Faculty profile

Marco Gallo

ResearcherBiochemistry and Molecular BiologyUniversity of Calgary

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Calgary directory, so their courses may be missing. Find their university profile.

Marco Gallo

Researcher

Biochemistry and Molecular Biology

Health Sciences

University of Calgary

Calgary, Alberta, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
14 publications in the last five years, latest in 2026.
Senior (last) author on 7 recent papers, a sign of leading a research group.
Principal investigator on 6 research grants (5 CIHR, 1 NSERC), most recently in 2022.
Supervised 1 trainee who won CIHR awards, most recently in 2019.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Cancer Epigenomics Crc Cancer Stem Cells Chromatin Epigenetics Glioblastoma Self-Renewal

Latest papers

H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs.
Nature genetics · 2026
EZHIP boosts neuronal-like synaptic gene programs and depresses polyamine metabolism.
Acta neuropathologica communications · 2025 · senior author
Spatial epigenomic niches underlie glioblastoma cell state plasticity.
bioRxiv : the preprint server for biology · 2025 · senior author

All 25 publications

Latest funding

Recurrent 3D genome features in PFA ependymoma
CIHR · 2022 · Nominated PI
$390,000
Canada Reseach Chair - Tier 2
CIHR · 2021 · Nominated PI
$500,000
Determining the impact of inosine-producing microbes in promoting the efficacy and modulating toxicity of immune checkpoint blockade therapy in cancer.
CIHR · 2021 · Co-investigator
$975,376

All 9 grants and awards

25 publications.

H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs.

Krug B, Hu B, Chen H, Negrón-Lomas C, Chen X, El Mouatani A, Gretarsson KH, Ptack A, Deshmukh S, Kabir N, Jawhar W, Andrade AF, Jabbour E, Harutyunyan AS, Wang X, Taylor R, Lee JJY, Hulswit M, Faury D, Russo C, Xu X, Yang J, Baguette A, Dahl NA, Weil AG, Ellezam B, Dali R, Blanchette M, Wilson K, Garcia BA, Soni RK, Gallo M, Taylor MD, Kleinman CL, Majewski J, Jabado N, Lu C

Nature genetics2026

DOI: 10.1038/s41588-026-02586-y PMID: 42151415

EZHIP boosts neuronal-like synaptic gene programs and depresses polyamine metabolism.

Hasheminasabgorji E, Chen HM, Gatesman TA, Younes ST, Nobles GA, Jaryani F, Mao H, Yu K, Deneen B, Yong W, Taylor MD, Agnihotri S, Gallo M

Acta neuropathologica communications2025Senior author

DOI: 10.1186/s40478-025-02141-6 PMID: 41204377

Spatial epigenomic niches underlie glioblastoma cell state plasticity.

Kint S, Younes ST, Bao S, Long G, Wouters D, Stephenson E, Lou X, Zhong M, Zhang D, Su G, Enninful A, Yang M, Chen HM, Ellestad K, Anderson C, Moliterno J, Kelly J, Chan JA, Sifrim A, Zhou J, Nikolic A, Fan R, Gallo M

bioRxiv : the preprint server for biology2025Senior author

DOI: 10.1101/2025.05.09.653178 PMID: 40463280

CASCADES, a novel SOX2 super-enhancer-associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma.

Shahzad U, Nikolopoulos M, Li C, Johnston M, Wang JJ, Sabha N, Varn FS, Riemenschneider A, Krumholtz S, Krishnamurthy PM, Smith CA, Karamchandani J, Watts JK, Verhaak RGW, Gallo M, Rutka JT, Das S

Molecular oncology2025

DOI: 10.1002/1878-0261.13735 PMID: 39323013

3D genome topology distinguishes molecular subgroups of medulloblastoma.

Lee JJY, Johnston MJ, Farooq H, Chen HM, Younes ST, Suarez R, Zwaig M, Juretic N, Weiss WA, Ragoussis J, Jabado N, Taylor MD, Gallo M

American journal of human genetics2024Senior author

DOI: 10.1016/j.ajhg.2024.10.003 PMID: 39481374

TULIPs decorate the three-dimensional genome of PFA ependymoma.

Johnston MJ, Lee JJY, Hu B, Nikolic A, Hasheminasabgorji E, Baguette A, Paik S, Chen H, Kumar S, Chen CCL, Jessa S, Balin P, Fong V, Zwaig M, Michealraj KA, Chen X, Zhang Y, Varadharajan S, Billon P, Juretic N, Daniels C, Rao AN, Giannini C, Thompson EM, Garami M, Hauser P, Pocza T, Ra YS, Cho BK, Kim SK, Wang KC, Lee JY, Grajkowska W, Perek-Polnik M, Agnihotri S, Mack S, Ellezam B, Weil A, Rich J, Bourque G, Chan JA, Yong VW, Lupien M, Ragoussis J, Kleinman C, Majewski J, Blanchette M, Jabado N, Taylor MD, Gallo M

Cell2024Senior author

DOI: 10.1016/j.cell.2024.06.023 PMID: 38986619

Cancer stem cell hypothesis 2.0 in glioblastoma: Where are we now and where are we going?

Sloan AR, Silver DJ, Kint S, Gallo M, Lathia JD

Neuro-oncology2024

DOI: 10.1093/neuonc/noae011 PMID: 38394444

Linked-read based analysis of the medulloblastoma genome.

