Faculty profile

Rajiv Gandhi

ResearcherOrthopedicsUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.

Rajiv Gandhi

Researcher

Orthopedics

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
21 publications in the last five years, latest in 2026.
Principal investigator on 1 research grant (1 CIHR), most recently in 2026.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

129

Publications

1,208

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

Search on Google Scholar

Find them onX · LinkedIn · Bluesky · YouTube

Signals and details

Research

Artificial Intelligence Deep Learning Endotypes Genomics Knee Osteoarthritis Machine Learning Methylomics Multi-Omics Integration

Latest papers

Suggestive Association Between Tryptophan-indole Metabolic Pathway and Total Joint Arthroplasty Early Revision for Heterogeneous Failure Modes in Patients With Primary Osteoarthritis: A Meta-analysis of Metabolomics.
Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
Responders vs. non-responders to mesenchymal stromal cells in knee osteoarthritis: Mechanistic correlates of donor cell and patient features.
Stem cell reports · 2026
Identification of Ephrin type-B receptor 4 as a critical mediator of tissue fibrosis.
JCI insight · 2025

All 129 publications

Latest funding

Application of Multi-Omics and Deep Learning for Endotyping and Theratyping in Osteoarthritis
CIHR · 2026 · Principal investigator
$726,752
Nanobiomaterial for synergetic reduction of friction and inflammation in osteoarthritis
SSHRC · 2023 · Co-investigator
$250,000
Contribution of synovial fibroblast cell subsets to the pathogenesis of knee osteoarthritis
CIHR · 2023 · Co-investigator
$531,675

All 11 grants and awards

129 publications.

Suggestive Association Between Tryptophan-indole Metabolic Pathway and Total Joint Arthroplasty Early Revision for Heterogeneous Failure Modes in Patients With Primary Osteoarthritis: A Meta-analysis of Metabolomics.

Liu M, Gill R, Gandhi R, Huang J, Furey A, Perruccio A, Rampersaud R, Mahomed NN, Rahman P, Kapoor M, Zhai G

Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews2026

DOI: 10.5435/jaaosglobal-d-25-00285 PMID: 41802117

Responders vs. non-responders to mesenchymal stromal cells in knee osteoarthritis: Mechanistic correlates of donor cell and patient features.

Robb KP, Rabani R, Vohra S, Singh S, Chahal J, Audet J, Perruccio AV, Naraghi A, Gandhi R, Espin-Garcia O, Viswanathan S

Stem cell reports2026

DOI: 10.1016/j.stemcr.2026.103024 PMID: 42561945

Identification of Ephrin type-B receptor 4 as a critical mediator of tissue fibrosis.

Wu B, Lively SS, Vohra S, Fine N, Pastrello C, Maglaviceanu A, Espin-Garcia O, Pollock-Tahiri E, Nakamura S, Kaur P, Delos Santos K, Rockel JS, Potla P, Gupta H, Datta P, Tang L, Kwon J, Nakamura A, Buechler MB, Gandhi R, Wu J, Hinz B, Jurisica I, Kapoor M

JCI insight2025

DOI: 10.1172/jci.insight.189156 PMID: 41424388

Sex Matters: Investigating the Influence of Presurgery Factors on Pain and Physical Function following Total Joint Arthroplasty for Osteoarthritis.

Perruccio AV, Power JD, Sundararajan K, Canizares M, Davey JR, Gandhi R, Syed K, Veillette C, Kapoor M, Mahomed NN, Rampersaud YR

JB & JS open access2025

DOI: 10.2106/jbjs.oa.25.00232 PMID: 41185850

Total Hip Arthroplasty versus Education and Exercise: A Secondary Analysis of Propensity Matched Data Comparing Outcomes Across Hip Osteoarthritis Symptom Severity.

Young JJ, Zywiel MG, Skou ST, Chandran V, Davey JR, Gandhi R, Mahomed NN, Syed K, Veillette CJH, Rampersaud YR, Perruccio AV

The Journal of arthroplasty2025

DOI: 10.1016/j.arth.2025.04.032 PMID: 40841100

Deep learning-based clustering for endotyping and post-arthroplasty response classification using knee osteoarthritis multiomic data.

