Faculty profile

Anne-Claude Gingras

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ProfessorDepartment of Molecular GeneticsUniversity of Toronto

Anne-Claude Gingras

Professor

Department of Molecular Genetics

Temerty Faculty of Medicine

University of Toronto

Toronto, Ontario, Canada

Canada Research Chair in Functional Proteomics

Scholar ORCID

Supervision signals

Professors usually supervise graduate students in their department's programs.
147 publications in the last five years, latest in 2026.
Senior (last) author on 9 recent papers, a sign of leading a research group.
Principal investigator on 22 research grants (19 CIHR, 3 NSERC), most recently in 2025.
Supervised 7 trainees who won CIHR awards, most recently in 2020.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

331

Publications

282

Citations

h-index

194

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Education

Profiles and links

University Profile Personal Website Google Scholar iDORCID

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Signals and details

Research

Read how they describe their research on their University of Toronto profile.

Mass Spectrometry Proteomics Protein-Protein Interactions Copy Number Alterations In Vivo Crispr Screening Kras Laser Capture Microdissection Lung Cancer

Latest papers

Mitotic single-stranded DNA suppression by DDIAS.
Molecular cell · 2026
Proteomic investigation of signaling dynamics: from static maps to network rewiring.
Bioscience reports · 2026 · senior author
Serological Benefit of SARS-CoV-2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia.
Pediatric blood & cancer · 2026

All 331 publications

Latest funding

Advancing lung cancer biology through integrated spatial proteomics and in vivo CRISPR screening
CIHR · 2025 · Nominated PI
$1,415,252
Advancing lung cancer biology through integrated spatial proteomics and in vivo CRISPR screening
CIHR · 2025 · Nominated PI
$100,000
In-depth characterization of signal rewiring by kinase truncations in cancers
CIHR · 2024 · Nominated PI
$65,000

All 60 grants and awards

From the 150 most recent of 331 publications.

Mitotic single-stranded DNA suppression by DDIAS.

Xue Y, Rashed FB, Mao DYL, Abe KT, Lin ZY, Krastev DB, Setiaputra D, Hoeg L, Bonnet C, Kumar A, Mavousian A, Maan A, Harvey-Jones E, Pettitt SJ, Tutt ANJ, Lord CJ, Sicheri F, Gingras AC, Durocher D

Molecular cell2026

DOI: 10.1016/j.molcel.2026.07.034 PMID: 42636809

Proteomic investigation of signaling dynamics: from static maps to network rewiring.

Dionne U, Vafaee K, Hesketh GG, Gingras AC

Bioscience reports2026Senior author

DOI: 10.1042/bsr20250116 PMID: 42460659

Serological Benefit of SARS-CoV-2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia.

Shapiro JR, Qi F, Colwill K, Dorogy AD, Liu Y, Science M, Gingras AC, Rini JM, Gupta S, Alexander S, Bolotin S, Watts TH

Pediatric blood & cancer2026

DOI: 10.1002/1545-5017.70395 PMID: 42135995

The spectrum of copy number variation in the Pan-Canadian HostSeq databank.

Aujla N, Thiruvahindrapuram B, Casalino S, Frangione E, Mahajan R, Di Iorio D, Fung CYJ, Jayachandran L, MacDonald G, Morgan G, Wolday D, Young J, Arshad M, Clausen M, Arnoldo S, Binnie A, Borgundvaag B, Chowdhary S, Dagher M, Devine L, Friedman SM, Gingras AC, Goneau LW, Khan Z, Lapadula E, Mazzulli T, McGeer A, McLeod S, Mighton C, Pugh TJ, Richardson D, Simpson J, Stern S, Taher A, Strug L, Bombard Y, Faghfoury H, Greenfeld E, CGEn HostSeq Initiative, Scherer SW, Taher J, Noor A, Lerner-Ellis J

PloS one2026

DOI: 10.1371/journal.pone.0359210 PMID: 42789588

Preserved SARS-CoV-2 T-cell responses despite impaired humoral immunity in children with profound B-cell lymphopenia.

