Faculty profile

Yojiro Yamanaka

ResearcherMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Yojiro Yamanaka

Researcher

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
14 publications in the last five years, latest in 2026.
Senior (last) author on 5 recent papers, a sign of leading a research group.
Principal investigator on 5 research grants (4 CIHR, 1 NSERC), most recently in 2021.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Cellular Heterogeneity Crispr Mouse Model Mullerian Duct Organoids Oviduct/Fallopian Tube Reproduction

Latest papers

Increased tissue tension caused by depletion of CLDN3 in the non-neural ectoderm causes neural tube defects in chick embryos.
Journal of cell science · 2026
Mice with the mono-allelic p.R37H Dhdds variant show aberrant glycosylation and interneuron deficits.
Brain : a journal of neurology · 2026
The microtubule-binding protein EML3 is required for mammalian embryonic growth and cerebral cortical development, and Eml3 null mice are a model of cobblestone brain malformation.
eLife · 2026

All 32 publications

Latest funding

Molecular, cellular, and physiological response to DNA damage, genotoxic stress, and cell death across living systems: RadSource RS-2000 X-ray irradiator
NSERC · 2023 · Co-investigator
$150,000
Understanding cellular heterogeneity in the oviductal epithelium and tubo-ovarian cancer susceptibility.
CIHR · 2021 · Nominated PI
$952,425
Functional and genetic susceptibility to progressive cryptococcal pneumonia
CIHR · 2018 · Co-investigator
$1,021,276

All 9 grants and awards

32 publications.

Increased tissue tension caused by depletion of CLDN3 in the non-neural ectoderm causes neural tube defects in chick embryos.

Legere EA, Dumont M, Dias JA, Yamanaka Y, Galea GL, Ryan AK

Journal of cell science2026

DOI: 10.1242/jcs.264758 PMID: 42605241

Mice with the mono-allelic p.R37H Dhdds variant show aberrant glycosylation and interneuron deficits.

Da Silva A, Fallah MS, Tene Tadoum SB, Fazeli M, Muffels IJJ, Wang S, Grenier F, Budhraja R, Sturiale L, Messina A, Giladi M, Taherzadeh M, Bonneil É, Khan S, Vruchte DT, Yamanaka Y, Di Cristo G, Hamdan FF, Platt FM, Tomatsu S, Haitin Y, Kozicz T, Thibault P, Garozzo D, Pandey A, Morava E, Rossignol E, Pshezhetsky AV

Brain : a journal of neurology2026

DOI: 10.1093/brain/awag304 PMID: 42725623

The microtubule-binding protein EML3 is required for mammalian embryonic growth and cerebral cortical development, and Eml3 null mice are a model of cobblestone brain malformation.

Carrier I, Diez E, Piscopo VE, Bechstedt S, van Bokhoven H, Srour M, Berghuis AM, Stifani S, Yamanaka Y, McInnes R

eLife2026

DOI: 10.7554/elife.107102 PMID: 42423433

Structural and epistatic regulatory variants cause hallmark white spotting in cattle.

Jivanji S, Wilkinson E, Tang L, Tiplady KM, Yeates A, Harland C, Gray C, Couldrey C, Worth G, Gamache I, Desjardins J, Tabares JAA, Yamanaka N, McNaughton L, Brennan L, Cloutier MP, Cowan M, Ellison R, Fransen T, Monehan T, Spelman RJ, Snell RG, Charlier C, Yamanaka Y, Garrick D, Mort R, Littlejohn MD

Science advances2025

DOI: 10.1126/sciadv.adt5913 PMID: 41237223

Aging-Associated Vacuolation of Multi-Ciliated Cells in the Distal Mouse Oviduct Reflects Unique Cell Identity and Luminal Microenvironment.

Harwalkar K, Yamanaka N, Pacis AS, Zhao S, Teng K, Pitman W, Taskar M, Lynn V, Thornton AF, Ford MJ, Yamanaka Y

Aging cell2025Senior author

DOI: 10.1111/acel.70051 PMID: 40310729

Impact of eIF2α phosphorylation on the translational landscape of mouse embryonic stem cells.

