Faculty profile

Jacquetta Trasler

ResearcherPediatricsMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Jacquetta Trasler

Researcher

Pediatrics

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
10 publications in the last five years, latest in 2026.
Senior (last) author on 5 recent papers, a sign of leading a research group.
Principal investigator on 6 research grants (6 CIHR), most recently in 2025.
Supervised 3 trainees who won CIHR awards, most recently in 2015.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Dna Methylation Infertility Epigenetics Folate Neurodevelopment Assisted Reproduction Sperm Birth Defects

Latest papers

Advanced Paternal Age Impacts Common Loci in the Sperm and Placenta DNA Methylomes.
Andrology · 2026 · senior author
Frequency, morbidity and equity - the case for increased research on male fertility.
Nature reviews. Urology · 2024
Sperm DNA methylation defects in a new mouse model of the 5,10-methylenetetrahydrofolate reductase 677C>T variant and correction with moderate dose folic acid supplementation.
Molecular human reproduction · 2024 · senior author

All 35 publications

Latest funding

Paternal Age and the Risks of Adverse Perinatal, Neurodevelopmental and Epigenetic Outcomes in Children
CIHR · 2025 · Nominated PI
$1,147,500
Detecting and preventing epigenetic defects and adverse health outcomes associated with assisted reproduction
CIHR · 2023 · Nominated PI
$937,125
The paternal contribution to neurodevelopmental and metabolic outcomes in the child
CIHR · 2017 · Co-investigator
$75,000

All 18 grants and awards

35 publications.

Advanced Paternal Age Impacts Common Loci in the Sperm and Placenta DNA Methylomes.

Barnwell J, Rahimi S, Jones SL, Chan D, Martel J, Abdessamie S, Herba CM, Séguin JR, Fraser WD, Greenwood CMT, Nguyen TV, Montreuil TC, Trasler J

Andrology2026Senior author

DOI: 10.1111/andr.70131 PMID: 41159265

Frequency, morbidity and equity - the case for increased research on male fertility.

Kimmins S, Anderson RA, Barratt CLR, Behre HM, Catford SR, De Jonge CJ, Delbes G, Eisenberg ML, Garrido N, Houston BJ, Jørgensen N, Krausz C, Lismer A, McLachlan RI, Minhas S, Moss T, Pacey A, Priskorn L, Schlatt S, Trasler J, Trasande L, Tüttelmann F, Vazquez-Levin MH, Veltman JA, Zhang F, O'Bryan MK

Nature reviews. Urology2024

DOI: 10.1038/s41585-023-00820-4 PMID: 37828407

Sperm DNA methylation defects in a new mouse model of the 5,10-methylenetetrahydrofolate reductase 677C>T variant and correction with moderate dose folic acid supplementation.

Martínez Duncker Rebolledo E, Chan D, Christensen KE, Reagan AM, Howell GR, Rozen R, Trasler J

Molecular human reproduction2024Senior author

DOI: 10.1093/molehr/gaae008 PMID: 38366926

Transcriptomic integrity of human oocytes used in ARTs: technical and intrinsic factor effects.

Ducreux B, Patrat C, Trasler J, Fauque P

Human reproduction update2024

DOI: 10.1093/humupd/dmad025 PMID: 37697674

Protective and sex-specific effects of moderate dose folic acid supplementation on the placenta following assisted reproduction in mice.

Ihirwe RG, Martel J, Rahimi S, Trasler J

FASEB journal : official publication of the Federation of American Societies for Experimental Biology2023Senior author

DOI: 10.1096/fj.202201428r PMID: 36515682

Gender Disparities in Academic Outcomes Among Graduates of a Canadian MD-PhD Program.

Romero JM, Sorin M, Dankner M, Whittaker H, Rose A, Trasler J, Eisenberg MJ

Clinical and investigative medicine. Medecine clinique et experimentale2023

DOI: 10.25011/cim.v46i1.39965 PMID: 36966388

Prenatal paternal anxiety symptoms predict child DHEA levels and internalizing symptoms during adrenarche.

