Faculty profile

Bruno Giros

ResearcherPsychiatryMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Bruno Giros

Researcher

Psychiatry

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
12 publications in the last five years, latest in 2025.
Senior (last) author on 3 recent papers, a sign of leading a research group.
Principal investigator on 8 research grants (6 CIHR, 2 NSERC), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Dopamine Receptors Dopamine In Vivo Calcium Imaging Behavioral Analysis Chemogenetic Conditional Knockout Inflammation Mental Health

Latest papers

Evidence of microglial involvement in the childhood abuse-associated increase in perineuronal nets in the ventromedial prefrontal cortex.
Brain, behavior, and immunity · 2025
Mesolimbic dopamine neurons drive infradian rhythms in sleep-wake and heightened activity state.
Science advances · 2025
Role of the locus coeruleus-noradrenergic system in stress-related psychopathology and resilience: Clinical and pre-clinical evidences.
Neuroscience and biobehavioral reviews · 2024

All 39 publications

Latest funding

Dopaminergic activation of microglia through D1 and D2 receptors controls inflammatory state and behavior
CIHR · 2024 · Nominated PI
$1,174,275
Noradrenergic control of vulnerability to chronic stress: novel mechanisms and targets
CIHR · 2019 · Nominated PI
$883,576
Understanding the complexity of dopamine transmission: Specific role of the neurons co-expressing D1 and D2 receptors.
CIHR · 2018 · Nominated PI
$872,100

All 9 grants and awards

39 publications.

Evidence of microglial involvement in the childhood abuse-associated increase in perineuronal nets in the ventromedial prefrontal cortex.

Belliveau C, Rahimian R, Fakhfouri G, Hosdey C, Simard S, Davoli MA, Mirault D, Giros B, Turecki G, Mechawar N

Brain, behavior, and immunity2025

DOI: 10.1016/j.bbi.2024.12.013 PMID: 39672240

Mesolimbic dopamine neurons drive infradian rhythms in sleep-wake and heightened activity state.

Markam PS, Bourguignon C, Zhu L, Ward B, Darvas M, Sabatini PV, Kokoeva MV, Giros B, Storch KF

Science advances2025

DOI: 10.1126/sciadv.ado9965 PMID: 39742489

Role of the locus coeruleus-noradrenergic system in stress-related psychopathology and resilience: Clinical and pre-clinical evidences.

Slavova D, Ortiz V, Blaise M, Bairachnaya M, Giros B, Isingrini E

Neuroscience and biobehavioral reviews2024

DOI: 10.1016/j.neubiorev.2024.105925 PMID: 39427811

Proteomic evidence of depression-associated astrocytic dysfunction in the human male olfactory bulb.

Rahimian R, Perlman K, Fakhfouri G, Mpai R, Richard VR, Hercher C, Penney L, Davoli MA, Nagy C, Zahedi RP, Borchers CH, Giros B, Turecki G, Mechawar N

Brain, behavior, and immunity2024

DOI: 10.1016/j.bbi.2024.08.016 PMID: 39128570

Striatal projection neurons coexpressing dopamine D1 and D2 receptors modulate the motor function of D1- and D2-SPNs.

Bonnavion P, Varin C, Fakhfouri G, Martinez Olondo P, De Groote A, Cornil A, Lorenzo Lopez R, Pozuelo Fernandez E, Isingrini E, Rainer Q, Xu K, Tzavara E, Vigneault E, Dumas S, de Kerchove d'Exaerde A, Giros B

Nature neuroscience2024Senior author

DOI: 10.1038/s41593-024-01694-4 PMID: 38965445

Chondroitin sulfate glycan sulfation patterns influence histochemical labeling of perineuronal nets: a comparative study of interregional distribution in human and mouse brain.

Belliveau C, Théberge S, Netto S, Rahimian R, Fakhfouri G, Hosdey C, Davoli MA, Hendrickson A, Hao K, Giros B, Turecki G, Alonge KM, Mechawar N

Glycobiology2024

DOI: 10.1093/glycob/cwae049 PMID: 38995945

Chondroitin sulfate glycan sulfation patterns influence histochemical labeling of perineuronal nets: a comparative study of interregional distribution in human and mouse brain.

Belliveau C, Théberge S, Netto S, Rahimian R, Fakhfouri G, Hosdey C, Davoli MA, Hendrickson A, Hao K, Giros B, Turecki G, Alonge KM, Mechawar N

bioRxiv : the preprint server for biology2024

DOI: 10.1101/2024.02.09.579711 PMID: 38948769

Nucleus accumbens D1- and D2-expressing neurons control the balance between feeding and activity-mediated energy expenditure.

Walle R, Petitbon A, Fois GR, Varin C, Montalban E, Hardt L, Contini A, Angelo MF, Potier M, Ortole R, Oummadi A, De Smedt-Peyrusse V, Adan RA, Giros B, Chaouloff F, Ferreira G, de Kerchove d'Exaerde A, Ducrocq F, Georges F, Trifilieff P

Nature communications2024

DOI: 10.1038/s41467-024-46874-9 PMID: 38514654

Persistent extrasynaptic hyperdopaminergia in the mouse hippocampus induces plasticity and recognition memory deficits reversed by the atypical antipsychotic sulpiride.