Amiri M, Kiniry SJ, Possemato AP, Mahmood N, Basiri T, Dufour CR, Tabatabaei N, Deng Q, Bellucci MA, Harwalkar K, Stokes MP, Giguère V, Kaufman RJ, Yamanaka Y, Baranov PV, Tahmasebi S, Sonenberg N

Cell reports2024

DOI: 10.1016/j.celrep.2023.113615 PMID: 38159280

CD133/Prom1 marks proximal mouse oviduct epithelial progenitors and adult epithelial cells with a low generative capacity.

Ford MJ, Harwalkar K, Kazemdarvish H, Yamanaka N, Yamanaka Y

Biology open2023Senior author

DOI: 10.1242/bio.059963 PMID: 37605939

ZMYM2 is essential for methylation of germline genes and active transposons in embryonic development.

Graham-Paquin AL, Saini D, Sirois J, Hossain I, Katz MS, Zhuang QK, Kwon SY, Yamanaka Y, Bourque G, Bouchard M, Pastor WA

Nucleic acids research2023

DOI: 10.1093/nar/gkad540 PMID: 37395395

N-acetylneuraminate pyruvate lyase controls sialylation of muscle glycoproteins essential for muscle regeneration and function.

Da Silva A, Dort J, Orfi Z, Pan X, Huang S, Kho I, Heckel E, Muscarnera G, van Vliet PP, Sturiale L, Messina A, Romeo DA, van Karnebeek CDM, Wen XY, Hinek A, Molina T, Andelfinger G, Ellezam B, Yamanaka Y, Olivos HJ, Morales CR, Joyal JS, Lefeber DJ, Garozzo D, Dumont NA, Pshezhetsky AV

Science advances2023

DOI: 10.1126/sciadv.ade6308 PMID: 37390204

Glucosamine amends CNS pathology in mucopolysaccharidosis IIIC mouse expressing misfolded HGSNAT.

Pan X, Taherzadeh M, Bose P, Heon-Roberts R, Nguyen ALA, Xu T, Pará C, Yamanaka Y, Priestman DA, Platt FM, Khan S, Fnu N, Tomatsu S, Morales CR, Pshezhetsky AV

The Journal of experimental medicine2022

DOI: 10.1084/jem.20211860 PMID: 35704026

Molecular, cellular, and physiological response to DNA damage, genotoxic stress, and cell death across living systems: RadSource RS-2000 X-ray irradiator

Co-investigatorNSERC2023Research Tools and Instruments

Principal investigators: Nijnik, Anastasia

$150,000

Understanding cellular heterogeneity in the oviductal epithelium and tubo-ovarian cancer susceptibility.

Nominated PICIHR2021Project Grant

Principal investigators: Yamanaka, Yojiro

Keywords: Cellular Heterogeneity; Crispr; Mouse Model; Mullerian Duct; Organoids; Oviduct/Fallopian Tube; Reproduction

$952,425

Functional and genetic susceptibility to progressive cryptococcal pneumonia

Co-investigatorCIHR2018Project Grant

Principal investigators: Qureshi, Salman T

Keywords: Bone Marrow Chimera And Adoptive Cell Transfer; Candidate Gene Analysis; Complex Trait Analysis; Congenic And Subcongenic Mouse Strains; Cryptococcus Neoformans; Fungal Pneumonia And Lung Inflammation; Gene Expression Analysis; Genetic Susceptibility To Infection; Genome Editing; Mouse Models

$1,021,276

Ex vivo phenotyping of cells, organoids and embryos.

