Faculty profile

Gilles Gouspillou

ResearcherMedicineMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses and email address may be missing. Find their university profile.

Gilles Gouspillou

Researcher

Medicine

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
23 publications in the last five years, latest in 2026.
Senior (last) author on 9 recent papers, a sign of leading a research group.
Principal investigator on 1 research grant (1 CIHR), most recently in 2024.
Supervised 1 trainee who won CIHR awards, most recently in 2015.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Autophagy Mitochondria Muscle Atrophy Oxidative Stress Peroxisome Reactive Oxygen Species Skeletal Muscle

Latest papers

BCL6 regulates skeletal muscle mass and mitochondrial bioenergetics.
Molecular metabolism · 2026
Skeletal Muscle and Circulating microRNAs Adaptations to 12-Week HIIT With or Without L-Citrulline in Obese Older Adults.
Journal of cachexia, sarcopenia and muscle · 2026
Parkin overexpression attenuates muscle atrophy and improves mitochondrial bioenergetics but not histological features of Duchenne muscular dystrophy in mice.
Scientific reports · 2026 · senior author

All 45 publications

Latest funding

Enhancing the Clinical Benefits of COPD Chronic Management: The SUPplementation with URolithin-A during Pulmonary Rehabilitation in COPD (SUPRA-COPD) Trial
CIHR · 2025 · Co-investigator
$510,087
Regulation of skeletal muscle and peroxisomal homeostasis by Depp1 protein
CIHR · 2024 · Principal investigator
$860,625
MYTHO: An uncharacterized FoxO-dependent gene that controls autophagy and skeletal muscle mass
CIHR · 2020 · Co-investigator
$631,126

All 7 grants and awards

45 publications.

BCL6 regulates skeletal muscle mass and mitochondrial bioenergetics.

Usmani SE, Leduc-Gaudet JP, Chau S, Bellissimo CA, Vohra S, Desjardins K, Pollock-Tahiri E, Shi I, Chun F, Capobianco A, Delisle P, Dupebe W, Cefis M, Marcangeli V, Ghebreselassie M, Liang YC, Seki Y, Mayaki D, Hussain S, Goligher E, Kapoor M, Locke M, Gouspillou G, Woo M

Molecular metabolism2026

DOI: 10.1016/j.molmet.2026.102367 PMID: 41985672

Skeletal Muscle and Circulating microRNAs Adaptations to 12-Week HIIT With or Without L-Citrulline in Obese Older Adults.

Mercier-Guery A, Millet M, Croset M, Marcangeli V, Dulac M, Carvalho LP, Hajj-Boutros G, Gaudreau P, Morais JA, Gouspillou G, Noirez P, Rousseau JC, Chapurlat R, Aubertin-Leheudre M

Journal of cachexia, sarcopenia and muscle2026

DOI: 10.1002/jcsm.70267 PMID: 41933456

Parkin overexpression attenuates muscle atrophy and improves mitochondrial bioenergetics but not histological features of Duchenne muscular dystrophy in mice.

Reynaud O, Ayoub MB, Leduc-Gaudet JP, Cefis M, Lussier MP, Hussain SN, Gouspillou G

Scientific reports2026Senior author

DOI: 10.1038/s41598-025-34223-9 PMID: 41547930

A 12-Week Strength Training Improves Mitochondrial Respiration, H2O2 Emission and Skeletal Muscle Integrity in Women With Myotonic Dystrophy Type 1.

Marcangeli V, Girard-Côté L, Di Leo V, Roussel MP, Lawless C, Charest O, Argaw A, Dulac M, Hajj-Boutros G, Morais JA, Vincent A, Gouspillou G, Leduc-Gaudet JP, Duchesne E

Acta physiologica (Oxford, England)2025

DOI: 10.1111/apha.70135 PMID: 41241935

Canonical and non-canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology.

Chaney R, Marcangeli V, Desjardins K, Taherkhani S, Gouspillou G

The Journal of physiology2025Senior author

DOI: 10.1113/jp287149 PMID: 41273662

EMito-Metrix enables automated evaluation of mitochondrial morphology across species.

Morin E, Doumard E, Hartnell LM, Salegi Ansa B, Leduc-Gaudet JP, Quillien A, Nakhle J, Ethuin S, Goudounèche D, Payré B, Soldan V, Balor S, Mattout A, Rouquette J, Dubois L, Sengenès C, Planat V, Casteilla L, Yart A, Dray C, Aligon J, Ferrucci L, Duchesne É, Hussain SNA, Gouspillou G, Formentini L, Mourier A, Baris OR, Valet P, Parpex H, Monsarrat P, Vigneau M, Pradère JP

Nature metabolism2025

DOI: 10.1038/s42255-025-01400-z PMID: 41094017

Experimental Evidence Against Taurine Deficiency as a Driver of Aging in Humans.

Marcangeli V, Cefis M, Hammad R, Granet J, Leduc-Gaudet JP, Gaudreau P, Aubertin-Leheudre M, Bélanger M, Robitaille R, Morais JA, Gouspillou G

Aging cell2025Senior author

DOI: 10.1111/acel.70191 PMID: 41061678

Exercise attenuates bed rest-induced increases in insulin resistance while α-klotho increases in 55 to 65 year-old women and men.

Mastrandrea CJ, Hajj-Boutros G, Sonjak V, Hedge ET, Gouspillou G, Hughson RL, Morais JA

Scientific reports2025

DOI: 10.1038/s41598-025-12770-5 PMID: 40707556

Impact of physical activity on physical function, mitochondrial energetics, ROS production, and Ca2+ handling across the adult lifespan in men.

