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Research
Latest papers
Primary mismatch repair deficient glioma, IDH-wildtype and H3-wildtype: A giant cell tumor with potential for long-term survival occurring at all ages.
Neuro-oncology · 2026
Reirradiation for Patients With Recurrent Ependymoma Across the Age Spectrum.
Advances in radiation oncology · 2026
The impact of international care networks on the clinical management of constitutional mismatch repair deficiency (CMMRD): a review of recent developments.
Familial cancer · 2026
Latest funding
- $1,275,640
Towards immune based combinations for the treatment of IDH1 mutant replication repair deficient gliomas
CIHR · 2026 · Nominated PI
- $1,342,576
Next generation precision oncology for pediatric-type AYA gliomas
CIHR · 2022 · Co-investigator
- $235,500
Imaging-based classification and treatment response prediction of pediatric low-grade gliomas for precision child health
CIHR · 2022 · Co-investigator
From the 150 most recent of 278 publications.
Primary mismatch repair deficient glioma, IDH-wildtype and H3-wildtype: A giant cell tumor with potential for long-term survival occurring at all ages.
Suwala AK, Friedel D, Hinz FE, Mahlknecht PD, Schinkewitsch S, Rieder M, Fernandez NR, Stengs L, Chang Y, Ringel A, Haag D, Pusch S, Stichel D, Schrimpf D, Kramm CM, Wesseling P, Schweizer L, Harter P, Hartmann C, Capper D, Snuderl M, Boldt H, Brandner S, Dohmen H, Acker T, Schittenhelm J, Hasselblatt M, Agardy D, Bunse T, Bunse L, Korshunov A, Herold-Mende C, Etminan N, Wick W, Platten M, Das A, Tabori U, Blattner-Johnson M, Sill M, Sturm D, Pfister SM, Jones DTW, Sahm F, von Deimling A, Reuss DE
Reirradiation for Patients With Recurrent Ependymoma Across the Age Spectrum.
Sum YY, Bennett J, Ramaswamy V, Das A, Liu AP, Huang A, Tabori U, Dirks P, Nassiri F, Keilty DM, Tsang DS
The impact of international care networks on the clinical management of constitutional mismatch repair deficiency (CMMRD): a review of recent developments.
Vasen HFA, Wimmer K, van Kouwen M, Guerrini-Rousseau L, Gattini D, Stengs L, Tabori U, Colas C, Das A
Immune checkpoint inhibitor pneumonitis presenting with multifocal nodular opacities.
Escobar NS, Das A, Tabori U, Manson D, Grasemann H
Tumor-derived cell-free DNA detected in cerebrospinal fluid enables minimally invasive profiling of pediatric brain tumors.
Nobre L, Nakano Y, Burns I, Siddaway R, Zápotocky M, Johnson M, Rana M, Li C, Lyn RK, Yuditskiy R, Ku M, Sheth J, Levine AB, Nesvick CL, Das A, Cacciotti C, Zelcer S, Climans SA, MacDonald M, Negm L, Chung J, Bennett J, Bondoc A, Loukides J, Stengs L, Edwards M, Bouffet E, Ramaswamy V, Liu AP, Huang A, Bartels U, Dirks PB, Tabori U, Hawkins C
Pediatric low-grade gliomas; a 12-year retrospective review from a tertiary care hospital in LMIC.
Mushtaq N, Bashir F, Zahid S, Shafique MA, Shahid MM, Rehman A, Minhas K, Anwar SSM, Qureshi BM, Enam SA, Tabori U, Bouffet E
Ultrasound-Enhanced Drug Delivery in Pediatric Neuro-Oncology: A New Therapeutic Strategy.
Weber E, Smith CA, Hawkins C, Tabori U, Dirks PB, Rutka JT
Prior therapy defines mutation profiles in childhood cancer at relapse.
