Faculty profile

David Malkin

ResearcherPediatricsUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.

David Malkin

Researcher

Pediatrics

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
86 publications in the last five years, latest in 2026.
Senior (last) author on 12 recent papers, a sign of leading a research group.
Principal investigator on 10 research grants (10 CIHR), most recently in 2024.
Supervised 10 trainees who won CIHR awards, most recently in 2026.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

258

Publications

3,134

Citations

h-index

127

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

Search on Google Scholar

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Signals and details

Research

Li-Fraumeni Syndrome P53 Cancer Predisposition Epigenetics Genetic Modifiers Access To Innovative Therapies & Optimal Care Cancer Biology Clinical Trials

Latest papers

Future Trends in Cancer Prevention and Interception in Cancer Predisposition Syndromes: Leveraging Insights From High-Risk Populations.
International journal of cancer · 2026
Family experiences of receiving treatment recommendations in a precision medicine trial for poor-prognosis childhood cancer.
NPJ genomic medicine · 2026
Digital Health Tools Embedded in a Cancer Genetics Clinic: Observational Study.
JMIR formative research · 2026

All 258 publications

Latest funding

Communicating Genetic Risk in Childhood Cancer: Timing, Knowledge, and Long-Term Implications
CIHR · 2026 · Supervisor
$6,000
Mapping Loss of Heterozygosity in Li-Fraumeni Syndrome to Uncover Early Molecular Drivers of Tumorigenesis
CIHR · 2025 · Supervisor
$120,000
Towards patient-centred precision oncology care for children and youth: Understanding psychosocial impacts and experiences through patient and professional perspectives
CIHR · 2024 · Co-investigator
$1,013,626

All 31 grants and awards

From the 150 most recent of 258 publications.

Future Trends in Cancer Prevention and Interception in Cancer Predisposition Syndromes: Leveraging Insights From High-Risk Populations.

Wang Y, Malkin D, Lipkin SM

International journal of cancer2026

DOI: 10.1002/ijc.70674 PMID: 42538617

Family experiences of receiving treatment recommendations in a precision medicine trial for poor-prognosis childhood cancer.

Hetherington K, Hunter JD, Donoghoe MW, McGillycuddy M, McGill BC, Robertson EG, Tyrrell V, Lau LMS, Marron JM, Tucker KM, Marshall GM, Vetsch J, Haber M, Malkin D, Mateos MK, O'Brien TA, Ziegler DS, Wakefield CE

NPJ genomic medicine2026

DOI: 10.1038/s41525-026-00591-y PMID: 42399266

Digital Health Tools Embedded in a Cancer Genetics Clinic: Observational Study.

Nagaraj S, Rabinowicz R, Goodday S, Brunga L, Korenblum C, Villani A, Kim R, Karlin E, Greer RW, Balaci H, Omran M, Goldenberg A, Malkin D, Friend S

JMIR formative research2026

DOI: 10.2196/74375 PMID: 41627862

Patterns of hypermutation shape tumorigenesis and immunotherapy response in mismatch-repair-deficient glioma.

Fernandez NR, Chang Y, Nunes NM, Dimayacyac JR, Levine A, Ringel A, Negm L, Ercan AB, Hess JM, Ahmad O, Lee C, Stengs L, Bianchi V, Edwards M, Doherty S, Chung J, Nobre L, Bennett J, Dodgshun AJ, Jones DTW, Pfister SM, Villani A, Malkin D, Ramaswamy V, Huang A, Bouffet E, Aronson M, Dirks PB, Shlien A, Getz G, Maruvka YE, Ertl-Wagner B, Hawkins C, Das A, Tabori U

Nature genetics2026

DOI: 10.1038/s41588-025-02420-x PMID: 41430480

Cancer Predisposition Syndromes in Children: Who, When, and How to Screen?

Fung KFK, Rutten C, Villani A, Pai VB, Kan EY, Laughlin S, Chiu YT, Marie E, Ertl-Wagner B, Malkin D, Voss SD, States LJ, Doria AS, Greer MC

Radiographics : a review publication of the Radiological Society of North America, Inc2026

DOI: 10.1148/rg.260022 PMID: 42784470

Prior therapy defines mutation profiles in childhood cancer at relapse.

