Faculty profile
Vijay Shahani
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Research
Latest papers
Next-generation bromodomain inhibitors of the SWI/SNF complex enhance DNA damage and cell death in glioblastoma.
Journal of cellular and molecular medicine · 2023
Discovery of a Novel DCAF1 Ligand Using a Drug-Target Interaction Prediction Model: Generalizing Machine Learning to New Drug Targets.
Journal of chemical information and modeling · 2023
Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease.
Scientific reports · 2021
Latest funding
- $35,000
Translating the pathophysiological details of diabetes mellitus, including the molecular function of Sulfonylureas drugs in the treatment of the disease state, into accessible visualizations for patients and non-patients to increase disease understanding and motivate citizens to adopt improved diets, exercise regimens and better prescription drug adherence practices.
CIHR · 2013 · Nominated PI
4 publications.
Next-generation bromodomain inhibitors of the SWI/SNF complex enhance DNA damage and cell death in glioblastoma.
Yang C, He Y, Wang Y, McKinnon PJ, Shahani V, Miller DD, Pfeffer LM
Discovery of a Novel DCAF1 Ligand Using a Drug-Target Interaction Prediction Model: Generalizing Machine Learning to New Drug Targets.
Kimani SW, Owen J, Green SR, Li F, Li Y, Dong A, Brown PJ, Ackloo S, Kuter D, Yang C, MacAskill M, MacKinnon SS, Arrowsmith CH, Schapira M, Shahani V, Halabelian L
Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease.
Sugiyama MG, Cui H, Redka DS, Karimzadeh M, Rujas E, Maan H, Hayat S, Cheung K, Misra R, McPhee JB, Viirre RD, Haller A, Botelho RJ, Karshafian R, Sabatinos SA, Fairn GD, Madani Tonekaboni SA, Windemuth A, Julien JP, Shahani V, MacKinnon SS, Wang B, Antonescu CN
Genetic Variability of the SARS-CoV-2 Pocketome.
Yazdani S, De Maio N, Ding Y, Shahani V, Goldman N, Schapira M
Translating the pathophysiological details of diabetes mellitus, including the molecular function of Sulfonylureas drugs in the treatment of the disease state, into accessible visualizations for patients and non-patients to increase disease understanding and motivate citizens to adopt improved diets, exercise regimens and better prescription drug adherence practices.
Principal investigators: Shahani, Vijay M
Keywords: Atherosclerosis; Cardiovascular Disease; Diabetes Mellitus; Health Communication; Health Education; Information Technology; Molecular Imaging; Public Health And Outreach; Sulfonylureas; Visualization
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Vijay Shahani and Matthieu Schapira: 2 shared papers
- Vijay Shahani and Jean-Philippe Julien: 1 shared paper
- Vijay Shahani and BO WANG: 1 shared paper
- Jean-Philippe Julien and BO WANG: 1 shared paper
- Biomedical Communications
- Structural Genomics Consortium
- Department of Biochemistry
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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