Layeghifard M, Díaz-Gay M, Bergstrom EN, Mahendralingam MJ, Light N, Blay S, Nash JO, Anderson ND, Au JN, Davidson S, Ballester PL, Wen T, Daud SK, Edward LM, Ashiqul Islam SM, Khandekar A, Otlu B, Brunga L, Hammad R, Nassif S, Thacker NH, Feltham T, Fuentes-Bolanos NA, Wong-Erasmus M, Levine MF, Miller KE, Shukla NN, Kinnaman MD, Glodzik D, Portwine C, Millson S, Zorzi AP, Mikhail M, Fernandez CV, Wheaton L, Gundem G, Kung AL, Tabori U, Mayoh C, Papaemmanuil E, Cowley MJ, Malkin D, Villani A, Alexandrov LB, Shlien A
hTERT Expression, Regulation, and Prognostic Significance in Pediatric Medulloblastoma.
Tanaka R, Umaru B, Sobo M, Kumar SS, Dorris K, Hovestadt V, Ramaswamy V, Remke M, Margol A, Stevenson CB, Asgharzadeh S, Goldman S, Miles L, Huang J, von Hoff K, Rutkowski S, Onar-Thomas A, Tabori U, Taylor M, Pfister SM, Salloum R, Fouladi M, Drissi R
Functionally distinct ALK and ROS1 fusions detected in infant-type hemispheric gliomas converge on STAT3 and SHP2 activation.
Postlmayr A, Sanchez Bergman A, Torrejon Diaz J, Ciraulo B, Yan S, Hofmann N, Carbajal S, Dobler R, Machaalani C, Schönholzer MT, Priego Gonzalez L, De Micheli AJ, Berenjeno-Correa E, Baroncini L, Grotzer MA, Tabori U, Hawkins C, Ayrault O, Zuckermann M, Baumgartner M, Guerreiro Stücklin AS
Towards immune based combinations for the treatment of IDH1 mutant replication repair deficient gliomas
Principal investigators: Tabori, Uri
Keywords: Companion Biomarkers; Gliomagenesis; Idh1-Mutant Gliomas; Immune Microenvironment; Immune Vulnerabilities; Immunotherapy Combinations; Immunotherapy Trials; Replication Repair Deficiency
Next generation precision oncology for pediatric-type AYA gliomas
Principal investigators: Hawkins, Cynthia E
Keywords: Aya; Low Grade Glioma; Pediatric Brain Tumor; Precision Medicine; Ras/Mapk Pathway; Single Cell Sequencing
Imaging-based classification and treatment response prediction of pediatric low-grade gliomas for precision child health
Principal investigators: Khalvati, Farzad; Ertl-Wagner, Birgit B
Keywords: Artificial Intelligence; Genetic Marker Prediction; Magnetic Resonance Imaging; Medical Image Analysis; Pediatric Cancer Research; Pediatric Low-Grade Glioma; Precision Child Health; Treatment Response Prediction
Canadian Pediatric Cancer Consortium
Principal investigators: David Malkin, James Whitlock; Co-Dyre, Adrienne; McIntosh, Keith A; Denburg, Avram E; Deyell, Rebecca J; Duval, Michel; Jabado, Nada; Marjerrison, Stacey L; Rayar, Meera; Tsimicalis, Argerie
Keywords: Cancer -Omics; Cancer Modeling; Clinical Trials; Community Engagement; Implementation Science; Innovative Therapies; Knowledge Mobilization; Pan-Canadian Consortium; Pediatric Cancer; Training And Mentorship
A recurrent frameshift neoantigen mRNA vaccine for immunoprevention of replication repair deficient gliomas
Principal investigators: Mazzoli, Vienna
Keywords: Cancer Mrna Vaccine; Cancer Prevention; Hereditary Cancer Syndromes; Replication Repair Deficiency
A phase 2 study of mirdametinib and vinblastine for newly diagnosed or previously untreated patients with pediatric low-grade glioma and activation of the MAPK pathway
Principal investigators: Perreault, Sebastien
Keywords: Clinical Trial
Uncovering the mechanism and impact of novel genetic and epigenetic promoter alterations on tissue-specific mismatch repair deficient cancers
