Jean-Claude Lavoie

Research

Antioxidant Bronchopulmonary Dysplasia Glutathione Lung Histology Newborn Guinea Pig Oxidative Stress Parenteral Nutrition Peroxide

Latest papers

Glutathione Supplementation in Parenteral Nutrition to Prevent Oxidative Stress Related Complications in Preterm Infants: A Narrative Review of Preclinical Efficacy and Safety Profile.
Nutrients · 2026 · first author
Glutathione Supplementation Prevents Neonatal Parenteral Nutrition-Induced Short- and Long-Term Epigenetic and Transcriptional Disruptions of Hepatic H2O2 Metabolism in Guinea Pigs.
Nutrients · 2024 · senior author
Parenteral Cysteine Supplementation in Preterm Infants: One Size Does Not Fit All.
Biomedicines · 2023 · senior author

All 24 publications

Latest funding

Preventing bronchopulmonary dysplasia in preterm infants by adding glutathione to their parenteral nutrition, a translational study
CIHR · 2016 · Nominated PI
$753,035
Maternal Omega-3 supplementation to reduce Bronchopulmonary Dysplasia in very Preterm Infants : A Randomized Controlled Trial (MOBYDIck Trial)
CIHR · 2014 · Co-investigator
$2,626,763
Risk of Chronic Diseases in Young Adults Born Preterm: Relationship with Inflammation and Oxidative Stress Biomarkers
CIHR · 2013 · Co-investigator
$471,215

All 7 grants and awards

24 publications.

01

Glutathione Supplementation in Parenteral Nutrition to Prevent Oxidative Stress Related Complications in Preterm Infants: A Narrative Review of Preclinical Efficacy and Safety Profile.

Lavoie JC, Mohamed I

Nutrients2026First author

DOI: 10.3390/nu18132092 PMID: 42451095

02

Glutathione Supplementation Prevents Neonatal Parenteral Nutrition-Induced Short- and Long-Term Epigenetic and Transcriptional Disruptions of Hepatic H2O2 Metabolism in Guinea Pigs.

Mungala Lengo A, Mohamed I, Lavoie JC

Nutrients2024Senior author

DOI: 10.3390/nu16060849 PMID: 38542762

03

Parenteral Cysteine Supplementation in Preterm Infants: One Size Does Not Fit All.

Mohamed I, El Raichani N, Otis AS, Lavoie JC

Biomedicines2023Senior author

DOI: 10.3390/biomedicines12010063 PMID: 38255171

04

Cardiopulmonary response to exercise in adults born very preterm.

Delfrate J, Girard-Bock C, Curnier D, Périé-Curnier D, Cloutier A, Gascon G, Landry JS, Mâsse B, Stickland MK, Nuyt AM, Luu TM, HAPI Collaborating Group, Adomi M, Alos N, Al Simaani A, Bertagnolli M, Bigras JL, Ravizzoni Dartora D, Ducruet T, El-Jalbout R, Fernandes RO, Flahault A, Gyger G, Hamel P, Henderson M, Lavoie JC, Lapeyraque AL, Mian MOR, Orlando V, Paquette K, Xie LF

The European respiratory journal2023

DOI: 10.1183/13993003.00503-2023 PMID: 37734855

05

Neonatal Vitamin C and Cysteine Deficiencies Program Adult Hepatic Glutathione and Specific Activities of Glucokinase, Phosphofructokinase, and Acetyl-CoA Carboxylase in Guinea Pigs' Livers.

Teixeira V, Mohamed I, Lavoie JC

Antioxidants (Basel, Switzerland)2021Senior author

DOI: 10.3390/antiox10060953 PMID: 34204849

06

Parenteral nutrition and oxidant stress in the newborn: A narrative review.

Lavoie JC, Chessex P

Free radical biology & medicine2019First author

DOI: 10.1016/j.freeradbiomed.2019.02.020 PMID: 30807828

07

Glutathione Supplementation of Parenteral Nutrition Prevents Oxidative Stress and Sustains Protein Synthesis in Guinea Pig Model.

Morin G, Guiraut C, Perez Marcogliese M, Mohamed I, Lavoie JC

Nutrients2019Senior author

DOI: 10.3390/nu11092063 PMID: 31484318

08

Sex-Specificity of Oxidative Stress in Newborns Leading to a Personalized Antioxidant Nutritive Strategy.

Lavoie JC, Tremblay A

Antioxidants (Basel, Switzerland)2018First author

DOI: 10.3390/antiox7040049 PMID: 29584624

09

Adult Consequences of Extremely Preterm Birth: Cardiovascular and Metabolic Diseases Risk Factors, Mechanisms, and Prevention Avenues.

Nuyt AM, Lavoie JC, Mohamed I, Paquette K, Luu TM

Clinics in perinatology2017

DOI: 10.1016/j.clp.2017.01.010 PMID: 28477663

10

Shielding Parenteral Nutrition From Light Improves Survival Rate in Premature Infants.

