Faculty profile

Hanns Lochmüller

ResearcherUniversity of Ottawa

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Ottawa directory, so their courses and email address may be missing. Find their university profile.

Hanns Lochmüller

Researcher

Health Sciences

University of Ottawa

Ottawa, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
23 publications in the last five years, latest in 2026.
Senior (last) author on 1 recent paper, a sign of leading a research group.
Principal investigator on 9 research grants (8 CIHR, 1 SSHRC), most recently in 2025.
Supervised 5 trainees who won CIHR awards, most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Neuromuscular Disease Translational Research Crc Networks Genomics Clinical Biomarkers Drug Repurposing Gene Discovery

Latest papers

Strengthening clinical capacity in spinal muscular atrophy: Developing and implementing training on clinical outcome assessments.
Journal of neuromuscular diseases · 2026
Bis(monoacylglycero)phosphate (BMP) as a circulating biomarker of lysosomal dysfunction in GNE myopathy.
Clinica chimica acta; international journal of clinical chemistry · 2026
A toolkit for new facioscapulohumeral muscular dystrophy trial sites.
Journal of neuromuscular diseases · 2026

All 29 publications

Latest funding

Using iPSC-derived neurons to identify novel biomarkers and drug candidates for myotonic dystrophy type 1
CIHR · 2025 · Supervisor
$140,000
Redox signaling via protein S-glutathionylation in muscle stem cell function and muscle repair
CIHR · 2025 · Co-investigator
$1,067,175
Investigating the genetic causes of unsolved neuromuscular disorders
CIHR · 2025 · Supervisor
$120,000

All 15 grants and awards

29 publications.

Strengthening clinical capacity in spinal muscular atrophy: Developing and implementing training on clinical outcome assessments.

Osman H, Masnata M, Adamji Z, Rodrigue X, Nguyen CÉ, Slayter J, Beattie E, Lintern S, Lochmuller H, O'Connell C, Gagnon C, Warman-Chardon J

Journal of neuromuscular diseases2026

DOI: 10.1177/22143602261416298 PMID: 41564276

Bis(monoacylglycero)phosphate (BMP) as a circulating biomarker of lysosomal dysfunction in GNE myopathy.

Manis C, Pertusati F, Morewood J, Roos A, Kleefeld F, Onali M, Pogoryelova O, Derksen A, Spendiff S, Lochmuller H, Videira P, Atzori L, Caboni P

Clinica chimica acta; international journal of clinical chemistry2026

DOI: 10.1016/j.cca.2026.121244 PMID: 42501775

A toolkit for new facioscapulohumeral muscular dystrophy trial sites.

Kools J, Korngut L, Petrillo Ballantyne J, Roozen I, de Haas R, Hill A, Evangelista T, Sansone VA, Roxburgh R, Lochmuller H, Statland J, Johnson NE, Voermans N

Journal of neuromuscular diseases2026

DOI: 10.1177/22143602251399244 PMID: 41451875

Implementation of a neuromuscular clinical trial network: a rare disease model for enhancing clinical trial readiness, capacity, and access in Canada.

Schellenberg KL, Osman H, Masnata M, Hicks R, Kagan C, Stosic A, Lintern S, Beattie E, Lochmuller H, Campbell C, Mah JK

Orphanet journal of rare diseases2026

DOI: 10.1186/s13023-026-04393-4 PMID: 42192450

Novel muscle MRI features in Desmin related myasthenic myopathy.

Baskar D, Tumulu SK, Polavarapu K, Huddar A, Unnikrishnan G, Vengalil S, Nashi S, Nittur V, Arunachal G, Saini J, Lochmuller H, Nalini A

Neuromuscular disorders : NMD2026

DOI: 10.1016/j.nmd.2025.106302 PMID: 41406637

Counting the Cost: The Hidden Financial Realities of Neuromuscular Disease Through Patient and Family Perspectives.

