Faculty profile

Valérie Larouche

ResearcherPediatric Hematology/OncologyUniversité Laval

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université Laval directory, so their courses and email address may be missing. Find their university profile.

Valérie Larouche

Researcher

Pediatric Hematology/Oncology

Health Sciences

Université Laval

Quebec City, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
8 publications in the last five years, latest in 2026.
Principal investigator on 1 research grant (1 CIHR), most recently in 2017.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

242

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Neuro-Oncologie Pédiatrique

Latest papers

Integrated clinical and molecular landscape of disseminated pediatric low-grade glioma
Neuro-Oncology · 2026
Disseminated pediatric low-grade glioma and hydrocephalus: a multinational consortium analysis of incidence and mortality.
Journal of Neurosurgery: Pediatrics · 2026
Immune landscape of oncohistone-mutant gliomas reveals diverse myeloid populations and tumor-promoting function.
Nature communications · 2024

All 19 publications

Latest funding

A Phase 2 study of Trametinib for patients with pediatric glioma or plexiform neurofibroma with refractory tumor and activation of the MAPK/ERK pathwa
CIHR · 2019 · Co-investigator
$573,750
Epidemiology of primary pediatric brain tumor in Canada : A 15 years report from a National cancer Registry
CIHR · 2017 · Nominated PI
$15,000
Predicting, preventing, and mitigating late effects in medulloblastoma.
CIHR · 2010 · Co-investigator
$5,000

All 3 grants and awards

19 publications.

Integrated clinical and molecular landscape of disseminated pediatric low-grade glioma

Levine AB, Bennett J, Patil P, Burns I, Siddaway R, Li C, Haizel-Cobbina J, Rana M, Yuditskiy R, Son A

Neuro-Oncology20263 citations

DOI: 10.1093/neuonc/noaf245

Disseminated pediatric low-grade glioma and hydrocephalus: a multinational consortium analysis of incidence and mortality.

Lyons AT, Haizel-Cobbina J, Levine A, Bishay AE, Jew N, Li C, Patil P, Bennett J, Siddaway R, Yuditskiy R

Journal of Neurosurgery: Pediatrics2026

DOI: 10.3171/2025.8.peds25160

Immune landscape of oncohistone-mutant gliomas reveals diverse myeloid populations and tumor-promoting function.

Andrade AF, Annett A, Karimi E, Topouza DG, Rezanejad M, Liu Y, McNicholas M, Gonzalez Santiago EG, Llivichuzhca-Loja D, Gehlhaar A, Jessa S, De Cola A, Chandarana B, Russo C, Faury D, Danieau G, Puligandla E, Wei Y, Zeinieh M, Wu Q, Hebert S, Juretic N, Nakada EM, Krug B, Larouche V, Weil AG, Dudley RWR, Karamchandani J, Agnihotri S, Quail DF, Ellezam B, Konnikova L, Walsh LA, Pathania M, Kleinman CL, Jabado N

Nature communications2024

DOI: 10.1038/s41467-024-52096-w PMID: 39237515

Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study.

Ercan AB, Aronson M, Fernandez NR, Chang Y, Levine A, Liu ZA, Negm L, Edwards M, Bianchi V, Stengs L, Chung J, Al-Battashi A, Reschke A, Lion A, Ahmad A, Lassaletta A, Reddy AT, Al-Darraji AF, Shah AC, Van Damme A, Bendel A, Rashid A, Margol AS, Kelly BL, Pencheva B, Heald B, Lemieux-Anglin B, Crooks B, Koschmann C, Gilpin C, Porter CC, Gass D, Samuel D, Ziegler DS, Blumenthal DT, Kuo DJ, Hamideh D, Basel D, Khuong-Quang DA, Stearns D, Opocher E, Carceller F, Baris Feldman H, Toledano H, Winer I, Scheers I, Fedorakova I, Su JM, Vengoechea J, Sterba J, Knipstein J, Hansford JR, Gonzales-Santos JR, Bhatia K, Bielamowicz KJ, Minhas K, Nichols KE, Cole KA, Penney L, Hjort MA, Sabel M, Gil-da-Costa MJ, Murray MJ, Miller M, Blundell ML, Massimino M, Al-Hussaini M, Al-Jadiry MF, Comito MA, Osborn M, Link MP, Zapotocky M, Ghalibafian M, Shaheen N, Mushtaq N, Waespe N, Hijiya N, Fuentes-Bolanos N, Ahmad O, Chamdine O, Roy P, Pichurin PN, Nyman P, Pearlman R, Auer RC, Sukumaran RK, Kebudi R, Dvir R, Raphael R, Elhasid R, McGee RB, Chami R, Noss R, Tanaka R, Raskin S, Sen S, Lindhorst S, Perreault S, Caspi S, Riaz S, Constantini S, Albert S, Chaleff S, Bielack S, Chiaravalli S, Cramer SL, Roy S, Cahn S, Penna S, Hamid SA, Ghafoor T, Imam U, Larouche V, Magimairajan Issai V, Foulkes WD, Lee YY, Nathan PC, Maruvka YE, Greer MC, Durno C, Shlien A, Ertl-Wagner B, Villani A, Malkin D, Hawkins C, Bouffet E, Das A, Tabori U

