Faculty profile

Jiangping Wu

ResearcherMedicineUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.

Jiangping Wu

Researcher

Medicine

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
3 publications in the last five years, latest in 2025.
Senior (last) author on 1 recent paper, a sign of leading a research group.
Principal investigator on 6 research grants (3 NSERC, 3 CIHR), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Adrenal Gland Hyperplasia Armc5 Neural Tube Defects Pol Ii Pool Size Polr2a (Rpb1)Protein Degradation Rna Polymerase Ii (Pol Ii)Ubiquitin Ligase

Latest papers

Identification of Ephrin type-B receptor 4 as a critical mediator of tissue fibrosis.
JCI insight · 2025
ARMC5 controls the degradation of most Pol II subunits, and ARMC5 mutation increases neural tube defect risks in mice and humans.
Genome biology · 2024 · senior author
Cooccurring Type 1 Diabetes Mellitus and Autoimmune Thyroiditis in a Girl with Craniofrontonasal Syndrome: Are EFNB1 Variants Associated with Autoimmunity?
Pharmaceuticals (Basel, Switzerland) · 2022

All 40 publications

Latest funding

The role and mechanisms of EPHB4 in controlling heart rhythm
NSERC · 2024 · Principal investigator
$47,000
To study the pathogenesis and its underlying mechanisms of an abnormally large Pol II pool size caused by a defective novel ARMC5-containing POLR2A-specific ubiquitin ligase
CIHR · 2021 · Nominated PI
$780,300
To roles of EPH kinases in regulating catecholamine secretion in chromaffin cells
NSERC · 2017 · Principal investigator
$168,000

All 6 grants and awards

40 publications.

Identification of Ephrin type-B receptor 4 as a critical mediator of tissue fibrosis.

Wu B, Lively SS, Vohra S, Fine N, Pastrello C, Maglaviceanu A, Espin-Garcia O, Pollock-Tahiri E, Nakamura S, Kaur P, Delos Santos K, Rockel JS, Potla P, Gupta H, Datta P, Tang L, Kwon J, Nakamura A, Buechler MB, Gandhi R, Wu J, Hinz B, Jurisica I, Kapoor M

JCI insight2025

DOI: 10.1172/jci.insight.189156 PMID: 41424388

ARMC5 controls the degradation of most Pol II subunits, and ARMC5 mutation increases neural tube defect risks in mice and humans.

Luo H, Lao L, Au KS, Northrup H, He X, Forget D, Gauthier MS, Coulombe B, Bourdeau I, Shi W, Gagliardi L, Fragoso MCBV, Peng J, Wu J

Genome biology2024Senior author

DOI: 10.1186/s13059-023-03147-w PMID: 38225631

Cooccurring Type 1 Diabetes Mellitus and Autoimmune Thyroiditis in a Girl with Craniofrontonasal Syndrome: Are EFNB1 Variants Associated with Autoimmunity?

Güneş S, Wu J, Özyılmaz B, Deveci Sevim R, Ünüvar T, Anık A

Pharmaceuticals (Basel, Switzerland)2022

DOI: 10.3390/ph15121535 PMID: 36558986

A Variant in the Nicotinic Acetylcholine Receptor Alpha 3 Subunit Gene Is Associated With Hypertension Risks in Hypogonadic Patients.

Wu T, Wang Y, Shi W, Zhang BQ, Raelson J, Yao YM, Wu HD, Xu ZX, Marois-Blanchet FC, Ledoux J, Blunck R, Sheng JZ, Hu SJ, Luo H, Wu J

Frontiers in genetics2020Senior author

DOI: 10.3389/fgene.2020.539862 PMID: 33329690

The receptor tyrosine kinase EPHB6 regulates catecholamine exocytosis in adrenal gland chromaffin cells.

Shi W, Ye B, Rame M, Wang Y, Cioca D, Reibel S, Peng J, Qi S, Vitale N, Luo H, Wu J

The Journal of biological chemistry2020Senior author

DOI: 10.1074/jbc.ra120.013251 PMID: 32321761

EPHB6 controls catecholamine biosynthesis by up-regulating tyrosine hydroxylase transcription in adrenal gland chromaffin cells.

Shi W, Wang Y, Peng J, Qi S, Vitale N, Kaneda N, Murata T, Luo H, Wu J

The Journal of biological chemistry2019Senior author

DOI: 10.1074/jbc.ra118.005767 PMID: 30824540

Analysis of the association of EPHB6, EFNB1 and EFNB3 variants with hypertension risks in males with hypogonadism.

Wu T, Zhang BQ, Raelson J, Yao YM, Wu HD, Xu ZX, Marois-Blanchet FC, Tahir MR, Wang Y, Bradley WE, Luo H, Wu J, Sheng JZ, Hu SJ

Scientific reports2018

DOI: 10.1038/s41598-018-32836-x PMID: 30262919

EPHB6 and testosterone in concert regulate epinephrine release by adrenal gland chromaffin cells.

Wang Y, Shi W, Blanchette A, Peng J, Qi S, Luo H, Ledoux J, Wu J

Scientific reports2018Senior author

DOI: 10.1038/s41598-018-19215-2 PMID: 29339804

ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis.

