beneficial effects of immediate mother-infant contact in preterm birth
CIHR · 2021 · Co-investigator
$100,000

All 19 grants and awards

67 publications.

A joint model for a longitudinal outcome and a progressive multistate model under a mixed observation scheme.

Lovblom LE, Briollais L, Perkins BA, Tomlinson G

Statistical methods in medical research2026

DOI: 10.1177/09622802261455480 PMID: 42396836

Flexible Modeling of Time-Dependent Covariate Effects in Survival Models With Correlated Competing Risks: Application to the Evaluation of Risk-Reducing Salpingo-Oophorectomy in Women With BRCA1 Pathogenic Variants.

Lee S, Briollais L, Choi YH, BCFR

Statistics in medicine2026

DOI: 10.1002/sim.70527 PMID: 41944717

Accommodating the Analysis Model in Multiple Imputation for the Weibull Mixture Cure Model: Performance Under Penalized Likelihood.

Xu C, Briollais L, Andrulis IL, Bull SB

Statistics in medicine2026

DOI: 10.1002/sim.70437 PMID: 41840351

Joint Models of Two Longitudinal Biomarkers and Clustered Survival Data for Cluster-Informed Dynamic Prediction With Application to Periodontitis.

Feng SX, Briollais L, Mitani AA

Statistics in medicine2026

DOI: 10.1002/sim.70715 PMID: 42706960

Characterizing the SARS-CoV-2 antibody response and associations with patient factors: Serological profiling of participants enrolled in the GENCOV study

Morgan G, Fung CYJ, Gingras A-C, Colwill K, Briollais L, Frangione E, Wolday D, Qi F, Pasculescu A, Delgado-Brand M

Clinical Biochemistry20253 citations

DOI: 10.1016/j.clinbiochem.2024.110859

COVID-19 vaccine reactogenicity among participants enrolled in the GENCOV study

Morgan G, Casalino S, Chowdhary S, Frangione E, Fung CYJ, Lapadula E, Arnoldo S, Bearss E, Binnie A, Borgundvaag B

Vaccine20242 citations

DOI: 10.1016/j.vaccine.2024.03.030

Modeling multiple correlated end-organ disease trajectories: A tutorial for multistate and joint models with applications in diabetes complications.

Lovblom LE, Briollais L, Perkins BA, Tomlinson G

Statistics in medicine2024

DOI: 10.1002/sim.9984 PMID: 38118464

A marginalized two-part joint model for a longitudinal biomarker and a terminal event with application to advanced head and neck cancers.

Rustand D, Briollais L, Rondeau V

Pharmaceutical statistics2024

DOI: 10.1002/pst.2338 PMID: 37717945

Trivariate Joint Modeling for Family Data with Longitudinal Counts, Recurrent Events and a Terminal Event with Application to Lynch Syndrome.

Lu J, Yi GY, Rustand D, Parfrey P, Briollais L, Choi YH

Statistics in medicine2024

DOI: 10.1002/sim.10210 PMID: 39278641

Characterizing Risk Factors for Hospitalization and Clinical Characteristics in a Cohort of COVID-19 Patients Enrolled in the GENCOV Study

Morgan G, Casalino S, Chowdhary S, Frangione E, Fung CYJ, Haller S, Lapadula E, Scott M, Wolday D, Young J

Viruses20236 citations

DOI: 10.3390/v15081764

Therapeutic interventions to prevent colon cancer caused by pks+ E.coli

Co-investigatorCIHR2025Team Grant: Bringing Biology to Cancer Prevention - General Pool

Principal investigators: Martin, Alberto; Armstrong, Heather; Croitoru, Kenneth

Keywords: Carbohydrate; Colon Cancer; Diet; Fibre; Gut Microbes; Inflammatory Bowel Disease; Lynch Syndrome; Mismatch Repair; Pks+E.Coli

Development of Bayesian Approaches for Next Generation Genetic and Genomic Data

Principal investigatorNSERC2023Discovery Grants Program - Individual

Principal investigators: Briollais, Laurent

Keywords: Bayesian statistics; Cancer genetics; Graphical models; High-dimensional data; High throughput data; MCMC algorithms; Multi-omic data; Personalized medicine; Predictive modeling; Statistical genetics

$54,000

Biological mechanisms mediating the beneficial effects of immediate mother-infant contact in preterm birth

Co-investigatorCIHR2021Project Grant - PA: Mental Health and Resilience In The Early Years

Principal investigators: McGowan, Patrick O

Keywords: Biomarkers; Breastfeeding; Dna Methylation Modifications; Endocrinology; Neurodevelopment; Parental Care; Preterm Birth; Stress Response

$100,000

Healthy Life Trajectories Initiative (HeLTI) - South Africa - Bukhali

Co-investigatorCIHR2021Team Grant: Healthy Life Trajectories Initiative (HeLTI) - South Africa

Principal investigators: Lye, Stephen J; Clinton, Jean M; Lule, Elizabeth L; Connor, Kristin L; Draper, Catherine E; Hung, Rayjean; Norris, Shane A

