Faculty profile

Pierre Moffatt

ResearcherHuman GeneticsMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Pierre Moffatt

Researcher

Human Genetics

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
6 publications in the last five years, latest in 2026.
Senior (last) author on 1 recent paper, a sign of leading a research group.
Principal investigator on 4 research grants (4 CIHR), most recently in 2020.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

Search on Google Scholar

Find them onX · LinkedIn · Bluesky · YouTube

Signals and details

Research

Osteogenesis Imperfecta Bone Physiology/Pathology Cell Biology Cell Culture Micro Computed Tomography Molecular Biology Pcr Transgenic/Knockin Mouse Models

Latest papers

Two Novel ACTC1 Variants Cause Arthrogryposis Multiplex Congenita.
Clinical genetics · 2026
Characterisation of Urine-Derived Cells for the Molecular Diagnosis of Rare Disorders.
International journal of molecular sciences · 2026
Tall Stature and Scoliosis Associated With a Novel Homozygous Loss-of-Function Missense Variant in NPR3.
American journal of medical genetics. Part A · 2025 · first author

All 37 publications

Latest funding

A precision medicine approach for treatment of low bone mass in Klinefelter Syndrome
CIHR · 2025 · Co-investigator
$990,675
The Role of BRIL in the Pathogenesis of Osteogenesis Imperfecta.
CIHR · 2020 · Nominated PI
$669,375
The role of BRIL in the pathogenesis of osteogenesis imperfecta type V.
CIHR · 2014 · Nominated PI
$549,170

All 9 grants and awards

37 publications.

Two Novel ACTC1 Variants Cause Arthrogryposis Multiplex Congenita.

Kerr L, Moffatt P, Hyer L, Nossov S, Dahan-Oliel N, Rauch F

Clinical genetics2026

DOI: 10.1111/cge.70218 PMID: 42458772

Characterisation of Urine-Derived Cells for the Molecular Diagnosis of Rare Disorders.

Ludwig K, Wu Z, Bardai G, Marulanda J, Munns CF, Moffatt P, Rauch F

International journal of molecular sciences2026

DOI: 10.3390/ijms27072929 PMID: 41977117

Tall Stature and Scoliosis Associated With a Novel Homozygous Loss-of-Function Missense Variant in NPR3.

Moffatt P, Janelle C, Miranda V, Bardai G, Rauch F

American journal of medical genetics. Part A2025First author

DOI: 10.1002/ajmg.a.64080 PMID: 40171685

RNA Sequencing of Urine-Derived Cells for the Characterization and Diagnosis of Osteogenesis Imperfecta.

Ludwig K, Wu Z, Bardai G, Mason P, Ward LM, Moffatt P, Rauch F

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2023

DOI: 10.1002/jbmr.4865 PMID: 37293821

Dominant osteogenesis imperfecta with low bone turnover caused by a heterozygous SP7 variant.

Ludwig K, Ward LM, Khan N, Robinson ME, Miranda V, Bardai G, Moffatt P, Rauch F

Bone2022

DOI: 10.1016/j.bone.2022.116400 PMID: 35367406

The Osteogenesis Imperfecta Type V Mutant BRIL/IFITM5 Promotes Transcriptional Activation of MEF2, NFATc, and NR4A in Osteoblasts.

Maranda V, Gaumond MH, Moffatt P

International journal of molecular sciences2022Senior author

DOI: 10.3390/ijms23042148 PMID: 35216266

Effect of human secretory calcium-binding phosphoprotein proline-glutamine rich 1 protein on Porphyromonas gingivalis and identification of its active portions.

Mary C, Fouillen A, Moffatt P, Guadarrama Bello D, Wazen RM, Grenier D, Nanci A

Scientific reports2021

DOI: 10.1038/s41598-021-02661-w PMID: 34887426

Muscle transcriptome in mouse models of osteogenesis imperfecta.

Moffatt P, Boraschi-Diaz I, Bardai G, Rauch F

Bone2021First author

DOI: 10.1016/j.bone.2021.115940 PMID: 33812081

Calvaria Bone Transcriptome in Mouse Models of Osteogenesis Imperfecta.

Moffatt P, Boraschi-Diaz I, Marulanda J, Bardai G, Rauch F

International journal of molecular sciences2021First author

DOI: 10.3390/ijms22105290 PMID: 34069814

A proline rich protein from the gingival seal around teeth exhibits antimicrobial properties against Porphyromonas gingivalis.

Fouillen A, Mary C, Ponce KJ, Moffatt P, Nanci A

Scientific reports2021

DOI: 10.1038/s41598-021-81791-7 PMID: 33504866

A precision medicine approach for treatment of low bone mass in Klinefelter Syndrome

Co-investigatorCIHR2025Project Grant

Principal investigators: St-Arnaud, René

Keywords: Bone; Cell Differentiation; Drug Development; Klinefelter Syndrome; Medicinal Chemistry; Metabolic Bone Disease; Osteoblasts; Preclinical Testing

$990,675

The Role of BRIL in the Pathogenesis of Osteogenesis Imperfecta.