Co-investigatorNSERC2018Research Tools and Instruments

Principal investigators: Bouchard, Maxime

$150,000

Mechanisms of Met activation in cancer and therapeutic intervention

Co-investigatorCIHR2014Foundation Grant

Principal investigators: Park, Morag

Keywords: Cell Signalling Networks; Gastric Cancer; Gene Expression; Growth Factor; Intracellular Trafficking; Oncogenic Activation; Preclinical Models; Receptor Tyrosine Kinase; Resistance; Triple Negative Breast Cancer

$3,507,282

Investigating the transition from head to trunk formation in vertebrate development

Principal investigatorNSERC2012Discovery Grants Program - Individual

Principal investigators: Yamanaka, Yojiro

$180,000

Cell polarity and generation of the first distinct lineages in the mouse embryo

Nominated PICIHR2011Maud Menten New Principal Investigator Prize - Biomedical

Principal investigators: Yamanaka, Yojiro

Keywords: Asymmetric Division; Blastocyst; Cell Adhesion; Cell Polarity; Cell Sorting; Cortical Tension; Development; Lineage; Live Imaging; Mouse Embryo

$1,000

Cell polarity and generation of the first distinct lineages in the mouse embryo

Nominated PICIHR2010Operating Grant - PA: Institute of Genetics (Bridge Funding)

Principal investigators: Yamanaka, Yojiro

Keywords: Asymmetric Division; Blastocyst; Cell Adhesion; Cell Polarity; Cell Sorting; Cortical Tension; Development; Lineage; Live Imaging; Mouse Embryo

$100,000

Cell polarity and generation of the first distinct lineages in the mouse embryo

Nominated PICIHR2010Operating Grant

Principal investigators: Yamanaka, Yojiro

Keywords: Asymmetric Division; Blastocyst; Cell Adhesion; Cell Polarity; Cell Sorting; Cortical Tension; Development; Lineage; Live Imaging; Mouse Embryo

$744,545

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Yojiro Yamanaka

Research

Latest papers

Latest funding

Increased tissue tension caused by depletion of CLDN3 in the non-neural ectoderm causes neural tube defects in chick embryos.

Mice with the mono-allelic p.R37H Dhdds variant show aberrant glycosylation and interneuron deficits.

The microtubule-binding protein EML3 is required for mammalian embryonic growth and cerebral cortical development, and Eml3 null mice are a model of cobblestone brain malformation.

Structural and epistatic regulatory variants cause hallmark white spotting in cattle.

Aging-Associated Vacuolation of Multi-Ciliated Cells in the Distal Mouse Oviduct Reflects Unique Cell Identity and Luminal Microenvironment.

Impact of eIF2&#x3b1; phosphorylation on the translational landscape of mouse embryonic stem cells.

CD133/Prom1 marks proximal mouse oviduct epithelial progenitors and adult epithelial cells with a low generative capacity.

ZMYM2 is essential for methylation of germline genes and active transposons in embryonic development.

N-acetylneuraminate pyruvate lyase controls sialylation of muscle glycoproteins essential for muscle regeneration and function.

Glucosamine amends CNS pathology in mucopolysaccharidosis IIIC mouse expressing misfolded HGSNAT.

Molecular, cellular, and physiological response to DNA damage, genotoxic stress, and cell death across living systems: RadSource RS-2000 X-ray irradiator

Understanding cellular heterogeneity in the oviductal epithelium and tubo-ovarian cancer susceptibility.

Functional and genetic susceptibility to progressive cryptococcal pneumonia

Ex vivo phenotyping of cells, organoids and embryos.

Mechanisms of Met activation in cancer and therapeutic intervention

Investigating the transition from head to trunk formation in vertebrate development

Cell polarity and generation of the first distinct lineages in the mouse embryo

Cell polarity and generation of the first distinct lineages in the mouse embryo

Cell polarity and generation of the first distinct lineages in the mouse embryo

Frequent collaborators

Nahum Sonenberg

Maxime Bouchard

Xiang-Jiao Yang

Arkady Khoutorsky

Guillaume Bourque

Pierre Thibault

Myriam Srour

Paul Goodyer

Janet Rossant

Masha Prager-Khoutorsky

Susanne Bechstedt

Tommy Alain

Stefano Stifani

Myriam Srour

Gregor Andelfinger

Pierre Moffatt

David Lohnes

Frank Rauch

Impact of eIF2α phosphorylation on the translational landscape of mouse embryonic stem cells.