Michal Opas, University of Toronto

Research

Ca Binding Proteins Development Es Cells Heart Development

Latest papers

Osteogenic Differentiation from Mouse Embryonic Stem Cells.
Methods in molecular biology (Clifton, N.J.) · 2022 · senior author
c-Src kinase inhibits osteogenic differentiation via enhancing STAT1 stability.
PloS one · 2020 · senior author
Calreticulin regulates Src kinase in osteogenic differentiation from embryonic stem cells.
Stem cell research · 2020 · senior author

All 26 publications

Latest funding

Cadherin switch: its regulation and downstream effects on cardiomyogenesis in mouse embryonic stem cells
CIHR · 2013 · Nominated PI
$740,665
A calreticulin-cytomechanical switch in osteoblast-adipocyte fate choice in an ES cell model
CIHR · 2010 · Nominated PI
$569,575
Cardiac Calreticulin: Cell & Developmental Biology
CIHR · 2009 · Nominated PI
$706,375

All 4 grants and awards

26 publications.

01

Osteogenic Differentiation from Mouse Embryonic Stem Cells.

Alvandi Z, Opas M

Methods in molecular biology (Clifton, N.J.)2022Senior author

DOI: 10.1007/7651_2021_436 PMID: 34611818

02

c-Src kinase inhibits osteogenic differentiation via enhancing STAT1 stability.

Alvandi Z, Opas M

PloS one2020Senior author

DOI: 10.1371/journal.pone.0241646 PMID: 33180789

03

Calreticulin regulates Src kinase in osteogenic differentiation from embryonic stem cells.

Alvandi Z, Al-Mansoori LJR, Opas M

Stem cell research2020Senior author

DOI: 10.1016/j.scr.2020.101972 PMID: 32916637

04

Calreticulin regulates a switch between osteoblast and chondrocyte lineages derived from murine embryonic stem cells.

Pilquil C, Alvandi Z, Opas M

The Journal of biological chemistry2020Senior author

DOI: 10.1074/jbc.ra119.011029 PMID: 32220932

05

Calreticulin Is Required for TGF-β-Induced Epithelial-to-Mesenchymal Transition during Cardiogenesis in Mouse Embryonic Stem Cells.

Karimzadeh F, Opas M

Stem cell reports2017Senior author

DOI: 10.1016/j.stemcr.2017.03.018 PMID: 28434939

06

Osteogenic Differentiation from Embryonic Stem Cells.

Yu Y, Pilquil C, Opas M

Methods in molecular biology (Clifton, N.J.)2016Senior author

DOI: 10.1007/7651_2014_126 PMID: 25417061

07

Optimized osteogenic differentiation protocol from R1 mouse embryonic stem cells in vitro.

Yu Y, Al-Mansoori L, Opas M

Differentiation; research in biological diversity2015Senior author

DOI: 10.1016/j.diff.2014.12.003 PMID: 25613029

08

Calreticulin affects cell adhesiveness through differential phosphorylation of insulin receptor substrate-1.

Czarnowski A, Papp S, Szaraz P, Opas M

Cellular & molecular biology letters2014Senior author

DOI: 10.2478/s11658-014-0181-9 PMID: 24470116

09

Both chondroinduction and proliferation account for growth of cartilage nodules in mouse limb bud cultures.

Malko AV, Villagomez M, Aubin JE, Opas M

Stem cell reviews and reports2013Senior author

DOI: 10.1007/s12015-013-9434-7 PMID: 23447083

10

Expression of survivin in human oocytes and preimplantation embryos.

Balakier H, Xiao R, Zhao J, Zaver S, Dziak E, Szczepanska K, Opas M, Yie S, Librach C

Fertility and sterility2013

DOI: 10.1016/j.fertnstert.2012.09.020 PMID: 23084269

Cadherin switch: its regulation and downstream effects on cardiomyogenesis in mouse embryonic stem cells

Nominated PICIHR2013Operating Grant

Principal investigators: Opas, Michal J

Keywords: Ca Binding Proteins; Development; Es Cells; Heart Development

$740,665

A calreticulin-cytomechanical switch in osteoblast-adipocyte fate choice in an ES cell model

Nominated PICIHR2010Operating Grant

Principal investigators: Opas, Michal J

Keywords: Ca Binding Proteins; Chondro/Osteogenesis; Development; Es Cells

$569,575

Cardiac Calreticulin: Cell & Developmental Biology

Nominated PICIHR2009Operating Grant

Principal investigators: Opas, Michal J

Keywords: Adhesion & Cytoskeleton; Calcium Binding Proteins; Cardiomyocyte; Cardiomyogenesis; Es Cells; Heart

$706,375

A calreticulin-cytomechanical switch in osteoblast-adipocyte fate choice in an ES cell model

Nominated PICIHR2008Operating Grant: Fall 2008 Priority Announcement (IMHA)

Principal investigators: Opas, Michal J

Keywords: Ca Binding Proteins; Chondro/Osteogenesis; Development

$91,870

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Laboratory Medicine & Pathobiology
Biology
Department of Physiology

Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Peter Backx

Department of Physiology

1 shared papers, latest 2010

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Subject: Prospective PhD student: Ca Binding Proteins Dear Professor Opas, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Osteogenic Differentiation from Mouse Embryonic Stem Cells." (2022), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Michal Opas

Research

Latest papers

Latest funding

Osteogenic Differentiation from Mouse Embryonic Stem Cells.

c-Src kinase inhibits osteogenic differentiation via enhancing STAT1 stability.

Calreticulin regulates Src kinase in osteogenic differentiation from embryonic stem cells.

Calreticulin regulates a switch between osteoblast and chondrocyte lineages derived from murine embryonic stem cells.

Calreticulin Is Required for TGF-&#x3b2;-Induced Epithelial-to-Mesenchymal Transition during Cardiogenesis in Mouse Embryonic Stem Cells.

Osteogenic Differentiation from Embryonic Stem Cells.

Optimized osteogenic differentiation protocol from R1 mouse embryonic stem cells in vitro.

Calreticulin affects cell adhesiveness through differential phosphorylation of insulin receptor substrate-1.

Both chondroinduction and proliferation account for growth of cartilage nodules in mouse limb bud cultures.

Expression of survivin in human oocytes and preimplantation embryos.

Cadherin switch: its regulation and downstream effects on cardiomyogenesis in mouse embryonic stem cells

A calreticulin-cytomechanical switch in osteoblast-adipocyte fate choice in an ES cell model

Cardiac Calreticulin: Cell & Developmental Biology

A calreticulin-cytomechanical switch in osteoblast-adipocyte fate choice in an ES cell model

Frequent collaborators

Peter Backx

Peter Backx

Calreticulin Is Required for TGF-β-Induced Epithelial-to-Mesenchymal Transition during Cardiogenesis in Mouse Embryonic Stem Cells.