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Research
Latest papers
DPCD is a regulator of R2TP in ciliogenesis initiation through Akt signaling.
Cell reports · 2024
Comparative Super-Resolution Mapping of Basal Feet Reveals a Modular but Distinct Architecture in Primary and Motile Cilia.
Developmental cell · 2020 · senior author
Super-Resolution Microscopy and FIB-SEM Imaging Reveal Parental Centriole-Derived, Hybrid Cilium in Mammalian Multiciliated Cells.
Developmental cell · 2020 · senior author
Latest funding
- $650,250
The cellular mechanisms underlying sensory motile ciliopathies
CIHR · 2017 · Nominated PI
- $75,000
Sensory Cilia Mutations Affecting Motile Cilia in Ciliopathy Disorders
CIHR · 2017 · Nominated PI
- $140,000
Structural Engineering Principles of Centrosome Assembly by Super Resolution Microscopy Imaging
NSERC · 2015 · Principal investigator
13 publications.
DPCD is a regulator of R2TP in ciliogenesis initiation through Akt signaling.
Mao YQ, Seraphim TV, Wan Y, Wu R, Coyaud E, Bin Munim M, Mollica A, Laurent E, Babu M, Mennella V, Raught B, Houry WA
Comparative Super-Resolution Mapping of Basal Feet Reveals a Modular but Distinct Architecture in Primary and Motile Cilia.
Nguyen QPH, Liu Z, Albulescu A, Ouyang H, Zlock L, Coyaud E, Laurent E, Finkbeiner W, Moraes TJ, Raught B, Mennella V
Super-Resolution Microscopy and FIB-SEM Imaging Reveal Parental Centriole-Derived, Hybrid Cilium in Mammalian Multiciliated Cells.
Liu Z, Nguyen QPH, Nanjundappa R, Delgehyr N, Megherbi A, Doherty R, Thompson J, Jackson C, Albulescu A, Heng YM, Lucas JS, Dell SD, Meunier A, Czymmek K, Mahjoub MR, Mennella V
A quantitative super-resolution imaging toolbox for diagnosis of motile ciliopathies.
Liu Z, Nguyen QPH, Guan Q, Albulescu A, Erdman L, Mahdaviyeh Y, Kang J, Ouyang H, Hegele RG, Moraes T, Goldenberg A, Dell SD, Mennella V
Quantitative High-Speed Video Profiling Discriminates between DNAH11 and HYDIN Variants of Primary Ciliary Dyskinesia.
Chioccioli M, Feriani L, Nguyen Q, Kotar J, Dell SD, Mennella V, Amirav I, Cicuta P
PPP1R35 is a novel centrosomal protein that regulates centriole length in concert with the microcephaly protein RTTN.
Sydor AM, Coyaud E, Rovelli C, Laurent E, Liu H, Raught B, Mennella V
Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death.
Wong KS, Mabanglo MF, Seraphim TV, Mollica A, Mao YQ, Rizzolo K, Leung E, Moutaoufik MT, Hoell L, Phanse S, Goodreid J, Barbosa LRS, Ramos CHI, Babu M, Mennella V, Batey RA, Schimmer AD, Houry WA
Author Correction: A novel atypical sperm centriole is functional during human fertilization.
Fishman EL, Jo K, Nguyen QPH, Kong D, Royfman R, Cekic AR, Khanal S, Miller AL, Simerly C, Schatten G, Loncarek J, Mennella V, Avidor-Reiss T
A novel atypical sperm centriole is functional during human fertilization.
Fishman EL, Jo K, Nguyen QPH, Kong D, Royfman R, Cekic AR, Khanal S, Miller AL, Simerly C, Schatten G, Loncarek J, Mennella V, Avidor-Reiss T
Centriole Remodeling during Spermiogenesis in Drosophila.
Khire A, Jo KH, Kong D, Akhshi T, Blachon S, Cekic AR, Hynek S, Ha A, Loncarek J, Mennella V, Avidor-Reiss T
The cellular mechanisms underlying sensory motile ciliopathies
Principal investigators: Mennella, Vito
Keywords: Centrosome; Cilia; Ciliopathies; Primary Ciliary Dyskinesia; Super Resolution Microscopy
Sensory Cilia Mutations Affecting Motile Cilia in Ciliopathy Disorders
Principal investigators: Mennella, Vito
Keywords: Cilia; Ciliopathies; Primary Ciliary Dyskinesia; Retinitis Pigmentosa; Super Resolution Imaging
Structural Engineering Principles of Centrosome Assembly by Super Resolution Microscopy Imaging
Principal investigators: Mennella, Vito
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Cell Biology
- Research Institute
- Chemistry and Biochemistry
- Critical Care Medicine
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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