Yeni Yücel, University of Toronto

Research

Read how they describe their research on their University of Toronto profile.

Latest papers

Intraocular Pressure and Retinal Nerve Fiber Layer Changes in a Microgravity Mouse Model and Relevance to Spaceflight-Associated Neuro-Ocular Syndrome.
Eye and brain · 2025 · senior author
Femtosecond pulsed laser photodynamic therapy activates melanin and eradicates malignant melanoma
Proceedings of the National Academy of Sciences · 2024
Post-traumatic Fungal Keratitis and Endophthalmitis Caused by Coniochaeta Hoffmannii with Late Recurrence following Therapeutic Full-thickness Penetrating Keratoplasty.
Ocular immunology and inflammation · 2023

All 9 publications

Latest funding

Imaging a New ALS Biomarker in the Eye
BRAIN · 2022 · Principal investigator
$125,000
Tracking Nanoparticles with Whole-Animal Imaging and Hyperspectral Microscopy: A Novel Strategy for Identifying Biomarkers and Treating Diabetes
ONTARIO · 2013 · Principal investigator
$397,548
Validation of non-invasive rapid eye movements measurement as screening tool for mild traumatic brain injury
CIHR · 2012 · Co-investigator
$250,140

All 5 grants and awards

9 publications.

01

Intraocular Pressure and Retinal Nerve Fiber Layer Changes in a Microgravity Mouse Model and Relevance to Spaceflight-Associated Neuro-Ocular Syndrome.

Zarrinbakhsh A, Gupta N, Sinha J, Zhou X, Chen S, Khan HM, Navajas EV, Beg MF, Liang Y, Yucel Y

Eye and brain2025Senior authorOpen Access

DOI: 10.2147/eb.s526204 PMID: 41221163

02

Femtosecond pulsed laser photodynamic therapy activates melanin and eradicates malignant melanoma

Layla Pires, Shireen Khattak, Sebastião Pratavieira, Carla Calçada, Renan Arnon Romano, Yeni H. Yücel, Vanderlei Salvador Bagnato, Cristina Kurachi, Brian C. Wilson

Proceedings of the National Academy of Sciences202428 citationsOpen Access

DOI: 10.1073/pnas.2316303121 PMID: 38551838

03

Post-traumatic Fungal Keratitis and Endophthalmitis Caused by Coniochaeta Hoffmannii with Late Recurrence following Therapeutic Full-thickness Penetrating Keratoplasty.

Alsarhani W, Lam PW, Kus JV, Rowsell C, Tsui GK, Tadros M, Fattouh R, Yucel Y, Kertes PJ, Chew HF

Ocular immunology and inflammation20233 citations

DOI: 10.1080/09273948.2022.2048028 PMID: 35404731

04

Impact of cerebral hypoperfusion-reperfusion on optic nerve integrity and visual function in the DBA/2J mouse model of glaucoma.

Fraenkl SA, Simon Q, Yucel Y, Gupta N, Wittwer VV, Frueh BE, Tschanz SA

BMJ open ophthalmology20223 citationsOpen Access

DOI: 10.1136/bmjophth-2022-001078 PMID: 36161839

05

The Use of Optical Coherence Tomography for Gross Examination and Sampling of Fixed Breast Specimens: A Pilot Study.

Faragalla H, Davoudi B, Nofech-Moses N, Yucel Y, Jakate K

Diagnostics (Basel, Switzerland)2022

DOI: 10.3390/diagnostics12092191 PMID: 36140591

06

Lymphatic vessels identified in failed corneal transplants with neovascularisation

Diamond MA, Chan SWS, Zhou X, Glinka Y, Girard E, Yucel Y, Gupta N

British Journal of Ophthalmology201918 citationsOpen Access

DOI: 10.1136/bjophthalmol-2018-312630

07

Author Response: The "Ocular Glymphatic System": An Important Missing Piece in the Puzzle of Optic Disc Edema in Astronauts?

Yucel Y, Mathieu E, Gupta N

Investigative ophthalmology & visual science20181 citationsFirst authorOpen Access

DOI: 10.1167/iovs.17-23407 PMID: 29677372

08

Lymphatic drainage from the eye: A new target for therapy.

Yucel Y, Gupta N

Progress in brain research201535 citationsFirst author

DOI: 10.1016/bs.pbr.2015.07.028 PMID: 26497791

09

Increased expression of HIF-1α, nNOS, and VEGF in the cerebral cortex of anemic rats

Anya T. McLaren, Philip A. Marsden, C. David Mazer, Andrew J. Baker, Duncan John Stewart, Albert K.Y. Tsui, Xiaomao Li, Yeni H. Yücel, Malcolm J. Robb, Shelley Romayne Boyd, Elaine Liu, Julie L. Yu, Gregory M. T. Hare

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology2006107 citations

DOI: 10.1152/ajpregu.00403.2006 PMID: 16973934

Imaging a New ALS Biomarker in the Eye

Principal investigatorBRAIN2022ALS Canada - Brain Canada Discovery Grants

Principal investigators: Yucel, Yeni

Keywords: Neurodegeneration; ALS

$125,000

Tracking Nanoparticles with Whole-Animal Imaging and Hyperspectral Microscopy: A Novel Strategy for Identifying Biomarkers and Treating Diabetes

Principal investigatorONTARIO2013Ontario Research Fund - Research Infrastructure: Small Infrastructure Fund - Round 026 - 2012 - October

Principal investigators: Yucel, Yeni

$397,548

Validation of non-invasive rapid eye movements measurement as screening tool for mild traumatic brain injury

Co-investigatorCIHR2012Operating Grant

Principal investigators: Cusimano, Michael D

Keywords: Injury Control; Injury Prevention; Magnetic Resonance Imaging And Spectroscopy; Mild Traumatic Brain Injury; Neuropsychological Testing; Neurosurgery; Ophthalmology; Post-Concussion Syndrome; Quality Of Life; Saccadometry

$250,140

Tracking Nanoparticles with Whole-Animal Imaging and Hyperspectral Microscopy: A Novel Strategy for Identifying Biomarkers and Treating Diabetes.

Principal investigatorCFI2012John R. Evans Leaders Fund: John R. Evans Leaders Fund – Funding for research infrastructure

Principal investigators: Yucel, Yeni

Keywords: hyperspectral microscopy, in vivo imaging, near infrared angiography, diabetes complications, kidney, eye, brain, coagulation, neuroscience, nanotechnology, pathology

$397,628

Lymphatics as a novel target to treat glaucoma

Nominated PICIHR2011Operating Grant

Principal investigators: Yucel, Yeni H

Keywords: Aqueous Humour Outflow; Eye Physiology; Glaucoma; Lymphatic Circulation; Molecular And Cellular Imaging; Molecular Biology

$579,963

From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.

Frequent collaborators

Department of Laboratory Medicine & Pathobiology
Department of Ophthalmology & Vision Sciences
Department of Anesthesiology and Pain Medicine
Clinical Public Health Division
Department of Medical Biophysics
Interdepartmental Division of Critical Care
Department of Medicine
Other

1 shared papers, latest 2025

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Paper to mentionMention their BRAIN grant from 2022

Subject: Prospective PhD student Dear Professor Yücel, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Intraocular Pressure and Retinal Nerve Fiber Layer Changes in a Microgravity Mouse Model and Relevance to Spaceflight-Associated Neuro-Ocular Syndrome." (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your BRAIN-funded project "Imaging a New ALS Biomarker in the Eye" (2022), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]