Faculty profile
Aravindhan Ganesan
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Read how they describe their research on their Wilfrid Laurier University profile.
Latest papers
Membrane-coupled conformational switching of VISTA regulates immune checkpoint signaling via CC′ loop accessibility
bioRxiv (Cold Spring Harbor Laboratory) · 2026 · first author
Neuropharmacology of Nicotine Addiction and Therapeutic Strategies for Smoking Cessation.
Biology · 2026 · senior author
Revealing the impact of active site residues in modeling the inhibition mechanism of SARS-Cov-2 main protease by GC373.
Computers in biology and medicine · 2025 · senior author
Latest funding
- $152,000
IntegCore: An Integrated Computational and Experimental Platform for Advanced Biomolecular Research and Discovery
CFI · 2026 · Principal investigator
- $148,000
Development of computational models to understand the dynamic molecular recognition mechanisms of cannabinoid receptors
NSERC · 2021 · Principal investigator
- $12,500
Development of computational models to understand the dynamic molecular recognition mechanisms of cannabinoid receptors
NSERC · 2021 · Principal investigator
59 publications.
Membrane-coupled conformational switching of VISTA regulates immune checkpoint signaling via CC′ loop accessibility
Aravindhan Ganesan, Varun Reddy, Norman Ly
Neuropharmacology of Nicotine Addiction and Therapeutic Strategies for Smoking Cessation.
Hefny AA, Karuturi RC, Kalyaanamoorthy S, Rao PPN, Ganesan A
Revealing the impact of active site residues in modeling the inhibition mechanism of SARS-Cov-2 main protease by GC373.
Aboelnga MM, Petgrave M, Kalyaanamoorthy S, Ganesan A
Computational Mapping of Conformational Dynamics and Interaction Hotspots of Human VISTA with pH-Selective Antibodies.
Ly N, Ramgoolam SD, Ganesan A
Investigating the Interactions of a Cyclic Peptide Hormone Somatostatin and Its Derivatives on Amyloid-Beta Aggregation.
Pham AT, Zhao Y, Oo A, Hefny AA, Ganesan A, Rao PPN
Post-Translational Modifications in Tau and Their Roles in Alzheimer's Pathology.
Kalyaanamoorthy S, Opare SK, Xu X, Ganesan A, Rao PPN
Deciphering the Molecular Association of Human CRIP1a with an Agonist-Bound Cannabinoid Receptor 1.
Petgrave M, Ramgoolam SD, Ganesan A
Design and Development of COX-II Inhibitors: Current Scenario and Future Perspective.
Chahal S, Rani P, Kiran, Sindhu J, Joshi G, Ganesan A, Kalyaanamoorthy S, Mayank, Kumar P, Singh R, Negi A
The H163A mutation unravels an oxidized conformation of the SARS-CoV-2 main protease.
Tran N, Dasari S, Barwell SAE, McLeod MJ, Kalyaanamoorthy S, Holyoak T, Ganesan A
Sequence- and structure-specific RNA oligonucleotide binding attenuates heterogeneous nuclear ribonucleoprotein A1 dysfunction.
Clarke JP, Thibault PA, Fatima S, Salapa HE, Kalyaanamoorthy S, Ganesan A, Levin MC
IntegCore: An Integrated Computational and Experimental Platform for Advanced Biomolecular Research and Discovery
Principal investigators: Ganesan, Aravindhan
Keywords: High Performance Computing, Artificial Intelligence, Molecular Modeling and Simulation, Drug Discovery, Surface Plasmon Resonance, Binding Assay, Bio-innovation High-performance computer, Secured data storage, Surface Plasmon Resonance
Development of computational models to understand the dynamic molecular recognition mechanisms of cannabinoid receptors
Principal investigators: Ganesan, Aravindhan
Keywords: computational modelling; cannabinoid receptors; small molecules; molecular dynamics; machine learning models; virtual screening; molecular mechanisms; gpcrs; competitive binding assays; receptor activation
Development of computational models to understand the dynamic molecular recognition mechanisms of cannabinoid receptors
Principal investigators: Ganesan, Aravindhan
An innovative approach designed to disrupt RNA binding protein aggregation and attenuate neurodegeneration in multiple sclerosis
Principal investigators: Levin, Michael
Keywords: multiple sclerosis neurodegeneration optogenetics bioinformatics computational modeling molecular dynamics peptide:protein dynamics hnRNP A1 RNA binding protein proteinopathy
From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.