The Lancet. Oncology2024

DOI: 10.1016/s1470-2045(24)00026-3 PMID: 38552658

Combined Immunotherapy Improves Outcome for Replication-Repair-Deficient (RRD) High-Grade Glioma Failing Anti-PD-1 Monotherapy: A Report from the International RRD Consortium.

Das A, Fernandez NR, Levine A, Bianchi V, Stengs LK, Chung J, Negm L, Dimayacyac JR, Chang Y, Nobre L, Ercan AB, Sanchez-Ramirez S, Sudhaman S, Edwards M, Larouche V, Samuel D, Van Damme A, Gass D, Ziegler DS, Bielack SS, Koschmann C, Zelcer S, Yalon-Oren M, Campino GA, Sarosiek T, Nichols KE, Loret De Mola R, Bielamowicz K, Sabel M, Frojd CA, Wood MD, Glover JM, Lee YY, Vanan M, Adamski JK, Perreault S, Chamdine O, Hjort MA, Zapotocky M, Carceller F, Wright E, Fedorakova I, Lossos A, Tanaka R, Osborn M, Blumenthal DT, Aronson M, Bartels U, Huang A, Ramaswamy V, Malkin D, Shlien A, Villani A, Dirks PB, Pugh TJ, Getz G, Maruvka YE, Tsang DS, Ertl-Wagner B, Hawkins C, Bouffet E, Morgenstern DA, Tabori U

Cancer discovery2024

DOI: 10.1158/2159-8290.cd-23-0559 PMID: 37823831

Germline Platelet-derived growth factor receptor beta p.R987W pathogenic variant in 2 children with brain tumors.

Han H, Renzi S, Larouche V, Faury D, Langlois S, Sinnett D, Gomez A, Karamchandani J, Crevier L, Foulkes WD, Jabado N

Neuro-oncology advances2023

DOI: 10.1093/noajnl/vdad029 PMID: 37114246

Characteristics of patients ≥10 years of age with diffuse intrinsic pontine glioma: a report from the International DIPG/DMG Registry.

Erker C, Lane A, Chaney B, Leary S, Minturn JE, Bartels U, Packer RJ, Dorris K, Gottardo NG, Warren KE, Broniscer A, Kieran MW, Zhu X, White P, Dexheimer PJ, Black K, Asher A, DeWire M, Hansford JR, Gururangan S, Nazarian J, Ziegler DS, Sandler E, Bartlett A, Goldman S, Shih CS, Hassall T, Dholaria H, Bandopadhayay P, Samson Y, Monje M, Fisher PG, Dodgshun A, Parkin S, Chintagumpala M, Tsui K, Gass D, Larouche V, Broxson E, Garcia Lombardi M, Wang SS, Ma J, Hawkins C, Hamideh D, Wagner L, Koschmann C, Fuller C, Drissi R, Jones BV, Leach J, Fouladi M

Neuro-oncology2022

DOI: 10.1093/neuonc/noab140 PMID: 34114629

Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency.

Das A, Sudhaman S, Morgenstern D, Coblentz A, Chung J, Stone SC, Alsafwani N, Liu ZA, Karsaneh OAA, Soleimani S, Ladany H, Chen D, Zatzman M, Cabric V, Nobre L, Bianchi V, Edwards M, Sambira Nahum LC, Ercan AB, Nabbi A, Constantini S, Dvir R, Yalon-Oren M, Campino GA, Caspi S, Larouche V, Reddy A, Osborn M, Mason G, Lindhorst S, Bronsema A, Magimairajan V, Opocher E, De Mola RL, Sabel M, Frojd C, Sumerauer D, Samuel D, Cole K, Chiaravalli S, Massimino M, Tomboc P, Ziegler DS, George B, Van Damme A, Hijiya N, Gass D, McGee RB, Mordechai O, Bowers DC, Laetsch TW, Lossos A, Blumenthal DT, Sarosiek T, Yen LY, Knipstein J, Bendel A, Hoffman LM, Luna-Fineman S, Zimmermann S, Scheers I, Nichols KE, Zapotocky M, Hansford JR, Maris JM, Dirks P, Taylor MD, Kulkarni AV, Shroff M, Tsang DS, Villani A, Xu W, Aronson M, Durno C, Shlien A, Malkin D, Getz G, Maruvka YE, Ohashi PS, Hawkins C, Pugh TJ, Bouffet E, Tabori U

Nature medicine2022

DOI: 10.1038/s41591-021-01581-6 PMID: 34992263

Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance.

