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Research
Latest papers
A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss.
PLoS pathogens · 2026
Mitochondria-lysosome-related organelles mediate mitochondrial clearance during cellular dedifferentiation.
Cell reports · 2023
Latest funding
- $140,000
Mechanisms and regulation of peroxisome biogenesis
CIHR · 2025 · Supervisor
- $1,289,025
Mitochondrial directed SUMOylation in the regulation of cell survival and immunity in cancer
CIHR · 2025 · Nominated PI
- $967,725
Uncovering the mechanisms and meaning of Mitochondrial Derived Vesicles
CIHR · 2022 · Nominated PI
2 publications.
A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss.
Mukherjee S, Grouza V, Tchung A, Even A, Yaqubi M, Tuznik M, Cannon T, Recinto SJ, Gavino C, Bourque MJ, Giguère N, McBride H, Desjardins M, Gruenheid S, Stratton JA, Rudko DA, Trudeau LE
Mitochondria-lysosome-related organelles mediate mitochondrial clearance during cellular dedifferentiation.
Ma X, Manley S, Qian H, Li Y, Zhang C, Li K, Ding B, Guo F, Chen A, Zhang X, Liu M, Hao M, Kugler B, Morris EM, Thyfault J, Yang L, Sesaki H, Ni HM, McBride H, Ding WX
Mechanisms and regulation of peroxisome biogenesis
Principal investigators: Ilacqua, Nicolo
Keywords: De Novo Biogenesis; Endomembrane Trafficking; Microscopy; Mitochondria; Mitochondrial-Derived Vesicles (Mdvs); Organelles; Peroxisomes; Zellweger Syndrome
Mitochondrial directed SUMOylation in the regulation of cell survival and immunity in cancer
Principal investigators: McBride, Heidi M
Keywords: Cancer; Dna Damage; Immunity; Mitochondrial Derived Vesicles; Mitochondrial Signalling; Mtdna Release; Pyroptosis; Sumoylation
Uncovering the mechanisms and meaning of Mitochondrial Derived Vesicles
Principal investigators: McBride, Heidi M
Keywords: Gtpases; Inflammation; Lipid Modification; Lysosome; Miro1; Mitochondria; Neurodegeneration; Quality Control; Reconstitution; Vesicle Transport
Investigation of the function of de novo peroxisomal biogenesis
Principal investigators: Besse-Patin, Aurèle
Keywords: Biogenesis; Genetics; Mitochondria; Peroxisome; Zellweger
Investigating the mechanisms of iron delivery to mitochondria.
Principal investigators: McBride, Heidi M
Keywords: Endosome; Ferroptosis; Friedreich'S Ataxia; Iron Disease; Iron Transport; Mitochondria; Rab5
Canada Research Chair Tier 1
Principal investigators: McBride, Heidi M
Keywords: Crc
Mechanism and function of mitochondrial derived vesicle transport to peroxisomes.
Principal investigators: McBride, Heidi M
Keywords: Mapl; Mitochondrial Derived Vesicles; Parkinson'S Disease; Peroxisome Biogenesis; Pex16; Pex3; Rare Disease; Redox Signaling; Vps35; Zellwegers Syndrome
The role of SUMOylation in mitochondrial dynamics and physiology.
Principal investigators: McBride, Heidi M
Keywords: Apoptosis; Calcium; Cancer; Drp1; Fission; Interorganellar Contacts; Metabolic Flux; Mitochondrial Dynamics; Sumo; Sumo E3 Ligase
Mitochondrial contribution to innate immune pathways
Principal investigators: McBride, Heidi M; Gross, Atan
Keywords: Bid; Dynamics; Innate Immunity; Inter-Organellar Contacts; Mavs; Metabolism; Mitochondria; Signaling
Involvement of the Endoplasmic reticulum-mitochondria contact sites in Bax-induced apoptosis: Fundamental role of the mitochondrial SUMOylation
Principal investigators: Prudent, Julien
Keywords: Apoptosis; Biochemistry; Calcium Signaling; Cancer; Cell Biology; Confocal Microscopy Analysis; Lipid Signaling; Mitochondrial Dynamics; Mitochondrial Sumoylation; Molecular Biology
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Neurology and Neurosurgery
- Pharmacology
- Pathology & Cell Biology
- Microbiology and Immunology
Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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