Ali Khan, Western University

Research

Read how they describe their research on their Western University profile.

Mri Aging Brain Diffusion Mri Lifespan Light Sheet Microscopy Microstructure

Latest papers

Putative glymphatic function and free water in schizophrenia: A 7T DTI study across psychosis stages.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
Conceptual disorganization and redistribution of resting-state cortical hubs in untreated first-episode psychosis: A 7T study.
NPJ schizophrenia · 2021
Convergence of cortical types and functional motifs in the human mesiotemporal lobe.
eLife · 2020

All 5 publications

Latest funding

Microstructural brain aging across the lifespan of mice
CIHR · 2025 · Principal investigator
$998,326
The use of semaglutide and resistance exercise to combat cognitive decline in older adults with Type 2 Diabetes: A combined pharmacological and lifestyle intervention
CIHR · 2024 · Co-investigator
$929,475
Canada Research Chair - Tier 2
CIHR · 2023 · Nominated PI
$500,000

All 15 grants and awards

5 publications.

01

Putative glymphatic function and free water in schizophrenia: A 7T DTI study across psychosis stages.

Qi G, Zhang Y, Wang YL, Anjum F, Theberge J, Jiang Y, Khan A, Palaniyappan L

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2026

DOI: 10.1038/s41386-026-02391-5 PMID: 41876826

02

Conceptual disorganization and redistribution of resting-state cortical hubs in untreated first-episode psychosis: A 7T study.

Dey A, Dempster K, MacKinley M, Jeon P, Das T, Khan A, Gati J, Palaniyappan L

NPJ schizophrenia2021

DOI: 10.1038/s41537-020-00130-3 PMID: 33500416

03

Convergence of cortical types and functional motifs in the human mesiotemporal lobe.

Paquola C, Benkarim O, DeKraker J, Larivière S, Frässle S, Royer J, Tavakol S, Valk S, Bernasconi A, Bernasconi N, Khan A, Evans AC, Razi A, Smallwood J, Bernhardt BC

eLife2020

DOI: 10.7554/elife.60673 PMID: 33146610

04

IJCARS: MICCAI 2019 special issue.

Peters T, Essert C, Khan A

International journal of computer assisted radiology and surgery2020Senior author

DOI: 10.1007/s11548-020-02279-9 PMID: 33085035

05

The DTI Challenge: Toward Standardized Evaluation of Diffusion Tensor Imaging Tractography for Neurosurgery.

Pujol S, Wells W, Pierpaoli C, Brun C, Gee J, Cheng G, Vemuri B, Commowick O, Prima S, Stamm A, Goubran M, Khan A, Peters T, Neher P, Maier-Hein KH, Shi Y, Tristan-Vega A, Veni G, Whitaker R, Styner M, Westin CF, Gouttard S, Norton I, Chauvin L, Mamata H, Gerig G, Nabavi A, Golby A, Kikinis R

Journal of neuroimaging : official journal of the American Society of Neuroimaging2015

DOI: 10.1111/jon.12283 PMID: 26259925

Microstructural brain aging across the lifespan of mice

Principal investigatorCIHR2025Project Grant

Principal investigators: Baron, Corey A; Khan, Ali R

Keywords: Aging; Brain; Diffusion Mri; Lifespan; Light Sheet; Microscopy; Microstructure; Mouse; Mri; Neurodegeneration

$998,326

The use of semaglutide and resistance exercise to combat cognitive decline in older adults with Type 2 Diabetes: A combined pharmacological and lifestyle intervention

Co-investigatorCIHR2024Project Grant

Principal investigators: Nagamatsu, Lindsay S; Reichert, Sonja M

Keywords: Rct; Resistance Exercise; Semaglutide; Type 2 Diabetes

$929,475

Canada Research Chair - Tier 2

Nominated PICIHR2023Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Khan, Ali R

Keywords: Crc

$500,000

TRIDENT: TRanslational Initiative to DE-risk NeuroTherapeutics

Co-investigatorSSHRC2022New Frontiers in Research Fund - Transformation

Principal investigators: Menon, Ravi

Keywords: cognition; drug discovery; mouse models; marmoset; organoids; imaging; open science; neurodegenerative disease; neurochemistry; neural circuits; sex differences

$8,000,000

Schizophrenia and Cortical Association Fibres: A connectomic study

SupervisorCIHR2021Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Van Dyken, Peter

Keywords: Diffusion Weighted Imaging; Fmri; Graph Theory; Mri; Schizophrenia; Tractography

$105,000

Microstructural MRI in Temporal Lobe Epilepsy

Co-investigatorCIHR2021Project Grant

Principal investigators: Baron, Corey A

Keywords: Axon; Diffusion; Hippocampus; Histology; Microscopic Anisotropy; Microstructure; Mri; Non-Cartesian; Subfield; Temporal Lobe Epilepsy

$581,400

Origins of memory systems in the fetal and neonatal brain

Co-investigatorSSHRC2021New Frontiers in Research Fund - Exploration

Principal investigators: Duerden, Emma

Keywords: Memory development Hippocampus MRI fetus newborn brain music maternal voice prenatal health

$250,000

Advancing Clinically-Useful Diagnostic and Progression Markers of PD with Neuroimaging

Principal investigatorCIHR2019Project Grant

Principal investigators: MacDonald, Penny A; Khan, Ali R

Keywords: Biomarker; Cognition; Dopamine; Machine Learning; Neuroimaging; Parkinson'S Disease; Structural Imaging

$493,426

Probing hippocampal integrity with ultra-high resolution MRI and behaviour in temporal lobe epilepsy

Nominated PICIHR2016Project Grant

Principal investigators: Khan, Ali R; Kohler, Stefan

Keywords: Circuit; Epilepsy; Functional Connectivity; Hippocampal Sclerosis; Hippocampus; Magnetic Resonance Imaging; Memory; Mri; Resting State Fmri; Subfield

$458,700

Origins, Consequences and Outcomes of Neuroprogression in First Episode Schizophrenia

Co-investigatorCIHR2016Foundation Grant

Principal investigators: Palaniyappan, Lena K

Keywords: Connectivity; Magnetic Resonance Spectroscopy; Neuroimaging; Oxidative Stress; Positron Emission Tomography; Psychosis; Schizophrenia; Ultra-High Field Mri

$964,309

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Department of Medical Biophysics
Department of Psychiatry
Psychiatry
Other

Co-authors at Western University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Lena Palaniyappan

Department of Psychiatry

2 shared papers, latest 2026

Terry Peters

Department of Medical Biophysics

2 shared papers, latest 2020

Lena Palaniyappan

Psychiatry

1 shared papers, latest 2026

Kara Dempster

Faculty

1 shared papers, latest 2021

Jean Theberge

Department of Medical Biophysics

1 shared papers, latest 2026

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Mri Dear Professor Khan, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Putative glymphatic function and free water in schizophrenia: A 7T DTI study across psychosis stages." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Microstructural brain aging across the lifespan of mice" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]