Rockel JS, Sharma D, Espin-Garcia O, Hueniken K, Sandhu A, Pastrello C, Sundararajan K, Potla P, Fine N, Lively SS, Perry K, Mahomed NN, Syed K, Jurisica I, Perruccio AV, Rampersaud YR, Gandhi R, Kapoor M

Annals of the rheumatic diseases2025

DOI: 10.1016/j.ard.2025.01.012 PMID: 39948003

Cell and transcriptomic diversity of infrapatellar fat pad during knee osteoarthritis.

Peters H, Potla P, Rockel JS, Tockovska T, Pastrello C, Jurisica I, Delos Santos K, Vohra S, Fine N, Lively S, Perry K, Looby N, Li SH, Chandran V, Hueniken K, Kaur P, Perruccio AV, Mahomed NN, Rampersaud R, Syed K, Gracey E, Krawetz R, Buechler MB, Gandhi R, Kapoor M

Annals of the rheumatic diseases2025

DOI: 10.1136/ard-2024-225928 PMID: 39919907

Total Knee Arthroplasty Versus Education and Exercise for Knee Osteoarthritis: A Propensity-Matched Analysis.

Young JJ, Zywiel MG, Skou ST, Chandran V, Davey JR, Gandhi R, Mahomed NN, Syed K, Veillette CJH, Rampersaud YR, Perruccio AV

Arthritis care & research2024

DOI: 10.1002/acr.25293 PMID: 38191793

Total Hip Arthroplasty Versus Education and Exercise: A Propensity-Matched Analysis of 266 Patients Who Have Hip Osteoarthritis.

Young JJ, Zywiel MG, Skou ST, Chandran V, Davey JR, Gandhi R, Mahomed NN, Syed K, Veillette CJH, Rampersaud YR, Perruccio AV

The Journal of arthroplasty2024

DOI: 10.1016/j.arth.2024.04.072 PMID: 38697319

Understanding the epidemiology and perceived efficacy of cannabis use in patients with chronic musculoskeletal pain.

Leroux T, Ajrawat P, Sundararajan K, Maldonado-Rodriguez N, Ravi B, Gandhi R, Rampersaud R, Veillette C, Mahomed N, Clarke H

Journal of cannabis research2024

DOI: 10.1186/s42238-024-00231-1 PMID: 38961506

Application of Multi-Omics and Deep Learning for Endotyping and Theratyping in Osteoarthritis

Principal investigatorCIHR2026Project Grant

Principal investigators: Sharma, Divya; Gandhi, Rajiv; Kapoor, Mohit; Perruccio, Anthony; Rampersaud, Y. Raja; Rice, Sarah J

Keywords: Artificial Intelligence; Deep Learning; Endotypes; Genomics; Knee Osteoarthritis; Machine Learning; Methylomics; Multi-Omics Integration; Proteomics; Theratypes

$726,752

Nanobiomaterial for synergetic reduction of friction and inflammation in osteoarthritis

Co-investigatorSSHRC2023New Frontiers in Research Fund - Exploration

Principal investigators: Viswanathan, Sowmya

Keywords: Osteoarthritis; Synovial inflammation; Reactive oxygen species; Cartilage; Biomaterials; Nanoparticles; Lubricants; Friction coefficient; Drug deliver

$250,000

Contribution of synovial fibroblast cell subsets to the pathogenesis of knee osteoarthritis

Co-investigatorCIHR2023Project Grant

Principal investigators: Kapoor, Mohit

Keywords: Fibrosis; Inflammation; Osteoarthritis; Sequencing; Synovium; Transcriptomics

$531,675

Contribution of synovial cell subsets to the pathogenesis of knee osteoarthritis

Co-investigatorCIHR2022Project Grant - PA: Epigenetics/epigenomics in human health or disease

Principal investigators: Kapoor, Mohit

Keywords: Animal Models; Fibrosis; Inflammation; Osteoarthritis; Sequencing; Synovium; Transcriptomics

$100,000

Refining the molecular endotypes for precision medicine of osteoarthritis

Co-investigatorCIHR2020Project Grant

Principal investigators: Zhai, Guangju

Keywords: Endotypes; Genomics; Metabolomics; Osteoarthritis

$971,550

Role and therapeutic potential of MicroRNA-34a-5p in knee osteoarthritis

Co-investigatorCIHR2020Project Grant

Principal investigators: Kapoor, Mohit

Keywords: Antisense Oligonucleotide; Biomarkers; Cartilage; Knee; Microrna; Osteoarthritis; Synovium

