This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
TULIPs decorate the three-dimensional genome of PFA ependymoma.
Cell · 2024
Uncovering a mammalian neural-specific poly(A) binding protein with unique properties.
Genes & development · 2023
3D chromatin remodeling potentiates transcriptional programs driving cell invasion.
Proceedings of the National Academy of Sciences of the United States of America · 2022
Latest funding
- $1,338,908
Investigating and targeting pathogenic variants in DICER1-related tumour predisposition
CIHR · 2026 · Co-investigator
- $1,105,426
Single-cell epigenome profiling of pediatric high-grade gliomas to detect therapeutic vulnerabilities
CIHR · 2026 · Nominated PI
- $1,243,126
Unraveling how de novo germline H3.3 mutations promote neurodegeneration and disease
CIHR · 2024 · Co-investigator
4 publications.
TULIPs decorate the three-dimensional genome of PFA ependymoma.
Johnston MJ, Lee JJY, Hu B, Nikolic A, Hasheminasabgorji E, Baguette A, Paik S, Chen H, Kumar S, Chen CCL, Jessa S, Balin P, Fong V, Zwaig M, Michealraj KA, Chen X, Zhang Y, Varadharajan S, Billon P, Juretic N, Daniels C, Rao AN, Giannini C, Thompson EM, Garami M, Hauser P, Pocza T, Ra YS, Cho BK, Kim SK, Wang KC, Lee JY, Grajkowska W, Perek-Polnik M, Agnihotri S, Mack S, Ellezam B, Weil A, Rich J, Bourque G, Chan JA, Yong VW, Lupien M, Ragoussis J, Kleinman C, Majewski J, Blanchette M, Jabado N, Taylor MD, Gallo M
Uncovering a mammalian neural-specific poly(A) binding protein with unique properties.
Sharma S, Kajjo S, Harra Z, Hasaj B, Delisle V, Ray D, Gutierrez RL, Carrier I, Kleinman C, Morris Q, Hughes TR, McInnes R, Fabian MR
3D chromatin remodeling potentiates transcriptional programs driving cell invasion.
Lebeau B, Jangal M, Zhao T, Wong CK, Wong N, Cañedo EC, Hébert S, Aguilar-Mahecha A, Chabot C, Buchanan M, Catterall R, McCaffrey L, Deblois G, Kleinman C, Park M, Basik M, Witcher M
Digital Display Precision Predictor: the prototype of a global biomarker model to guide treatments with targeted therapy and predict progression-free survival.
Lazar V, Magidi S, Girard N, Savignoni A, Martini JF, Massimini G, Bresson C, Berger R, Onn A, Raynaud J, Wunder F, Berindan-Neagoe I, Sekacheva M, Braña I, Tabernero J, Felip E, Porgador A, Kleinman C, Batist G, Solomon B, Tsimberidou AM, Soria JC, Rubin E, Kurzrock R, Schilsky RL
Investigating and targeting pathogenic variants in DICER1-related tumour predisposition
Principal investigators: Foulkes, William D; Fabian, Marc R; Huang, Sidong
Keywords: Cancer Predisposition Syndrome; Dicer1-Related Tumour Predisposition; Microrna Processing; Sarcoma
Single-cell epigenome profiling of pediatric high-grade gliomas to detect therapeutic vulnerabilities
Principal investigators: Kleinman, Claudia L; Binan, Loic; Pathania, Manavendra S
Keywords: 3d Genome; Computational Biology; Epigenome Profiling; High-Grade Gliomas; Mouse Models; Pediatric Brain Tumors; Perturb-Seq; Single-Cell
Unraveling how de novo germline H3.3 mutations promote neurodegeneration and disease
Principal investigators: Jabado, Nada
Keywords: Dna Methylation; Genetically Modified Animals; Histone Marks; Muscular Dystrophy; Neurobehavioural; Neurodevelopment; Obesity; Organoids; Urinary Tract Dysfunction
Targeting vulnerabilities in oncohistone-mediated gliomas
Principal investigators: Jabado, Nada
Keywords: 3d Chromatin; Epigenetics; Histone Mutations; Mouse Modeling; Pediatric Brain Tumours; Signaling Pathways; Targeted Therapies
Investigating and targeting pathogenic variants in DICER1 tumour predisposition syndrome
Principal investigators: Foulkes, William D; Fabian, Marc R; Huang, Sidong
Keywords: Cancer Predisposition Syndrome; Dicer1 Tumour Predisposition Syndrome; Microrna Processing; Sarcoma
Cell of origin dependencies in pediatric high-grade gliomas
Principal investigators: Kleinman, Claudia L; Jabado, Nada; Pathania, Manavendra S
Keywords: Brain Development; Epigenomics; Integrative Genomics; Mouse Models; Oncohistones; Pediatric Brain Tumors; Single-Cell Epigenomics; Single-Cell Transcriptomics
Identification of the mechanisms underlying the early stages of leukemogenesis in human hematopoietic stem cells.
Principal investigators: Eppert, Kolja
Keywords: Acute Myeloid Leukemia; Hematopoiesis; Hematopoietic Stem Cell; Pre-Leukemia; Stem Cell Biology
Integrating Multi-Omics, Multi-Modal Neuroimaging and Artificial Intelligence for Biologically-defined Staging and Stratification in the Alzheimer's Disease spectrum
Principal investigators: Iturria Medina, Yasser
Keywords: Artificial Intelligence; Daily Clinical Practice; Identifying Disease Stages And Variants; Multi-Omics And Multi-Modal Brain Imaging; Open-Access Software; Personalized Medicine In Neurodegeneration
A system for automated high-content screening and laser manipulation of single cells.
Principal investigators: Costantino, Santiago
Computational single-cell analysis of developmental programs disrupted in pediatric tumours
Principal investigators: Jessa, Selin Naheed
Keywords: Bioinformatics; Brain Development; Brain Tumours; Childhood Cancer; Gene Expression; Single-Cell Transcriptomics
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Human Genetics
- Biochemistry and Molecular Biology
- Oncology
- Chemical Engineering
- Medicine
- McGill Cancer Centre
- Social Studies of Medicine
- Other
Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Pierre Billon
Biochemistry and Molecular Biology
1 shared papers, latest 2024
Michael Witcher
Oncology
1 shared papers, latest 2022
Nada Jabado
Pediatrics
1 shared papers, latest 2024
Gerald Batist
Medicine
1 shared papers, latest 2021
Mathieu Lupien
Medical Biophysics
1 shared papers, latest 2024
Gerald Batist
Chemical Engineering
1 shared papers, latest 2021
Mathieu Blanchette
Faculty
1 shared papers, latest 2024
Morag Park
Oncology
1 shared papers, latest 2022
Jacek Majewski
Human Genetics
1 shared papers, latest 2024
Guillaume Bourque
Human Genetics
1 shared papers, latest 2024
Mark Basik
Social Studies of Medicine
1 shared papers, latest 2022
Marco Gallo
Biochemistry and Molecular Biology
1 shared papers, latest 2024
Luke McCaffrey
McGill Cancer Centre
1 shared papers, latest 2022
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