Faculty profile

Vincent Tropepe

ResearcherDepartment of Cell & Systems BiologyUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses may be missing. Find their university profile.

Vincent Tropepe

Researcher

Department of Cell & Systems Biology

Faculty of Arts and Science

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
5 publications in the last five years, latest in 2026.
Senior (last) author on 4 recent papers, a sign of leading a research group.
Principal investigator on 7 research grants (5 NSERC, 2 CIHR), most recently in 2022.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Neurogenesis Zebrafish Brain Development Epigenetics Plasticity Sensory Stem cells

Latest papers

CFAP20 salvages arrested RNAPII from the path of co-directional replisomes.
Nature · 2026
The homeobox gene, dmbx1a, is required for the development and maintenance of bipolar and photoreceptor cells in the zebrafish retina.
Experimental eye research · 2026 · senior author
Overlapping expression and co-operative function of the zebrafish pcdh15 paralogs.
Communications biology · 2026 · senior author

All 43 publications

Latest funding

Neurogenic plasticity and brain development
NSERC · 2022 · Principal investigator
$120,000
The molecular basis of Müller cell dedifferentiation during retinal regeneration
CIHR · 2020 · Nominated PI
$504,900
Neurogenic plasticity and brain development
NSERC · 2016 · Principal investigator
$228,000

All 18 grants and awards

43 publications.

CFAP20 salvages arrested RNAPII from the path of co-directional replisomes.

Uruci S, Boer DEC, Chrystal PW, Lalonde M, Panagopoulos A, Yakoub G, Kirdök I, de Lint K, van der Woude M, Wendel TJ, Brussee SJ, Wondergem AP, van Overbeek NK, Schotman N, Lingeman J, Ljungman M, van Oudenaarden A, van Attikum H, Vertegaal ACO, Noordermeer SM, Wolthuis RMF, Altmeyer M, Hamperl S, Tropepe V, van den Berg J, van den Heuvel D, Luijsterburg MS

Nature2026

DOI: 10.1038/s41586-025-09943-7 PMID: 41535461

The homeobox gene, dmbx1a, is required for the development and maintenance of bipolar and photoreceptor cells in the zebrafish retina.

Miles A, Stulberg J, Tropepe V

Experimental eye research2026Senior author

DOI: 10.1016/j.exer.2025.110809 PMID: 41422989

Overlapping expression and co-operative function of the zebrafish pcdh15 paralogs.

Chrystal PW, Kuzmanova L, Liu J, Izvorean A, Majeed I, Tjoenardi JF, Lin Q, Tropepe V

Communications biology2026Senior author

DOI: 10.1038/s42003-026-10289-7 PMID: 42151386

Darpp-32 is regulated by dopamine and is required for the formation of GABAergic neurons in the developing telencephalon.

Souza BR, Codo BC, Romano-Silva MA, Tropepe V

Progress in neuro-psychopharmacology & biological psychiatry2024Senior author

DOI: 10.1016/j.pnpbp.2024.111060 PMID: 38906412

In Situ Quantification and Isolation of Müller Glial Cells by Fluorescence-Activated Cell Sorting from the Regenerating Larval Zebrafish Retina.

Stulberg J, Tropepe V

Methods in molecular biology (Clifton, N.J.)2022Senior author

DOI: 10.1007/978-1-0716-1979-7_22 PMID: 35507172

Usher syndrome type 1-associated gene, pcdh15b, is required for photoreceptor structural integrity in zebrafish.

Miles A, Blair C, Emili A, Tropepe V

Disease models & mechanisms2021Senior author

DOI: 10.1242/dmm.048965 PMID: 34668518

Know thy neighbor: Modeling spatiotemporal cell-fate patterns in a neural stem cell niche.

Mattocks M, Tropepe V

Cell stem cell2021Senior author

DOI: 10.1016/j.stem.2021.07.005 PMID: 34358437

Retinal Stem Cell 'Retirement Plans': Growth, Regulation and Species Adaptations in the Retinal Ciliary Marginal Zone.

Miles A, Tropepe V

International journal of molecular sciences2021Senior author

DOI: 10.3390/ijms22126528 PMID: 34207050

A reference map of the human binary protein interactome.

Luck K, Kim DK, Lambourne L, Spirohn K, Begg BE, Bian W, Brignall R, Cafarelli T, Campos-Laborie FJ, Charloteaux B, Choi D, Coté AG, Daley M, Deimling S, Desbuleux A, Dricot A, Gebbia M, Hardy MF, Kishore N, Knapp JJ, Kovács IA, Lemmens I, Mee MW, Mellor JC, Pollis C, Pons C, Richardson AD, Schlabach S, Teeking B, Yadav A, Babor M, Balcha D, Basha O, Bowman-Colin C, Chin SF, Choi SG, Colabella C, Coppin G, D'Amata C, De Ridder D, De Rouck S, Duran-Frigola M, Ennajdaoui H, Goebels F, Goehring L, Gopal A, Haddad G, Hatchi E, Helmy M, Jacob Y, Kassa Y, Landini S, Li R, van Lieshout N, MacWilliams A, Markey D, Paulson JN, Rangarajan S, Rasla J, Rayhan A, Rolland T, San-Miguel A, Shen Y, Sheykhkarimli D, Sheynkman GM, Simonovsky E, Taşan M, Tejeda A, Tropepe V, Twizere JC, Wang Y, Weatheritt RJ, Weile J, Xia Y, Yang X, Yeger-Lotem E, Zhong Q, Aloy P, Bader GD, De Las Rivas J, Gaudet S, Hao T, Rak J, Tavernier J, Hill DE, Vidal M, Roth FP, Calderwood MA