Frequent collaborators
- Tahir Choulli and T Choulli: 85 shared papers
- Subha Kalyaanamoorthy and Aravindhan Ganesan: 19 shared papers
- Michael Houghton and Khaled Barakat: 18 shared papers
- Khaled Barakat and Aravindhan Ganesan: 18 shared papers
- Khaled Barakat and Arno Siraki: 10 shared papers
- Khaled Barakat and Subha Kalyaanamoorthy: 10 shared papers
- Frederick West and Khaled Barakat: 9 shared papers
- Shokrollah Elahi and Khaled Barakat: 8 shared papers
- Shokrollah Elahi and Arno Siraki: 8 shared papers
- Shokrollah Elahi and Michael Houghton: 4 shared papers
- Frederick West and Arno Siraki: 4 shared papers
- Aravindhan Ganesan and Praveen Rao: 4 shared papers
- Shokrollah Elahi and Frederick West: 3 shared papers
- Subha Kalyaanamoorthy and Praveen Rao: 3 shared papers
- Shokrollah Elahi and Aravindhan Ganesan: 2 shared papers
- Michael Houghton and Subha Kalyaanamoorthy: 2 shared papers
- Michael Houghton and Aravindhan Ganesan: 2 shared papers
- Todd Holyoak and Subha Kalyaanamoorthy: 2 shared papers
- Todd Holyoak and Aravindhan Ganesan: 2 shared papers
- Subha Kalyaanamoorthy and Michael Levin: 2 shared papers
- Aravindhan Ganesan and Michael Levin: 2 shared papers
- Frederick West and Aravindhan Ganesan: 1 shared paper
- Khaled Barakat and Tahir Choulli: 1 shared paper
- Khaled Barakat and Michael Levin: 1 shared paper
- Khaled Barakat and Sedami Gnidehou: 1 shared paper
- Khaled Barakat and T Choulli: 1 shared paper
- Arno Siraki and Aravindhan Ganesan: 1 shared paper
- Tahir Choulli and Aravindhan Ganesan: 1 shared paper
- Aravindhan Ganesan and Sedami Gnidehou: 1 shared paper
- Aravindhan Ganesan and T Choulli: 1 shared paper
- Science
- Department of Chemistry
- School of Pharmacy
- Medical Microbiology and Immunology Dept
- Department of Medicine
- Mike Petryk School of Dentistry
- Department of Biology
- Other
Co-authors at Wilfrid Laurier University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Subha Kalyaanamoorthy
Department of Chemistry
19 shared papers, latest 2026
Khaled Barakat
Faculty
18 shared papers, latest 2022
Praveen Rao
School of Pharmacy
4 shared papers, latest 2026
Michael Levin
Department of Medicine
2 shared papers, latest 2023
Shokrollah Elahi
Mike Petryk School of Dentistry
2 shared papers, latest 2020
Michael Houghton
Medical Microbiology and Immunology Dept
2 shared papers, latest 2019
Todd Holyoak
Department of Biology
2 shared papers, latest 2023
Sedami Gnidehou
Campus Saint-Jean - Académique
1 shared papers, latest 2019
T Choulli
Mathematics & Statistical Sciences
1 shared papers, latest 2018
Tahir Choulli
Mathematical and Statistical Sciences
1 shared papers, latest 2018
Frederick West
Chemistry
1 shared papers, latest 2019
Arno Siraki
Faculty
1 shared papers, latest 2019
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Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.