Cefis M, Marcangeli V, Hammad R, Granet J, Leduc-Gaudet JP, Gaudreau P, Trumpff C, Huang Q, Picard M, Aubertin-Leheudre M, Bélanger M, Robitaille R, Morais JA, Gouspillou G

Cell reports. Medicine2025Senior author

DOI: 10.1016/j.xcrm.2025.101968 PMID: 39933528

MFN2 overexpression in skeletal muscles of young and old mice causes a mild hypertrophy without altering mitochondrial respiration and H2O2 emission.

Cefis M, Dargegen M, Marcangeli V, Taherkhani S, Dulac M, Leduc-Gaudet JP, Mayaki D, Hussain SNA, Gouspillou G

Acta physiologica (Oxford, England)2024Senior author

DOI: 10.1111/apha.14119 PMID: 38400630

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Gilles Gouspillou

Research

Latest papers

Latest funding

BCL6 regulates skeletal muscle mass and mitochondrial bioenergetics.

Skeletal Muscle and Circulating microRNAs Adaptations to 12-Week HIIT With or Without L-Citrulline in Obese Older Adults.

Parkin overexpression attenuates muscle atrophy and improves mitochondrial bioenergetics but not histological features of Duchenne muscular dystrophy in mice.

A 12-Week Strength Training Improves Mitochondrial Respiration, H2O2 Emission and Skeletal Muscle Integrity in Women With Myotonic Dystrophy Type 1.

Canonical and non-canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology.

EMito-Metrix enables automated evaluation of mitochondrial morphology across species.

Experimental Evidence Against Taurine Deficiency as a Driver of Aging in Humans.

Exercise attenuates bed rest-induced increases in insulin resistance while α-klotho increases in 55 to 65 year-old women and men.

Impact of physical activity on physical function, mitochondrial energetics, ROS production, and Ca2+ handling across the adult lifespan in men.

MFN2 overexpression in skeletal muscles of young and old mice causes a mild hypertrophy without altering mitochondrial respiration and H2O2 emission.

Enhancing the Clinical Benefits of COPD Chronic Management: The SUPplementation with URolithin-A during Pulmonary Rehabilitation in COPD (SUPRA-COPD) Trial

Regulation of skeletal muscle and peroxisomal homeostasis by Depp1 protein

MYTHO: An uncharacterized FoxO-dependent gene that controls autophagy and skeletal muscle mass

Ketone bodies as therapeutic agents to reduce the harmful effects of bed rest on muscle mass and metabolic health in older adults

Regulation of skeletal muscle function by PINK-1-Parkin mitophagy pathway

Unraveling the mechanisms underlying of bed rest-induced muscle atrophy and of an exercise countermeasure

Mechanisms Underlying Sepsis-induced Skeletal Muscle Dysfunction: Role of Autophagy

Frequent collaborators

Gilles Gouspillou

Pierrette Gaudreau

Pierrette Gaudreau

Eli Puterman

Richard Robitaille

Richard Robitaille

Marius Locke

Mohit Kapoor

Hanns Lochmüller

Ewan Goligher

Sabah Hussain

Elise Duchesne

Minna Woo

Guylaine Ferland

Janusz Rak

Yan Burelle

Jean Bourbeau

Gilles Gouspillou

Research

Latest papers

Latest funding

BCL6 regulates skeletal muscle mass and mitochondrial bioenergetics.

Skeletal Muscle and Circulating microRNAs Adaptations to 12-Week HIIT With or Without L-Citrulline in Obese Older Adults.

Parkin overexpression attenuates muscle atrophy and improves mitochondrial bioenergetics but not histological features of Duchenne muscular dystrophy in mice.

A 12-Week Strength Training Improves Mitochondrial Respiration, H2O2 Emission and Skeletal Muscle Integrity in Women With Myotonic Dystrophy Type 1.

Canonical and non-canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology.

EMito-Metrix enables automated evaluation of mitochondrial morphology across species.

Experimental Evidence Against Taurine Deficiency as a Driver of Aging in Humans.

Exercise attenuates bed rest-induced increases in insulin resistance while &#x3b1;-klotho increases in 55 to 65 year-old women and men.

Impact of physical activity on physical function, mitochondrial energetics, ROS production, and Ca2+ handling across the adult lifespan in men.

MFN2 overexpression in skeletal muscles of young and old mice causes a mild hypertrophy without altering mitochondrial respiration and H2O2 emission.

Enhancing the Clinical Benefits of COPD Chronic Management: The SUPplementation with URolithin-A during Pulmonary Rehabilitation in COPD (SUPRA-COPD) Trial

Regulation of skeletal muscle and peroxisomal homeostasis by Depp1 protein

MYTHO: An uncharacterized FoxO-dependent gene that controls autophagy and skeletal muscle mass

Ketone bodies as therapeutic agents to reduce the harmful effects of bed rest on muscle mass and metabolic health in older adults

Regulation of skeletal muscle function by PINK-1-Parkin mitophagy pathway

Unraveling the mechanisms underlying of bed rest-induced muscle atrophy and of an exercise countermeasure

Mechanisms Underlying Sepsis-induced Skeletal Muscle Dysfunction: Role of Autophagy

Frequent collaborators

Gilles Gouspillou

Pierrette Gaudreau

Pierrette Gaudreau

Eli Puterman

Richard Robitaille

Richard Robitaille

Marius Locke

Mohit Kapoor

Hanns Lochmüller

Ewan Goligher

Sabah Hussain

Elise Duchesne

Minna Woo

Guylaine Ferland

Janusz Rak

Yan Burelle

Jean Bourbeau

Exercise attenuates bed rest-induced increases in insulin resistance while α-klotho increases in 55 to 65 year-old women and men.