Faculty profile

Michel Desjardins

ResearcherPathology & Cell BiologyUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.

Michel Desjardins

Researcher

Pathology & Cell Biology

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
5 publications in the last five years, latest in 2026.
Senior (last) author on 1 recent paper, a sign of leading a research group.
Principal investigator on 4 research grants (4 CIHR), most recently in 2019.
Supervisor on 1 trainee award (1 CIHR), most recently in 2010.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Animal Model Autoimmune Disease Cell Biology Parkinson'S Disease Adaptive Immunity Autophagy Immunology Proteomics

Latest papers

An LRRK2 variant blocks NCOA4 trafficking upon iron overload, leading to ferroptotic death.
Journal of cell science · 2026
A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss.
PLoS pathogens · 2026
STING dampens the unfolded protein response to enable the presentation of self-antigens on MHC-I during inflammation.
Cell reports · 2026 · senior author

All 16 publications

Latest funding

Inflammation and autoimmunity as triggers of axonal dying-back in PD
CIHR · 2019 · Co-investigator
$948,600
The role of Parkinson's disease-related proteins in innate and adaptive immunity
CIHR · 2019 · Nominated PI
$883,575
Molecular characterization of the contribution of autophagy to antigen presentation using an iterative proteomics approach
CIHR · 2013 · Nominated PI
$846,703

All 6 grants and awards

16 publications.

An LRRK2 variant blocks NCOA4 trafficking upon iron overload, leading to ferroptotic death.

Goldman A, Nguyen M, Lanoix J, Li C, Fahmy A, Xu YZ, Schurr E, Thibault P, Desjardins M, McBride HM

Journal of cell science2026

DOI: 10.1242/jcs.264977 PMID: 42206576

A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss.

Mukherjee S, Grouza V, Tchung A, Even A, Yaqubi M, Tuznik M, Cannon T, Recinto SJ, Gavino C, Bourque MJ, Giguère N, McBride H, Desjardins M, Gruenheid S, Stratton JA, Rudko DA, Trudeau LE

PLoS pathogens2026

DOI: 10.1371/journal.ppat.1014315 PMID: 42378309

STING dampens the unfolded protein response to enable the presentation of self-antigens on MHC-I during inflammation.

Fahmy AM, Ahmadi A, Lanoix J, Cannon T, Elemeery MN, Paredes CH, Barrette B, Bonneil E, Xu YZ, Ibrahim M, Arango-Duque G, Audemard EO, Lemieux S, Chevet E, Schurr E, Pierre P, Gruenheid S, Thibault P, McBride HM, Desjardins M

Cell reports2026Senior author

DOI: 10.1016/j.celrep.2026.117497 PMID: 42275211

Author Correction: Lrrk2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis.

Pei J, Oliveira NL, Recinto SJ, Kazanova A, Queiroz-Junior CM, Li Z, Couto K, Westfall S, Fahmy AM, Tiefensee-Ribeiro C, King IL, Milnerwood AJ, Desjardins M, Thanabalasuriar A, Stratton JA, Gruenheid S

NPJ Parkinson's disease2026

DOI: 10.1038/s41531-026-01285-z PMID: 41826345

Lrrk2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis.

NPJ Parkinson's disease2025

DOI: 10.1038/s41531-025-01077-x PMID: 40883285

Intestinal infection triggers Parkinson's disease-like symptoms in Pink1-/- mice.

Matheoud D, Cannon T, Voisin A, Penttinen AM, Ramet L, Fahmy AM, Ducrot C, Laplante A, Bourque MJ, Zhu L, Cayrol R, Le Campion A, McBride HM, Gruenheid S, Trudeau LE, Desjardins M

Nature2019Senior author

DOI: 10.1038/s41586-019-1405-y PMID: 31316206

Parkinson's Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation.

Matheoud D, Sugiura A, Bellemare-Pelletier A, Laplante A, Rondeau C, Chemali M, Fazel A, Bergeron JJ, Trudeau LE, Burelle Y, Gagnon E, McBride HM, Desjardins M

Cell2016Senior author

DOI: 10.1016/j.cell.2016.05.039 PMID: 27345367

Alternative pathways for MHC class I presentation: a new function for autophagy.

Chemali M, Radtke K, Desjardins M, English L

Cellular and molecular life sciences : CMLS2011

DOI: 10.1007/s00018-011-0660-3 PMID: 21390546

Cell biology through proteomics--ad astra per alia porci.

Bergeron JJ, Au CE, Desjardins M, McPherson PS, Nilsson T

Trends in cell biology2010

DOI: 10.1016/j.tcb.2010.02.005 PMID: 20227883

Nuclear membrane-derived autophagy, a novel process that participates in the presentation of endogenous viral antigens during HSV-1 infection.

English L, Chemali M, Desjardins M

Autophagy2009Senior author

DOI: 10.4161/auto.5.7.9163 PMID: 19556870

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Michel Desjardins

Research

Latest papers

Latest funding

An LRRK2 variant blocks NCOA4 trafficking upon iron overload, leading to ferroptotic death.

A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss.

STING dampens the unfolded protein response to enable the presentation of self-antigens on MHC-I during inflammation.

Author Correction: Lrrk2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis.

Lrrk2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis.

Intestinal infection triggers Parkinson's disease-like symptoms in Pink1-/- mice.

Parkinson's Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation.

Alternative pathways for MHC class I presentation: a new function for autophagy.

Cell biology through proteomics--ad astra per alia porci.

Nuclear membrane-derived autophagy, a novel process that participates in the presentation of endogenous viral antigens during HSV-1 infection.

Inflammation and autoimmunity as triggers of axonal dying-back in PD

The role of Parkinson's disease-related proteins in innate and adaptive immunity

Molecular characterization of the contribution of autophagy to antigen presentation using an iterative proteomics approach

Molecular and cellular characterization of phagosome and autophagosome biogenesis and their role in antigen presentation

Implication du réticulum endoplasmique dans les propriétés de la présentation croisée du phagosome

CANADA RESEARCH CHAIRHOLDER / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA

Frequent collaborators

Samantha Gruenheid

Louis-Eric Trudeau

Erwin Schurr

Ajitha Thanabalasuriar

Etienne Gagnon

Pierre Thibault

Heidi McBride