Faculty profile
Stephen Pasternak
Back to facultyResearch
Read how they describe their research on their Western University profile.
Latest papers
Regional free-water diffusion is more strongly related to neuroinflammation than neurodegeneration
Journal of Neurology · 2025
Blarcamesine for the treatment of Early Alzheimer's Disease: Results from the ANAVEX2-73-AD-004 Phase IIB/III trial.
The journal of prevention of Alzheimer's disease · 2025
White matter hyperintensities and smaller cortical thickness are associated with neuropsychiatric symptoms in neurodegenerative and cerebrovascular diseases
Alzheimer's Research and Therapy · 2023
Latest funding
- $1,227,826
Using circulating microglia extracellular vesicles to discriminate microglia activation phenotype, and cognitive outcomes in comorbid AD and stroke
CIHR · 2026 · Co-investigator
- $1,067,175
Precision therapeutics for genetic disorders with transfer ribonucleic acids
CIHR · 2024 · Co-investigator
- $1,075,000
Developing Novel Brain Imaging and Blood Testing Against a Major Early Disease Driver for Timely Diagnosis and Effective Treatment of Age-Dependent Tauopathies
CIHR · 2024 · Principal investigator
11 publications.
Regional free-water diffusion is more strongly related to neuroinflammation than neurodegeneration
Sumra V, Hadian M, Dilliott AA, Farhan SMK, Frank AR, Lang AE, Roberts AC, Troyer A, Arnott SR, Marras C
Blarcamesine for the treatment of Early Alzheimer's Disease: Results from the ANAVEX2-73-AD-004 Phase IIB/III trial.
Macfarlane S, Grimmer T, Teo K, O'Brien TJ, Woodward M, Grunfeld J, Mander A, Brodtmann A, Brew BJ, Morris P, Short C, Kurrle S, Lai R, Bharadwaj S, Drysdale P, Sturm J, Lewis SJG, Barton D, Kalafatis C, Sharif S, Perry R, Mannering N, MacSweeney JE, Pearson S, Evans C, Krishna V, Thompson A, Munisamy M, Bhatt N, Asher A, Connell S, Lynch J, Rutgers SM, Dautzenberg PL, Prins N, Oschmann P, Frölich L, Tacik P, Peters O, Wiltfang J, Henri-Bhargava A, Smith E, Pasternak S, Frank A, Chertkow H, Ingram J, Hsiung GR, Brittain R, Tartaglia C, Cohen S, Villa LM, Gordon E, Jubault T, Guizard N, Tucker A, Kaufmann WE, Jin K, Chezem WR, Missling CU, Sabbagh MN
White matter hyperintensities and smaller cortical thickness are associated with neuropsychiatric symptoms in neurodegenerative and cerebrovascular diseases
Ozzoude M, Varriano B, Beaton D, Ramirez J, Adamo S, Holmes MF, Scott CJM, Gao F, Sunderland KM, McLaughlin P
Neuropsychiatric Symptom Burden across Neurodegenerative Disorders and its Association with Function
Kapustin D, Zarei S, Wang W, Binns MA, McLaughlin PM, Abrahao A, Black SE, Borrie M, Breen D, Casaubon L
Rare neurovascular genetic and imaging markers across neurodegenerative diseases
Dilliott AA, Berberian SA, Sunderland KM, Binns MA, Zimmer J, Ozzoude M, Scott CJM, Gao F, Lang AE, Breen DP
Investigating the contribution of white matter hyperintensities and cortical thickness to empathy in neurodegenerative and cerebrovascular diseases
Ozzoude M, Varriano B, Beaton D, Ramirez J, Holmes MF, Scott CJM, Gao F, Sunderland KM, McLaughlin P, Rabin J
Association of apolipoprotein E variation with cognitive impairment across multiple neurodegenerative diagnoses
Dilliott AA, Sunderland KM, McLaughlin PM, Roberts AC, Evans EC, Abrahao A, Binns MA, Black SE, Borrie M, Casaubon LK
Comparison of Behavior-Related Features in the MMSE Sentence in Behavioral Variant Frontotemporal Dementia and Alzheimer's Disease.