Rocchetti J, Fasano C, Dal-Bo G, Guma E, El Mestikawy S, Wong TP, Fakhfouri G, Giros B

PloS one2023Senior author

DOI: 10.1371/journal.pone.0289770 PMID: 37624765

The neurons that drive infradian sleep-wake and mania-like behavioral rhythms.

Markam PS, Bourguignon C, Zhu L, Darvas M, Sabatini PV, Kokoeva MV, Giros B, Storch KF

bioRxiv : the preprint server for biology2023

DOI: 10.1101/2023.11.14.566955 PMID: 38014299

Dopaminergic activation of microglia through D1 and D2 receptors controls inflammatory state and behavior

Nominated PICIHR2024Project Grant

Principal investigators: Giros, Bruno J

Keywords: Behavioral Analysis; Chemogenetic; Conditional Knockout; Dopamine Receptors; Inflammation; Mental Health; Microglial Cells

$1,174,275

Noradrenergic control of vulnerability to chronic stress: novel mechanisms and targets

Nominated PICIHR2019Project Grant

Principal investigators: Giros, Bruno J

Keywords: Antidepressant; Chronic Social Defeat; Chronic Stress; Depression; Dopamine; In Vivo Calcium Imaging; Noradrenaline; Noradrenergic Receptors; Resiliency

$883,576

Understanding the complexity of dopamine transmission: Specific role of the neurons co-expressing D1 and D2 receptors.

Nominated PICIHR2018Project Grant

Principal investigators: Giros, Bruno J

Keywords: Addiction; Cognitive Functions; Dopamine; Dopamine Receptors; In Vivo Calcium Imaging; Intersectionel Genetic; Medium Spiny Neurons; Motor Functions

$872,100

A pharmacological approach to reduce cognitive deficits in psychosis: Targeting of the dopamine D1 receptors.

Nominated PICIHR2013Operating Grant

Principal investigators: Giros, Bruno J

Keywords: Cognitive Deficits; Pharmacology; Pre-Clinical Models; Schizophrenia

$679,294

Ultracentrifugation for the biochemical characterization of biomarkers involved in neurobiological functions

Co-investigatorNSERC2013Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Ma, Weiya

$78,654

CRC Tier 1

Nominated PICIHR2013Canada Research Chairs - CIHR Funded - Tier 1

Principal investigators: Giros, Bruno J

Keywords: Crc

$1,400,000

Study of the Vesicular Monoamine Transporter: Role and Function

Principal investigatorNSERC2012Discovery Grants Program - Individual

Principal investigators: Giros, Bruno

$130,000

Study of the vesicular monoamine transporter: role and function

Principal investigatorNSERC2011Discovery Grants Program - Individual

Principal investigators: Giros, Bruno

$30,000

Regulation of the Dopamine Transporter functional activity. Identification of new targets.

Nominated PICIHR2010Operating Grant

Principal investigators: Giros, Bruno J

Keywords: Dopamine Transporter; Proteomic

$780,085

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Bruno Giros

Research

Latest papers

Latest funding

Evidence of microglial involvement in the childhood abuse-associated increase in perineuronal nets in the ventromedial prefrontal cortex.

Mesolimbic dopamine neurons drive infradian rhythms in sleep-wake and heightened activity state.

Role of the locus coeruleus-noradrenergic system in stress-related psychopathology and resilience: Clinical and pre-clinical evidences.

Proteomic evidence of depression-associated astrocytic dysfunction in the human male olfactory bulb.

Striatal projection neurons coexpressing dopamine D1 and D2 receptors modulate the motor function of D1- and D2-SPNs.

Chondroitin sulfate glycan sulfation patterns influence histochemical labeling of perineuronal nets: a comparative study of interregional distribution in human and mouse brain.

Chondroitin sulfate glycan sulfation patterns influence histochemical labeling of perineuronal nets: a comparative study of interregional distribution in human and mouse brain.

Nucleus accumbens D1- and D2-expressing neurons control the balance between feeding and activity-mediated energy expenditure.

Persistent extrasynaptic hyperdopaminergia in the mouse hippocampus induces plasticity and recognition memory deficits reversed by the atypical antipsychotic sulpiride.

The neurons that drive infradian sleep-wake and mania-like behavioral rhythms.

Dopaminergic activation of microglia through D1 and D2 receptors controls inflammatory state and behavior

Noradrenergic control of vulnerability to chronic stress: novel mechanisms and targets

Understanding the complexity of dopamine transmission: Specific role of the neurons co-expressing D1 and D2 receptors.

A pharmacological approach to reduce cognitive deficits in psychosis: Targeting of the dopamine D1 receptors.

Ultracentrifugation for the biochemical characterization of biomarkers involved in neurobiological functions

CRC Tier 1

Study of the Vesicular Monoamine Transporter: Role and Function

Study of the vesicular monoamine transporter: role and function

Regulation of the Dopamine Transporter functional activity. Identification of new targets.

Frequent collaborators

Bruno Giros

Naguib Mechawar

Gustavo Turecki

Kai-Florian Storch

Salah El Mestikawy

Corina Nagy

Sylvain Williams

Eduardo Chachamovich

Jane Foster

Daniel Levesque