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Konstantin Shestopaloff

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Adjunct LecturerBiostatistics DivisionUniversity of Toronto

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Latest papers

DCMD: Distance-based classification using mixture distributions on microbiome data.
PLoS computational biology · 2021 · first author
Investigating Molecular Signatures Underlying Trapeziometacarpal Osteoarthritis Through the Evaluation of Systemic Cytokine Expression.
Frontiers in immunology · 2021
MicroRNA-34a-5p Promotes Joint Destruction During Osteoarthritis.
Arthritis & rheumatology (Hoboken, N.J.) · 2021

All 15 publications

15 publications.

DCMD: Distance-based classification using mixture distributions on microbiome data.

Shestopaloff K, Dong M, Gao F, Xu W

PLoS computational biology2021First author

DOI: 10.1371/journal.pcbi.1008799 PMID: 33711013

Investigating Molecular Signatures Underlying Trapeziometacarpal Osteoarthritis Through the Evaluation of Systemic Cytokine Expression.

Ratneswaran A, Rockel JS, Antflek D, Matelski JJ, Shestopaloff K, Kapoor M, Baltzer H

Frontiers in immunology2021

DOI: 10.3389/fimmu.2021.794792 PMID: 35126358

MicroRNA-34a-5p Promotes Joint Destruction During Osteoarthritis.

Endisha H, Datta P, Sharma A, Nakamura S, Rossomacha E, Younan C, Ali SA, Tavallaee G, Lively S, Potla P, Shestopaloff K, Rockel JS, Krawetz R, Mahomed NN, Jurisica I, Gandhi R, Kapoor M

Arthritis & rheumatology (Hoboken, N.J.)2021

DOI: 10.1002/art.41552 PMID: 33034147

Effect of autotaxin inhibition in a surgically-induced mouse model of osteoarthritis.

Datta P, Gandhi R, Nakamura S, Lively S, Rossomacha E, Potla P, Shestopaloff K, Endisha H, Pastrello C, Jurisica I, Rockel JS, Kapoor M

Osteoarthritis and cartilage open2020

DOI: 10.1016/j.ocarto.2020.100080 PMID: 36474685

Bone Marrow Mesenchymal Stromal Cell Treatment in Patients with Osteoarthritis Results in Overall Improvement in Pain and Symptoms and Reduces Synovial Inflammation.

Chahal J, Gómez-Aristizábal A, Shestopaloff K, Bhatt S, Chaboureau A, Fazio A, Chisholm J, Weston A, Chiovitti J, Keating A, Kapoor M, Ogilvie-Harris DJ, Syed KA, Gandhi R, Mahomed NN, Marshall KW, Sussman MS, Naraghi AM, Viswanathan S

Stem cells translational medicine2019

DOI: 10.1002/sctm.18-0183 PMID: 30964245

A classification modeling approach for determining metabolite signatures in osteoarthritis.

Rockel JS, Zhang W, Shestopaloff K, Likhodii S, Sun G, Furey A, Randell E, Sundararajan K, Gandhi R, Zhai G, Kapoor M

PloS one2018

DOI: 10.1371/journal.pone.0199618 PMID: 29958292

Analyzing differences between microbiome communities using mixture distributions.

Shestopaloff K, Escobar MD, Xu W

Statistics in medicine2018First author

DOI: 10.1002/sim.7896 PMID: 30039541

FUT2 genotype and secretory status are not associated with fecal microbial composition and inferred function in healthy subjects

Turpin W, Bedrani L, Espin-Garcia O, Xu W, Silverberg MS, Smith MI, Guttman DS, Griffiths A, Moayyedi P, Panaccione R

Gut Microbes201848 citations

DOI: 10.1080/19490976.2018.1445956

Germline INDELs and CNVs in a cohort of colorectal cancer patients: their characteristics, associations with relapse-free survival time, and potential time-varying effects on the risk of relapse.

Werdyani S, Yu Y, Skardasi G, Xu J, Shestopaloff K, Xu W, Dicks E, Green J, Parfrey P, Yilmaz YE, Savas S

Cancer medicine2017

DOI: 10.1002/cam4.1074 PMID: 28544645

Association of host genome with intestinal microbial composition in a large healthy cohort.

Turpin W, Espin-Garcia O, Xu W, Silverberg MS, Kevans D, Smith MI, Guttman DS, Griffiths A, Panaccione R, Otley A, Xu L, Shestopaloff K, Moreno-Hagelsieb G, GEM Project Research Consortium, Paterson AD, Croitoru K

Nature genetics2016

DOI: 10.1038/ng.3693 PMID: 27694960

Profile data last refreshed on July 30, 2025 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Konstantin Shestopaloff

Latest papers

DCMD: Distance-based classification using mixture distributions on microbiome data.

Investigating Molecular Signatures Underlying Trapeziometacarpal Osteoarthritis Through the Evaluation of Systemic Cytokine Expression.

MicroRNA-34a-5p Promotes Joint Destruction During Osteoarthritis.

Effect of autotaxin inhibition in a surgically-induced mouse model of osteoarthritis.

Bone Marrow Mesenchymal Stromal Cell Treatment in Patients with Osteoarthritis Results in Overall Improvement in Pain and Symptoms and Reduces Synovial Inflammation.

A classification modeling approach for determining metabolite signatures in osteoarthritis.

Analyzing differences between microbiome communities using mixture distributions.

FUT2 genotype and secretory status are not associated with fecal microbial composition and inferred function in healthy subjects

Germline INDELs and CNVs in a cohort of colorectal cancer patients: their characteristics, associations with relapse-free survival time, and potential time-varying effects on the risk of relapse.

Association of host genome with intestinal microbial composition in a large healthy cohort.

Frequent collaborators

Wei Xu

Mohit Kapoor

Rajiv Gandhi

Patrick Parfrey

Sevtap Savas

Anne Griffiths

Kenneth Croitoru

Igor Jurisica

Remo Panaccione

Osvaldo Espin Garcia

Sowmya Viswanathan

Paul Moayyedi

Vasily Giannakeas

Roman Krawetz

Guangju Zhai

Barry Rosen

Karen Madsen

Anthony Otley

Edward Randell

Guang Sun