Ruiz-Garcia R, Yu S, Richardson L, Roberts A, Pasternak S, Stewart C, Finger E
Financial capacity in frontotemporal dementia and related presentations.
Gill S, Blair M, Kershaw M, Jesso S, MacKinley J, Coleman K, Pantazopoulos K, Pasternak S, Finger E
Oxytocin for frontotemporal dementia: a randomized dose-finding study of safety and tolerability.
Finger EC, MacKinley J, Blair M, Oliver LD, Jesso S, Tartaglia MC, Borrie M, Wells J, Dziobek I, Pasternak S, Mitchell DG, Rankin K, Kertesz A, Boxer A
Using circulating microglia extracellular vesicles to discriminate microglia activation phenotype, and cognitive outcomes in comorbid AD and stroke
Principal investigators: Whitehead, Shawn N; Badhwar, Amanpreet; Edwards, Jodi D
Keywords: Alzheimer'S Disease; Biomarkers; Dementia; Microglia; Stroke
Precision therapeutics for genetic disorders with transfer ribonucleic acids
Principal investigators: O'Donoghue, Patrick
Keywords: Amyotrophic Lateral Sclerosis; Duchenne'S Muscular Dystrophy; Huntington'S Disease; Missense Suppression; Polyq; Premature Stop Codon; Protein Aggregation; Transfer Rna
Developing Novel Brain Imaging and Blood Testing Against a Major Early Disease Driver for Timely Diagnosis and Effective Treatment of Age-Dependent Tauopathies
Principal investigators: Lu, Kun Ping; Bartha, Robert; Lee, Ting-Yim; Paré, Guillaume; Pasternak, Stephen H; Zhou, Xiao Zhen
Keywords: Alzheimer'S Disease; Blood Biomarker; Dementia; Diagnostics; Pet Imaging; Phosphorylated Tau; Pin1; Protein Conformation; Tauopathies; Traumatic Brain Injury
Non Invasive and early detection of Alzheimer's Disease biomarkers using extracellular vesicles
Principal investigators: MEDAPATI, MANOJ REDDY
Keywords: Ad Inflammatory Ev Biomarkers; Biomarkers Of Ad; Biomarkers Of Cognitive Decline; Extracellular Vesicles (Evs) Biomarkers; Nanoflow Detection Of Evs; Staging Of Ad Using Ev Profile; Unbiased Ev Proteomics
Investigating the role of lysosomal exocytosis in Alzheimer's disease
Principal investigators: Tsang, Adrianna R
Keywords: Aggregation; Alzheimer'S Disease; Beta-Amyloid; Lysosome; Secretion; Tau
Understanding lysosomal secretion in neurons: a novel mechanism responsible for beta-amyloid release.
Principal investigators: Pasternak, Stephen H
Keywords: Alzheimer'S Disease; Beta-Amyloid; Cell Biology; Exocytosis; Live Cell Imaging; Lysosome
Characterizing the Role of the Endosomal/ Lysosomal system in beta-Amyloid Production and Secretion in Alzheimer's disease
Principal investigators: Pasternak, Stephen H
Keywords: Alzheimer'S Disease; Cell Biology; Confocal Microscopy; Endocytosis; Fluorescent Protein Tags; Live Cell Imaging; Macropinocytosis; Total Intermal Reflection Microscopy
Magnetic Resonance PARACEST Imaging of In-vivo Protease Activity
Principal investigators: Bartha, Robert
Keywords: Alzheimer Disease; Chemical Exchange; Contrast Agents; Magnetic Resonance Imaging; Paracest; Protease
Following the trafficking and cleavage of the Amyloid Precursor Protein (APP) using Photoactivatable green fluorescent protein.
