Jackie Vogel, McGill University

Research

Microtubules +Tip Proteins Cell Division Cell Polarity Membrane-Less Organelles Myosin Spindle Positioning Biophysics

Latest papers

Protein UFMylation regulates early events during ribosomal DNA-damage response.
Cell reports · 2024
Contact sites between endoplasmic reticulum sheets and mitochondria regulate mitochondrial DNA replication and segregation.
iScience · 2023
Kar9 symmetry breaking alone is insufficient to ensure spindle alignment.
Scientific reports · 2021 · senior author

All 22 publications

Latest funding

Investigation of the +TIP body, a microtubule-associated fluid droplet that positions the spindle in polarized cells
CIHR · 2025 · Nominated PI
$1,013,626
The Centrosome as a Compass for Asymmetric Cells
NSERC · 2020 · Principal investigator
$216,000
Investigating the role of gamma-tubulin in spindle stability and function
CIHR · 2019 · Nominated PI
$638,776

All 15 grants and awards

22 publications.

01

Protein UFMylation regulates early events during ribosomal DNA-damage response.

Panichnantakul P, Aguilar LC, Daynard E, Guest M, Peters C, Vogel J, Oeffinger M

Cell reports2024

DOI: 10.1016/j.celrep.2024.114738 PMID: 39277864

02

Contact sites between endoplasmic reticulum sheets and mitochondria regulate mitochondrial DNA replication and segregation.

Ilamathi HS, Benhammouda S, Lounas A, Al-Naemi K, Desrochers-Goyette J, Lines MA, Richard FJ, Vogel J, Germain M

iScience2023

DOI: 10.1016/j.isci.2023.107180 PMID: 37534187

03

Kar9 symmetry breaking alone is insufficient to ensure spindle alignment.

Meziane M, Genthial R, Vogel J

Scientific reports2021Senior author

DOI: 10.1038/s41598-021-83136-w PMID: 33608583

04

Successive Kinesin-5 Microtubule Crosslinking and Sliding Promote Fast, Irreversible Formation of a Stereotyped Bipolar Spindle.

Leary A, Sim S, Nazarova E, Shulist K, Genthial R, Yang SK, Bui KH, Francois P, Vogel J

Current biology : CB2019Senior author

DOI: 10.1016/j.cub.2019.09.030 PMID: 31679937

05

Side chain electrostatic interactions and pH-dependent expansion of the intrinsically disordered, highly acidic carboxyl-terminus of γ-tubulin.

Payliss BJ, Vogel J, Mittermaier AK

Protein science : a publication of the Protein Society2019

DOI: 10.1002/pro.3618 PMID: 30968464

06

Interphase Microtubules Safeguard Mitotic Progression by Suppressing an Aurora B-Dependent Arrest Induced by DNA Replication Stress.

Laflamme G, Sim S, Leary A, Pascariu M, Vogel J, D'Amours D

Cell reports2019

DOI: 10.1016/j.celrep.2019.02.051 PMID: 30865880

07

Author Correction: Interrogation of γ-tubulin alleles using high-resolution fitness measurements reveals a distinct cytoplasmic function in spindle alignment.

Shulist K, Yen E, Kaitna S, Leary A, Decterov A, Gupta D, Vogel J

Scientific reports2018Senior author

DOI: 10.1038/s41598-018-19512-w PMID: 29391486

08

Concerted millisecond timescale dynamics in the intrinsically disordered carboxyl terminus of γ-tubulin induced by mutation of a conserved tyrosine residue.

Harris J, Shadrina M, Oliver C, Vogel J, Mittermaier A

Protein science : a publication of the Protein Society2018

DOI: 10.1002/pro.3345 PMID: 29127738

09

Spatial cues and not spindle pole maturation drive the asymmetry of astral microtubules between new and preexisting spindle poles.

Lengefeld J, Yen E, Chen X, Leary A, Vogel J, Barral Y

Molecular biology of the cell2018

DOI: 10.1091/mbc.e16-10-0725 PMID: 29142076

10

Interrogation of γ-tubulin alleles using high-resolution fitness measurements reveals a distinct cytoplasmic function in spindle alignment.

Shulist K, Yen E, Kaitna S, Leary A, Decterov A, Gupta D, Vogel J

Scientific reports2017Senior author

DOI: 10.1038/s41598-017-11789-7 PMID: 28900268

Investigation of the +TIP body, a microtubule-associated fluid droplet that positions the spindle in polarized cells

Nominated PICIHR2025Project Grant

Principal investigators: Vogel, Jackie

Keywords: +Tip Proteins; Cell Division; Cell Polarity; Membrane-Less Organelles; Microtubules; Myosin; Spindle Positioning

$1,013,626

The Centrosome as a Compass for Asymmetric Cells

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Vogel, Jackie

$216,000

Investigating the role of gamma-tubulin in spindle stability and function

Nominated PICIHR2019Project Grant

Principal investigators: Vogel, Jackie

Keywords: Biophysics; Cell Biology; Cell Cycle; Chromosomes; Gamma-Tubulin; Microtubules; Mitosis; Mitotic Spindle; Phosphorylation; Proteins