Durno C, Ercan AB, Bianchi V, Edwards M, Aronson M, Galati M, Atenafu EG, Abebe-Campino G, Al-Battashi A, Alharbi M, Azad VF, Baris HN, Basel D, Bedgood R, Bendel A, Ben-Shachar S, Blumenthal DT, Blundell M, Bornhorst M, Bronsema A, Cairney E, Rhode S, Caspi S, Chamdin A, Chiaravalli S, Constantini S, Crooks B, Das A, Dvir R, Farah R, Foulkes WD, Frenkel Z, Gallinger B, Gardner S, Gass D, Ghalibafian M, Gilpin C, Goldberg Y, Goudie C, Hamid SA, Hampel H, Hansford JR, Harlos C, Hijiya N, Hsu S, Kamihara J, Kebudi R, Knipstein J, Koschmann C, Kratz C, Larouche V, Lassaletta A, Lindhorst S, Ling SC, Link MP, Loret De Mola R, Luiten R, Lurye M, Maciaszek JL, MagimairajanIssai V, Maher OM, Massimino M, McGee RB, Mushtaq N, Mason G, Newmark M, Nicholas G, Nichols KE, Nicolaides T, Opocher E, Osborn M, Oshrine B, Pearlman R, Pettee D, Rapp J, Rashid M, Reddy A, Reichman L, Remke M, Robbins G, Roy S, Sabel M, Samuel D, Scheers I, Schneider KW, Sen S, Stearns D, Sumerauer D, Swallow C, Taylor L, Thomas G, Toledano H, Tomboc P, Van Damme A, Winer I, Yalon M, Yen LY, Zapotocky M, Zelcer S, Ziegler DS, Zimmermann S, Hawkins C, Malkin D, Bouffet E, Villani A, Tabori U

Journal of clinical oncology : official journal of the American Society of Clinical Oncology2021

DOI: 10.1200/jco.20.02636 PMID: 33945292

Screening for asymptomatic diabetes and metabolic comorbidities in pediatric patients during therapy for acute lymphoblastic leukemia.

Larouche V, Bellavance C, Tibout P, Bergeron S, Simonyan D, Gagné J

Journal of pediatric endocrinology & metabolism : JPEM2021First author

DOI: 10.1515/jpem-2020-0457 PMID: 33838097

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Valérie Larouche

Research

Latest papers

Latest funding

Integrated clinical and molecular landscape of disseminated pediatric low-grade glioma

Disseminated pediatric low-grade glioma and hydrocephalus: a multinational consortium analysis of incidence and mortality.

Immune landscape of oncohistone-mutant gliomas reveals diverse myeloid populations and tumor-promoting function.

Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study.

Combined Immunotherapy Improves Outcome for Replication-Repair-Deficient (RRD) High-Grade Glioma Failing Anti-PD-1 Monotherapy: A Report from the International RRD Consortium.

Germline Platelet-derived growth factor receptor beta p.R987W pathogenic variant in 2 children with brain tumors.

Characteristics of patients &#x2265;10 years of age with diffuse intrinsic pontine glioma: a report from the International DIPG/DMG Registry.

Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency.

Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance.

Screening for asymptomatic diabetes and metabolic comorbidities in pediatric patients during therapy for acute lymphoblastic leukemia.

A Phase 2 study of Trametinib for patients with pediatric glioma or plexiform neurofibroma with refractory tumor and activation of the MAPK/ERK pathwa

Epidemiology of primary pediatric brain tumor in Canada : A 15 years report from a National cancer Registry

Predicting, preventing, and mitigating late effects in medulloblastoma.

Frequent collaborators

Eric Bouffet

Uri Tabori

Cynthia Hawkins

Adam Fleming

Nada Jabado

David Malkin

Adam Shlien

Ute Bartels

Sebastien Perreault

Vijay Ramaswamy

Annie Huang

Jason Karamchandani

Daniel Sinnett

Birgit Ertl-Wagner

Birgit Ertl-Wagner

Catherine Goudie

Jason Karamchandani

Carol Swallow

Livia Garzia

Lili-Naz Hazrati

Sonia Cellot

Corina Nagy

Daniel Morgenstern

Donna Johnston

Gino Somers

Wei Xu

Paul Gibson

James Rutka

Santiago Costantino

Gustavo Turecki

Santiago Costantino

Nandini Dendukuri

Guillaume Bourque

Characteristics of patients ≥10 years of age with diffuse intrinsic pontine glioma: a report from the International DIPG/DMG Registry.