Nature2020

DOI: 10.1038/s41586-020-2188-x PMID: 32296183

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

Wolf EJ, Miles A, Lee ES, Nabeel-Shah S, Greenblatt JF, Palazzo AF, Tropepe V, Emili A

Cell reports2020

DOI: 10.1016/j.celrep.2020.107693 PMID: 32460013

Neurogenic plasticity and brain development

Principal investigatorNSERC2022Discovery Grants Program - Individual

Principal investigators: Tropepe, Vincent

Keywords: brain; neurogenesis; zebrafish; epigenetics; development; plasticity; sensory; stem cells

$120,000

The molecular basis of Müller cell dedifferentiation during retinal regeneration

Nominated PICIHR2020Project Grant

Principal investigators: Tropepe, Vincent

Keywords: Clipseq; Gene Editing; Neurogenesis; Regeneration; Retina; Stem Cell; Transgenic; Wound Repair; Zebrafish

$504,900

Neurogenic plasticity and brain development

Principal investigatorNSERC2016Discovery Grants Program - Individual

Principal investigators: Tropepe, Vincent

$228,000

Gel documentation system for multi-user facility

Co-investigatorNSERC2012Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Bruce, Ashley

$16,090

Laser replacements and upgrades for a multi-user spinning disk confocal microscope

Co-investigatorNSERC2011Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Harris, Tony

$92,523

Molecular regulation of progenitor cell behaviour in the developing retina

Nominated PICIHR2011Operating Grant

Principal investigators: Tropepe, Vincent

Keywords: Cell Cycle; Cell Fate; Development; Gene Expression; Genetics; Neurogenesis; Progenitor Cell; Retina; Signaling; Zebrafish

$676,715

Fluorescence stereomicroscope for molecular embryology research

Principal investigatorNSERC2011Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Tropepe, Vincent

$46,947

Structure and plasticity of adult neurogenesis

Principal investigatorNSERC2011Discovery Grants Program - Individual

Principal investigators: Tropepe, Vincent

$150,000

High-speed centrifuge for multi-user molecular core facility

Co-investigatorNSERC2009Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Godt, Dorothea

$36,711

Canadian resource center for zebrafish genetics

Co-investigatorNSERC2009Major Resources Support Program - Infrastructure

Principal investigators: Ekker, Marc

$443,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Vincent Tropepe

Research

Latest papers

Latest funding

CFAP20 salvages arrested RNAPII from the path of co-directional replisomes.

The homeobox gene, dmbx1a, is required for the development and maintenance of bipolar and photoreceptor cells in the zebrafish retina.

Overlapping expression and co-operative function of the zebrafish pcdh15 paralogs.

Darpp-32 is regulated by dopamine and is required for the formation of GABAergic neurons in the developing telencephalon.

In Situ Quantification and Isolation of M&#xfc;ller Glial Cells by Fluorescence-Activated Cell Sorting from the Regenerating Larval Zebrafish Retina.

Usher syndrome type 1-associated gene, pcdh15b, is required for photoreceptor structural integrity in zebrafish.

Know thy neighbor: Modeling spatiotemporal cell-fate patterns in a neural stem cell niche.

Retinal Stem Cell 'Retirement Plans': Growth, Regulation and Species Adaptations in the Retinal Ciliary Marginal Zone.

A reference map of the human binary protein interactome.

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

Neurogenic plasticity and brain development

The molecular basis of Müller cell dedifferentiation during retinal regeneration

Neurogenic plasticity and brain development

Gel documentation system for multi-user facility

Laser replacements and upgrades for a multi-user spinning disk confocal microscope

Molecular regulation of progenitor cell behaviour in the developing retina

Fluorescence stereomicroscope for molecular embryology research

Structure and plasticity of adult neurogenesis

High-speed centrifuge for multi-user molecular core facility

Canadian resource center for zebrafish genetics

Frequent collaborators

Andrew Emili

Zhaolei Zhang

Xiao-Yan Wen

Tod Thiele

Yu Xia

Qian Lin

Ian Scott

Janusz Rak

Peng Huang

Marc Ekker

Brian Ciruna

Jacek Majewski

Sarah McFarlane

Sarah Childs

Joanna Wilson

Rhain Louis

In Situ Quantification and Isolation of Müller Glial Cells by Fluorescence-Activated Cell Sorting from the Regenerating Larval Zebrafish Retina.