Faculty profile

David Goltzman

ResearcherMedicineMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

David Goltzman

Researcher

Medicine

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
47 publications in the last five years, latest in 2026.
Senior (last) author on 6 recent papers, a sign of leading a research group.
Principal investigator on 4 research grants (4 CIHR), most recently in 2016.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

162

Publications

2,333

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Bone Formation Calcium Sensing Receptor Osteoblasts Pth And Pthrp Vitamin D Biomarkers Epidemiology Genetics

Latest papers

Fractures at virtually all sites are associated with adverse outcomes: an observational study
Journal of Bone and Mineral Research · 2026
Fracture risk scores using output from an opportunistic screen of low bone density from conventional X-ray
Journal of Bone and Mineral Research · 2026
An explainable machine learning approach to predict fragility fractures and the identification of important features
Scientific Reports · 2026

All 162 publications

Latest funding

OsNET: The Canadian Bone Health Research Network
CIHR · 2023 · Co-investigator
$1,200,000
The association between denosumab and the risk of atypical femoral fractures in osteoporosis management
CIHR · 2023 · Co-investigator
$179,776
Effectiveness and Safety of Long-term Antiresorptive Treatment for Osteoporosis in Canada: Improving Shared Decision Making
CIHR · 2023 · Co-investigator
$715,275

All 17 grants and awards

From the 150 most recent of 162 publications.

Fractures at virtually all sites are associated with adverse outcomes: an observational study

Alajlouni DA, Alarkawi D, Tran TS, Prior JC, Kovacs CS, Berger C, Hanley DA, Goltzman D, Adachi JD, Langsetmo L

Journal of Bone and Mineral Research20262 citations

DOI: 10.1093/jbmr/zjag052

Fracture risk scores using output from an opportunistic screen of low bone density from conventional X-ray

Syme CA, Cicero MD, Adachi JD, Berger C, Morin SN, Goltzman D, Bilbily A

Journal of Bone and Mineral Research20262 citations

DOI: 10.1093/jbmr/zjaf113

An explainable machine learning approach to predict fragility fractures and the identification of important features

Borhan S, Papaioannou A, Adachi J, Acharya S, Morin SN, Goltzman D, Hanley DA, Berger C, Thabane L, Raina P

Scientific Reports20261 citations

DOI: 10.1038/s41598-026-49494-z

Active vitamin D protects against osteoporosis by promoting VDR-dependent CDK2 transcription and P27 degradation.

Xu F, Liu Q, Huang M, Wang J, Goltzman D, Gu B, Miao D

European journal of endocrinology2026

DOI: 10.1093/ejendo/lvag152 PMID: 42592858

A meta-analysis of smoking and fracture risk to update the FRAX® tool.

Schini M, Johansson H, Harvey NC, Lorentzon M, Liu E, Vandenput L, Leslie WD, Åkesson KE, Anderson FA, Azagra-Ledesma R, Bager CL, Beaudart C, Bischoff-Ferrari HA, Biver E, Bruyère O, Cauley JA, Center JR, Chapurlat R, Christiansen C, Cooper C, Crandall CJ, Cummings SR, da Silva JAP, Dawson-Hughes B, Diez-Perez A, Dufour AB, Eisman JA, Elders PJM, Ferrari S, Fujita Y, Fujiwara S, Glüer CC, Goldshtein I, Goltzman D, Gudnason V, Hall J, Hans D, Hoff M, Hollick RJ, Huisman M, Iki M, Ish-Shalom S, Jones G, Karlsson MK, Khosla S, Kiel DP, Koh WP, Koromani F, Kotowicz MA, Kröger H, Kwok T, Lamy O, Langhammer A, Larijani B, Lippuner K, McGuigan FEA, Mellström D, Merlijn T, Nguyen TV, Nordström A, Nordström P, Obermayer-Pietsch B, Ohlsson C, O'Neill TW, Orwoll ES, Pasco JA, Rivadeneira F, Schei B, Schott AM, Shiroma EJ, Siggeirsdottir K, Simonsick EM, Sornay-Rendu E, Sund R, Swart KM, Szulc P, Tamaki J, Torgerson DJ, van Schoor NM, van Staa TP, Vila J, Wareham NJ, Wright NC, Yoshimura N, Zillikens M, Zwart M, Kanis JA, McCloskey EV

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2026

DOI: 10.1007/s00198-026-07853-6 PMID: 41779026

The distinct roles of PTHrP and PTH1R in long bone growth and digit formation.

Shimoide T, Nguyen-Yamamoto L, Canaff L, Kawao N, Takada Y, Kaji H, Enomoto A, Goltzman D

JBMR plus2026Senior author

DOI: 10.1093/jbmrpl/ziag119 PMID: 42630974

Correction: A meta-analysis of previous falls and subsequent fracture risk in cohort studies.

