Faculty profile

Myuri Ruthirakuhan

ResearcherNeurologyUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.

Myuri Ruthirakuhan

Researcher

Neurology

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
17 publications in the last five years, latest in 2026.
Principal investigator on 1 research grant (1 CIHR), most recently in 2023.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Publications

Citations

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Aging Cardiovascular Risk Factors Coronary Artery Disease Diabetes Physical Activity

Latest papers

Targeting Brain Cholesterol Homeostasis in Alzheimer's Disease: Mechanisms and Therapeutic Perspectives.
Journal of neurochemistry · 2026 · first author
Apoptosis protein markers in comorbid type 2 diabetes mellitus and depression; relationships with cognitive performance, incident dementia, and white matter hyperintensities.
Journal of affective disorders · 2026
Uncovering lipid biomarkers linked to methylphenidate efficacy in treating apathy in Alzheimer's disease: insights from the ADMET 2 trial.
Alzheimer's research & therapy · 2026 · first author

All 30 publications

Latest funding

Dementia risk mitigation in individuals with cardiovascular disease
CIHR · 2023 · Nominated PI
$135,000
Pro-Resolving Inflammatory Mediators in Neurovascular Gains in Aerobic Training; a phase 2, double-blind, randomized placebo-controlled trial (PRIMiNG-AT2)
CIHR · 2023 · Co-investigator
$20,000

All 2 grants and awards

30 publications.

Targeting Brain Cholesterol Homeostasis in Alzheimer's Disease: Mechanisms and Therapeutic Perspectives.

Ruthirakuhan M, Taha AY, Swardfager W

Journal of neurochemistry2026First author

DOI: 10.1111/jnc.70492 PMID: 42283223

Apoptosis protein markers in comorbid type 2 diabetes mellitus and depression; relationships with cognitive performance, incident dementia, and white matter hyperintensities.

Perfetto SE, Ruthirakuhan M, Wong YY, Ryoo SW, Huang CHL, Fan F, Chenoweth MJ, Nestor SM, Andreazza AC, Goubran M, Rabin JS, Jiang G, Black SE, Cogo-Moreira H, MacIntosh BJ, Swardfager W

Journal of affective disorders2026

DOI: 10.1016/j.jad.2026.122353 PMID: 42556583

Uncovering lipid biomarkers linked to methylphenidate efficacy in treating apathy in Alzheimer's disease: insights from the ADMET 2 trial.

Ruthirakuhan M, Mills M, Rosenberg P, Haughey N, Mintzer J, Brawman-Mintzer O, Craft S, Herrmann N, Lerner AJ, Levey AI, Padala PR, Porsteinsson A, van Dyck CH, Shade D, Lanctôt KL

Alzheimer's research & therapy2026First author

DOI: 10.1186/s13195-026-02055-y PMID: 42178577

Efficacy and Safety of Cannabinoids for Neuropsychiatric Symptoms of Dementia: A Systematic Review with Meta-analysis.

Pan TJ, Wang HJ, Siddiqui A, Kurumala D, Ruthirakuhan M, Swardfager W, Marotta G, Lanctôt KL

CNS drugs2026

DOI: 10.1007/s40263-026-01277-w PMID: 41748849

Identifying a combination of biomarkers to predict treatment response to nabilone for agitation in Alzheimer's disease - an exploratory post hoc analysis.

Wang HJ, Ruthirakuhan M, Andreazza AC, Beroncal EL, Black SE, Gallagher D, Herrmann N, Kiss A, Verhoeff NPLG, Lanctôt KL

Neurodegenerative disease management2026

DOI: 10.1080/17582024.2025.2587549 PMID: 41220257

Cardiovascular risk factors and vascular neuropathological findings in primary age-related tauopathy versus Alzheimer's disease.

Xiong LY, Ruthirakuhan M, Ryoo SW, Wu CY, Edwards JD, Rabin JS, Tartaglia MC, Black SE, Keith J, Swardfager W

GeroScience2026

DOI: 10.1007/s11357-026-02164-4 PMID: 41741895

Assessment of clinical factors that predict response to nabilone for agitation in Alzheimer's disease: A post hoc analysis of a randomized placebo-controlled trial.