Chessex P, Laborie S, Nasef N, Masse B, Lavoie JC

JPEN. Journal of parenteral and enteral nutrition2017Senior author

DOI: 10.1177/0148607115606407 PMID: 26376662

Preventing bronchopulmonary dysplasia in preterm infants by adding glutathione to their parenteral nutrition, a translational study

Nominated PICIHR2016Project Grant

Principal investigators: Lavoie, Jean-Claude; Mohamed, Ibrahim

Keywords: Antioxidant; Bronchopulmonary Dysplasia; Glutathione; Lung Histology; Newborn Guinea Pig; Oxidative Stress; Parenteral Nutrition; Peroxide; Prematurity; Redox Potential

$753,035

Maternal Omega-3 supplementation to reduce Bronchopulmonary Dysplasia in very Preterm Infants : A Randomized Controlled Trial (MOBYDIck Trial)

Co-investigatorCIHR2014Operating Grant

Principal investigators: Marc, Isabelle; Fraser, William D; Lacaze-Masmonteil, Thierry; Lavoie, Pascal; Mâsse, Benoît R; Nuyt, Anne Monique

Keywords: Breastfeeding; Bronchopulmonary Dysplasia; Child Neurodevelopment; Neonatal Nutrition; Omega-3 Fatty Acids; Perinatality; Prematurity; Randomized Controlled Trial

$2,626,763

Risk of Chronic Diseases in Young Adults Born Preterm: Relationship with Inflammation and Oxidative Stress Biomarkers

Co-investigatorCIHR2013Operating Grant

Principal investigators: Nuyt, Anne Monique; Luu, Thuy Mai

Keywords: Cardio Metabolic Disease; Chronic Health Disease; Clinical Study; Developmental Programing Of Adult Diseases; Inflammation; Oxidative Stress; Prematurity

$471,215

Maternal Omega-3 supplementation to reduce Bronchopulmonary Dysplasia in very Preterm Infants : A Randomized Controlled Trial (MOBYDIck Trial)

Co-investigatorCIHR2013Operating Grant

Principal investigators: Marc, Isabelle; Fraser, William D; Lacaze-Masmonteil, Thierry; Lavoie, Pascal; Mâsse, Benoît R; Nuyt, Anne Monique

Keywords: Breastfeeding; Bronchopulmonary Dysplasia; Child Neurodevelopment; Neonatal Nutrition; Omega-3 Fatty Acids; Perinatality; Prematurity; Randomized Controlled Trial

$100,000

Impact de l'ascorbylperoxyde sur le développement pulmonaire du nouveau-né

Nominated PICIHR2011Operating Grant

Principal investigators: Lavoie, Jean-Claude

Keywords: Ascorbylperoxyde; Dysplasie Broncho-Pulmonaire; Glutathion; Nouveau-Né; Nutrition Parentérale; Poumon; Prématurité; Stress Oxydant

$397,630

Neonatal oxygen exposure leads to premature aging of the vascular system and the kidneys: role in adult hypertension

Principal investigatorCIHR2010Operating Grant

Principal investigators: Nuyt, Anne Monique; Lavoie, Jean-Claude

Keywords: Aging; Developmental Programming; Hypertension; Oxidative Stress; Oxygen

$566,020

Consequences of neonatal infusion of oxidant molecules associated with parenteral nutrition on energy metabolism later in life

Nominated PICIHR2009Operating Grant - PA: Inst of Nutrition, Metabolism and Diabetes -Bridge Funding

Principal investigators: Lavoie, Jean-Claude

Keywords: Complications Of Prematurity; Energy Metabolism; Fatty Liver; Glycolysis; Guinea Pig Model

$100,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Subject: Prospective PhD student: Antioxidant Dear Professor Lavoie, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Glutathione Supplementation in Parenteral Nutrition to Prevent Oxidative Stress Related Complications in Preterm Infants: A Narrative Review of Preclinical Efficacy and Safety Profile." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Jean-Claude Lavoie

Research

Latest papers

Latest funding

Glutathione Supplementation in Parenteral Nutrition to Prevent Oxidative Stress Related Complications in Preterm Infants: A Narrative Review of Preclinical Efficacy and Safety Profile.

Glutathione Supplementation Prevents Neonatal Parenteral Nutrition-Induced Short- and Long-Term Epigenetic and Transcriptional Disruptions of Hepatic H2O2 Metabolism in Guinea Pigs.

Parenteral Cysteine Supplementation in Preterm Infants: One Size Does Not Fit All.

Cardiopulmonary response to exercise in adults born very preterm.

Neonatal Vitamin C and Cysteine Deficiencies Program Adult Hepatic Glutathione and Specific Activities of Glucokinase, Phosphofructokinase, and Acetyl-CoA Carboxylase in Guinea Pigs' Livers.

Parenteral nutrition and oxidant stress in the newborn: A narrative review.

Glutathione Supplementation of Parenteral Nutrition Prevents Oxidative Stress and Sustains Protein Synthesis in Guinea Pig Model.

Sex-Specificity of Oxidative Stress in Newborns Leading to a Personalized Antioxidant Nutritive Strategy.

Adult Consequences of Extremely Preterm Birth: Cardiovascular and Metabolic Diseases Risk Factors, Mechanisms, and Prevention Avenues.

Shielding Parenteral Nutrition From Light Improves Survival Rate in Premature Infants.

Preventing bronchopulmonary dysplasia in preterm infants by adding glutathione to their parenteral nutrition, a translational study

Maternal Omega-3 supplementation to reduce Bronchopulmonary Dysplasia in very Preterm Infants : A Randomized Controlled Trial (MOBYDIck Trial)

Risk of Chronic Diseases in Young Adults Born Preterm: Relationship with Inflammation and Oxidative Stress Biomarkers

Maternal Omega-3 supplementation to reduce Bronchopulmonary Dysplasia in very Preterm Infants : A Randomized Controlled Trial (MOBYDIck Trial)

Impact de l'ascorbylperoxyde sur le développement pulmonaire du nouveau-né

Neonatal oxygen exposure leads to premature aging of the vascular system and the kidneys: role in adult hypertension

Consequences of neonatal infusion of oxidant molecules associated with parenteral nutrition on energy metabolism later in life

Frequent collaborators

Ibrahim Mohamed

Emile Levy

Devendra Amre

Benoît Mâsse

Mariane Bertagnolli

Valerie Marcil

Mariane Bertagnolli

Sylvain Chemtob

Pierre Lachapelle

Christian Deschepper

Pierre Hardy