Principal investigators: Tam, Joshua
Keywords: Alzheimer'S Disease; Amyloid Precursor Protein; Protein Trafficking; Proteolytic Cleavage
Characterizing the role of the endosomal/ lysosomal system in Alzheimer's Disease
Principal investigators: Pasternak, Stephen H
Keywords: Alzheimer'S Disease; Cell Biology; Confocal Microscopy; Endocytosis; Fluorescent Protein Tags; Free Flow Electrophoresis; Total Internal Reflection Microscopy
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Elizabeth Finger and Mario Masellis: 124 shared papers
- Demetrios Sahlas and Dar Dowlatshahi: 38 shared papers
- Robert Bartha and Manuel Montero Odasso: 36 shared papers
- Robert Bartha and Mario Masellis: 28 shared papers
- Mario Masellis and Ekaterina Rogaeva: 28 shared papers
- Connie Marras and Mario Masellis: 27 shared papers
- Dar Dowlatshahi and Gustavo Saposnik: 27 shared papers
- Demetrios Sahlas and Mario Masellis: 24 shared papers
- Mario Masellis and Sanjeev Kumar: 24 shared papers
- Demetrios Sahlas and Gustavo Saposnik: 23 shared papers
- John Turnbull and Demetrios Sahlas: 20 shared papers
- Mario Masellis and Andrew Frank: 19 shared papers
- Mario Masellis and Dar Dowlatshahi: 19 shared papers
- Mario Masellis and Gustavo Saposnik: 19 shared papers
- Connie Marras and David Grimes: 18 shared papers
- Mario Masellis and Maged Goubran: 18 shared papers
- Mario Masellis and David Grimes: 18 shared papers
- Andrew Frank and Sanjeev Kumar: 18 shared papers
- Robert Bartha and Dar Dowlatshahi: 17 shared papers
- Michael Borrie and Sanjeev Kumar: 17 shared papers
- Demetrios Sahlas and Michael Borrie: 16 shared papers
- Michael Borrie and Mario Masellis: 16 shared papers
- Mario Masellis and Manuel Montero Odasso: 16 shared papers
- John Turnbull and Mario Masellis: 15 shared papers
- Elizabeth Finger and Robert Bartha: 15 shared papers
- Elizabeth Finger and Michael Borrie: 15 shared papers
- Elizabeth Finger and Ekaterina Rogaeva: 15 shared papers
- Elizabeth Finger and Andrew Frank: 15 shared papers
- Connie Marras and Anthony Lang: 15 shared papers
- John Turnbull and Dar Dowlatshahi: 13 shared papers
- Mario Masellis and Dallas Seitz: 13 shared papers
- Dallas Seitz and Sanjeev Kumar: 13 shared papers
- John Turnbull and Marvin Chum: 12 shared papers
- David Grimes and Sanjeev Kumar: 12 shared papers
- Connie Marras and Ekaterina Rogaeva: 11 shared papers
- Robert Bartha and Maged Goubran: 11 shared papers
- Dallas Seitz and Andrew Frank: 11 shared papers
- Michael Borrie and Manuel Montero Odasso: 10 shared papers
- Demetrios Sahlas and Maged Goubran: 9 shared papers
- Demetrios Sahlas and Marvin Chum: 8 shared papers
- Elizabeth Finger and Stephen Pasternak: 8 shared papers
- Mario Masellis and Anthony Lang: 8 shared papers
- Michael Borrie and Stephen Pasternak: 7 shared papers
- Manuel Montero Odasso and Howard Chertkow: 7 shared papers
- Demetrios Sahlas and Brian Levine: 6 shared papers
- Demetrios Sahlas and Stephen Pasternak: 6 shared papers
- Marvin Chum and Mario Masellis: 6 shared papers
- Connie Marras and Brian Levine: 6 shared papers
- Connie Marras and Stephen Pasternak: 6 shared papers
- Brian Levine and Mario Masellis: 6 shared papers
- Michael Borrie and Howard Chertkow: 6 shared papers
- Mario Masellis and Stephen Pasternak: 6 shared papers
- Mario Masellis and Angela Roberts: 6 shared papers
- Stephen Pasternak and Andrew Frank: 6 shared papers
- Stephen Pasternak and Dar Dowlatshahi: 6 shared papers
- Stephen Pasternak and David Grimes: 6 shared papers
- Stephen Pasternak and Sanjeev Kumar: 6 shared papers
- Stephen Pasternak and Gustavo Saposnik: 6 shared papers