Keywords: Child Health And Development Outcomes; Childhood Adiposity; Clinical Trial; Developmental Origins Of Health And Disease; Maternal-Child Health; Non-Communicable Disease; Preconception, Pregnancy And Infancy Intervention

$2,500,000

Placental contributions to maternal and fetal health outcomes: Lipid signatures in diabetes mellitus in pregnancy

Co-investigatorCIHR2020Project Grant

Principal investigators: Caniggia, Isabella

Keywords: Diabetes; Endothelial Cells; Endothelial Dysfunction; Fetal Growth; Lipids; Mass Spectrometry; Metformin; Mitochondrial Dynamics; Placenta; Preeclampsia

$997,180

Using MRI imaging to develop a personalized risk-based breast cancer screening strategy

Co-investigatorCIHR2019Project Grant

Principal investigators: Martel, Anne L; Brooks, Jennifer D

Keywords: Breast Screening; Chemoprevention; High Risk Screening Population; Machine Learning; Magnetic Resonance Imaging; Mammography; Medical Image Analysis; Radiomics; Risk Assessment

$925,650

Extending risk prediction models for hereditary breast ovarian cancer (HBOC)

Nominated PICIHR2019Project Grant

Principal investigators: Briollais, Laurent

Keywords: Brca Gene; Breast Cancer; Familial Risk; Genetic Counselling; Mammographic Screening; Ovarian Cancer; Prophylactic Surgery; Risk Prediction; Statistical Modelling; Survival Analysis

$630,667

Programming the gut microbiome for child growth and development: a multi-national intervention study.

Co-investigatorCIHR2018Team Grant: Canadian Microbiome Initiative 2: Research Teams - LOI

Principal investigators: Comelli, Elena M; Connor, Kristin L

Keywords: Child Growth And Development; Cohort Studies; Developmental Origins Of Health And Disease; Intervention; Microbiome; Nutrition; Obesity; Pregnancy

$25,000

Understanding early life origins of sex difference in insulin sensitivity

Co-investigatorCIHR2017Catalyst Grant: Sex as a Variable in Biomedical Research

Principal investigators: Luo, Zhong-Cheng

Keywords: Developmental Origins Of Health And Disease; Insulin Resistance; Pregnancy; Sex Difference

$150,000

BUilding Knowledge and a foundation for HeALthy lIfe trajectories: BUKHALI Trial.

Co-investigatorCIHR2017Team Grant: Healthy Life Trajectories Initiative (HeLTI) - South-Africa

Principal investigators: Lye, Stephen J; Matthews, Stephen G; Norris, Shane A; Richter, Linda

Keywords: Child Cognitive Development; Child Development; Cohort Studies; Developmental Origins Of Health And Disease; Nutrition; Obesity; Pregnancy

$2,478,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on July 30, 2025 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Laurent Briollais

Research

Latest papers

Latest funding

A joint model for a longitudinal outcome and a progressive multistate model under a mixed observation scheme.

Flexible Modeling of Time-Dependent Covariate Effects in Survival Models With Correlated Competing Risks: Application to the Evaluation of Risk-Reducing Salpingo-Oophorectomy in Women With BRCA1 Pathogenic Variants.

Accommodating the Analysis Model in Multiple Imputation for the Weibull Mixture Cure Model: Performance Under Penalized Likelihood.

Joint Models of Two Longitudinal Biomarkers and Clustered Survival Data for Cluster-Informed Dynamic Prediction With Application to Periodontitis.

Characterizing the SARS-CoV-2 antibody response and associations with patient factors: Serological profiling of participants enrolled in the GENCOV study

COVID-19 vaccine reactogenicity among participants enrolled in the GENCOV study

Modeling multiple correlated end-organ disease trajectories: A tutorial for multistate and joint models with applications in diabetes complications.

A marginalized two-part joint model for a longitudinal biomarker and a terminal event with application to advanced head and neck cancers.

Trivariate Joint Modeling for Family Data with Longitudinal Counts, Recurrent Events and a Terminal Event with Application to Lynch Syndrome.

Characterizing Risk Factors for Hospitalization and Clinical Characteristics in a Cohort of COVID-19 Patients Enrolled in the GENCOV Study

Development of Bayesian Approaches for Next Generation Genetic and Genomic Data

Frequent collaborators

Yun-Hee Choi

Bharati Bapat

Stephen Lye

Jennifer Taher

Jordan Lerner-Ellis

Neil Fleshner

Zhong-Cheng Luo

Dawit Wolday

Vasundara Venkateswaran

Yun-Hee Choi

Tony Mazzulli

Wei Xu

Cindy-Lee Dennis

Patrick Parfrey

Yvonne Bombard

George Tomlinson

Anne-Claude Gingras

Kellie Murphy

Pablo Nepomnaschy

Maryam Faiz

Nika Shakiba

Steven Gallinger

Jehonathan Pinthus

Geoffrey Liu

John Kingdom

Zdenka Pausova

Stephen Scherer

Laura Anderson

Jennifer Jenkins

Deborah Sloboda