$638,776

Bioengineering Facility for Confocal Rheology

Co-investigatorNSERC2015Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Ehrlicher, Allen

$150,000

Collaborative development of software for multi-modal segmentation of biological data

Principal investigatorNSERC2014Engage Grants Program

Principal investigators: Vogel, Jackie

$20,346

The role of symmetry and symmetry breaking in mitosis

Principal investigatorNSERC2013Discovery Grants Program - Individual

Principal investigators: Vogel, Jackie

$215,000

New tools for quantitative measurements of super-resolution image data

Principal investigatorNSERC2013Engage Grants Program

Principal investigators: Vogel, Jackie

$21,500

Coordination of Spindle Assembly and Function by the g-Tubulin Complex

Nominated PICIHR2012Operating Grant

Principal investigators: Vogel, Jackie

Keywords: Automated Tracking And Feature Finding; Cell Biology And Molecular Genetics; Cell Divison; Computational Biology; Cytoskeleton; Experimental Biophysics; Genomics; Intracellular Signaling; Microscopy And Image Analysis; Proteomics

$625,814

Analysis of dynamic systems in cells using simultaneous 2-channel imaging

Principal investigatorNSERC2011Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Vogel, Jackie

$72,771

NSERC CREATE Training Program in Cellular dynamics of macromolelecular complexes

Co-investigatorNSERC2010Collaborative Research and Training Experience

Principal investigators: Baron, Christian

$1,600,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Biology
Biochimie et médecine moléculaire
Chemistry
Cellular and Molecular Medicine
Biomedical Engineering
Computer Science

Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Paul François

Biochimie et médecine moléculaire

2 shared papers, latest 2019

David Juncker

Biomedical Engineering

1 shared papers, latest 2010

Jerome Waldispuhl

Computer Science

1 shared papers, latest 2014

Damien D'Amours

Cellular and Molecular Medicine

1 shared papers, latest 2019

Anthony Mittermaier

Chemistry

1 shared papers, latest 2018

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Microtubules Dear Professor Vogel, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Protein UFMylation regulates early events during ribosomal DNA-damage response." (2024), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Investigation of the +TIP body, a microtubule-associated fluid droplet that positions the spindle in polarized cells" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Jackie Vogel

Research

Latest papers

Latest funding

Protein UFMylation regulates early events during ribosomal DNA-damage response.

Contact sites between endoplasmic reticulum sheets and mitochondria regulate mitochondrial DNA replication and segregation.

Kar9 symmetry breaking alone is insufficient to ensure spindle alignment.

Successive Kinesin-5 Microtubule Crosslinking and Sliding Promote Fast, Irreversible Formation of a Stereotyped Bipolar Spindle.

Side chain electrostatic interactions and pH-dependent expansion of the intrinsically disordered, highly acidic carboxyl-terminus of &#x3b3;-tubulin.

Interphase Microtubules Safeguard Mitotic Progression by Suppressing an Aurora B-Dependent Arrest Induced by DNA Replication Stress.

Author Correction: Interrogation of &#x3b3;-tubulin alleles using high-resolution fitness measurements reveals a distinct cytoplasmic function in spindle alignment.

Concerted millisecond timescale dynamics in the intrinsically disordered carboxyl terminus of &#x3b3;-tubulin induced by mutation of a conserved tyrosine residue.

Spatial cues and not spindle pole maturation drive the asymmetry of astral microtubules between new and preexisting spindle poles.

Interrogation of &#x3b3;-tubulin alleles using high-resolution fitness measurements reveals a distinct cytoplasmic function in spindle alignment.

Investigation of the +TIP body, a microtubule-associated fluid droplet that positions the spindle in polarized cells

The Centrosome as a Compass for Asymmetric Cells

Investigating the role of gamma-tubulin in spindle stability and function

Bioengineering Facility for Confocal Rheology

Collaborative development of software for multi-modal segmentation of biological data

The role of symmetry and symmetry breaking in mitosis

New tools for quantitative measurements of super-resolution image data

Coordination of Spindle Assembly and Function by the g-Tubulin Complex

Analysis of dynamic systems in cells using simultaneous 2-channel imaging

NSERC CREATE Training Program in Cellular dynamics of macromolelecular complexes

Frequent collaborators

Paul François

David Juncker

Jerome Waldispuhl

Damien D'Amours

Anthony Mittermaier

Side chain electrostatic interactions and pH-dependent expansion of the intrinsically disordered, highly acidic carboxyl-terminus of γ-tubulin.

Author Correction: Interrogation of γ-tubulin alleles using high-resolution fitness measurements reveals a distinct cytoplasmic function in spindle alignment.

Concerted millisecond timescale dynamics in the intrinsically disordered carboxyl terminus of γ-tubulin induced by mutation of a conserved tyrosine residue.

Interrogation of γ-tubulin alleles using high-resolution fitness measurements reveals a distinct cytoplasmic function in spindle alignment.