Faculty profile
Ulrich Tepass
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses may be missing. Find their university profile.
Research
Latest papers
The α-Catenin mechanosensing M region is required for cell adhesion during tissue morphogenesis.
The Journal of cell biology · 2023 · senior author
Crumbs complex-directed apical membrane dynamics in epithelial cell ingression.
The Journal of cell biology · 2022 · senior author
Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain.
eLife · 2020
Latest funding
- $960,076
Dynamic molecular and cellular mechanisms driving epithelial cell ingression
CIHR · 2023 · Nominated PI
- $250,000
Epithelial Polarity and Development
NSERC · 2022 · Principal investigator
- $914,175
Adherens junction dynamics and function in epithelial tissue morphogenesis
CIHR · 2022 · Nominated PI
28 publications.
The α-Catenin mechanosensing M region is required for cell adhesion during tissue morphogenesis.
Sheppard L, Green DG, Lerchbaumer G, Rothenberg KE, Fernandez-Gonzalez R, Tepass U
Crumbs complex-directed apical membrane dynamics in epithelial cell ingression.
Simões S, Lerchbaumer G, Pellikka M, Giannatou P, Lam T, Kim D, Yu J, Ter Stal D, Al Kakouni K, Fernandez-Gonzalez R, Tepass U
Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain.
Ye H, Ojelade SA, Li-Kroeger D, Zuo Z, Wang L, Li Y, Gu JY, Tepass U, Rodal AA, Bellen HJ, Shulman JM
Identification of Genes Required for Apical Protein Trafficking in Drosophila Photoreceptor Cells.
Laffafian A, Tepass U
Role of α-Catenin and its mechanosensing properties in regulating Hippo/YAP-dependent tissue growth.
Sarpal R, Yan V, Kazakova L, Sheppard L, Yu JC, Fernandez-Gonzalez R, Tepass U
Apical polarity proteins recruit the RhoGEF Cysts to promote junctional myosin assembly.
Silver JT, Wirtz-Peitz F, Simões S, Pellikka M, Yan D, Binari R, Nishimura T, Li Y, Harris TJC, Perrimon N, Tepass U
Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions.
Ishiyama N, Sarpal R, Wood MN, Barrick SK, Nishikawa T, Hayashi H, Kobb AB, Flozak AS, Yemelyanov A, Fernandez-Gonzalez R, Yonemura S, Leckband DE, Gottardi CJ, Tepass U, Ikura M
Unique cell biological profiles of retinal disease-causing missense mutations in the polarity protein Crumbs.
Pellikka M, Tepass U
Myosin II promotes the anisotropic loss of the apical domain during Drosophila neuroblast ingression.
Simões S, Oh Y, Wang MFZ, Fernandez-Gonzalez R, Tepass U
Muscle versus Snail: Muscle wins.
Simoes S, Tepass U
Dynamic molecular and cellular mechanisms driving epithelial cell ingression
Principal investigators: Tepass, Ulrich
Keywords: Cancer; Cell Adhesion; Cell Ingression; Cell Polarity; Computer Modeling; Drosophila; Epithelial-Mesenchymal Transition; Genetic Analysis; Image Analysis
Epithelial Polarity and Development
Principal investigators: Tepass, Ulrich
Keywords: Cell Polarity; Cell Adhesion; Genetic Model System; Tissue Morphogenesis; Drosophila; Cell Ingression; Epithelial-mesenchymal transition; Stem Cells; Cancer; Blindness
Adherens junction dynamics and function in epithelial tissue morphogenesis
Principal investigators: Tepass, Ulrich
Keywords: Adherens Junction; Cadherin; Cancer; Catenin; Cell Adhesion; Cell Polarity; Cell Shape; Cytoskeleton; Epithelia; Morphogenesis
Mechanisms regulating epithelial stem cell behaviour
Principal investigators: Tepass, Ulrich
Keywords: epithelia; stem cells; proliferation; cell competition; cell adhesion; hippo pathway; cadherin; catenin; ferm domain; drosophila
Upgrades for essential imaging platforms at a multi-user microscope facility
Principal investigators: Tepass, Ulrich
Dynamic molecular and cellular mechanisms driving epithelial cell ingression
Principal investigators: Tepass, Ulrich
Keywords: Cancer; Cell Adhesion; Cell Extrusion; Cell Ingression; Cell Polarity; Development; Embryo; Epithelial-Mesenchymal Transition; Genetic Model System; Neural Stem Cells
Epithelial Polarity and Development
Principal investigators: Tepass, Ulrich
Organization and function of the interface between cadherin and the cytoskeleton
Principal investigators: Tepass, Ulrich
a-catenin and its binding partners in adherens junction assembly and function
Principal investigators: Tepass, Ulrich
Keywords: Cadherin; Catenin; Cell Adhesion; In Vivo Analysis; Transgenesis
Epithelial Polarity and Development
Principal investigators: Tepass, Ulrich
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Ulrich Tepass and Rodrigo Fernandez-Gonzalez: 5 shared papers
- Ulrich Tepass and Dorothea Godt: 3 shared papers
- Ulrich Tepass and Mitsuhiko Ikura: 2 shared papers
- Derek van der Kooy and Ulrich Tepass: 1 shared paper
- Derek van der Kooy and Dorothea Godt: 1 shared paper
- Ulrich Tepass and Patrick Laprise: 1 shared paper
- Ulrich Tepass and Maurice Ringuette: 1 shared paper
- Ulrich Tepass and Belinda Chang: 1 shared paper
- Mitsuhiko Ikura and Rodrigo Fernandez-Gonzalez: 1 shared paper
- Patrick Laprise and Rodrigo Fernandez-Gonzalez: 1 shared paper
- Maurice Ringuette and Belinda Chang: 1 shared paper
- Department of Cell & Systems Biology
- Institute of Biomedical Engineering
- PM Research
- Ecology and Evolutionary Biology (St. George Campus)
- Department of Molecular Genetics
- Cell and Systems Biology (St. George Campus)
- Biologie moléculaire, biochimie médicale et pathologie
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Rodrigo Fernandez-Gonzalez
Institute of Biomedical Engineering
5 shared papers, latest 2023
Dorothea Godt
Department of Cell & Systems Biology
3 shared papers, latest 2012
Mitsuhiko Ikura
PM Research
2 shared papers, latest 2018
Patrick Laprise
Biologie moléculaire, biochimie médicale et pathologie
1 shared papers, latest 2015
Maurice Ringuette
Cell and Systems Biology (St. George Campus)
1 shared papers, latest 2009
Belinda Chang
Ecology and Evolutionary Biology (St. George Campus)
1 shared papers, latest 2009
Derek van der Kooy
Department of Molecular Genetics
1 shared papers, latest 2009
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