Jianyu Li, McGill University

Research

Biomaterials Regenerative Medicine Crc Biomechanics Bioadhesives Intervertebral Disc Stem Cells Tissue Repair

Latest papers

Computational screening of alginate biomaterials for intervertebral disc repair via agent-based simulation.
Computer methods and programs in biomedicine · 2026
Biomimetic Hydrogels with Nucleus Pulposus-like Viscoelasticity and ECM Peptides for Discogenic Differentiation of Stem Cells.
ACS biomaterials science & engineering · 2026 · senior author
Bacteria-mimetic bioadhesives with multivalent mucoadhesion and drug-compatible delivery.
Materials horizons · 2026 · senior author

All 43 publications

Latest funding

Mechanotransductive Regenerative Bioadhesives for Intervertebral Disc Repair and Regeneration
CIHR · 2025 · Nominated PI
$791,776
Advancing physical intelligence of bioadhesives
NSERC · 2024 · Principal investigator
$46,000
Canada Research Chair - Tier 2
CIHR · 2024 · Nominated PI
$500,000

All 16 grants and awards

43 publications.

01

Computational screening of alginate biomaterials for intervertebral disc repair via agent-based simulation.

Munipalle M, Bonomo R, Dang A, Liu Y, Li X, Li J, Li-Jessen NYK

Computer methods and programs in biomedicine2026

DOI: 10.1016/j.cmpb.2026.109646 PMID: 42759153

02

Biomimetic Hydrogels with Nucleus Pulposus-like Viscoelasticity and ECM Peptides for Discogenic Differentiation of Stem Cells.

Liu Y, Cheng Y, Johnston E, Jiang S, Cherif H, Juncker D, Li-Jessen NYK, Haglund L, Li J

ACS biomaterials science & engineering2026Senior author

DOI: 10.1021/acsbiomaterials.5c02074 PMID: 42695568

03

Bacteria-mimetic bioadhesives with multivalent mucoadhesion and drug-compatible delivery.

Johnston E, Farrow M, Williston R, Wu J, Yang Z, Bahmani A, Liu Y, Huang X, Guo S, Yan J, Li J

Materials horizons2026Senior author

DOI: 10.1039/d6mh00245e PMID: 42430245

04

Click-crosslinked nanogels integrated into 3D stem cell spheroids enhance regenerative function for swallowing muscle repair.

Okuyama H, Brown M, Munipalle M, Nejati S, Huo R, Sakata H, Mizuta R, Sasaki Y, Akiyoshi K, Ohnishi H, Kishimoto Y, Omori K, Li J, Mongeau L, Li-Jessen NYK

Biomaterials2026

DOI: 10.1016/j.biomaterials.2026.124044 PMID: 41650592

05

Computational Advances in Biomaterial Engineering: Mapping Research Trajectories Through Bibliometric Analysis.

Munipalle M, Dang A, Celiz A, Li J, Li-Jessen NYK

Tissue engineering. Part B, Reviews2026

DOI: 10.1177/19373368261449957 PMID: 42175949

06

Engineering tough blood clots for rapid haemostasis and enhanced regeneration.

Jiang S, Bao G, Yang Z, Wu J, Yang X, Kim JEJ, Jiang R, Zhan Y, Nottegar A, Liu Y, Gao ZH, Beckett A, Nijnik A, Long R, Kastrup C, Li J

Nature2026Senior author

DOI: 10.1038/s41586-026-10412-y PMID: 42056507

07

Agitation-Driven Fusion Fabrication of Macroscopic Cell-Laden Cryogels.

Bahmani A, Johnston E, Wan W, Li X, Bao G, Li J

ACS applied bio materials2026Senior author

DOI: 10.1021/acsabm.5c02235 PMID: 41703766

08

Clicktetrazine dECM-alginate hydrogels for injectable, mechanically mimetic, and biologically active vocal fold biomaterials.

Brown M, Okuyama H, Li L, Yang Z, Li J, Tabrizian M, Li-Jessen NYK

Biomaterials2026

DOI: 10.1016/j.biomaterials.2025.123590 PMID: 40784130

09

Advanced polyelectrolyte complexes for ultrafast hemostasis and blood superabsorption.

Fanaee S, Zabihihesari A, Ning T, Austin W, Wolverton M, Leung BM, Bearne SL, Li J, Filiaggi MJ, Adibnia V

Acta biomaterialia2026

DOI: 10.1016/j.actbio.2025.11.021 PMID: 41241116

10

3D necroprinting: Leveraging biotic material as the nozzle for 3D printing.

