This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université Laval directory, so their courses may be missing. Find their university profile.
Research
Latest papers
MicroRNA-224 orchestrates BMP and TGFβ signaling and is a therapeutic target in preclinical pulmonary arterial hypertension.
Science translational medicine · 2026
Impaired Lung BCAA Metabolism Promotes Ferroptosis and Resultant Pulmonary Arterial Hypertension-Associated Hepatopathy.
JACC. Basic to translational science · 2026
Pulmonary arterial hypertension induces a metabolic and inflammatory hepatopathy.
The Journal of clinical investigation · 2026
Latest funding
- $140,000
Airway microbiome as a novel therapeutic target for pulmonary hypertension
CIHR · 2025 · Supervisor
- $1,090,126
The Impact of Chronobiology on Pulmonary Arterial Hypertension: Insights into the Core Clock Protein Rev-Erb
CIHR · 2025 · Nominated PI
- $856,800
Targeting Integrin Signaling to Alleviate Remodeling in Pulmonary Arteries and the Right Ventricle in Pulmonary Hypertension
CIHR · 2024 · Co-investigator
40 publications.
MicroRNA-224 orchestrates BMP and TGFβ signaling and is a therapeutic target in preclinical pulmonary arterial hypertension.
Bikou O, Halouani A, Sun Y, Bisserier M, Eisenacher C, Antar SA, Avramopoulos P, Santos-Gallego CG, Swarts C, Kohlbrenner E, Ishikawa K, Humbert M, Hajjar RJ, Lax A, Engelhardt S, Walsh MJ, Bonnet S, Hadri L, Sassi Y
Impaired Lung BCAA Metabolism Promotes Ferroptosis and Resultant Pulmonary Arterial Hypertension-Associated Hepatopathy.
Blake MJ, Hong J, Brownstein A, Rhodes CJ, Swietlik EM, Blake JC, Moon RA, Hartweck LM, Mendelson JB, Prisco SZ, Markowski T, Higgins L, Murray K, Guerrero C, Breuils-Bonnet S, Provencher S, Pepke-Zaba J, Toshner M, Wilkins M, Bonnet S, Prins KW
Pulmonary arterial hypertension induces a metabolic and inflammatory hepatopathy.
Blake MJ, Prins SE, Blake J, Hartweck LM, Mendelson JB, Provencher S, Breuils-Bonnet S, Bonnet S, Prins KW
Alternative Polyadenylation Signatures Distinguish Maladaptive Right Ventricular Remodeling in Pulmonary Hypertension: Implications for RNA-Based Diagnostics and Therapeutics.
Subramaniam J, Jonnakuti V, Collum SD, Martineau S, Huang KL, Breuils-Bonnet S, Frump AL, Akkanti BH, Patel JA, Patel MK, Salas de Armas I, Lefebvre IN, Radovancevic R, Blanco E, Wagner EJ, Gregoric I, Nathan S, Kar B, Provencher S, Bonnet S, Potus F, Yalamanchili HK, Karmouty-Quintana H
IGFBP7 Contributes to Endothelial-to-Mesenchymal Transition and Serves as a Biomarker for Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.
Deng L, Wang Z, Boucherat O, Leng B, Cao C, He M, Cai Z, Chen Z, Wu G, Bonnet S, Wei W, Bian JS
Protein biomarkers in pulmonary arterial hypertension: advances, clinical relevance, and translational challenges.
Niu Y, Tian J, Provencher S, Bonnet S, Boucherat O, Potus F, Gou D
Pharmacological inhibition of Epac1 protects against pulmonary fibrosis by blocking FoxO3a neddylation.
Jankowski K, Lemay SE, Lozano-Ojalvo D, Pérez-Rodríguez L, Sauvaget M, Breuils-Bonnet S, Formoso K, Jagana V, Ochoa MT, Zhang S, Milara J, Cortijo J, Turnbull IC, Provencher S, Bonnet S, Ochando J, Lezoualc'h F, Bisserier M, Hadri L
Single-Cell and Spatial Transcriptomics Identified Fatty Acid-Binding Proteins Controlling Endothelial Glycolytic and Arterial Programming in Pulmonary Hypertension.
Liu B, Yi D, Li S, Ramirez K, Xia X, Cao Y, Zhao H, Tripathi A, Qiu S, Kala M, Rafikov R, Gu H, de Jesus Perez V, Lemay SE, Glembotski CC, Knox KS, Bonnet S, Kalinichenko VV, Zhao YY, Fallon MB, Boucherat O, Dai Z
Deficiency of the Deubiquitinase UCHL1 Attenuates Pulmonary Arterial Hypertension.
Tang H, Gupta A, Morrisroe SA, Bao C, Schwantes-An TH, Gupta G, Liang S, Sun Y, Chu A, Luo A, Ramamoorthi Elangovan V, Sangam S, Shi Y, Naidu SR, Jheng JR, Ciftci-Yilmaz S, Warfel NA, Hecker L, Mitra S, Coleman AW, Lutz KA, Pauciulo MW, Lai YC, Javaheri A, Dharmakumar R, Wu WH, Flaherty DP, Karnes JH, Breuils-Bonnet S, Boucherat O, Bonnet S, Yuan JX, Jacobson JR, Duarte JD, Nichols WC, Garcia JGN, Desai AA
Seeing pulmonary hypertension through a paediatric lens: a viewpoint.