Layeghifard M, Díaz-Gay M, Bergstrom EN, Mahendralingam MJ, Light N, Blay S, Nash JO, Anderson ND, Au JN, Davidson S, Ballester PL, Wen T, Daud SK, Edward LM, Ashiqul Islam SM, Khandekar A, Otlu B, Brunga L, Hammad R, Nassif S, Thacker NH, Feltham T, Fuentes-Bolanos NA, Wong-Erasmus M, Levine MF, Miller KE, Shukla NN, Kinnaman MD, Glodzik D, Portwine C, Millson S, Zorzi AP, Mikhail M, Fernandez CV, Wheaton L, Gundem G, Kung AL, Tabori U, Mayoh C, Papaemmanuil E, Cowley MJ, Malkin D, Villani A, Alexandrov LB, Shlien A

Nature2026

DOI: 10.1038/s41586-026-10803-1 PMID: 42486975

Childhood cancer predisposition study: a prospective registry and biorepository protocol.

Perrino MR, MacFarland SP, Maese L, Vagher J, Kamihara J, Rednam S, Lupo PJ, Brodeur GM, Schiffman J, Diller L, Desrosiers-Battu L, Plon SE, Nichols KE, Volchenboum SL, Malkin D, Villani A, Porter CC

BMJ open2026

DOI: 10.1136/bmjopen-2026-120576 PMID: 42556843

Non-invasive screening in hereditary cancer: a randomized controlled trial to test cell-free DNA-based early detection in the CHARM consortium

Farncombe KM, Sobotka JA, Aronson M, Basik M, Bombard Y, Born L, Cheifetz R, Clausen M, Coburn N, Dawson L

European Journal of Human Genetics20263 citations

DOI: 10.1038/s41431-026-02014-z

The legacy of a gentleman scientist: Pierre Hainaut

Arnoult C, Attardi LD, Batsheva K, Blandino G, Burns KH, Del Sal G, Kirsch DG, Lane DP, Levine AJ, Lozano G

Cell Death and Differentiation2026

DOI: 10.1038/s41418-025-01586-5

Detecting and Remediating Harmful Data Shifts for the Responsible Deployment of Clinical AI Models.

Subasri V, Krishnan A, Kore A, Dhalla A, Pandya D, Wang B, Malkin D, Razak F, Verma AA, Goldenberg A, Dolatabadi E

JAMA network open2025

DOI: 10.1001/jamanetworkopen.2025.13685 PMID: 40465297

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David Malkin

Research

Latest papers

Latest funding

Future Trends in Cancer Prevention and Interception in Cancer Predisposition Syndromes: Leveraging Insights From High-Risk Populations.

Family experiences of receiving treatment recommendations in a precision medicine trial for poor-prognosis childhood cancer.

Digital Health Tools Embedded in a Cancer Genetics Clinic: Observational Study.

Patterns of hypermutation shape tumorigenesis and immunotherapy response in mismatch-repair-deficient glioma.

Cancer Predisposition Syndromes in Children: Who, When, and How to Screen?

Prior therapy defines mutation profiles in childhood cancer at relapse.

Childhood cancer predisposition study: a prospective registry and biorepository protocol.

Non-invasive screening in hereditary cancer: a randomized controlled trial to test cell-free DNA-based early detection in the CHARM consortium

The legacy of a gentleman scientist: Pierre Hainaut

Detecting and Remediating Harmful Data Shifts for the Responsible Deployment of Clinical AI Models.

Frequent collaborators

Uri Tabori

Adam Shlien

Eric Bouffet

Cynthia Hawkins

Vijay Ramaswamy

Annie Huang

Nada Jabado

Catherine Goudie

Anna Goldenberg

Adam Fleming

Ute Bartels

Rosanna Weksberg

James Rutka

Livia Garzia

Birgit Ertl-Wagner

Valérie Larouche

Livia Garzia

Birgit Ertl-Wagner

Nada Jabado

Steven Gallinger

Gelareh Zadeh

Xi Huang

Johann Hitzler

Donna Johnston

Yvonne Bombard

Wei Xu

Boleslaw Lach

Paul Gibson

Michael Brudno

Donald Mabbott

David Chitayat

Michael Taylor

Mathieu Lupien

Sevan Hopyan

Fang Liu

Bartha Knoppers

Michael Sullivan

Joseph Beyene

Michael Ohh

Sheila Singh