Nominated PICIHR2020Project Grant

Principal investigators: Moffatt, Pierre

Keywords: Bone Development; Bone Mineralization; Osteoblast; Osteogenesis Imperfecta; Rare Disease; Transgenic Mouse Models

$669,375

The role of BRIL in the pathogenesis of osteogenesis imperfecta type V.

Nominated PICIHR2014Operating Grant

Principal investigators: Moffatt, Pierre

Keywords: Bone Physiology/Pathology; Cell Biology; Cell Culture; Micro Computed Tomography; Molecular Biology; Osteogenesis Imperfecta; Pcr; Transgenic/Knockin Mouse Models; Western Blotting

$549,170

The role of BRIL in the pathogenesis of osteogenesis imperfecta type V.

Nominated PICIHR2013Operating Grant - PA: Musculoskeletal Health, Arthritis, Skin and Oral Health

Principal investigators: Moffatt, Pierre

Keywords: Bone Physiology/Pathology; Cell Biology; Cell Culture; Micro Computed Tomography; Molecular Biology; Osteogenesis Imperfecta; Pcr; Transgenic/Knockin Mouse Models; Western Blotting

$100,000

The role of hyaluronan in the growth and function of the skeletal system.

Co-investigatorCIHR2012Operating Grant

Principal investigators: Roughley, Peter J

Keywords: Arthritis; Bone; Cartilage; Chondrodysplasia; Development; Growth; Hyaluronan; Knockout Mice

$551,414

The effect of a hybrid and injectible Nanoparticle BMP Delivery System on Bone Regeneration during Distraction Osteogenesis

Co-investigatorCIHR2012Operating Grant

Principal investigators: Hamdy, Reggie C

Keywords: Bone Consolidation; Bone Morphogenetic Proteins; Distraction Osteogenesis; External Fixator; Gene Silencing; Immunohistochemistry; Microct; Mouse Model; Nanoparticle Delivery System; Quantum Dots

$452,508

The role of hyaluronan in the growth and function of the skeletal system.

Co-investigatorCIHR2011Operating Grant - PA: Musculoskeletal Health, Arthritis, Skin and Oral Health

Principal investigators: Roughley, Peter J

Keywords: Arthritis; Bone; Cartilage; Chondrodysplasia; Development; Growth; Hyaluronan; Knockout Mice

$100,000

The Role of Pigment Epithelium Derived Factor During Skeletal Development

Co-investigatorCIHR2011Operating Grant - PA: Musculoskeletal Health, Arthritis, Skin and Oral Health

Principal investigators: Rauch, Frank

Keywords: Biomineralization; Bone Development; Bone Histomorphometry; Bone Remodeling; Knock-Out Mouse

$100,000

Functional and Molecular Characterization of the Novel Chondrocyte-Specific Gene Smpec

Nominated PICIHR2011Operating Grant - PA: Musculoskeletal Health, Arthritis, Skin and Oral Health

Principal investigators: Moffatt, Pierre

Keywords: Chondrocyte; Growth Plate; Membrane Protein; Molecular And Cellular Biology; Proteoglycan; Skeletal Biology; Transgenesis And Knockout

$100,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Something wrong or missing on this profile? Suggest a correction

Pierre Moffatt

Research

Latest papers

Latest funding

Two Novel ACTC1 Variants Cause Arthrogryposis Multiplex Congenita.

Characterisation of Urine-Derived Cells for the Molecular Diagnosis of Rare Disorders.

Tall Stature and Scoliosis Associated With a Novel Homozygous Loss-of-Function Missense Variant in NPR3.

RNA Sequencing of Urine-Derived Cells for the Characterization and Diagnosis of Osteogenesis Imperfecta.

Dominant osteogenesis imperfecta with low bone turnover caused by a heterozygous SP7 variant.

The Osteogenesis Imperfecta Type V Mutant BRIL/IFITM5 Promotes Transcriptional Activation of MEF2, NFATc, and NR4A in Osteoblasts.

Effect of human secretory calcium-binding phosphoprotein proline-glutamine rich 1 protein on Porphyromonas gingivalis and identification of its active portions.

Muscle transcriptome in mouse models of osteogenesis imperfecta.

Calvaria Bone Transcriptome in Mouse Models of Osteogenesis Imperfecta.

A proline rich protein from the gingival seal around teeth exhibits antimicrobial properties against Porphyromonas gingivalis.

A precision medicine approach for treatment of low bone mass in Klinefelter Syndrome

The Role of BRIL in the Pathogenesis of Osteogenesis Imperfecta.

The role of BRIL in the pathogenesis of osteogenesis imperfecta type V.

The role of BRIL in the pathogenesis of osteogenesis imperfecta type V.

The role of hyaluronan in the growth and function of the skeletal system.

The effect of a hybrid and injectible Nanoparticle BMP Delivery System on Bone Regeneration during Distraction Osteogenesis

The role of hyaluronan in the growth and function of the skeletal system.

The Role of Pigment Epithelium Derived Factor During Skeletal Development

Functional and Molecular Characterization of the Novel Chondrocyte-Specific Gene Smpec

Frequent collaborators

Frank Rauch

Antonio Nanci

Peter Roughley

Jacek Majewski

Monzur Murshed

Yojiro Yamanaka