Agarwal S, Fineman J, Cornfield DN, Alvira CM, Zamanian RT, Goss K, Yuan K, Bonnet S, Boucherat O, Pullamsetti S, Alcázar MA, Goncharova E, Kudryashova TV, Nicolls MR, de Jesús Pérez V
Airway microbiome as a novel therapeutic target for pulmonary hypertension
Principal investigators: Yang, Haopu
Keywords: Airway Microbiome; Microbiome Engineering; Pulmonary Hypertension
The Impact of Chronobiology on Pulmonary Arterial Hypertension: Insights into the Core Clock Protein Rev-Erb
Principal investigators: Bonnet, Sébastien; Provencher, Steeve
Keywords: Pulmonary Hypertension
Targeting Integrin Signaling to Alleviate Remodeling in Pulmonary Arteries and the Right Ventricle in Pulmonary Hypertension
Principal investigators: Boucherat, Olivier
Keywords: Pulmonary Hypertension; Pulmonary Vascular Disease
Targeting Mitosis and Senescence to Reverse Pulmonary Hypertension: A Promising Therapeutic Strategy
Principal investigators: Provencher, Steeve
Keywords: Pulmonary Hypertension, Lung Disease
Exploring the Interplay between Metabolic and Epigenetic Signalling Pathways to Regulate Neointima Hyperplasia
Principal investigators: Bonnet, Sébastien
Keywords: Neointimal Hyperplasia; Vascular Diseases; Vascular Smooth Muscle Cells
Targeting Hypusine signaling: an opportunity to counter pulmonary vascular remodelling in pulmonary arterial hypertension
Principal investigators: Bonnet, Sébastien
Keywords: Pulmonary Hypertension, Vascular Disease
ATP Citrate Lyase: an attractive target at the nexus of metabolic and epigenetic alterations in pulmonary arterial hypertension
Principal investigators: Boucherat, Olivier
Keywords: Pulmonary Hypertension; Pulmonary Vascular Disease
A Canadian preclinical multicenter collaborative to improve acute and chronic lung disease research
Principal investigators: Lalu, Manoj M; Fergusson, Dean A; Stewart, Duncan J
Keywords: Acute Lung Injury; Acute Respiratory Distress Syndrome; Cardiac Disease; Chronic Lung Disease; Multicenter Preclinical Study; Pulmonary Arterial Hypertension; Reproducibility; Risk Of Bias
The anti-oxidative DNA damage protein MTH1, the novel pulmonary hypertension Achilles heel.
Principal investigators: Bonnet, Sébastien
Keywords: Oxidative Damage; Pulmonary Hypertension
BRD4 Inhibition in Pulmonary Arterial Hypertension: a Phase 2 Clinical Trial
Principal investigators: Provencher, Steeve
Keywords: Bromodomain; Epigenetic Eraser; Epigenetics; Pulmonary Arterial Hypertension; Pulmonary Hypertension
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Jason Weatherald and Jason Weatherald: 63 shared papers
- Steeve Provencher and Olivier Boucherat: 40 shared papers
- Steeve Provencher and Roxane Paulin: 29 shared papers
- Sébastien Bonnet and Steeve Provencher: 25 shared papers
- Roxane Paulin and Olivier Boucherat: 22 shared papers
- Sébastien Bonnet and Olivier Boucherat: 14 shared papers
- Steeve Provencher and Francois Potus: 8 shared papers
- Sébastien Bonnet and Francois Potus: 6 shared papers
- Steeve Provencher and Gopinath Sutendra: 5 shared papers
- Steeve Provencher and Jason Weatherald: 5 shared papers
- Steeve Provencher and Jason Weatherald: 5 shared papers
- Sébastien Bonnet and Roxane Paulin: 4 shared papers
- Olivier Boucherat and Francois Potus: 4 shared papers
- Sébastien Bonnet and Gopinath Sutendra: 3 shared papers
- Sébastien Bonnet and Jason Weatherald: 2 shared papers
- Roxane Paulin and Gopinath Sutendra: 2 shared papers
- Sébastien Bonnet and Jason Weatherald: 1 shared paper
- Sébastien Bonnet and Kimberly Dunham-Snary: 1 shared paper
- Steeve Provencher and Kimberly Dunham-Snary: 1 shared paper
- Francois Potus and Kimberly Dunham-Snary: 1 shared paper
- Medicine
- Médecine
- Physical Therapy
- Biomedical and Molecular Sciences
- Other
Co-authors at Université Laval, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Steeve Provencher
Médecine
25 shared papers, latest 2026
Olivier Boucherat
Faculty
14 shared papers, latest 2026
Francois Potus
Faculty
6 shared papers, latest 2022
Roxane Paulin
Medicine
4 shared papers, latest 2018
Gopinath Sutendra
Medicine
3 shared papers, latest 2020
Jason Weatherald
Medicine
2 shared papers, latest 2022
Jason Weatherald
Physical Therapy
1 shared papers, latest 2022
Kimberly Dunham-Snary
Biomedical and Molecular Sciences
1 shared papers, latest 2017
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