Osman H, Adamji Z, Lintern S, Smith IC, Grant A, Lessard LER, Lochmuller H, McMillan H, Selby K, Pfeffer G, Korngut L, Gagnon C, Thavorn K, Warman-Chardon J

Health expectations : an international journal of public participation in health care and health policy2025

DOI: 10.1111/hex.70529 PMID: 41405177

Financial Toxicity and Its Determinants in Individuals Living With Inherited and Acquired Neuromuscular Disorders: The BIND Study.

Grant A, Smith IC, Lessard LER, Osman H, Lochmuller H, McMillan HJ, Pfeffer G, Korngut L, Gagnon C, Lintern S, Selby KA, Thavorn K, Warman-Chardon J

Neurology2025

DOI: 10.1212/wnl.0000000000213982 PMID: 40834345

Assessing the socio-economic burden of inherited and inflammatory neuromuscular diseases (BIND study): a study protocol.

Smith IC, Abusetah Y, Osman H, Garg A, Grant A, Lochmuller H, McMillan H, Pfeffer G, Korngut L, Gagnon C, Lintern S, Wojtal D, Selby K, Thavorn K, Warman-Chardon J

Orphanet journal of rare diseases2025

DOI: 10.1186/s13023-025-03904-z PMID: 40770363

Pontocerebellar Hypoplasia and Periventricular Leukomalacia Associated With p.Phe262Val Homozygous Variant in TTC1 Gene: A Report of 4 Cases.

Sarıkaya Uzan G, Yaramış AH, Sönmezler E, Hız Kurul S, Yaramış A, Yiş U, Günay Ç, Lochmuller H, Horvath R, Oktay Y, Yaramış A

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience2025

DOI: 10.1002/jdn.70031 PMID: 40879651

Plasma-derived protein and imaging biomarkers distinguish disease severity in oculopharyngeal muscular dystrophy.

Smith IC, Sampaio ML, Melkus G, Meier-Ross K, Chakraborty S, Stotts C, Bourque PR, Lochmuller H, Brais B, Ayoub O, Perkins TJ, Khacho M, Warman-Chardon J

Journal of neuromuscular diseases2025

DOI: 10.1177/22143602241304990 PMID: 39973404

Using iPSC-derived neurons to identify novel biomarkers and drug candidates for myotonic dystrophy type 1

SupervisorCIHR2025Canada Postdoctoral Research Award (CPRA) program

Principal investigators: Geertsma, Haley

Keywords: Alternative Splicing; Myotonic Dystrophy; Neurons; Proteomics; Stem Cells; Transcriptomics

$140,000

Redox signaling via protein S-glutathionylation in muscle stem cell function and muscle repair

Co-investigatorCIHR2025Project Grant

Principal investigators: Khacho, Mireille

Keywords: Glutathione; Mitochondrial Communication; Mitochondrial Function And Metabolism; Muscle Degenerative Diseases; Muscle Function; Muscle Regeneration; Muscle Stem Cells; Muscular Dystrophy; Reactive Oxygen Species

$1,067,175

Investigating the genetic causes of unsolved neuromuscular disorders

SupervisorCIHR2025DRA : Canada Graduate Research Scholarship - Doctoral Program (CGRS D)

Principal investigators: Aksel Kilicarslan, Ozge

Keywords: Bioinformatics; Genetics; Multi-Omics; Neuromuscular Disease; Next-Generation Sequencing

$120,000

Canada Research Chair - Tier 1

Nominated PICIHR2025Canada Research Chairs - CIHR Funded - Tier 1

Principal investigators: Lochmüller, Hanns

Keywords: Crc

$1,400,000

NMD4C: the neuromuscular network for Canada

Nominated PICIHR2023Network Gr. in Skin Health, Bone Health, and Muscular Dyst. - Muscular Dystrophy

Principal investigators: Lochmüller, Hanns; Osman, Homira; Brais, Bernard; Campbell, Craig Gordon N; Chang, Natasha C; Dowling, James; Gagnon, Cynthia; Gonorazky, Hernan D; Hodgkinson, Victoria; Karamchandani, Jason; Korngut, Lawrence W; Kothary, Rashmi K; Mah, Jean K; O'Connell, Colleen; Patten, Kessen; Rossi, Fabio M; Schellenberg, Kerri; Selby, Kathryn A; Warman Chardon, Jodi

Keywords: Clinical Trial Networks; Networks; Neuromuscular Disease; Open Science; Patient Partnerships; Preclinical Research Resources; Training And Education; Translational Research

$1,000,000

Analysis of non-coding regions and novel gene discovery: Exploring the unknown in inherited neuromuscular disorders.