$409,275

Role and therapeutic potential of MicroRNA-34a-5p in knee osteoarthritis

Co-investigatorCIHR2019Project Grant - PA: Epigenetics/epigenomics in human health or disease

Principal investigators: Kapoor, Mohit

Keywords: Antisense Oligonucleotide; Biomarkers; Cartilage; Knee; Microrna; Osteoarthritis; Synovium

$100,000

Workshop on Early Knee Osteoarthritis: Novel biomarkers, Diagnostics, Therapeutics and Clinical Cohorts for Early Detection and Intervention

Co-investigatorCIHR2016Planning and Dissemination Grant - Institute Community Support

Principal investigators: Kapoor, Mohit

Keywords: Biomarkers; Computational Biology; Drug Discovery; Epidemiology; Knee; Oa Clinical Cohort; Oa Diagnostics; Oa Therapeutic Targets; Osteoarthritis

$9,916

ULK1 (most upstream autophagy inducer) as a potential therapeutic target in Osteoarthritis

Co-investigatorCIHR2016Project Grant

Principal investigators: Kapoor, Mohit

Keywords: Animal Models; Apoptosis; Autophagy; Chondrocytes; Chondroprotection; Knee Joint; Osteoarthritis; Unc Like Kinase-1 (Ulk1)

$393,976

Sex Differences in the Association Between Inflammatory Biomarkers and Knee OA Pain

Co-investigatorCIHR2015Operating Grant - PA: IMHA - New Invest.- Musculoskeletal Health Bridge Funding

Principal investigators: Perruccio, Anthony

Keywords: Inflammation; Osteoarthritis; Pain; Sex

$100,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2026

Subject: Prospective PhD student: Artificial Intelligence Dear Professor Gandhi, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Suggestive Association Between Tryptophan-indole Metabolic Pathway and Total Joint Arthroplasty Early Revision for Heterogeneous Failure Modes in Patients With Primary Osteoarthritis: A Meta-analysis of Metabolomics." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Application of Multi-Omics and Deep Learning for Endotyping and Theratyping in Osteoarthritis" (2026), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Something wrong or missing on this profile? Suggest a correction

Rajiv Gandhi

Research

Latest papers

Latest funding

Suggestive Association Between Tryptophan-indole Metabolic Pathway and Total Joint Arthroplasty Early Revision for Heterogeneous Failure Modes in Patients With Primary Osteoarthritis: A Meta-analysis of Metabolomics.

Responders vs. non-responders to mesenchymal stromal cells in knee osteoarthritis: Mechanistic correlates of donor cell and patient features.

Identification of Ephrin type-B receptor 4 as a critical mediator of tissue fibrosis.

Sex Matters: Investigating the Influence of Presurgery Factors on Pain and Physical Function following Total Joint Arthroplasty for Osteoarthritis.

Total Hip Arthroplasty versus Education and Exercise: A Secondary Analysis of Propensity Matched Data Comparing Outcomes Across Hip Osteoarthritis Symptom Severity.

Deep learning-based clustering for endotyping and post-arthroplasty response classification using knee osteoarthritis multiomic data.

Cell and transcriptomic diversity of infrapatellar fat pad during knee osteoarthritis.

Total Knee Arthroplasty Versus Education and Exercise for Knee Osteoarthritis: A Propensity-Matched Analysis.

Total Hip Arthroplasty Versus Education and Exercise: A Propensity-Matched Analysis of 266 Patients Who Have Hip Osteoarthritis.

Understanding the epidemiology and perceived efficacy of cannabis use in patients with chronic musculoskeletal pain.

Nanobiomaterial for synergetic reduction of friction and inflammation in osteoarthritis

Frequent collaborators

Mohit Kapoor

Vinod Chandran

Fahad Razak

Fahad Razak

David Wasserstein

Bheeshma Ravi

Igor Jurisica

Sowmya Viswanathan

Osvaldo Espin Garcia

Timothy Leroux

Mohit Bhandari

Anuj Bhatia

Konstantin Shestopaloff

Osvaldo Espin Garcia

Roman Krawetz

Holly Smith

Guangju Zhai

Moin Khan

Mohit Kapoor

Boris Hinz

Johanne Martel-Pelletier

Anthony Perruccio

Rick Lau

Hassan Fahmi

Frances Chung

Anahi Perlas