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Latest papers
Severe hypophosphataemia and hypocalcaemia following intravenous ferric derisomaltose and denosumab administration.
BMJ case reports · 2024 · senior author
DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide.
International journal of biological sciences · 2018
Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment.
Scientific reports · 2016
Latest funding
- $761,176
X-linked Hypophosphatemic Rickets (XLH), a Primary Skeletal Dysplasia with Superimposed Rickets
CIHR · 2023 · Nominated PI
- $430,314
Targeting Vitamin D Metabolism in Osteoarthritis
CIHR · 2020 · Nominated PI
- $895,050
CYP24A1 Enzymatic Activity in FGF23-Mediated Renal Phosphate Wasting Disorders
CIHR · 2017 · Nominated PI
8 publications.
Severe hypophosphataemia and hypocalcaemia following intravenous ferric derisomaltose and denosumab administration.
Kritzinger J, Wyse J, Karaplis A
DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide.
Zhang Y, Chen G, Gu Z, Sun H, Karaplis A, Goltzman D, Miao D
Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment.
Zhou X, Dai X, Wu X, Ji J, Karaplis A, Goltzman D, Yang X, Miao D
PTHrP Nuclear Localization and Carboxyl Terminus Sequences Modulate Dental and Mandibular Development in Part via the Action of p27.
Sun W, Wu J, Huang L, Liu H, Wang R, Karaplis A, Goltzman D, Miao D
Deficiency of the parathyroid hormone-related peptide nuclear localization and carboxyl terminal sequences leads to premature skin ageing partially mediated by the upregulation of p27.
Jiang M, Chen G, Lu N, Zhang Y, Jin S, Karaplis A, Goltzman D, Miao D
The p27 Pathway Modulates the Regulation of Skeletal Growth and Osteoblastic Bone Formation by Parathyroid Hormone-Related Peptide.
Zhu M, Zhang J, Dong Z, Zhang Y, Wang R, Karaplis A, Goltzman D, Miao D
Deletion of the nuclear localization sequences and C-terminus of PTHrP impairs embryonic mammary development but also inhibits PTHrP production.
Boras-Granic K, Dann P, Vanhouten J, Karaplis A, Wysolmerski J
Mice lacking the UBC4-testis gene have a delay in postnatal testis development but normal spermatogenesis and fertility.
Bedard N, Hingamp P, Pang Z, Karaplis A, Morales C, Trasler J, Cyr D, Gagnon C, Wing SS
X-linked Hypophosphatemic Rickets (XLH), a Primary Skeletal Dysplasia with Superimposed Rickets
Principal investigators: Karaplis, Andrew C
Keywords: Burosumab; Chondrocytes; Fgf23; Growth Plate; Rickets; Xlh
Targeting Vitamin D Metabolism in Osteoarthritis
Principal investigators: Karaplis, Andrew C
Keywords: Articular Cartilage; Cyp24a1 Enzymatic Activity; Endoplasmic Reticulum Stress; Mtorc1 Activity; Osteoarthritis; Vitamin D
CYP24A1 Enzymatic Activity in FGF23-Mediated Renal Phosphate Wasting Disorders
Principal investigators: Karaplis, Andrew C
Keywords: Cyp24a1; Fgf23; Vitamin D; X-Linked Hypophosphatemic Rickets
Co-targeting parathyroid-hormone related protein (PTHrP) signaling and osteoclast activation to counter breast cancer metastasis to bone
Principal investigators: Kremer, Richard B
Keywords: Bone Metastases; Breast Cancer; Co-Targeted Therapy; Neutralising Antibody; Pthrp
PTHrP and osteoblast biology: Relevance to osteoporosis
Principal investigators: Karaplis, Andrew C
Keywords: Bone; Metabolic Bone Disease; Osteoblast; Osteoporosis; Parathyroid Hormone Related Peptide; Transgenic Mice
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Medicine
- Pediatrics
Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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