This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a York University directory, so their courses may be missing. Find their university profile.
Latest papers
Mild and Selective Oxidation of 4-Alkylpyridines to 4-Acylpyridines under an Oxygen Atmosphere.
The Journal of organic chemistry · 2026 · senior author
Mild and catalytic electrocyclizations of heptatrienyl anions.
Chemical science · 2024 · senior author
Stability and reactivity of alkylidene dihydropyridines.
Organic & biomolecular chemistry · 2024 · senior author
Latest funding
- $43,000
Modern Approaches to Electrocyclization of Heptatrienyl Anions
NSERC · 2024 · Principal investigator
- $879,750
Development of novel ß-catenin inhibitors as potential therapeutics for ovarian cancer
CIHR · 2019 · Co-investigator
- $253,848
Cross-Coupling Reactions Leading to Chiral Heterocyclic Scaffolds for Drug Development and Manufacturing
NSERC · 2018 · Principal investigator
24 publications.
Mild and Selective Oxidation of 4-Alkylpyridines to 4-Acylpyridines under an Oxygen Atmosphere.
Doan B, Puzhitsky M, Pradhan E, Rasheed F, Nikolaev A, Zeng T, Orellana A
Mild and catalytic electrocyclizations of heptatrienyl anions.
Rasheed F, Nikolaev A, Dhesi A, Zeng T, Guo YX, Krishna Y, Komijani S, Orellana A
Stability and reactivity of alkylidene dihydropyridines.
Puzhistky M, Pradhan E, Nikolaev A, Zeng T, Fishlock D, Orellana A
Soft Fluorination of 4-Alkylpyridines.
Rasheed F, Shi J, Zeng T, Krishna Y, Fishlock D, Orellana A
Mild Installation of Piperidines on 4-Alkylpyridines.
Shi J, Rasheed F, Fishlock D, Orellana A
The omega-3 hydroxy fatty acid 7(S)-HDHA is a high-affinity PPARα ligand that regulates brain neuronal morphology.
Liu J, Sahin C, Ahmad S, Magomedova L, Zhang M, Jia Z, Metherel AH, Orellana A, Poda G, Bazinet RP, Attisano L, Cummins CL, Peng H, Krause HM
Alkylidene Dihydropyridines Are Surrogates for Pyridylic Anions in the Conjugate Addition to α,β-Unsaturated Ketones.
Shi J, Sayyad A, Fishlock D, Orellana A
Pyridylic anions are soft nucleophiles in the palladium-catalyzed C(sp3)-H allylation of 4-alkylpyridines.
Wasfy N, Rasheed F, Robidas R, Hunter I, Shi J, Doan B, Legault CY, Fishlock D, Orellana A
Enantioselective Synthesis of 7(S)-Hydroxydocosahexaenoic Acid, a Possible Endogenous Ligand for PPARα.
Zhang M, Sayyad AA, Dhesi A, Orellana A
The Acid-Free Cyclopropanol-Minisci Reaction Reveals the Catalytic Role of Silver-Pyridine Complexes.
Nikolaev A, Legault CY, Zhang M, Orellana A
Modern Approaches to Electrocyclization of Heptatrienyl Anions
Principal investigators: Orellana, Arturo
Keywords: pericyclic chemistry; organometallic chemistry; total synthesis; catalysis; electrocyclization; cycloheptanes
Development of novel ß-catenin inhibitors as potential therapeutics for ovarian cancer
Principal investigators: Peng, Chun
Keywords: Ovarian Cancer; Small Molecule Inhibitors; Wnt/Beta-Catenin Signaling
Cross-Coupling Reactions Leading to Chiral Heterocyclic Scaffolds for Drug Development and Manufacturing
Principal investigators: Orellana, Arturo
Developing small molecules targeting LXRb for the treatment of glucocorticoid induced diabetes
Principal investigators: Orellana, Arturo; Cummins, Carolyn L
Keywords: Drug Discovery; Glucocorticoids; Lxrb; Medicinal Chemistry; Nuclear Receptors; Pharmacokinetics
Exploiting Neglected Reactivity to Develop New Tools for Organic Synthesis and Medicinal Chemistry
Principal investigators: Orellana, Arturo
Defining the structural basis for LXR beta antagonism
Principal investigators: Cummins, Carolyn L
Keywords: Co-Transfection Assays; Dexamethasone; Ligand Binding Assays; Liver X Receptor; Nuclear Receptor; P450 Metabolism; Physicochemical Properties; Primary Hepatocytes; Structure Based Drug Design; Synthetic Chemistry
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Andrew Advani and Arturo Orellana: 1 shared paper
- Liliana Attisano and Zhengping Jia: 1 shared paper
- Liliana Attisano and Arturo Orellana: 1 shared paper
- Liliana Attisano and Hui Peng: 1 shared paper
- Zhengping Jia and Arturo Orellana: 1 shared paper
- Zhengping Jia and Hui Peng: 1 shared paper
- Arturo Orellana and Hui Peng: 1 shared paper
- Medicine
- Department of Biochemistry
- Other
Co-authors at York University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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