SupervisorCIHR2022CIHR Fellowship

Principal investigators: Polavarapu, Kiran

Keywords: Diagnostics; Gene Discovery; Genetics; Neuromuscular Disease; Non-Coding Regions

$135,000

GNE Myopathy - Determination of disease prevalence and investigations into the importance of sialic acid in muscle differentiation

SupervisorCIHR2022Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Derksen, Alexa R

Keywords: Gne Myopathy; Neuromuscular Disease; Polysialylation; Prevalence; Sialic Acid

$105,000

Accelerating drug repurposing for rare neurological, neurometabolic and neuromuscular diseases by exploiting SIMilarities in clinical and molecular PATHology (SIMPATHIC)

Principal investigatorSSHRC2022New Frontiers in Research Fund - Global Platforms

Principal investigators: Lochmüller, Hanns

Keywords: Neuromuscular Diseases; Drug Repurposing; Clinical Trials; Rare Disease; IPSc; Cellular Models; Drug Screens; Basket Trials

$490,178

BIND Study: Assessing the Indirect Socio-Economic Burden of Inherited Neuromuscular Diseases

Principal investigatorCIHR2021Team Grant: Indirect Socio-Economic Burden of Inherited Diseases

Principal investigators: Warman Chardon, Jodi; Korngut, Lawrence W; Lochmüller, Hanns; Thavorn, Kednapa

Keywords: Indirect Costs

$449,030

Novel therapeutic approaches to target GNE Myopathy

Nominated PICIHR2020Team Grant: E-Rare Joint Transnational Call

Principal investigators: Lochmüller, Hanns

Keywords: Biomarkers; Glycobiology; Gne Myopathy; Innovative Therapeutic Strategies; Multi-Omic; Prodrug; Sialic Acid Pathway

$388,651

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Hanns Lochmüller

Research

Latest papers

Latest funding

Strengthening clinical capacity in spinal muscular atrophy: Developing and implementing training on clinical outcome assessments.

Bis(monoacylglycero)phosphate (BMP) as a circulating biomarker of lysosomal dysfunction in GNE myopathy.

A toolkit for new facioscapulohumeral muscular dystrophy trial sites.

Implementation of a neuromuscular clinical trial network: a rare disease model for enhancing clinical trial readiness, capacity, and access in Canada.

Novel muscle MRI features in Desmin related myasthenic myopathy.

Counting the Cost: The Hidden Financial Realities of Neuromuscular Disease Through Patient and Family Perspectives.

Financial Toxicity and Its Determinants in Individuals Living With Inherited and Acquired Neuromuscular Disorders: The BIND Study.

Assessing the socio-economic burden of inherited and inflammatory neuromuscular diseases (BIND study): a study protocol.

Pontocerebellar Hypoplasia and Periventricular Leukomalacia Associated With p.Phe262Val Homozygous Variant in TTC1 Gene: A Report of 4 Cases.

Plasma-derived protein and imaging biomarkers distinguish disease severity in oculopharyngeal muscular dystrophy.

Accelerating drug repurposing for rare neurological, neurometabolic and neuromuscular diseases by exploiting SIMilarities in clinical and molecular PATHology (SIMPATHIC)

Frequent collaborators

Jodi Warman Chardon

Homira Osman

Kednapa Thavorn

Lawrence Korngut

Kednapa Thavorn

Cynthia Gagnon

Gerald Pfeffer

Gilles Gouspillou

Nancy Maltez

Gerd Melkus

Craig Campbell

Cynthia Gagnon

Homira Osman

Craig Campbell

Bernard Brais

Mireille Khacho