Feldman OJ, Herrmann N, Ruthirakuhan M, Gallagher D, L G Verhoeff NP, Kiss A, Black SE, Lanctôt KL

International psychogeriatrics2026

DOI: 10.1016/j.inpsyc.2026.100183 PMID: 41530008

Peripheral biomarkers associated with apathy and predicting response to methylphenidate: Secondary analysis of the Apathy in Dementia Methylphenidate Trial 2 (ADMET2) study.

Sankhe K, Ruthirakuhan M, Andreazza AC, Brawman-Mintzer O, Craft S, Herrmann N, Ismail Z, Lerner AJ, Levey AI, Mintzer J, Padala PR, Perin J, Porsteinsson AP, Rosenberg PB, Shade D, Tumati S, van Dyck CH, Lanctôt KL

International psychogeriatrics2026

DOI: 10.1016/j.inpsyc.2025.100181 PMID: 41521126

Type 2 Diabetes Mellitus, Cognitive Performance, and Incident Dementia; Identifying Mediating Pathways and Biomarkers From the Plasma Proteome.

Perfetto SE, Ruthirakuhan M, Ryoo SW, Wong YY, Xiong LY, Anita NZ, Caveney NA, Edgar LJ, Newman JW, Cogo-Moreira H, Swardfager W

Journal of neurochemistry2025

DOI: 10.1111/jnc.70306 PMID: 41342355

Metabolic and vascular contributions to dementia: Soluble epoxide hydrolase-derived linoleic acid oxylipins and glycemic status are related to cerebral small vessel disease markers, atrophy, and cognitive performance.

Ryoo SW, Lin WZ, Magliocco A, Ruthirakuhan M, Wong YY, Perfetto SE, Huang C, Anita NZ, Arnott SR, Lang AE, Symons S, Hegele RA, Goubran M, Ramirez J, Ottoy J, Rabin JS, MacIntosh BJ, Lanctôt KL, Liang N, Cogo-Moreira H, Taha AY, Swardfager W, ONDRI Investigators

Alzheimer's & dementia : the journal of the Alzheimer's Association2025

DOI: 10.1002/alz.70718 PMID: 41059602

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Myuri Ruthirakuhan

Research

Latest papers

Latest funding

Targeting Brain Cholesterol Homeostasis in Alzheimer's Disease: Mechanisms and Therapeutic Perspectives.

Apoptosis protein markers in comorbid type 2 diabetes mellitus and depression; relationships with cognitive performance, incident dementia, and white matter hyperintensities.

Uncovering lipid biomarkers linked to methylphenidate efficacy in treating apathy in Alzheimer's disease: insights from the ADMET 2 trial.

Efficacy and Safety of Cannabinoids for Neuropsychiatric Symptoms of Dementia: A Systematic Review with Meta-analysis.

Identifying a combination of biomarkers to predict treatment response to nabilone for agitation in Alzheimer's disease - an exploratory post hoc analysis.

Cardiovascular risk factors and vascular neuropathological findings in primary age-related tauopathy versus Alzheimer's disease.

Assessment of clinical factors that predict response to nabilone for agitation in Alzheimer's disease: A post hoc analysis of a randomized placebo-controlled trial.

Peripheral biomarkers associated with apathy and predicting response to methylphenidate: Secondary analysis of the Apathy in Dementia Methylphenidate Trial 2 (ADMET2) study.

Type 2 Diabetes Mellitus, Cognitive Performance, and Incident Dementia; Identifying Mediating Pathways and Biomarkers From the Plasma Proteome.

Metabolic and vascular contributions to dementia: Soluble epoxide hydrolase-derived linoleic acid oxylipins and glycemic status are related to cerebral small vessel disease markers, atrophy, and cognitive performance.

Dementia risk mitigation in individuals with cardiovascular disease

Pro-Resolving Inflammatory Mediators in Neurovascular Gains in Aerobic Training; a phase 2, double-blind, randomized placebo-controlled trial (PRIMiNG-AT2)

Frequent collaborators

Nathan Herrmann

Walter Swardfager

Damien Gallagher

Julie Ottoy

Zahinoor Ismail

Maged Goubran

Howard Chertkow

Andrew Frank

Dar Dowlatshahi

Sanjeev Kumar

Gustavo Saposnik

Neil Rector

Margaret Richter

Robert Bartha

Michael Borrie

Mario Masellis

Demetrios Sahlas

Pedro Rosa-Neto

Michael Borrie

Howard Chertkow

Jennifer Mandzia

Amy Cheung

Robert Bartha

Ekaterina Rogaeva

Elizabeth Finger

Matteo DiScipio