Nantel S, Sassine S, Bourdin B, Barbosa Da Torre M, Sutton G, Rabezanahary H, Qi F, Ward LA, Delgado-Brand M, Adams K, Sheikh-Mohamed S, Wang L, Nicholson S, Laghdir Z, Colwill K, Chao G, Seifried L, Liu Y, Rini JM, Gommerman J, Gingras AC, Baz M, Zinzser K, Quach C, Decaluwe H

NPJ vaccines2026

DOI: 10.1038/s41541-026-01525-6 PMID: 42477358

Early COVID-19 and Severity of Subsequent Omicron Infection in Ontario Canada.

Kassee C, Shigayeva A, Kandel C, Farooqi L, Zhong Z, Gingras AC, Coleman BL, Gilbert L, Gold WL, Major M, Mazzulli T, Mubareka S, Valluri SR, Martin C, Kyaw MH, McLaughlin JM, McGeer A

Influenza and other respiratory viruses2026

DOI: 10.1111/irv.70197 PMID: 41527184

The molecular glue CLEO4-88 inhibits the ACAA1 thiolase by induced binding to GID4.

Chana CK, Ben Makhlouf I, Kim J, Yu AJY, Moatti N, Orlicky S, Wong CJ, Baronijan L, Tang X, Mao D, Larsen B, McGary L, Seale B, Mader P, Ceccarelli DF, Barbulescu P, Martin A, Durocher D, Pelletier L, Gingras AC, Sicheri F

Nature chemical biology2026

DOI: 10.1038/s41589-026-02183-4 PMID: 41957281

SARS-CoV-2 infection in female sex workers from Nairobi, Kenya early in the COVID-19 pandemic: Seroincidence and behavioural associations.

Yang SD, Qi F, Colwill K, Gingras AC, Beattie TS, Kimani J, Kaul R

PloS one2026

DOI: 10.1371/journal.pone.0327692 PMID: 42296081

Immunogenicity of COVID-19 booster vaccines in children receiving immunosuppressive medications.

Shapiro JR, Choi F, Xu A, Duong TT, Gingras AC, Colwill K, Bernatsky S, Benseler SM, Yeung RS, SUCCEED KIDS Team

Pediatric research2026

DOI: 10.1038/s41390-025-04174-y PMID: 40691289

Assessing SARS-CoV-2 immune markers in vaccinated asymptomatic adults after household exposure in Canada (AB-PROTECT): a prospective cohort study

Kandel C, Breznik JA, Taylor M, Colwill K, Hu Q, Llanes A, Crowl G, Elliott HD, Shi G, Li XA

The Lancet Microbe2026

DOI: 10.1016/j.lanmic.2026.101500

Advancing lung cancer biology through integrated spatial proteomics and in vivo CRISPR screening

Nominated PICIHR2025Project Grant

Principal investigators: Gingras, Anne-Claude; Schramek, Daniel

Keywords: Copy Number Alterations; In Vivo Crispr Screening; Kras; Laser Capture Microdissection; Lung Cancer; Mass Spectrometry; Multi-Omics; Oncogenes; Spatial Proteomics; Tumor Microenvironment

$1,415,252

Advancing lung cancer biology through integrated spatial proteomics and in vivo CRISPR screening

Nominated PICIHR2025Project Grant - Priority Announcement: Early Detection/Cancer Prevention

Principal investigators: Gingras, Anne-Claude; Schramek, Daniel

Keywords: Copy Number Alterations; In Vivo Crispr Screening; Kras; Laser Capture Microdissection; Lung Cancer; Mass Spectrometry; Multi-Omics; Oncogenes; Spatial Proteomics; Tumor Microenvironment

$100,000

In-depth characterization of signal rewiring by kinase truncations in cancers

Nominated PICIHR2024CIHR - ICR / Cancer Research Society Partnership - Res. Grants - Breast Cancer

Principal investigators: Gingras, Anne-Claude

Keywords: Breast Cancer

$65,000

Avian influenza suRveillance in Companion animal and Human healthcare settings [ARCH]

Co-investigatorCIHR2024Catalyst Grant: Avian Influenza OneHealth Research

Principal investigators: Fralick, Michael P; Hug, Laura A; Kassen, Rees; MacFadden, Derek R; Nott, Caroline; Wong, Alex

Keywords: Animal Shelters; Avian Influenza A; Environmental Surface Surveillance; H5n1; Hospitals; One Health; Pandemic Surveillance; Veterinary Clinics; Whole Genome Sequencing; Wildlife Rehabilitation