Jones SL, De Braga V, Caccese C, Lew J, Elgbeili G, Castellanos-Ryan N, Parent S, Muckle G, Herba CM, Fraser WD, Ducharme S, Barnwell J, Trasler J, Séguin JR, Nguyen TV, Montreuil TC

Frontiers in behavioral neuroscience2023

DOI: 10.3389/fnbeh.2023.1217846 PMID: 38239262

Higher incidence of embryonic defects in mouse offspring conceived with assisted reproduction from fathers with sperm epimutations.

Karahan G, Martel J, Rahimi S, Farag M, Matias F, MacFarlane AJ, Chan D, Trasler J

Human molecular genetics2023Senior author

DOI: 10.1093/hmg/ddad160 PMID: 37740387

Capturing sex-specific and hypofertility-linked effects of assisted reproductive technologies on the cord blood DNA methylome.

Rahimi S, Shao X, Chan D, Martel J, Bérard A, Fraser WD, Simon MM, Kwan T, Bourque G, Trasler J

Clinical epigenetics2023Senior author

DOI: 10.1186/s13148-023-01497-7 PMID: 37170172

Medically assisted reproduction and the risk of being born small and very small for gestational age: Assessing prematurity status as an effect modifier.

Gorgui J, Sheehy O, Trasler J, Bérard A

Frontiers in pharmacology2022

DOI: 10.3389/fphar.2022.904885 PMID: 36249815

Paternal Age and the Risks of Adverse Perinatal, Neurodevelopmental and Epigenetic Outcomes in Children

Nominated PICIHR2025Project Grant

Principal investigators: Trasler, Jacquetta M; Montreuil, Tina C; Vélez, Maria Del Pilar

Keywords: Assisted Reproduction; Behavior; Dna Methylation; Epigenetics; Infertility; Neurodevelopment; Paternal Age; Perinatal Outcomes; Sperm

$1,147,500

Detecting and preventing epigenetic defects and adverse health outcomes associated with assisted reproduction

Nominated PICIHR2023Project Grant

Principal investigators: Trasler, Jacquetta M

Keywords: Assisted Reproduction; Birth Defects; Dna Methylation; Embryo; Epigenetics; Folate; Intergenerational; Male Infertility; Mthfr; Sperm

$937,125

The paternal contribution to neurodevelopmental and metabolic outcomes in the child

Co-investigatorCIHR2017Op Gr: NI grants in MRC&Y Health - Pre- and Post-Partum Maternal Mental Health

Principal investigators: Nguyen, Tuong-Vi; Monnier, Patricia O; Zelkowitz, Phyllis

Keywords: Adrenarche; Alcohol; Brain Development; Cognition; Epigenetic; Father; Magnetic Resonance Imaging; Placenta; Psychological Stress; Smoking

$75,000

Assisted Reproductive Technologies and Folic Acid Supplementation: Gene-environment Interactions and Neurodevelopmental and Metabolic Outcomes in Children

Nominated PICIHR2015Environments, Genes and Chronic Disease - LOI

Principal investigators: Trasler, Jacquetta M; MacFarlane, Amanda; Bérard, Anick; Fraser, William D; Monnier, Patricia O; Nguyen, Tuong-Vi; Rozen, Rima; Seguin, Jean R; Walker, Claire-Dominique; Walker, Mark C; Weksberg, Rosanna; Wen, Shi Wu

Keywords: Assisted Reproductive Technologies; Cord Blood; Dna Methylation; Epigenomic Profiling; Folic Acid; Infertility; Metabolic Indices; Neurodevelopment; Placenta

Sex-specific susceptibility windows for fetal origins of adult disease and intergenerational effects

Nominated PICIHR2015Foundation Grant

Principal investigators: Trasler, Jacquetta M

Keywords: Birth Defects; Dna Methylation; Embryogenesis; Epigenetics; Folate; Germ Cells; Infertility; Intergenerational; Oogenesis; Spermatogenesis