Principal investigators: Tabori, Uri
Keywords: Cancer Predisposition; Colon Cancers; Glioma; Hypermutation; Mismatch Repair Deficiency; Promoter Hypermethylation; Promoter Mutation
Upfront Adaptive Immunotherapy Approach for Hypermutant Glioblastoma in Children, Adolescents and Young Adults
Principal investigators: Bouffet, Eric; Thacker, Nirav H
Keywords: Cancer Biomarkers; Glioblastoma; Hypermutation; Immunotherapy; Prediction Of Response To Immunotherapies
Determining the cellular mechanisms of initiation and evolution of hypermutant glioma
Principal investigators: Dirks, Peter B
Keywords: Brain Cancer; Cancer Initiation And Progression; Dna Repair; Glioblastoma; Human Neural Stem Cells; Mouse Models Of Glioblastoma; Preneoplasia
Training Researchers In the Next generation in Gastroenterology and Liver (TRIANGLE)
Principal investigators: Jones, Nicola L; Bhat, Mamatha; Hirota, Simon A; Kaplan, Gilaad G; Lee, Kate; McKay, Derek M; Otley, Anthony R; Pena-Sanchez, Juan-Nicolas; Perreault, Nathalie; Reynolds, Lisa A; Rose, Christopher; Targownik, Laura E; Vallance, Bruce A; Verdu, Elena F
Keywords: Gastroenterology; Health Research Training Program; Liver
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Pediatrics
- Genetics and Genome Biology
- Neurosciences and Mental Health
- Surgery
- Department of Laboratory Medicine and Pathobiology
- Department of Paediatrics
- Developmental Stem Cell Biology
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Cynthia Hawkins
Department of Laboratory Medicine and Pathobiology
122 shared papers, latest 2026
Eric Bouffet
Department of Paediatrics
117 shared papers, latest 2026
Vijay Ramaswamy
Developmental Stem Cell Biology
80 shared papers, latest 2026
David Malkin
Pediatrics
58 shared papers, latest 2026
Ute Bartels
Faculty
57 shared papers, latest 2026
Annie Huang
Pediatrics
56 shared papers, latest 2026
Adam Shlien
Faculty
29 shared papers, latest 2026
Nada Jabado
Pediatrics
26 shared papers, latest 2026
Farzad Khalvati
Department of Medical Imaging
12 shared papers, latest 2026
Nada Jabado
Faculty
11 shared papers, latest 2017
Livia Garzia
Faculty
9 shared papers, latest 2018
Steven Gallinger
Medical Biophysics
9 shared papers, latest 2025
Valérie Larouche
Pediatric Hematology/Oncology
9 shared papers, latest 2026
Gelareh Zadeh
Neurosurgery
8 shared papers, latest 2025
Rosanna Weksberg
Genetics and Genome Biology
8 shared papers, latest 2025
Sunit Das
Surgery
8 shared papers, latest 2025
Donald Mabbott
Neurosciences and Mental Health
8 shared papers, latest 2024
Birgit Ertl-Wagner
Neurosciences and Mental Health
6 shared papers, latest 2026
Birgit Ertl-Wagner
Biomedical Engineering
6 shared papers, latest 2026
James Rutka
Department of Surgery
6 shared papers, latest 2021
Adam Fleming
Pediatrics
6 shared papers, latest 2026
Boleslaw Lach
Pathology & Molecular Medicine
5 shared papers, latest 2017
Gregory Pond
Oncology
1 shared papers, latest 2016
Paul Gibson
Pediatrics
1 shared papers, latest 2021
Joseph Beyene
Health Research Methods, Evidence, and Impact
1 shared papers, latest 2011
Julianna Sienna
Oncology
1 shared papers, latest 2024
Girish Kulkarni
Toronto General Research Institute
1 shared papers, latest 2019
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