Zwaig M, Johnston MJ, Lee JJY, Farooq H, Gallo M, Jabado N, Taylor MD, Ragoussis J

Frontiers in oncology2023

DOI: 10.3389/fonc.2023.1221611 PMID: 37576901

macroH2A2 antagonizes epigenetic programs of stemness in glioblastoma.

Nikolic A, Maule F, Bobyn A, Ellestad K, Paik S, Marhon SA, Mehdipour P, Lun X, Chen HM, Mallard C, Hay AJ, Johnston MJ, Gafuik CJ, Zemp FJ, Shen Y, Ninkovic N, Osz K, Labit E, Berger ND, Brownsey DK, Kelly JJ, Biernaskie J, Dirks PB, Derksen DJ, Jones SJM, Senger DL, Chan JA, Mahoney DJ, De Carvalho DD, Gallo M

Nature communications2023Senior author

DOI: 10.1038/s41467-023-38919-2 PMID: 37244935

Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor-Initiating Cells.

Mirzaei R, D'Mello C, Liu M, Nikolic A, Kumar M, Visser F, Bose P, Gallo M, Yong VW

Cancer research2023

DOI: 10.1158/0008-5472.can-22-3004 PMID: 37067922

Recurrent 3D genome features in PFA ependymoma

Nominated PICIHR2022Project Grant - Priority Announcement: Pediatric Cancer Research

Principal investigators: Gallo, Marco

Keywords: 3d Genome; Cancer; Ependymoma; Epigenomics; Genomics; Patient-Derived Models; Pediatric Cancer; Pfa; Transcriptomics

$390,000

Canada Reseach Chair - Tier 2

Nominated PICIHR2021Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Gallo, Marco

Keywords: Crc

$500,000

Determining the impact of inosine-producing microbes in promoting the efficacy and modulating toxicity of immune checkpoint blockade therapy in cancer.

Co-investigatorCIHR2021Project Grant

Principal investigators: McCoy, Kathy

Keywords: Anti-Tumor Immunity; Bifidobacteria; Gnotobiotic Mouse Models; Human Microbiome-Associated Mice; Immune Checkpoint Blockade Therapy; Immune-Related Adverse Events; Inosine; Metabolites; Microbiota; Wild Microbiome

$975,376

Dissecting the origins and microenvironment of replication repair deficient hypermutant gliomas for novel immune based therapies

Co-investigatorCIHR2021Project Grant

Principal investigators: Tabori, Uri

Keywords: Brain Tumours; Cancer Genetics; Gliomas; Hypermutation; Immunotherapy

$1,300,500

Mechanisms of epigenetic evolution in pediatric high-grade gliomas

Nominated PICIHR2020Project Grant

Principal investigators: Gallo, Marco

Keywords: Cancer Stem Cells; Childhood Cancer; Chromatin; Epigenetics; Epigenomics; Glioblastoma; Pediatric High-Grade Gliomas; Self-Renewal; Single-Cell Genomics; Transcription Factors

$703,800

Genetic and epigenetic dysregulation caused by transposable elements in pediatric high-grade gliomas.

SupervisorCIHR2019CIHR Fellowship

Principal investigators: Johnston, Michael J

Keywords: Bioinformatics; Brain Development; Dna Damage; Epigenetics; Glioma; Nanopore Sequencing; Pediatric Tumours; Single-Cell Sequencing; Transposable Elements; Whole Genome Sequencing

$90,000

macroH2A shapes self-renewal properties in glioblastoma

Nominated PICIHR2017Project Grant

Principal investigators: Gallo, Marco

Keywords: Brain Tumors; Cancer; Cancer Stem Cells; Chromatin; Epigenetics; Glioblastoma; Histone Variants; Nucleosome; Self-Renewal; Xenografts

$765,000

Determinants of higher order genome architecture

Principal investigatorNSERC2017Discovery Grants Program - Individual

Principal investigators: Gallo, Marco

$217,000

CRC Tier 2

Nominated PICIHR2016Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Gallo, Marco

Keywords: Crc

$500,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Marco Gallo

Research

Latest papers

Latest funding

H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs.

EZHIP boosts neuronal-like synaptic gene programs and depresses polyamine metabolism.

Spatial epigenomic niches underlie glioblastoma cell state plasticity.

CASCADES, a novel SOX2 super-enhancer-associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma.

3D genome topology distinguishes molecular subgroups of medulloblastoma.

TULIPs decorate the three-dimensional genome of PFA ependymoma.

Cancer stem cell hypothesis 2.0 in glioblastoma: Where are we now and where are we going?

Linked-read based analysis of the medulloblastoma genome.

macroH2A2 antagonizes epigenetic programs of stemness in glioblastoma.

Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor-Initiating Cells.

Determinants of higher order genome architecture

Frequent collaborators

Mathieu Lupien

Nada Jabado

Jason Karamchandani

Jason Karamchandani

Jacek Majewski

Mathieu Blanchette

Sunit Das

Sorana Morrissy

Pierre Billon

Robert Vanner

Claudia Kleinman

Mark Bernstein

Darren Brenner

Nada Jabado

Stephen Scherer

Nizar Bahlis

Benjamin Haibe-Kains

Guillaume Bourque

Steven Jones

Kenneth Aldape

Martin Hirst

Samuel Weiss

Uri Tabori

Stephane Angers

David Huntsman

Gelareh Zadeh