Vandenput L, Johansson H, McCloskey EV, Liu E, Schini M, Åkesson KE, Anderson FA, Azagra R, Bager CL, Beaudart C, Bischoff-Ferrari HA, Biver E, Bruyère O, Cauley JA, Center JR, Chapurlat R, Christiansen C, Cooper C, Crandall CJ, Cummings SR, da Silva JAP, Dawson-Hughes B, Diez-Perez A, Dufour AB, Eisman JA, Elders PJM, Ferrari S, Fujita Y, Fujiwara S, Glüer CC, Goldshtein I, Goltzman D, Gudnason V, Hall J, Hans D, Hoff M, Hollick RJ, Huisman M, Iki M, Ish-Shalom S, Jones G, Karlsson MK, Khosla S, Kiel DP, Koh WP, Koromani F, Kotowicz MA, Kröger H, Kwok T, Lamy O, Langhammer A, Larijani B, Lippuner K, McGuigan FEA, Mellström D, Merlijn T, Nguyen TV, Nordström A, Nordström P, O'Neill TW, Obermayer-Pietsch B, Ohlsson C, Orwoll ES, Pasco JA, Rivadeneira F, Schott AM, Shiroma EJ, Siggeirsdottir K, Simonsick EM, Sornay-Rendu E, Sund R, Swart KMA, Szulc P, Tamaki J, Torgerson DJ, van Schoor NM, van Staa TP, Vila J, Wareham NJ, Wright NC, Yoshimura N, Zillikens MC, Zwart M, Harvey NC, Lorentzon M, Leslie WD, Kanis JA

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2026

DOI: 10.1007/s00198-026-07957-z PMID: 41874643

Predictive value of BMD for hip and other fractures: a meta-analysis to update FRAX.

Kanis JA, McCloskey EV, Johansson H, Liu E, Åkesson KE, Anderson FA, Azagra-Ledesma R, Bager CL, Beaudart C, Bischoff-Ferrari HA, Biver E, Bruyère O, Cauley JA, Center JR, Chapurlat R, Christiansen C, Cooper C, Crandall CJ, Cummings SR, da Silva JAP, Dawson-Hughes B, Diez-Perez A, Dufour AB, Eisman JA, Elders PJM, Ferrari S, Fujita Y, Fujiwara S, Glüer CC, Goldshtein I, Goltzman D, Gudnason V, Hall J, Hans D, Hoff M, Hollick RJ, Huisman M, Iki M, Ish-Shalom S, Jones G, Karlsson MK, Khosla S, Kiel DP, Koh WP, Koromani F, Kotowicz MA, Kröger H, Kwok T, Lamy O, Langhammer A, Larijani B, Lippuner K, Mellström D, Merlijn T, Nordström A, Nordström P, O Neill TW, Obermayer-Pietsch B, Ohlsson C, Orwoll ES, Pasco JA, Rivadeneira F, Schei B, Schott AM, Shiroma EJ, Siggeirsdottir K, Simonsick EM, Sornay-Rendu E, Sund R, Swart K, Szulc P, Tamaki J, Torgerson DJ, van Schoor NM, van Staa TP, Vila J, Wareham NJ, Wright NC, Yoshimura N, Zillikens MC, Zwart M, Harvey NC, Lorentzon M, Leslie WD

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2026

DOI: 10.1007/s00198-026-07925-7 PMID: 41820630

Liver-derived, circulating plasma fibronectin regulates trabecular bone mass and bone formation in adult male mice and its levels in sera associates with bone density in aging men.

Mahmoodi M, Berger C, Nabavi MH, Xiao Y, Canaff L, Pata M, Li J, Ferron M, Murshed M, Goltzman D, Morin SN, Kaartinen MT

Matrix biology : journal of the International Society for Matrix Biology2026

DOI: 10.1016/j.matbio.2025.12.001 PMID: 41365401

Effect of inactivation of the USP19 deubiquitinase gene in mice on important phenotypes of aging.

Sheng K, Coyne ES, Bédard N, Lu E, Goltzman D, Haglund L, Wing SS

The journals of gerontology. Series A, Biological sciences and medical sciences2026

DOI: 10.1093/gerona/glag138 PMID: 42225593

OsNET: The Canadian Bone Health Research Network

Co-investigatorCIHR2023Network Grants in Skin Health, Bone Health, and Muscular Dystrophy - Bone Health

Principal investigators: Boyd, Steven K; Cheung, Angela M; Morin, Suzanne N

Keywords: Advanced Imaging; Bone Health; Clinical Guidelines; Diagnostics; Fracture Prediction; Knowledge Transfer; Musculoskeletal; Network; Personalized Medicine; Research

$1,200,000

The association between denosumab and the risk of atypical femoral fractures in osteoporosis management

Co-investigatorCIHR2023Project Grant

Principal investigators: Yu, Oriana Hoi Yun

Keywords: Atypical Femoral Fractures; Denosumab; Osteoporosis; Population Cohort Study

$179,776

Effectiveness and Safety of Long-term Antiresorptive Treatment for Osteoporosis in Canada: Improving Shared Decision Making

Co-investigatorCIHR2023Project Grant

Principal investigators: Morin, Suzanne N; Leslie, William D; Lix, Lisa M

Keywords: Administrative Data Analysis; Antiresorptive Drug Therapy; Bone Mineral Density; Cohort Study; Fractures; Osteoporosis; Safety; Shared Decision Making

$715,275

Vitamin D signaling in the thymic microenvironment and its functional cooperation with Aire.