Lagares D, Ghassemi-Kakroodi P, Tremblay C, Santos A, Probst CK, Franklin A, Santos DM, Grasberger P, Ahluwalia N, Montesi SB, Shea BS, Black KE, Knipe R, Blati M, Baron M, Wu B, Fahmi H, Gandhi R, Pardo A, Selman M, Wu J, Pelletier JP, Martel-Pelletier J, Tager AM, Kapoor M

Nature medicine2017

DOI: 10.1038/nm.4419 PMID: 29058717

Discovery of benzofuran-3(2H)-one derivatives as novel DRAK2 inhibitors that protect islet β-cells from apoptosis.

Wang S, Xu L, Lu YT, Liu YF, Han B, Liu T, Tang J, Li J, Wu J, Li JY, Yu LF, Yang F

European journal of medicinal chemistry2017

DOI: 10.1016/j.ejmech.2017.02.048 PMID: 28249207

The role and mechanisms of EPHB4 in controlling heart rhythm

Principal investigatorNSERC2024Discovery Grants Program - Individual

Principal investigators: Wu, Jiangping

Keywords: ephb4 kinase; hcn4; kinase substrate profiling; cell signaling; gene knockout mice; embryonic stem cells; transcription factors

$47,000

To study the pathogenesis and its underlying mechanisms of an abnormally large Pol II pool size caused by a defective novel ARMC5-containing POLR2A-specific ubiquitin ligase

Nominated PICIHR2021Project Grant

Principal investigators: Wu, Jiangping

Keywords: Adrenal Gland Hyperplasia; Armc5; Neural Tube Defects; Pol Ii Pool Size; Polr2a (Rpb1); Protein Degradation; Rna Polymerase Ii (Pol Ii); Ubiquitin Ligase

$780,300

To roles of EPH kinases in regulating catecholamine secretion in chromaffin cells

Principal investigatorNSERC2017Discovery Grants Program - Individual

Principal investigators: Wu, Jiangping

$168,000

Roles of Eph receptor tyrosine kinases and their ligands ephrins in pathogenesis and prognosis of chronic inflammatory diseases

Nominated PICIHR2012Team Grant: Health Challenges in Chronic Inflammation Initiative (LOI)

Principal investigators: Wu, Jiangping; Kapoor, Mohit; Martel-Pelletier, Johanne; Prat, Alexandre

Keywords: Chronic Inflammation; Eph Kinases; Ephrins; Gene Knock Our Mice; Multiple Sclerosis; Osteoarthritis; Prognosis; Rheumatoid Arthritis; Therapeutic Targets

$20,000

The role of ephrinB1 and ephrinB2 in controling gamma-delta T cell development

Principal investigatorNSERC2012Discovery Grants Program - Individual

Principal investigators: Wu, Jiangping

$170,000

Use of TGFbi to improve the efficacy of islet transplantation and promote islet regeneration

Nominated PICIHR2012Operating Grant

Principal investigators: Wu, Jiangping

Keywords: Gene Knockout Mice; Islet Survival; Islet Transplantation; Tgfbi; Transgenic Mice; Type I Diabetes

$600,626

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Jiangping Wu

Research

Latest papers

Latest funding

Identification of Ephrin type-B receptor 4 as a critical mediator of tissue fibrosis.

ARMC5 controls the degradation of most Pol II subunits, and ARMC5 mutation increases neural tube defect risks in mice and humans.

Cooccurring Type 1 Diabetes Mellitus and Autoimmune Thyroiditis in a Girl with Craniofrontonasal Syndrome: Are EFNB1 Variants Associated with Autoimmunity?

A Variant in the Nicotinic Acetylcholine Receptor Alpha 3 Subunit Gene Is Associated With Hypertension Risks in Hypogonadic Patients.

The receptor tyrosine kinase EPHB6 regulates catecholamine exocytosis in adrenal gland chromaffin cells.

EPHB6 controls catecholamine biosynthesis by up-regulating tyrosine hydroxylase transcription in adrenal gland chromaffin cells.

Analysis of the association of EPHB6, EFNB1 and EFNB3 variants with hypertension risks in males with hypogonadism.

EPHB6 and testosterone in concert regulate epinephrine release by adrenal gland chromaffin cells.

ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis.

Discovery of benzofuran-3(2H)-one derivatives as novel DRAK2 inhibitors that protect islet &#x3b2;-cells from apoptosis.

The role and mechanisms of EPHB4 in controlling heart rhythm

To study the pathogenesis and its underlying mechanisms of an abnormally large Pol II pool size caused by a defective novel ARMC5-containing POLR2A-specific ubiquitin ligase

To roles of EPH kinases in regulating catecholamine secretion in chromaffin cells

Roles of Eph receptor tyrosine kinases and their ligands ephrins in pathogenesis and prognosis of chronic inflammatory diseases

The role of ephrinB1 and ephrinB2 in controling gamma-delta T cell development

Use of TGFbi to improve the efficacy of islet transplantation and promote islet regeneration

Frequent collaborators

Johanne Tremblay

Eric Thorin

Eric Thorin

Mohit Kapoor

Mohit Kapoor

Hassan Fahmi

Johanne Martel-Pelletier

Mohit Kapoor

Guy Cloutier

Jonathan Ledoux

Pavel Hamet

Rajiv Gandhi

Murray Baron

Alexandre Prat

Osvaldo Espin Garcia

Igor Jurisica

Alain Lamarre

Rikard Blunck

Michel Tremblay

Boris Hinz

Discovery of benzofuran-3(2H)-one derivatives as novel DRAK2 inhibitors that protect islet β-cells from apoptosis.