$150,000

Deciphering Long Covid - Investigating Immune Dysfunction and Novel Pathways

Co-investigatorCIHR2024Project Grant - PA: Pandemic Preparedness and Health Emergencies Research

Principal investigators: Ostrowski, Mario A

Keywords: B Cell; Covid-19; Cytokine; Ebv; Immunity; Long Covid; Sars-Cov-2; T Cell

$100,000

Prepare, REact, Collect, Innovate, Share and Engage (PRECISE) Diagnostic Platform

Co-investigatorSSHRC2023Canada Biomedical Research Fund and Biosciences Research Infrastructure Fund

Principal investigators: Di Paolo, Caitlin

Keywords: pandemic; emerging infectious disease; diagnostics; biomanufacturing; cohort study; public health; emergency preparedness; biomanufacturing talent development; community engagement; novel assays; biomarkers; molecular diagnostics; serology; point-of-care diagnostics; pathogen characterization

$9,296,000

Kinase translocations in cancer: commonalities and differences in mechanisms of action

Nominated PICIHR2022Project Grant

Principal investigators: Gingras, Anne-Claude

Keywords: Bioid; Biomolecular Condensates; Cancer; Interaction Proteomics; Kinase; Microscopy; Proteomics; Proximity-Dependent Biotinylation; Signal Transduction; Translocations

$1,113,075

Host cell reorganization by SARS-CoV-2

Co-investigatorCIHR2022Project Grant

Principal investigators: Raught, Brian

Keywords: Cellular Organization; Mass Spectrometry; Proteomics; Proximity-Dependent Biotinylation (Bioid); Viral Replication Organelle

$100,000

COVID-19 in working age Canadian adults: Long-term follow up of infections and immune responses

Co-investigatorCIHR2022Operating Grant: COVID-19 - Project Grant

Principal investigators: Coleman, Brenda L

Keywords: Adult; Cohort; Correlates Of Protection; Covid-19; Education; Epidemiology; Health Care

$867,001

Dynamic proximity maps of human cells

Nominated PICIHR2022Project Grant

Principal investigators: Gingras, Anne-Claude

Keywords: Bioid; Cell Biology; Cell Cycle; Cellular Organization; Data Analysis; Data Visualization; Mass Spectrometry; Organelles; Proteomics; Proximity-Dependent Biotinylation

$1,403,775

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Anne-Claude Gingras

Research

Latest papers

Latest funding

Mitotic single-stranded DNA suppression by DDIAS.

Proteomic investigation of signaling dynamics: from static maps to network rewiring.

Serological Benefit of SARS-CoV-2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia.

The spectrum of copy number variation in the Pan-Canadian HostSeq databank.

Preserved SARS-CoV-2 T-cell responses despite impaired humoral immunity in children with profound B-cell lymphopenia.

Early COVID-19 and Severity of Subsequent Omicron Infection in Ontario Canada.

The molecular glue CLEO4-88 inhibits the ACAA1 thiolase by induced binding to GID4.

SARS-CoV-2 infection in female sex workers from Nairobi, Kenya early in the COVID-19 pandemic: Seroincidence and behavioural associations.

Immunogenicity of COVID-19 booster vaccines in children receiving immunosuppressive medications.

Assessing SARS-CoV-2 immune markers in vaccinated asymptomatic adults after household exposure in Canada (AB-PROTECT): a prospective cohort study

Prepare, REact, Collect, Innovate, Share and Engage (PRECISE) Diagnostic Platform

Frequent collaborators

Brian Raught

Frank Sicheri

Allison McGeer

Laurence Pelletier

Daniel Durocher

Samira Mubareka

Jason Moffat

Mikko Taipale

Ji-Young Youn

Charles Boone

Mario Ostrowski

Tony Mazzulli

Atul Humar

Kevin Yau

Deepali Kumar

Vinod Chandran

Jean-Philippe Lambert

Jordan Lerner-Ellis

Jennifer Taher

Nahum Sonenberg

Dawn Bowdish

Rupert Kaul

Ahmed Aman

Margaret Larche

Dawit Wolday

Jennifer Gommerman

Chris Verschoor

Jessica Breznik

Karen Mossman

Jack Greenblatt

Jonathan Bramson

Stéphane Richard

Jun Liu

Stephane Angers

Hong Han

Jean-Simon Diallo

Matthew S Miller

William Sheffield

Andrew Costa

Mathieu Laplante