Co-investigatorCIHR2021Project Grant

Principal investigators: White, John H; Melichar, Heather

Keywords: Aire; Functional Genomics; Thymus; Transcriptional Regulation; Vitamin D

$910,350

Ethnic Differences and Geographical Variations in Osteoporosis and Fractures in the Canadian Population

Co-investigatorCIHR2018Catalyst Grant: Analysis of CLSA Data

Principal investigators: Morin, Suzanne N

Keywords: Aging; Bone Mineral Density; Ethnicity; Fracture Risk Assessment; Fractures; Frailty; Indigenous Canadians; Nutrition; Osteoporosis; Socio-Environmental Factors

$69,989

Follicle-stimulating hormone regulation of bone physiology and pathophysiology

Co-investigatorCIHR2017Project Grant

Principal investigators: Bernard, Daniel J

Keywords: Conditional Knockout; Cre-Lox; Follicle-Stimulating Hormone; Fsh Receptor; Granulosa Cells; Mouse; Osteoclasts; Osteoporosis

$810,900

Causal Proteins for Osteoporosis

Co-investigatorCIHR2016Project Grant

Principal investigators: Richards, Brent

Keywords: Animal Models Of Osteoporosis; Bioinformatics; Functional Genomics; Genetic Epidemiology; Genetic Fine Mapping; Genetics; Genomics; Osteoporotic Fracture

$1,123,815

The Canadian Multicentre Osteoporosis Study

Nominated PICIHR2016Project Grant

Principal investigators: Goltzman, David; Kreiger, Nancy

Keywords: Biomarkers; Epidemiology; Genetics; Imaging; Nutrition; Osteoporosis; Risk Factors

$100,000

Analysis of the Anabolic Activity of Hormones Regulating Skeletal Metabolism

Nominated PICIHR2016Project Grant

Principal investigators: Goltzman, David

Keywords: Bone Formation; Calcium Sensing Receptor; Osteoblasts; Pth And Pthrp; Vitamin D

$646,425

The effect of dietary calcium intake as compared to calcium supplementation on vascular and bone health in postmenopausal women

Co-investigatorCIHR2013Operating Grant

Principal investigators: Morin, Suzanne N; Daskalopoulou, Stella S

Keywords: Bone Health; Calcium Supplements; Cardiovascular Health; Dietary Calcium; Menopause; Micronutrients; Randomized Control Trial; Vitamin D

$483,340

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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David Goltzman

Research

Latest papers

Latest funding

Fractures at virtually all sites are associated with adverse outcomes: an observational study

Fracture risk scores using output from an opportunistic screen of low bone density from conventional X-ray

An explainable machine learning approach to predict fragility fractures and the identification of important features

Active vitamin D protects against osteoporosis by promoting VDR-dependent CDK2 transcription and P27 degradation.

A meta-analysis of smoking and fracture risk to update the FRAX&#xae; tool.

The distinct roles of PTHrP and PTH1R in long bone growth and digit formation.

Correction: A meta-analysis of previous falls and subsequent fracture risk in cohort studies.

Predictive value of BMD for hip and other fractures: a meta-analysis to update FRAX.

Liver-derived, circulating plasma fibronectin regulates trabecular bone mass and bone formation in adult male mice and its levels in sera associates with bone density in aging men.

Effect of inactivation of the USP19 deubiquitinase gene in mice on important phenotypes of aging.

Frequent collaborators

Jonathan Derrick Adachi

Alexandra Papaioannou

Nancy Kreiger

Andrew Karaplis

Lawrence Joseph

Jerilynn Prior

Suzanne Morin

Elin Grundberg

George Ioannidis

Lehana Thabane

Elham Rahme

René St-Arnaud

Jacques Genest

Mitchell Levine

Lauren Burt

Kaberi Dasgupta

Suhad Ali

Adele Changoor

Sirui Zhou

Despoina Manousaki

Zhiwei Gao

Tomi Pastinen

Philippe Gros

Richard Kremer

Celia Greenwood

Mathieu Ferron

Damiano Pasini

Kaberi Dasgupta

Annik Prat

Lisbet Haglund

Steven Boyd

A meta-analysis of smoking and fracture risk to update the FRAX® tool.