$2,449,464

Generational and sex-specific effects of paternal environmental exposures on offspring development health

Co-investigatorCIHR2015Team Grant: DOHaD - Implications for Men, Women, Boys and Girls

Principal investigators: Kimmins, Sarah

Keywords: Chromatin; Developmental Origins Of Health And Disease; Dna Methylation; Epigenomics; Mens Health; Nutrition; Paternal Pre-Conception Health

$1,500,000

Impact of Folic Acid Supplementation on the Epigenome

SupervisorCIHR2015CIHR Fellowship

Principal investigators: Aarabi, Mahmoud

Keywords: Development; Dna Methylation; Epigenetics; Folic Acid; Infertility; Mthfr; Next Generation Sequencing; Pregnancy; Pyrosequencing; Reproduction

$112,500

Sex-specific susceptibility windows for fetal origins of adult disease and transgenerational effects

Nominated PICIHR2013Operating Grant

Principal investigators: Trasler, Jacquetta M

Keywords: Dna Methylation; Epigenetic; Fetus; Folate; Germ Cells; Sex-Specific; Transgenerational

$867,934

Establishment and Stability of DNA Methylation Patterns in the Male Germline

SupervisorCIHR2011Master's Award: Canada Graduate Scholarships

Principal investigators: Farag, Mena

Keywords: Cell Culture; Developmental Genetics; Dna Methyl Transferase (Dnmt); Dna Methylation; Embryogenesis; Epigenetics; Restriction Landscape Genomic Sequencing (Rlgs); Retroviral Transfection; Spermatogenesis; Transgenic Mouse Model

$17,500

Multidimensional Epigenomics Mapping Centre (EMC) at McGill

Co-investigatorCIHR2011CEEHRC Epigenomics Platform - Epigenomic Mapping Centres (EMC)

Principal investigators: Lathrop, Mark; Meaney, Michael J; Pastinen, Tomi

Keywords: Epigenomics

$5,665,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Jacquetta Trasler

Research

Latest papers

Latest funding

Advanced Paternal Age Impacts Common Loci in the Sperm and Placenta DNA Methylomes.

Frequency, morbidity and equity - the case for increased research on male fertility.

Sperm DNA methylation defects in a new mouse model of the 5,10-methylenetetrahydrofolate reductase 677C>T variant and correction with moderate dose folic acid supplementation.

Transcriptomic integrity of human oocytes used in ARTs: technical and intrinsic factor effects.

Protective and sex-specific effects of moderate dose folic acid supplementation on the placenta following assisted reproduction in mice.

Gender Disparities in Academic Outcomes Among Graduates of a Canadian MD-PhD Program.

Prenatal paternal anxiety symptoms predict child DHEA levels and internalizing symptoms during adrenarche.

Higher incidence of embryonic defects in mouse offspring conceived with assisted reproduction from fathers with sperm epimutations.

Capturing sex-specific and hypofertility-linked effects of assisted reproductive technologies on the cord blood DNA methylome.

Medically assisted reproduction and the risk of being born small and very small for gestational age: Assessing prematurity status as an effect modifier.

Frequent collaborators

Sarah Kimmins

Sarah Kimmins

Serge McGraw

Guillaume Bourque

Mathieu Dalvai

Rima Rozen

Patricia Monnier

Gina Muckle

Arnaud Droit

Tuong-Vi Nguyen

Jacquetta Trasler

Gina Muckle

Bernard Robaire

Ravi Retnakaran

Zhong-Cheng Luo

Robert Gagnon

Simon Ducharme

Pablo Nepomnaschy

Natalie Castellanos Ryan

Tamara Cohen

Vanessa Dumeaux

April Rose

Rosanna Weksberg

Haim Abenhaim

Michael Brudno

Tomi Pastinen

Stephen Lye

Stephanie Atkinson

Cindy-Lee Dennis

Nada Jabado