- Anthony Lang and Ekaterina Rogaeva: 6 shared papers
- John Turnbull and Stephen Pasternak: 5 shared papers
- Connie Marras and Angela Roberts: 5 shared papers
- Howard Chertkow and Sanjeev Kumar: 5 shared papers
- Angela Roberts and David Grimes: 5 shared papers
- Robert Bartha and Stephen Pasternak: 4 shared papers
- Stephen Pasternak and Dallas Seitz: 4 shared papers
- Stephen Pasternak and Angela Roberts: 4 shared papers
- Stephen Pasternak and Ekaterina Rogaeva: 3 shared papers
- John Turnbull and Jennifer Rabin: 2 shared papers
- Demetrios Sahlas and Jennifer Rabin: 2 shared papers
- Marvin Chum and Stephen Pasternak: 2 shared papers
- Marvin Chum and Jennifer Rabin: 2 shared papers
- Eric Smith and Mario Masellis: 2 shared papers
- Eric Smith and Manuel Montero Odasso: 2 shared papers
- Eric Smith and Howard Chertkow: 2 shared papers
- Stephen Pasternak and Manuel Montero Odasso: 2 shared papers
- Stephen Pasternak and Jennifer Rabin: 2 shared papers
- Stephen Pasternak and Maged Goubran: 2 shared papers
- Eric Smith and Stephen Pasternak: 1 shared paper
- Brian Levine and Stephen Pasternak: 1 shared paper
- Michael Borrie and Adam Boxer: 1 shared paper
- Stephen Pasternak and Adam Boxer: 1 shared paper
- Stephen Pasternak and Howard Chertkow: 1 shared paper
- Stephen Pasternak and Anthony Lang: 1 shared paper
- Adam Boxer and Ekaterina Rogaeva: 1 shared paper
- Medicine
- Department of Medicine
- Clinical Neurological Sciences
- John P. Robarts Research Institute
- Medicine/Neurology
- Department of Psychiatry
- School of Communication Sciences & Disorders
- Other
Co-authors at Western University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Elizabeth Finger
Clinical Neurological Sciences
8 shared papers, latest 2025
Michael Borrie
John P. Robarts Research Institute
7 shared papers, latest 2025
Gustavo Saposnik
Department of Medicine
6 shared papers, latest 2025
Andrew Frank
Faculty
6 shared papers, latest 2025
Dar Dowlatshahi
Department of Medicine
6 shared papers, latest 2025
David Grimes
Department of Medicine
6 shared papers, latest 2025
Sanjeev Kumar
Department of Psychiatry
6 shared papers, latest 2025
Demetrios Sahlas
Medicine
6 shared papers, latest 2025
Mario Masellis
Medicine
6 shared papers, latest 2025
Connie Marras
Medicine/Neurology
6 shared papers, latest 2025
John Turnbull
Medicine
5 shared papers, latest 2023
Angela Roberts
School of Communication Sciences & Disorders
4 shared papers, latest 2023
Dallas Seitz
Medicine
4 shared papers, latest 2023
Robert Bartha
Biochemistry
4 shared papers, latest 2025
Ekaterina Rogaeva
Tanz Centre for Research in Neurodegenerative Diseases
3 shared papers, latest 2025
Maged Goubran
Department of Medical Biophysics
2 shared papers, latest 2023
Manuel Montero Odasso
Department of Epidemiology and Biostatistics
2 shared papers, latest 2023
Jennifer Rabin
Faculty
2 shared papers, latest 2023
Marvin Chum
Medicine
2 shared papers, latest 2023
Malcolm Binns
Biostatistics Division
1 shared papers, latest 2025
Michael Borrie
Medicine
1 shared papers, latest 2015
Howard Chertkow
Medicine
1 shared papers, latest 2025
Anthony Lang
Faculty
1 shared papers, latest 2023
Wei Wang
Faculty
1 shared papers, latest 2023
Howard Chertkow
Psychology
1 shared papers, latest 2025
Adam Boxer
Faculty
1 shared papers, latest 2015
Brian Levine
Rotman Research Institute
1 shared papers, latest 2023
Eric Smith
Clinical Neurosciences
1 shared papers, latest 2025
Tarek Rajji
Faculty
1 shared papers, latest 2025
A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.
Profile data last refreshed on November 9, 2025 from the university directory, publication records and CIHR, NSERC and SSHRC funding.