Puma J, Yang Z, Johnston E, Zhang Z, Lan X, Zhang L, Hou H, He Z, Afify A, Creighton MA, Li J, Cao C

Science advances2025

DOI: 10.1126/sciadv.adw9953 PMID: 41259509

Mechanotransductive Regenerative Bioadhesives for Intervertebral Disc Repair and Regeneration

Nominated PICIHR2025Project Grant

Principal investigators: Li, Jianyu

Keywords: Bioadhesives; Biomaterials; Intervertebral Disc; Regenerative Medicine; Stem Cells; Tissue Repair

$791,776

Advancing physical intelligence of bioadhesives

Principal investigatorNSERC2024Discovery Grants Program - Individual

Principal investigators: Li, Jianyu

Keywords: bioadhesives; hydrogels; adhesion; solid mechanics; soft materials

$46,000

Canada Research Chair - Tier 2

Nominated PICIHR2024Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Li, Jianyu

Keywords: Crc

$500,000

Sono-Fabrication: A Multimodal Ultrasound Approach to Fabricate Hydrogels

Principal investigatorNSERC2023Alliance Grants

Principal investigators: Li, Jianyu J

Keywords: 3D printing; Advanced manufacture; Hydrogels; Soft Materials; Ultrasound

$90,000

Living bacteria bioadhesives for chronic and infected wound care

Principal investigatorSSHRC2022New Frontiers in Research Fund - Exploration

Principal investigators: Li, Jianyu

Keywords: bioadhesives ; chronic wounds; antibacterial materials; engineered living materials ; biofilm

$125,000

Living bacteria bioadhesives for chronic and infected wound care

Principal investigatorSSHRC2022New Frontiers in Research Fund - Exploration

Principal investigators: Li, Jianyu

Keywords: bioadhesives chronic wounds antibacterial materials engineered living materials biofilm

$125,000

Bioengineering Tough Blood Clots for Hemorrhage Control

Nominated PICIHR2021Project Grant

Principal investigators: Li, Jianyu

Keywords: Biomaterials; Biomechanics; Bleeding Disorders; Cellular Engineering; Click Chemistry; Hemorrage; Hemostasis

$677,025

Design and validation of hemostatic surgical sutures_x000d_ _x000d_

Principal investigatorNSERC2020Alliance Grants

Principal investigators: Li, Jianyu

$30,000

Mechanically and Biologically Functional Adhesives for Intervertebral Disc Repair and Regeneration

Nominated PICIHR2019Project Grant

Principal investigators: Li, Jianyu

Keywords: Biomaterials; Biomechanics; Biomedical Adhesives; Intervertebral Disc Repair; Regenerative Medicine; Tissue Engineering

$520,200

Canada-UK AI 2019 : AI-driven biomaterial screening to accelerate medical device development and translation

Co-investigatorNSERC2019Alliance Grants

Principal investigators: LiJessen, NicoleYeeKey

$519,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Biomedical Engineering
Oncology
Mechanical Engineering
Rheumatology and Orthopaedic Surgery
Michael Smith Laboratories
Orthopédie
Physiology
Other

Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Lisbet Haglund

Rheumatology and Orthopaedic Surgery

6 shared papers, latest 2026

Maryam Tabrizian

Biomedical Engineering

3 shared papers, latest 2026

Guojun Chen

Biomedical Engineering

2 shared papers, latest 2025

Christian Kastrup

Michael Smith Laboratories

2 shared papers, latest 2026

David Juncker

Biomedical Engineering

2 shared papers, latest 2026

Jeremy Brown

Biomedical Engineering

1 shared papers, latest 2025

Nader Sadeghi

Otolaryngology

1 shared papers, latest 2022

Christopher Moraes

Chemical Engineering

1 shared papers, latest 2022

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Biomaterials Dear Professor Li, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Computational screening of alginate biomaterials for intervertebral disc repair via agent-based simulation." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Mechanotransductive Regenerative Bioadhesives for Intervertebral Disc Repair and Regeneration" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Jianyu Li

Research

Latest papers

Latest funding

Computational screening of alginate biomaterials for intervertebral disc repair via agent-based simulation.

Biomimetic Hydrogels with Nucleus Pulposus-like Viscoelasticity and ECM Peptides for Discogenic Differentiation of Stem Cells.

Bacteria-mimetic bioadhesives with multivalent mucoadhesion and drug-compatible delivery.

Click-crosslinked nanogels integrated into 3D stem cell spheroids enhance regenerative function for swallowing muscle repair.

Computational Advances in Biomaterial Engineering: Mapping Research Trajectories Through Bibliometric Analysis.

Engineering tough blood clots for rapid haemostasis and enhanced regeneration.

Agitation-Driven Fusion Fabrication of Macroscopic Cell-Laden Cryogels.

Clicktetrazine dECM-alginate hydrogels for injectable, mechanically mimetic, and biologically active vocal fold biomaterials.

Advanced polyelectrolyte complexes for ultrafast hemostasis and blood superabsorption.

3D necroprinting: Leveraging biotic material as the nozzle for 3D printing.

Mechanotransductive Regenerative Bioadhesives for Intervertebral Disc Repair and Regeneration

Advancing physical intelligence of bioadhesives

Canada Research Chair - Tier 2

Sono-Fabrication: A Multimodal Ultrasound Approach to Fabricate Hydrogels

Living bacteria bioadhesives for chronic and infected wound care

Living bacteria bioadhesives for chronic and infected wound care

Bioengineering Tough Blood Clots for Hemorrhage Control

Design and validation of hemostatic surgical sutures_x000d_ _x000d_

Mechanically and Biologically Functional Adhesives for Intervertebral Disc Repair and Regeneration

Canada-UK AI 2019 : AI-driven biomaterial screening to accelerate medical device development and translation

Frequent collaborators

Lisbet Haglund

Maryam Tabrizian

Guojun Chen

Marie-Lyne Nault

Christian Kastrup

David Juncker

Jean Provost

Jeremy Brown

Vahid Adibnia

Morag Park

Nader Sadeghi

Anastasia Nijnik

Morag Park

Christopher Moraes